SUFU Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description suppressor of fused homolog (Drosophila)|The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 51684)
External Link http://www.ncbi.nlm.nih.gov/gene/51684
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109 interacting proteins for SUFU from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1E casein kinase 1, epsilon
CUL1 cullin 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
FBXL17 F-box and leucine-rich repeat protein 17
FUZ fuzzy planar cell polarity protein
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GLIS3 GLIS family zinc finger 3
GSK3B glycogen synthase kinase 3 beta
HDX highly divergent homeobox
HMGA1 high mobility group AT-hook 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IFT122 intraflagellar transport 122
IFT172 intraflagellar transport 172
IFT52 intraflagellar transport 52
IFT57 intraflagellar transport 57
IFT88 intraflagellar transport 88
INTU inturned planar cell polarity protein
KIF3A kinesin family member 3A
KIF7 kinesin family member 7
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LGALS3 lectin, galactoside-binding, soluble, 3
MAX MYC associated factor X
MID1IP1 MID1 interacting protein 1
MKS1 Meckel syndrome, type 1
NCOA3 nuclear receptor coactivator 3
NRF1 nuclear respiratory factor 1
OFD1 oral-facial-digital syndrome 1
PEX26 peroxisomal biogenesis factor 26
PIAS1 protein inhibitor of activated STAT, 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTCH1 patched 1
QPRT quinolinate phosphoribosyltransferase
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPGRIP1L RPGRIP1-like
SAP18 Sin3A-associated protein, 18kDa
SETDB1 SET domain, bifurcated 1
SHH sonic hedgehog
SIN3A SIN3 transcription regulator family member A
SKP1 S-phase kinase-associated protein 1
SMO smoothened, frizzled class receptor
STK36 serine/threonine kinase 36
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TTC21B tetratricopeptide repeat domain 21B
UBC ubiquitin C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
ZNF219 zinc finger protein 219
ZNF263 zinc finger protein 263
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747
ZNF764 zinc finger protein 764