SUMO1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description small ubiquitin-like modifier 1|This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7341)
External Link https://ncbi.nlm.nih.gov/gene/7341
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Genes

497 genes differentially expressed following the SUMO1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MMP1 matrix metallopeptidase 1 0.0165563
IPO13 importin 13 0.0162943
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0147319
S100A8 S100 calcium binding protein A8 0.0129965
SFRP1 secreted frizzled-related protein 1 0.0118724
SVIL supervillin 0.0101385
HSPB1 heat shock 27kDa protein 1 0.00997284
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00980196
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00932802
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00919132
CXCL10 chemokine (C-X-C motif) ligand 10 0.00883088
XPO7 exportin 7 0.00883062
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00882273
CCL19 chemokine (C-C motif) ligand 19 0.00880341
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00873989
MSMB microseminoprotein, beta- 0.00866399
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00863368
AKR1C3 aldo-keto reductase family 1, member C3 0.00856208
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00818746
CXCL11 chemokine (C-X-C motif) ligand 11 0.0081815
BLNK B-cell linker 0.00810696
KLK3 kallikrein-related peptidase 3 0.00796513
FXYD2 FXYD domain containing ion transport regulator 2 0.00789959
ALOX5 arachidonate 5-lipoxygenase 0.00788184
PFN2 profilin 2 0.00786311
AKR1C1 aldo-keto reductase family 1, member C1 0.00785069
CXCL9 chemokine (C-X-C motif) ligand 9 0.00779236
S100A9 S100 calcium binding protein A9 0.00775597
TFPI2 tissue factor pathway inhibitor 2 0.00767639
IRS1 insulin receptor substrate 1 0.00762846
MAOA monoamine oxidase A 0.00747246
RRM2 ribonucleotide reductase M2 0.00744586
COL4A5 collagen, type IV, alpha 5 0.00741011
BEX1 brain expressed, X-linked 1 0.00733425
TM9SF3 transmembrane 9 superfamily member 3 0.00733163
FASN fatty acid synthase 0.00729363
SH3BGRL SH3 domain binding glutamate-rich protein like 0.0072308
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00723056
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.0072
SAMD4A sterile alpha motif domain containing 4A 0.00719157
MEIS2 Meis homeobox 2 0.00716444
PBX1 pre-B-cell leukemia homeobox 1 0.00716068
ARID1A AT rich interactive domain 1A (SWI-like) 0.0071056
ACP3 acid phosphatase 3 0.00710549
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00708348
CXCL13 chemokine (C-X-C motif) ligand 13 0.00706223
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00705743
RPL10 ribosomal protein L10 0.00705106
ECHDC2 enoyl CoA hydratase domain containing 2 0.00702167
AKR1C2 aldo-keto reductase family 1, member C2 0.00702166
KYNU kynureninase 0.00701901
SPRED2 sprouty-related, EVH1 domain containing 2 0.00694631
C3 complement component 3 0.00693015
ADAMDEC1 ADAM-like, decysin 1 0.00692154
TNS1 tensin 1 0.00691169
PPL periplakin 0.00682874
HLA-DOB major histocompatibility complex, class II, DO beta 0.00680016
NIBAN1 niban apoptosis regulator 1 0.00679248
SHB Src homology 2 domain containing adaptor protein B 0.00677772
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00673331
PRUNE2 prune homolog 2 (Drosophila) 0.00668736
AHSP alpha hemoglobin stabilizing protein 0.00667927
PCGF2 polycomb group ring finger 2 0.00667432
TGM2 transglutaminase 2 0.00664402
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00664293
SAFB2 scaffold attachment factor B2 0.00662333
AMOTL2 angiomotin like 2 0.00661526
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00660599
MSLN mesothelin 0.00659503
DES desmin 0.00652248
ARHGAP29 Rho GTPase activating protein 29 0.00651616
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.00651599
C7 complement component 7 0.00651257
CAPG capping protein (actin filament), gelsolin-like 0.00650781
ZNF395 zinc finger protein 395 0.00650716
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00650695
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00647689
KCTD12 potassium channel tetramerization domain containing 12 0.00647352
LYZ lysozyme 0.00646894
NISCH nischarin 0.00646823
CCL20 chemokine (C-C motif) ligand 20 0.00646729
G6PD glucose-6-phosphate dehydrogenase 0.00645284
SRGN serglycin 0.00643653
PLXNB2 plexin B2 0.00642842
ENO2 enolase 2 (gamma, neuronal) 0.00642509
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00641655
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00640927
BASP1 brain abundant, membrane attached signal protein 1 0.00639458
PXN paxillin 0.00637955
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.0063765
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00637083
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00637074
ZBTB18 zinc finger and BTB domain containing 18 0.00635591
PRPF4B pre-mRNA processing factor 4B 0.00633526
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00630516
TSPAN7 tetraspanin 7 0.00627965
HTRA1 HtrA serine peptidase 1 0.00626415
PEG10 paternally expressed 10 0.00626155
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00624596
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.00622715
KLK2 kallikrein-related peptidase 2 0.00621061
STOM stomatin 0.00620659
SLC38A10 solute carrier family 38, member 10 0.00620429
FBN2 fibrillin 2 0.00614943
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00614472
APOD apolipoprotein D 0.0060994
NAV2 neuron navigator 2 0.00609625
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.00608825
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00608635
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00604185
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00599964
GSAP gamma-secretase activating protein 0.00598756
SOCS1 suppressor of cytokine signaling 1 0.00597365
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00595598
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.00594458
CTBP2 C-terminal binding protein 2 0.00588556
GPX3 glutathione peroxidase 3 0.00587724
S100A4 S100 calcium binding protein A4 0.00582218
DMTN dematin actin binding protein 0.00581642
AKAP1 A kinase (PRKA) anchor protein 1 0.00579107
IL7R interleukin 7 receptor 0.00577337
CCL5 chemokine (C-C motif) ligand 5 0.00577138
UPK1B uroplakin 1B 0.00577006
FAM46C family with sequence similarity 46, member C 0.00575322
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00574119
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.00573846
CYBB cytochrome b-245, beta polypeptide 0.00571965
TACC2 transforming, acidic coiled-coil containing protein 2 0.00571947
ZBTB38 zinc finger and BTB domain containing 38 0.00571123
PDGFC platelet derived growth factor C 0.00570029
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00569006
KIAA0930 KIAA0930 0.00565113
ORC1 origin recognition complex, subunit 1 0.00564934
PTK2B protein tyrosine kinase 2 beta 0.00563915
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00563231
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.00562252
FAM13A family with sequence similarity 13, member A 0.00561383
FAM193B family with sequence similarity 193, member B 0.00557199
PTK2 protein tyrosine kinase 2 0.00556304
PILRB paired immunoglobin-like type 2 receptor beta 0.00555821
VEGFC vascular endothelial growth factor C 0.00555536
TPSAB1 tryptase alpha/beta 1 0.00555093
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 0.00554962
F5 coagulation factor V (proaccelerin, labile factor) 0.00554091
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00553601
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.00551085
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00550758
SDC1 syndecan 1 0.00548228
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00547627
COL4A6 collagen, type IV, alpha 6 0.00546242
GEM GTP binding protein overexpressed in skeletal muscle 0.00546222
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00546099
PLPP3 phospholipid phosphatase 3 0.005445
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 0.00544364
PNMA8A PNMA family member 8A 0.00544108
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.00543923
HGD homogentisate 1,2-dioxygenase 0.00543743
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00541104
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.00539608
LGALS2 lectin, galactoside-binding, soluble, 2 0.0053947
SMG7 SMG7 nonsense mediated mRNA decay factor 0.00539304
TNC tenascin C 0.00539046
RAB3B RAB3B, member RAS oncogene family 0.00538839
LAMA3 laminin, alpha 3 0.00537833
NBEA neurobeachin 0.00537124
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00535681
AZU1 azurocidin 1 0.00535425
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00534211
SIDT2 SID1 transmembrane family, member 2 0.00533946
CRYBG1 crystallin beta-gamma domain containing 1 0.0053257
TJP2 tight junction protein 2 0.00532191
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00530964
GDI1 GDP dissociation inhibitor 1 0.00530556
RHOB ras homolog family member B 0.00529212
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00528451
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 0.00528364
SORBS2 sorbin and SH3 domain containing 2 0.00526676
ACADVL acyl-CoA dehydrogenase, very long chain 0.00526073
CRYM crystallin, mu 0.00525697
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.00524928
MORC2 MORC family CW-type zinc finger 2 0.00524471
AGTR1 angiotensin II receptor, type 1 0.00524468
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.00524137
RIN2 Ras and Rab interactor 2 0.00524064
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00522106
LONP1 lon peptidase 1, mitochondrial 0.00520852
BIRC3 baculoviral IAP repeat containing 3 0.00520198
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.00517341
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00517088
ADGRL2 adhesion G protein-coupled receptor L2 0.00515206
IL32 interleukin 32 0.0051461
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.00514445
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.00513742
CAV1 caveolin 1, caveolae protein, 22kDa 0.00513422
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00513102
IL2RG interleukin 2 receptor, gamma 0.00512831
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.00512829
JAG1 jagged 1 0.00512811
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.00509993
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0050973
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00509117
IGSF1 immunoglobulin superfamily, member 1 0.00508661
MYOF myoferlin 0.00507641
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00507623
DGKD diacylglycerol kinase, delta 130kDa 0.00505799
TLK2 tousled-like kinase 2 0.00504547
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00502529
TXNIP thioredoxin interacting protein 0.005024
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0049969
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.00499151
SRRM2 serine/arginine repetitive matrix 2 0.00498674
RFC3 replication factor C (activator 1) 3, 38kDa 0.00498232
ADCY9 adenylate cyclase 9 0.00498149
RBPMS RNA binding protein with multiple splicing 0.00497706
RABEP2 rabaptin, RAB GTPase binding effector protein 2 0.0049673
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 0.00493778
HSPB8 heat shock 22kDa protein 8 0.00492054
ZBTB16 zinc finger and BTB domain containing 16 0.00492033
AOX1 aldehyde oxidase 1 0.00490843
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.00490552
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0049051
C10ORF10 chromosome 10 open reading frame 10 0.00490369
ARMCX1 armadillo repeat containing, X-linked 1 0.0049035
KAT2B K(lysine) acetyltransferase 2B 0.00489502
AGRN agrin 0.00489225
NXN nucleoredoxin 0.00488825
MTMR1 myotubularin related protein 1 0.00488486
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00488291
TBX3 T-box 3 0.00488291
IGFBP5 insulin-like growth factor binding protein 5 0.004881
RNASE3 ribonuclease, RNase A family, 3 0.00488024
RTN1 reticulon 1 0.00487167
CAV2 caveolin 2 0.00486959
ILF3 interleukin enhancer binding factor 3, 90kDa 0.00486736
MAGED1 melanoma antigen family D1 0.00485374
SRRM1 serine/arginine repetitive matrix 1 0.0048468
EXOC7 exocyst complex component 7 0.00482617
PROCR protein C receptor, endothelial 0.00482593
IDO1 indoleamine 2,3-dioxygenase 1 0.00482365
CCR2 chemokine (C-C motif) receptor 2 0.00481698
CADPS2 Ca++-dependent secretion activator 2 0.00481664
PYGB phosphorylase, glycogen; brain 0.00478774
WASHC4 WASH complex subunit 4 0.00478521
SHROOM2 shroom family member 2 0.00477529
HDAC9 histone deacetylase 9 0.00477284
EMX2 empty spiracles homeobox 2 0.00477011
DMXL2 Dmx-like 2 0.00476555
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00475737
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00475312

decreased expression

Symbol Name Standardized Value
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0157234
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0150056
EGR2 early growth response 2 -0.0149167
SIRT3 sirtuin 3 -0.0133262
TSPAN8 tetraspanin 8 -0.0104079
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0102939
GPM6B glycoprotein M6B -0.0101197
DSP desmoplakin -0.0100725
MSX1 msh homeobox 1 -0.00969803
COMP cartilage oligomeric matrix protein -0.00960458
FABP7 fatty acid binding protein 7, brain -0.00941596
POSTN periostin, osteoblast specific factor -0.00932501
CLTB clathrin, light chain B -0.00923149
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00907434
TYRP1 tyrosinase-related protein 1 -0.00902294
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00891253
NRBF2 nuclear receptor binding factor 2 -0.00880214
KRT19 keratin 19, type I -0.00878142
CLEC2B C-type lectin domain family 2, member B -0.00877906
INHBA inhibin, beta A -0.00865266
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -0.00848929
S100A10 S100 calcium binding protein A10 -0.0084257
KRT5 keratin 5, type II -0.00842074
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00836551
IFITM3 interferon induced transmembrane protein 3 -0.00828179
MXRA5 matrix-remodelling associated 5 -0.0081939
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00818208
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00813774
TXN thioredoxin -0.00811888
IFITM2 interferon induced transmembrane protein 2 -0.00803446
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00801441
PMP2 peripheral myelin protein 2 -0.00792896
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00790579
S100A7 S100 calcium binding protein A7 -0.00783505
COL11A1 collagen, type XI, alpha 1 -0.00780225
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00780201
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00769746
FRZB frizzled-related protein -0.00769543
MAGEA3 melanoma antigen family A3 -0.00766312
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00763785
HOPX HOP homeobox -0.00757912
PODXL podocalyxin-like -0.00757208
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00756921
TMEM70 transmembrane protein 70 -0.00756097
IFITM1 interferon induced transmembrane protein 1 -0.00749985
NSG1 neuron specific gene family member 1 -0.00747591
ELOC elongin C -0.00746844
LAPTM4B lysosomal protein transmembrane 4 beta -0.00746657
GSTT1 glutathione S-transferase theta 1 -0.00745101
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.0074349
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.00735282
CHMP1B charged multivesicular body protein 1B -0.00733919
DSG1 desmoglein 1 -0.0073387
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00727031
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00722666
BZW1 basic leucine zipper and W2 domains 1 -0.00721558
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00721184
CRIP1 cysteine-rich protein 1 (intestinal) -0.00715901
GAS2 growth arrest-specific 2 -0.00712792
MLF1 myeloid leukemia factor 1 -0.00712046
CCDC90B coiled-coil domain containing 90B -0.00710929
PLP1 proteolipid protein 1 -0.00703365
RCAN1 regulator of calcineurin 1 -0.00699096
DUSP2 dual specificity phosphatase 2 -0.00696823
CST1 cystatin SN -0.00695681
CYTIP cytohesin 1 interacting protein -0.00693333
LY6D lymphocyte antigen 6 complex, locus D -0.00691964
CD59 CD59 molecule, complement regulatory protein -0.00689878
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00687681
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00685234
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.0068186
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00678431
SKAP2 src kinase associated phosphoprotein 2 -0.00677693
MRPS30 mitochondrial ribosomal protein S30 -0.00672702
EGR3 early growth response 3 -0.00669311
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00668807
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00665407
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00663316
RUNX3 runt-related transcription factor 3 -0.00661298
MSMO1 methylsterol monooxygenase 1 -0.00658389
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00656887
C11ORF58 chromosome 11 open reading frame 58 -0.00656847
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -0.00655905
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00654896
SST somatostatin -0.00652241
PEX2 peroxisomal biogenesis factor 2 -0.00651522
S100B S100 calcium binding protein B -0.00647225
ZNF165 zinc finger protein 165 -0.00644961
INHBB inhibin, beta B -0.00644812
CAPRIN1 cell cycle associated protein 1 -0.00643705
EDNRB endothelin receptor type B -0.00638883
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00634668
OSTF1 osteoclast stimulating factor 1 -0.00632908
MEX3C mex-3 RNA binding family member C -0.00628679
COL3A1 collagen, type III, alpha 1 -0.00624025
ITPRID2 ITPR interacting domain containing 2 -0.00623168
THBS2 thrombospondin 2 -0.00622375
TRIM36 tripartite motif containing 36 -0.0062231
TOX thymocyte selection-associated high mobility group box -0.00615328
KLF6 Kruppel-like factor 6 -0.00612953
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.00612795
ABHD3 abhydrolase domain containing 3 -0.00611629
SFRP4 secreted frizzled-related protein 4 -0.00610629
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00609021
METRN meteorin, glial cell differentiation regulator -0.00608113
LDHA lactate dehydrogenase A -0.00607431
ATP5F1E ATP synthase F1 subunit epsilon -0.00603796
S100A2 S100 calcium binding protein A2 -0.00603315
SLPI secretory leukocyte peptidase inhibitor -0.00603095
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00601283
CALCA calcitonin-related polypeptide alpha -0.00598738
ENO1 enolase 1, (alpha) -0.00598144
KRT14 keratin 14, type I -0.00597129
GOLPH3 golgi phosphoprotein 3 (coat-protein) -0.00593527
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0059311
TUBB2B tubulin, beta 2B class IIb -0.00590851
BHLHE41 basic helix-loop-helix family, member e41 -0.00589776
LY96 lymphocyte antigen 96 -0.00589767
NXT2 nuclear transport factor 2-like export factor 2 -0.00588421
RGCC regulator of cell cycle -0.00588092
CHMP2B charged multivesicular body protein 2B -0.00586654
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00584501
EFNA1 ephrin-A1 -0.0058353
FBXO2 F-box protein 2 -0.00582553
DMAC2L distal membrane arm assembly component 2 like -0.00575777
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00574781
MOB4 MOB family member 4, phocein -0.00572101
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00571486
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00570996
PPA1 pyrophosphatase (inorganic) 1 -0.00568583
MCAM melanoma cell adhesion molecule -0.00568095
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.0056586
REEP5 receptor accessory protein 5 -0.0056239
TNNC1 troponin C type 1 (slow) -0.00561412
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.00560492
MBIP MAP3K12 binding inhibitory protein 1 -0.00560395
RAB9A RAB9A, member RAS oncogene family -0.00560146
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00559023
MRPL19 mitochondrial ribosomal protein L19 -0.00558987
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00558358
CRABP2 cellular retinoic acid binding protein 2 -0.00558217
COMMD8 COMM domain containing 8 -0.00558014
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00557853
SH3BGR SH3 domain binding glutamate-rich protein -0.00552344
RAB25 RAB25, member RAS oncogene family -0.00551996
F2R coagulation factor II (thrombin) receptor -0.00549394
EMC2 ER membrane protein complex subunit 2 -0.00549376
KRT17 keratin 17, type I -0.00548299
PDGFD platelet derived growth factor D -0.00548145
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -0.00543465
SEPP1 selenoprotein P, plasma, 1 -0.00543256
TPBG trophoblast glycoprotein -0.00541512
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00540822
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00540348
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00540262
PPID peptidylprolyl isomerase D -0.00539441
CRABP1 cellular retinoic acid binding protein 1 -0.00539055
MYL12B myosin, light chain 12B, regulatory -0.00538602
THY1 Thy-1 cell surface antigen -0.00535138
BGN biglycan -0.00535096
CGA glycoprotein hormones, alpha polypeptide -0.00534583
MAGEA12 melanoma antigen family A12 -0.00534054
TTYH1 tweety family member 1 -0.00533314
CREM cAMP responsive element modulator -0.00528676
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.00528473
MB myoglobin -0.00528382
SLC16A6 solute carrier family 16, member 6 -0.00528346
MED28 mediator complex subunit 28 -0.00527243
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00525424
GPX7 glutathione peroxidase 7 -0.0052525
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -0.00524886
NDN necdin, melanoma antigen (MAGE) family member -0.00524496
MDK midkine (neurite growth-promoting factor 2) -0.00524232
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00523663
IGFBP6 insulin-like growth factor binding protein 6 -0.00522241
TCTA T-cell leukemia translocation altered -0.00521929
HEPH hephaestin -0.00519688
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00517039
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00516058
TM4SF1 transmembrane 4 L six family member 1 -0.00515825
CGRRF1 cell growth regulator with ring finger domain 1 -0.00515699
CRYZ crystallin, zeta (quinone reductase) -0.00512189
CNR1 cannabinoid receptor 1 (brain) -0.00512139
HSPA2 heat shock 70kDa protein 2 -0.00511507
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00510986
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00510249
KLK5 kallikrein-related peptidase 5 -0.00510221
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00509879
ASS1 argininosuccinate synthase 1 -0.00509759
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.0050726
APC adenomatous polyposis coli -0.00506525
TPD52 tumor protein D52 -0.00505295
RAB4A RAB4A, member RAS oncogene family -0.00505136
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00504871
DYNLL1 dynein, light chain, LC8-type 1 -0.00504466
GOLT1B golgi transport 1B -0.00503956
GPM6A glycoprotein M6A -0.00503521
BAALC brain and acute leukemia, cytoplasmic -0.00503488
CH25H cholesterol 25-hydroxylase -0.00502838
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00502373
CALCRL calcitonin receptor-like -0.00502065
MTERF3 mitochondrial transcription termination factor 3 -0.00502062
SOWAHC sosondowah ankyrin repeat domain family member C -0.00501922
CLDN7 claudin 7 -0.00497603
COL10A1 collagen, type X, alpha 1 -0.00497602
FGFR1 fibroblast growth factor receptor 1 -0.0049756
TM6SF1 transmembrane 6 superfamily member 1 -0.00496128
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00495558
TMEM14A transmembrane protein 14A -0.00495343
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.0049502
RHOA ras homolog family member A -0.00493559
TMEM45A transmembrane protein 45A -0.0049283
ZNF226 zinc finger protein 226 -0.00492144
SS18 synovial sarcoma translocation, chromosome 18 -0.00491965
IL1R2 interleukin 1 receptor, type II -0.00491959
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00490971
TSPAN13 tetraspanin 13 -0.00490927
CYRIB CYFIP related Rac1 interactor B -0.00490275
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00490134
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00489833
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00489125
SCRG1 stimulator of chondrogenesis 1 -0.00488842
TAC1 tachykinin, precursor 1 -0.00487287
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0048698
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.004859
YIPF5 Yip1 domain family, member 5 -0.00485479
FSTL1 follistatin-like 1 -0.00485187
SLIRP SRA stem-loop interacting RNA binding protein -0.00485158
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00484807
COX17 COX17 cytochrome c oxidase copper chaperone -0.00484511
NUTF2 nuclear transport factor 2 -0.00484215
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.00483561
GPR137B G protein-coupled receptor 137B -0.00483465
STAT5B signal transducer and activator of transcription 5B -0.00482786
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00482658
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00482322
E2F5 E2F transcription factor 5, p130-binding -0.00482269
AKIRIN1 akirin 1 -0.00481646
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0048062
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.00480615
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00479424
ZG16 zymogen granule protein 16 -0.00478422
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00478318
OLFML3 olfactomedin-like 3 -0.00477806
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00477409
SEPTIN11 septin 11 -0.0047616
HSPB11 heat shock protein family B (small), member 11 -0.00475973
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00475639