SUOX Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description sulfite oxidase|Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6821)
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Genes

349 genes differentially expressed following the SUOX gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FOXQ1 forkhead box Q1 3.51534
RUNDC3B RUN domain containing 3B 3.51534
KRTAP21-1 keratin associated protein 21-1 3.51534
OSR2 odd-skipped related transciption factor 2 3.51534
CXORF65 chromosome X open reading frame 65 3.51534
FOXR1 forkhead box R1 3.51534
ARHGAP36 Rho GTPase activating protein 36 3.51534
PLCH2 phospholipase C, eta 2 3.51534
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 3.51534
CEP19 centrosomal protein 19kDa 3.51534
PGBDF plakoglobin binding and degradation factor 3.51534
AKR1C2 aldo-keto reductase family 1, member C2 3.51534
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 3.51534
CHADL chondroadherin-like 3.51534
FGD2 FYVE, RhoGEF and PH domain containing 2 3.51534
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 3.51534
SCG2 secretogranin II 3.51534
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.51534
NPPB natriuretic peptide B 3.51534
SCN2B sodium channel, voltage gated, type II beta subunit 3.51534
ANKRD22 ankyrin repeat domain 22 3.51534
SP7 Sp7 transcription factor 3.51534
OTUD6A OTU deubiquitinase 6A 3.51534
CRYGB crystallin, gamma B 3.51534
CRYGN crystallin, gamma N 3.51534
BHMT2 betaine--homocysteine S-methyltransferase 2 3.51534
TAS2R19 taste receptor, type 2, member 19 3.51534
TSHZ1 teashirt zinc finger homeobox 1 3.51534
LDHC lactate dehydrogenase C 3.51534
TPPP tubulin polymerization promoting protein 3.51534
FGF8 fibroblast growth factor 8 (androgen-induced) 3.51534
CCDC87 coiled-coil domain containing 87 3.51534
LRRC61 leucine rich repeat containing 61 3.51534
GNRH2 gonadotropin-releasing hormone 2 3.51534
F7 coagulation factor VII (serum prothrombin conversion accelerator) 3.51534
GMFG glia maturation factor, gamma 3.51534
LRRC10B leucine rich repeat containing 10B 3.51534
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.51534
CRH corticotropin releasing hormone 3.51534
CPB1 carboxypeptidase B1 (tissue) 3.51534
TMEM89 transmembrane protein 89 3.51534
OC90 otoconin 90 3.51534
LGI1 leucine-rich, glioma inactivated 1 3.51534
RNASE6 ribonuclease, RNase A family, k6 3.51534
TMEM276-ZFTRAF1 TMEM276-ZFTRAF1 readthrough 3.51534
CAPN9 calpain 9 3.51534
SPRR2F small proline-rich protein 2F 3.51534
PLCZ1 phospholipase C, zeta 1 3.51534
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 3.51534
OR1C1 olfactory receptor, family 1, subfamily C, member 1 3.51534
BDKRB1 bradykinin receptor B1 3.51534
FCMR Fc fragment of IgM receptor 3.51534
POU2F3 POU class 2 homeobox 3 3.51534
GPR85 G protein-coupled receptor 85 3.51534
TYROBP TYRO protein tyrosine kinase binding protein 3.51534
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 3.51534
SPMIP11 sperm microtubule inner protein 11 3.51534
NOTCH2NLB notch 2 N-terminal like B 3.51534
C17ORF113 chromosome 17 open reading frame 113 3.51534
H4C12 H4 clustered histone 12 3.51534
H3C3 H3 clustered histone 3 3.51534
ARMH2 armadillo like helical domain containing 2 3.51534
CHCT1 CHD1 helical C-terminal domain containing 1 3.51534
PLAAT4 phospholipase A and acyltransferase 4 3.51534
HTD2 hydroxyacyl-thioester dehydratase type 2 3.51534
VCX3B variable charge, X-linked 3B 3.51534
BARX1 BARX homeobox 1 3.51534
THPO thrombopoietin 3.51534
WNT11 wingless-type MMTV integration site family, member 11 3.51534
AMBP alpha-1-microglobulin/bikunin precursor 3.51534
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.51534
ITK IL2-inducible T-cell kinase 3.51534
CLDN2 claudin 2 3.51534
TLE6 transducin-like enhancer of split 6 3.51534
RAB41 RAB41, member RAS oncogene family 3.51534
ACOT1 acyl-CoA thioesterase 1 3.51534
C3ORF80 chromosome 3 open reading frame 80 3.51534
SCN10A sodium channel, voltage gated, type X alpha subunit 3.51534
PRR4 proline rich 4 (lacrimal) 3.51534
NPFF neuropeptide FF-amide peptide precursor 3.51534
CREB3L3 cAMP responsive element binding protein 3-like 3 3.51534
C1QTNF1 C1q and tumor necrosis factor related protein 1 3.51534
BHLHA9 basic helix-loop-helix family, member a9 3.51534
IL5 interleukin 5 3.51534
DNASE2B deoxyribonuclease II beta 3.51534
ANXA10 annexin A10 3.51534
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 3.51534
TPBGL trophoblast glycoprotein-like 3.51534
F11 coagulation factor XI 3.51534
LMOD3 leiomodin 3 (fetal) 3.51534
ISL1 ISL LIM homeobox 1 3.51534
OR8H1 olfactory receptor, family 8, subfamily H, member 1 3.51534
CER1 cerberus 1, DAN family BMP antagonist 3.51534
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 3.51534
PRDM9 PR domain containing 9 3.51534
CFAP47 cilia and flagella associated protein 47 3.51534
ZC3H12D zinc finger CCCH-type containing 12D 3.51534
AGR2 anterior gradient 2 3.51534
TRIM29 tripartite motif containing 29 3.51534
RASL11A RAS-like, family 11, member A 3.51534
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.51534
ALOX15B arachidonate 15-lipoxygenase, type B 3.51534
NGFR nerve growth factor receptor 3.51534
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 3.51534
PCDHGA7 protocadherin gamma subfamily A, 7 3.51534
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 3.51534
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 3.51534
NOX1 NADPH oxidase 1 3.51534
ARR3 arrestin 3, retinal (X-arrestin) 3.51534
POF1B premature ovarian failure, 1B 3.51534
C16ORF78 chromosome 16 open reading frame 78 3.51534
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 3.51534
MRLN myoregulin 3.51534
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.51534
KCNK9 potassium channel, two pore domain subfamily K, member 9 3.51534
NACA2 nascent polypeptide-associated complex alpha subunit 2 3.51534
MAB21L3 mab-21-like 3 (C. elegans) 3.51534
CGB7 chorionic gonadotropin, beta polypeptide 7 3.51534
CARNS1 carnosine synthase 1 3.51534
TPPP3 tubulin polymerization-promoting protein family member 3 3.51534
LYZL1 lysozyme-like 1 3.51534
OTP orthopedia homeobox 3.51534
FRMPD2 FERM and PDZ domain containing 2 3.51534
ETV3L ets variant 3-like 3.51534
SPDYE2B speedy/RINGO cell cycle regulator family member E2B 3.51534
PDYN prodynorphin 3.51534
ZNF648 zinc finger protein 648 3.51534
NLRP6 NLR family, pyrin domain containing 6 3.51534
EVI2A ecotropic viral integration site 2A 3.51534
GJC2 gap junction protein, gamma 2, 47kDa 3.51534
TMEM52B transmembrane protein 52B 3.51534
NRSN1 neurensin 1 3.51534
ITGAD integrin, alpha D 3.51534
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 3.51534
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.51534
TYR tyrosinase 3.51534
CLEC9A C-type lectin domain family 9, member A 3.51534
VAV1 vav 1 guanine nucleotide exchange factor 3.51534
FBN1 fibrillin 1 3.51534
CHRM1 cholinergic receptor, muscarinic 1 3.51534
SLC38A3 solute carrier family 38, member 3 3.51534
RERGL RERG/RAS-like 3.51534
PFN4 profilin family, member 4 3.51534
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.51534
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.51534
CD8A CD8a molecule 3.51534
ADGRF5 adhesion G protein-coupled receptor F5 3.51534
SNX31 sorting nexin 31 3.39949
MCOLN2 mucolipin 2 3.02756
SBK2 SH3 domain binding kinase family, member 2 2.88499
ADPRH ADP-ribosylarginine hydrolase 2.88499
MATCAP1 microtubule associated tyrosine carboxypeptidase 1 2.8758
CCT2 chaperonin containing TCP1, subunit 2 (beta) 2.86017
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 2.84196
VEGFD vascular endothelial growth factor D 2.83523
TBCB tubulin folding cofactor B 2.79954
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) 2.78476
LEMD1 LEM domain containing 1 2.78476
LINC02762 long intergenic non-protein coding RNA 2762 2.76954
PCLO piccolo presynaptic cytomatrix protein 2.59933
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 2.58648
CREM cAMP responsive element modulator 2.57361
ZNF84 zinc finger protein 84 2.52236
EPHX3 epoxide hydrolase 3 2.49482
FYN FYN proto-oncogene, Src family tyrosine kinase 2.47273
DAZAP1 DAZ associated protein 1 2.46463
RUFY4 RUN and FYVE domain containing 4 2.46463
ACP4 acid phosphatase 4 2.46463
DEFB131B defensin beta 131B 2.46463
NELL1 NEL-like 1 (chicken) 2.46463
DAND5 DAN domain family member 5, BMP antagonist 2.46463
RHCE Rh blood group, CcEe antigens 2.46463
CBLIF cobalamin binding intrinsic factor 2.46463
ALAS2 5'-aminolevulinate synthase 2 2.46463
SCRN2 secernin 2 2.45311
MAGEB17 melanoma antigen family B17 2.42041
FSHR follicle stimulating hormone receptor 2.42041
MMP21 matrix metallopeptidase 21 2.42041
NXPH2 neurexophilin 2 2.42041
TRIM73 tripartite motif containing 73 2.42041
EFHB EF-hand domain family, member B 2.42041
PLA2G10 phospholipase A2, group X 2.42041
PIRT phosphoinositide-interacting regulator of transient receptor potential channels 2.42041
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.40444
SLMAP sarcolemma associated protein 2.38205
TUBA1B tubulin, alpha 1b 2.38205
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) 2.36521
TMEM177 transmembrane protein 177 2.34592
ZFTA zinc finger translocation associated 2.34421
CNTNAP5 contactin associated protein-like 5 2.32093
NUBP2 nucleotide binding protein 2 2.31061
C5ORF34 chromosome 5 open reading frame 34 2.30601
NXNL1 nucleoredoxin-like 1 2.27314
IGFBP7 insulin-like growth factor binding protein 7 2.27314
TMEM86A transmembrane protein 86A 2.27314
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.26046
KCTD13 potassium channel tetramerization domain containing 13 2.22759
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 2.22333
PRMT5 protein arginine methyltransferase 5 2.21831
PIANP PILR alpha associated neural protein 2.2085
IK IK cytokine, down-regulator of HLA II 2.16918
TCOF1 Treacher Collins-Franceschetti syndrome 1 2.12585
EBP emopamil binding protein (sterol isomerase) 2.09275
MSL1 male-specific lethal 1 homolog (Drosophila) 2.08487
MROH8 maestro heat-like repeat family member 8 2.08143
SLC35F4 solute carrier family 35, member F4 2.07906
KLHL25 kelch-like family member 25 2.07035
HSPA4 heat shock 70kDa protein 4 2.0602
CALM1 calmodulin 1 (phosphorylase kinase, delta) 2.05704
MGMT O-6-methylguanine-DNA methyltransferase 2.05428
TMEM167A transmembrane protein 167A 2.05428
SLC71A2 solute carrier family 71 member 2 2.05428
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 2.04958
PTBP3 polypyrimidine tract binding protein 3 2.01829

decreased expression

Symbol Name Standardized Value
BRICD5 BRICHOS domain containing 5 -3.51534
TMIGD3 transmembrane and immunoglobulin domain containing 3 -3.51534
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -3.51534
PIH1D2 PIH1 domain containing 2 -3.51534
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -3.51534
TIGD3 tigger transposable element derived 3 -3.51534
SUMO4 small ubiquitin-like modifier 4 -3.51534
F2RL2 coagulation factor II (thrombin) receptor-like 2 -3.51534
SH2D4B SH2 domain containing 4B -3.51534
PCDHGA5 protocadherin gamma subfamily A, 5 -3.51534
XK X-linked Kx blood group -3.51534
CD7 CD7 molecule -3.51534
ADM5 adrenomedullin 5 (putative) -3.51534
ZBED6 zinc finger, BED-type containing 6 -3.51534
SPX spexin hormone -3.51534
KIAA2012 KIAA2012 -3.51534
IL18R1 interleukin 18 receptor 1 -3.51534
SLC10A4 solute carrier family 10, member 4 -3.51534
TMEM217 transmembrane protein 217 -3.51534
FGF6 fibroblast growth factor 6 -3.51534
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) -3.51534
HEPHL1 hephaestin-like 1 -3.51534
PADI1 peptidyl arginine deiminase, type I -3.51534
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 -3.51534
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -3.51534
IL1A interleukin 1, alpha -3.51534
DUSP2 dual specificity phosphatase 2 -3.51534
MAP6 microtubule-associated protein 6 -3.51534
VSTM1 V-set and transmembrane domain containing 1 -3.51534
VMO1 vitelline membrane outer layer 1 homolog (chicken) -3.51534
YIPF7 Yip1 domain family, member 7 -3.51534
TENT5D terminal nucleotidyltransferase 5D -3.51534
PLAC8 placenta-specific 8 -3.51534
INSM1 insulinoma-associated 1 -3.51534
IDI2 isopentenyl-diphosphate delta isomerase 2 -3.51534
DEFB109B defensin beta 109B -3.51534
LYPD5 LY6/PLAUR domain containing 5 -3.51534
DCDC2B doublecortin domain containing 2B -3.51534
KCTD21 potassium channel tetramerization domain containing 21 -3.51534
CCDC177 coiled-coil domain containing 177 -3.51534
MOK MOK protein kinase -3.51534
CD79B CD79b molecule, immunoglobulin-associated beta -3.46192
NOS3 nitric oxide synthase 3 (endothelial cell) -3.46192
SPIN3 spindlin family, member 3 -3.39937
ZNF688 zinc finger protein 688 -3.28329
ARF1 ADP-ribosylation factor 1 -3.15598
TMEM74B transmembrane protein 74B -3.09693
CSPP1 centrosome and spindle pole associated protein 1 -3.08018
DPYS dihydropyrimidinase -3.02447
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.94387
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -2.90394
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -2.88637
ZNF732 zinc finger protein 732 -2.85907
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 -2.85667
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.83523
PSKH1 protein serine kinase H1 -2.82651
PRSS8 protease, serine, 8 -2.69532
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -2.69532
CC2D1A coiled-coil and C2 domain containing 1A -2.67511
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -2.67286
SPDYE10 speedy/RINGO cell cycle regulator family member E10 -2.67076
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -2.64692
AHSP alpha hemoglobin stabilizing protein -2.62515
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -2.6089
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.58353
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 -2.56928
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -2.56321
YIPF3 Yip1 domain family, member 3 -2.55762
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -2.54465
B9D1 B9 protein domain 1 -2.54251
MINAR1 membrane integral NOTCH2 associated receptor 1 -2.49482
IGSF3 immunoglobulin superfamily, member 3 -2.48475
MFSD11 major facilitator superfamily domain containing 11 -2.47273
H4C2 H4 clustered histone 2 -2.46745
SLC25A43 solute carrier family 25, member 43 -2.46463
CD86 CD86 molecule -2.46463
FNDC3B fibronectin type III domain containing 3B -2.46463
FXYD3 FXYD domain containing ion transport regulator 3 -2.46463
CCDC81 coiled-coil domain containing 81 -2.46463
TLE4 transducin-like enhancer of split 4 -2.46463
CRTAC1 cartilage acidic protein 1 -2.46463
GARIN2 golgi associated RAB2 interactor family member 2 -2.39886
ZNF343 zinc finger protein 343 -2.39886
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -2.39886
SLC44A4 solute carrier family 44, member 4 -2.39886
IGSF10 immunoglobulin superfamily, member 10 -2.39886
MTARC1 mitochondrial amidoxime reducing component 1 -2.39597
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.39397
PAIP1 poly(A) binding protein interacting protein 1 -2.37753
DERL3 derlin 3 -2.37463
ZNF317 zinc finger protein 317 -2.36514
CSRNP3 cysteine-serine-rich nuclear protein 3 -2.36514
MISP3 MISP family member 3 -2.36514
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta -2.36514
CACHD1 cache domain containing 1 -2.35176
PEX11A peroxisomal biogenesis factor 11 alpha -2.32287
ZNG1B Zn regulated GTPase metalloprotein activator 1B -2.31033
ZNF253 zinc finger protein 253 -2.30365
FBXL19 F-box and leucine-rich repeat protein 19 -2.3022
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.3022
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) -2.28884
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.28148
BHMT betaine--homocysteine S-methyltransferase -2.28148
C16ORF54 chromosome 16 open reading frame 54 -2.28148
ZBTB11 zinc finger and BTB domain containing 11 -2.27065
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -2.27065
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.26217
TSEN15 TSEN15 tRNA splicing endonuclease subunit -2.25693
UFSP2 UFM1-specific peptidase 2 -2.24689
ZDHHC1 zinc finger, DHHC-type containing 1 -2.24058
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -2.21549
FRMD3 FERM domain containing 3 -2.21093
METTL15 methyltransferase like 15 -2.21093
DAD1 defender against cell death 1 -2.18432
TCTN1 tectonic family member 1 -2.18256
RECQL4 RecQ protein-like 4 -2.17643
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.17625
NRDE2 NRDE-2, necessary for RNA interference, domain containing -2.16918
COPRS coordinator of PRMT5, differentiation stimulator -2.16918
ZNF543 zinc finger protein 543 -2.16266
ZNF334 zinc finger protein 334 -2.13134
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -2.12184
WWC2 WW and C2 domain containing 2 -2.12184
NDC1 NDC1 transmembrane nucleoporin -2.10475
AMOTL1 angiomotin like 1 -2.09536
ENTREP3 endosomal transmembrane epsin interactor 3 -2.0834
NPC1 Niemann-Pick disease, type C1 -2.07035
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 -2.06955
GCDH glutaryl-CoA dehydrogenase -2.06955
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.05153
NCOA4 nuclear receptor coactivator 4 -2.01829
CCDC51 coiled-coil domain containing 51 -2.0169
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled -2.00181
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.00065
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.00065