SUP-M2 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human anaplastic large cell lymphoma (ALCL) cell line; derived from the cerebrospinal fluid of a 5-year-old girl with refractory malignant histiocytosis. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004775)
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320 genes mutated in the SUP-M2 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ADAM29 ADAM metallopeptidase domain 29
ADRA1A adrenoceptor alpha 1A
AFF2 AF4/FMR2 family, member 2
AHNAK2 AHNAK nucleoprotein 2
AKAP11 A kinase (PRKA) anchor protein 11
AKAP4 A kinase (PRKA) anchor protein 4
AKAP9 A kinase (PRKA) anchor protein 9
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALK anaplastic lymphoma receptor tyrosine kinase
AMT aminomethyltransferase
ANK2 ankyrin 2, neuronal
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD18B ankyrin repeat domain 18B
ANKRD23 ankyrin repeat domain 23
ANLN anillin, actin binding protein
AOC2 amine oxidase, copper containing 2 (retina-specific)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APCDD1L adenomatosis polyposis coli down-regulated 1-like
APP amyloid beta (A4) precursor protein
ARHGAP10 Rho GTPase activating protein 10
ARHGAP32 Rho GTPase activating protein 32
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL16 ADP-ribosylation factor-like 16
ARMCX4 armadillo repeat containing, X-linked 4
ART1 ADP-ribosyltransferase 1
ATM ATM serine/threonine kinase
ATOH1 atonal homolog 1 (Drosophila)
ATP13A5 ATPase type 13A5
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATRNL1 attractin-like 1
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BEGAIN brain-enriched guanylate kinase-associated
BMP15 bone morphogenetic protein 15
BRI3 brain protein I3
BZW1 basic leucine zipper and W2 domains 1
CACFD1 calcium channel flower domain containing 1
CARS cysteinyl-tRNA synthetase
CAT catalase
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC39 coiled-coil domain containing 39
CCDC74A coiled-coil domain containing 74A
CCDC82 coiled-coil domain containing 82
CCHCR1 coiled-coil alpha-helical rod protein 1
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CD5 CD5 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDAN1 codanin 1
CDC16 cell division cycle 16
CDC23 cell division cycle 23
CDCA8 cell division cycle associated 8
CDCP2 CUB domain containing protein 2
CDH23 cadherin-related 23
CEP170B centrosomal protein 170B
CEP72 centrosomal protein 72kDa
CEP85 centrosomal protein 85kDa
CEP89 centrosomal protein 89kDa
CFAP46 cilia and flagella associated protein 46
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD7 chromodomain helicase DNA binding protein 7
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLCNKB chloride channel, voltage-sensitive Kb
COL4A5 collagen, type IV, alpha 5
COPA coatomer protein complex, subunit alpha
CPA1 carboxypeptidase A1 (pancreatic)
CPN2 carboxypeptidase N, polypeptide 2
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRCP CGRP receptor component
CSF1 colony stimulating factor 1 (macrophage)
CSMD3 CUB and Sushi multiple domains 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DHH desert hedgehog
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNMBP dynamin binding protein
DSP desmoplakin
DVL3 dishevelled segment polarity protein 3
E2F8 E2F transcription factor 8
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELL elongation factor RNA polymerase II
EP300 E1A binding protein p300
EP400 E1A binding protein p400
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPHA4 EPH receptor A4
EXTL3 exostosin-like glycosyltransferase 3
FAM166B family with sequence similarity 166, member B
FANCA Fanconi anemia, complementation group A
FAT2 FAT atypical cadherin 2
FBXO44 F-box protein 44
FES FES proto-oncogene, tyrosine kinase
FGF1 fibroblast growth factor 1 (acidic)
FILIP1 filamin A interacting protein 1
FLT1 fms-related tyrosine kinase 1
FMOD fibromodulin
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GFM1 G elongation factor, mitochondrial 1
GGT1 gamma-glutamyltransferase 1
GNS glucosamine (N-acetyl)-6-sulfatase
GOLGA8J golgin A8 family, member J
GPBAR1 G protein-coupled bile acid receptor 1
GPC2 glypican 2
GPC4 glypican 4
GPR139 G protein-coupled receptor 139
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIP2 glutamate receptor interacting protein 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HDAC9 histone deacetylase 9
HEATR6 HEAT repeat containing 6
HEPH hephaestin
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIF3A hypoxia inducible factor 3, alpha subunit
HIPK3 homeodomain interacting protein kinase 3
HIST1H2AE histone cluster 1, H2ae
HIST1H2BB histone cluster 1, H2bb
HIST1H2BI histone cluster 1, H2bi
HLA-B major histocompatibility complex, class I, B
HOXB1 homeobox B1
HSPG2 heparan sulfate proteoglycan 2
HYAL2 hyaluronoglucosaminidase 2
IDI2 isopentenyl-diphosphate delta isomerase 2
IGFBP4 insulin-like growth factor binding protein 4
IL16 interleukin 16
IP6K3 inositol hexakisphosphate kinase 3
IRF1 interferon regulatory factor 1
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
KANK3 KN motif and ankyrin repeat domains 3
KAT2A K(lysine) acetyltransferase 2A
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNT2 potassium channel, sodium activated subfamily T, member 2
KDM4C lysine (K)-specific demethylase 4C
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0020 KIAA0020
KIAA0100 KIAA0100
KIAA1407 KIAA1407
KIAA1671 KIAA1671
KIF20B kinesin family member 20B
KIF21B kinesin family member 21B
KIFC1 kinesin family member C1
KMT2D lysine (K)-specific methyltransferase 2D
KRBA1 KRAB-A domain containing 1
KRTAP4-12 keratin associated protein 4-12
KRTAP5-1 keratin associated protein 5-1
KSR1 kinase suppressor of ras 1
LBP lipopolysaccharide binding protein
LCN9 lipocalin 9
LDHAL6B lactate dehydrogenase A-like 6B
LEKR1 leucine, glutamate and lysine rich 1
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LEPROT leptin receptor overlapping transcript
LHFPL1 lipoma HMGIC fusion partner-like 1
LMF1 lipase maturation factor 1
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRRC16B leucine rich repeat containing 16B
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LTBP4 latent transforming growth factor beta binding protein 4
MACC1 metastasis associated in colon cancer 1
MANSC1 MANSC domain containing 1
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAPK6 mitogen-activated protein kinase 6
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAST4 microtubule associated serine/threonine kinase family member 4
MCM9 minichromosome maintenance complex component 9
MDC1 mediator of DNA-damage checkpoint 1
MEP1A meprin A, alpha (PABA peptide hydrolase)
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MICU3 mitochondrial calcium uptake family, member 3
MLPH melanophilin
MRPS5 mitochondrial ribosomal protein S5
MSTO1 misato 1, mitochondrial distribution and morphology regulator
MTMR8 myotubularin related protein 8
MUC19 mucin 19, oligomeric
MYLK myosin light chain kinase
MYO1F myosin IF
MYO5B myosin VB
N4BP2L1 NEDD4 binding protein 2-like 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
NECAB2 N-terminal EF-hand calcium binding protein 2
NELFA negative elongation factor complex member A
NFE2L3 nuclear factor, erythroid 2-like 3
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NISCH nischarin
NOMO1 NODAL modulator 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRG3 neuregulin 3
NT5C1A 5'-nucleotidase, cytosolic IA
NUP62 nucleoporin 62kDa
NXPH4 neurexophilin 4
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OVGP1 oviductal glycoprotein 1, 120kDa
PABPC5 poly(A) binding protein, cytoplasmic 5
PAGE1 P antigen family, member 1 (prostate associated)
PARD3B par-3 family cell polarity regulator beta
PARK2 parkin RBR E3 ubiquitin protein ligase
PGC progastricsin (pepsinogen C)
PHF14 PHD finger protein 14
PHRF1 PHD and ring finger domains 1
PKD1L1 polycystic kidney disease 1 like 1
PKN1 protein kinase N1
PLB1 phospholipase B1
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
PLTP phospholipid transfer protein
PNLIPRP1 pancreatic lipase-related protein 1
PNMAL1 paraneoplastic Ma antigen family-like 1
POGZ pogo transposable element with ZNF domain
POLN polymerase (DNA directed) nu
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PPAN peter pan homolog (Drosophila)
PPAN-P2RY11 PPAN-P2RY11 readthrough
PRB4 proline-rich protein BstNI subfamily 4
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRSS3 protease, serine, 3
PSIP1 PC4 and SFRS1 interacting protein 1
PSRC1 proline/serine-rich coiled-coil 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB20 RAB20, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASA3 RAS p21 protein activator 3
RECQL4 RecQ protein-like 4
RGAG1 retrotransposon gag domain containing 1
RNF181 ring finger protein 181
RNF31 ring finger protein 31
RP1L1 retinitis pigmentosa 1-like 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RXRA retinoid X receptor, alpha
SAGE1 sarcoma antigen 1
SALL4 spalt-like transcription factor 4
SCN2A sodium channel, voltage gated, type II alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SETBP1 SET binding protein 1
SETX senataxin
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
SH2D5 SH2 domain containing 5
SHD Src homology 2 domain containing transforming protein D
SHROOM3 shroom family member 3
SIDT2 SID1 transmembrane family, member 2
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35F3 solute carrier family 35, member F3
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SLIT3 slit homolog 3 (Drosophila)
SLITRK1 SLIT and NTRK-like family, member 1
SORBS2 sorbin and SH3 domain containing 2
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPINK5 serine peptidase inhibitor, Kazal type 5
SSX5 synovial sarcoma, X breakpoint 5
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STIM2 stromal interaction molecule 2
STXBP4 syntaxin binding protein 4
SYNGR2 synaptogyrin 2
SYNJ1 synaptojanin 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TBC1D22A TBC1 domain family, member 22A
TCF4 transcription factor 4
TEX10 testis expressed 10
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLR9 toll-like receptor 9
TM7SF3 transmembrane 7 superfamily member 3
TMEM132C transmembrane protein 132C
TMEM165 transmembrane protein 165
TMEM41B transmembrane protein 41B
TMEM86A transmembrane protein 86A
TNC tenascin C
TOP3A topoisomerase (DNA) III alpha
TRAPPC10 trafficking protein particle complex 10
TSPYL2 TSPY-like 2
TTN titin
TUBB1 tubulin, beta 1 class VI
TUBB4B tubulin, beta 4B class IVb
UBAP1 ubiquitin associated protein 1
UBAP2L ubiquitin associated protein 2-like
UBXN6 UBX domain protein 6
UNC79 unc-79 homolog (C. elegans)
UNC93A unc-93 homolog A (C. elegans)
URGCP upregulator of cell proliferation
USP29 ubiquitin specific peptidase 29
USP31 ubiquitin specific peptidase 31
USP54 ubiquitin specific peptidase 54
UTRN utrophin
VAV2 vav 2 guanine nucleotide exchange factor
VNN1 vanin 1
WDFY4 WDFY family member 4
WDR88 WD repeat domain 88
XKRX XK, Kell blood group complex subunit-related, X-linked
ZCCHC6 zinc finger, CCHC domain containing 6
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF208 zinc finger protein 208
ZNF212 zinc finger protein 212
ZNF451 zinc finger protein 451
ZNF554 zinc finger protein 554
ZNF560 zinc finger protein 560
ZNF597 zinc finger protein 597
ZNF624 zinc finger protein 624
ZNF84 zinc finger protein 84
ZSCAN21 zinc finger and SCAN domain containing 21