SUZ12 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SUZ12 polycomb repressive complex 2 subunit|This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009] (NCBI Entrez Gene Database, 23512)
External Link https://ncbi.nlm.nih.gov/gene/23512
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Genes

499 genes differentially expressed following the SUZ12 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PITX3 paired-like homeodomain 3 0.0111305
CEMIP cell migration inducing protein, hyaluronan binding 0.0104787
TUBB2A tubulin, beta 2A class IIa 0.0102362
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00990004
NT5E 5'-nucleotidase, ecto (CD73) 0.00926094
TM4SF1 transmembrane 4 L six family member 1 0.00921063
THBS1 thrombospondin 1 0.00919797
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00889954
CAST calpastatin 0.00885839
IGFBP5 insulin-like growth factor binding protein 5 0.00853236
IFI6 interferon, alpha-inducible protein 6 0.00824822
BAMBI BMP and activin membrane-bound inhibitor 0.00820233
S100A8 S100 calcium binding protein A8 0.00811671
CXCL8 chemokine (C-X-C motif) ligand 8 0.00810212
PLK2 polo-like kinase 2 0.00786807
CCL20 chemokine (C-C motif) ligand 20 0.00786251
TGFBI transforming growth factor, beta-induced, 68kDa 0.00781713
TRIB2 tribbles pseudokinase 2 0.00768376
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00766616
MAMLD1 mastermind-like domain containing 1 0.00754212
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00752643
EMX2 empty spiracles homeobox 2 0.0072252
RAI14 retinoic acid induced 14 0.00721012
TACSTD2 tumor-associated calcium signal transducer 2 0.00720763
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00720342
XIC X chromosome inactivation center 0.00714208
HTRA1 HtrA serine peptidase 1 0.00711158
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00706278
RGS4 regulator of G-protein signaling 4 0.00693478
NAMPT nicotinamide phosphoribosyltransferase 0.00691212
MYOF myoferlin 0.00691025
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00674659
NNMT nicotinamide N-methyltransferase 0.00672041
PEG10 paternally expressed 10 0.00669476
PF4 platelet factor 4 0.00657643
NELL1 NEL-like 1 (chicken) 0.00656999
WWTR1 WW domain containing transcription regulator 1 0.00653404
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00653391
EDN1 endothelin 1 0.0065224
LCN2 lipocalin 2 0.00642389
P3H2 prolyl 3-hydroxylase 2 0.00637238
ZIC1 Zic family member 1 0.00636967
S100A9 S100 calcium binding protein A9 0.00630972
CRYBG1 crystallin beta-gamma domain containing 1 0.00624554
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0061863
PLAAT3 phospholipase A and acyltransferase 3 0.00617735
VCL vinculin 0.00614395
PLBD1 phospholipase B domain containing 1 0.00614138
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00612277
MDK midkine (neurite growth-promoting factor 2) 0.00611705
EIF5A eukaryotic translation initiation factor 5A 0.00607168
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0060168
CCN2 cellular communication network factor 2 0.0059197
TFPI2 tissue factor pathway inhibitor 2 0.00589412
PI3 peptidase inhibitor 3, skin-derived 0.00585196
CSRP1 cysteine and glycine-rich protein 1 0.00585148
GDF15 growth differentiation factor 15 0.00582988
CSRP2 cysteine and glycine-rich protein 2 0.00580886
CD44 CD44 molecule (Indian blood group) 0.00580788
EVI2A ecotropic viral integration site 2A 0.00580662
BIN1 bridging integrator 1 0.00562849
MAL mal, T-cell differentiation protein 0.00558889
COL5A1 collagen, type V, alpha 1 0.00558443
CLEC2B C-type lectin domain family 2, member B 0.00558136
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00555397
LAMB1 laminin, beta 1 0.00552727
NID2 nidogen 2 (osteonidogen) 0.00550136
KLK10 kallikrein-related peptidase 10 0.00549235
STC1 stanniocalcin 1 0.00547544
NMU neuromedin U 0.00546575
MFAP3L microfibrillar-associated protein 3-like 0.00544651
YAP1 Yes-associated protein 1 0.0054446
AKAP12 A kinase (PRKA) anchor protein 12 0.00541883
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.0053978
CCNA2 cyclin A2 0.00539582
IL6ST interleukin 6 signal transducer 0.00539259
CFI complement factor I 0.00538964
SLPI secretory leukocyte peptidase inhibitor 0.00536737
NPAS2 neuronal PAS domain protein 2 0.00535565
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00535474
ARHGAP6 Rho GTPase activating protein 6 0.00535002
S100A10 S100 calcium binding protein A10 0.00529183
ITGAV integrin, alpha V 0.00527312
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00526284
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00521335
NRGN neurogranin (protein kinase C substrate, RC3) 0.00516754
SAMD4A sterile alpha motif domain containing 4A 0.00515376
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00514788
NFIB nuclear factor I/B 0.00514183
CNN3 calponin 3, acidic 0.00513543
LGALS1 lectin, galactoside-binding, soluble, 1 0.00510585
TPM4 tropomyosin 4 0.00508945
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00507837
FERMT2 fermitin family member 2 0.0050746
HIST1H2AC histone cluster 1, H2ac 0.00506854
EGR1 early growth response 1 0.00506497
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00505574
COL5A2 collagen, type V, alpha 2 0.0050292
PRAME preferentially expressed antigen in melanoma 0.00502401
FGFR1 fibroblast growth factor receptor 1 0.00501762
PLS3 plastin 3 0.00501455
VWF von Willebrand factor 0.0050143
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0050022
S100A7 S100 calcium binding protein A7 0.00499807
MAOB monoamine oxidase B 0.00499385
LRP4 low density lipoprotein receptor-related protein 4 0.0049857
TNC tenascin C 0.00498424
FABP7 fatty acid binding protein 7, brain 0.00496916
LOXL2 lysyl oxidase-like 2 0.00496618
EMP1 epithelial membrane protein 1 0.00493519
TAGLN2 transgelin 2 0.00491499
VNN1 vanin 1 0.00490903
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.0049084
C6ORF48 chromosome 6 open reading frame 48 0.00489764
FAM171A1 family with sequence similarity 171, member A1 0.00488554
COL6A3 collagen, type VI, alpha 3 0.00487961
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00486853
MT1F metallothionein 1F 0.00486667
RPS27L ribosomal protein S27-like 0.00486559
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00481946
GREB1 growth regulation by estrogen in breast cancer 1 0.00481664
CLTB clathrin, light chain B 0.00480708
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00480704
PPARG peroxisome proliferator-activated receptor gamma 0.00480004
KCTD12 potassium channel tetramerization domain containing 12 0.00477749
SPRY2 sprouty homolog 2 (Drosophila) 0.00476861
MX1 MX dynamin-like GTPase 1 0.00476262
CLDN10 claudin 10 0.00476202
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00475207
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00474936
AHNAK AHNAK nucleoprotein 0.0047328
SLN sarcolipin 0.00473262
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00470322
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00469659
KLK7 kallikrein-related peptidase 7 0.00469007
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00468458
GLIPR1 GLI pathogenesis-related 1 0.00468409
TPM1 tropomyosin 1 (alpha) 0.00468063
RNASET2 ribonuclease T2 0.00467044
CRYAB crystallin, alpha B 0.00466025
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00465902
DOK5 docking protein 5 0.00465693
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00464991
RIN2 Ras and Rab interactor 2 0.00464153
ICAM2 intercellular adhesion molecule 2 0.00463534
EPHA2 EPH receptor A2 0.00462802
TIMP1 TIMP metallopeptidase inhibitor 1 0.00459896
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00458517
ABHD6 abhydrolase domain containing 6 0.00454831
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00454576
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00454077
CXCL3 chemokine (C-X-C motif) ligand 3 0.0045333
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.00450577
AKR1C3 aldo-keto reductase family 1, member C3 0.00449926
ANXA1 annexin A1 0.0044981
WWC1 WW and C2 domain containing 1 0.00444164
PHF20 PHD finger protein 20 0.00443684
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00442584
IFI44 interferon-induced protein 44 0.00442148
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00439599
PDZK1IP1 PDZK1 interacting protein 1 0.00438647
NUTF2 nuclear transport factor 2 0.00438127
NCALD neurocalcin delta 0.00436282
BCL3 B-cell CLL/lymphoma 3 0.00433803
F2R coagulation factor II (thrombin) receptor 0.00433328
TJP2 tight junction protein 2 0.00431948
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.00431604
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00431511
CNTN1 contactin 1 0.00431285
CA6 carbonic anhydrase VI 0.00431195
IFI44L interferon-induced protein 44-like 0.00430045
ANXA2 annexin A2 0.00429235
LOR loricrin 0.00428169
KYNU kynureninase 0.00427804
ARHGAP29 Rho GTPase activating protein 29 0.00427633
IL1B interleukin 1, beta 0.00424076
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.00423819
NEBL nebulette 0.004236
NDRG1 N-myc downstream regulated 1 0.00423244
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00423008
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00422558
AQP3 aquaporin 3 (Gill blood group) 0.00422495
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00421793
TUBB2B tubulin, beta 2B class IIb 0.00421113
DOCK4 dedicator of cytokinesis 4 0.00420359
DPP4 dipeptidyl-peptidase 4 0.00418287
CAVIN2 caveolae associated protein 2 0.00417762
MYO6 myosin VI 0.00417719
HIST1H2BK histone cluster 1, H2bk 0.0041615
DNM1L dynamin 1-like 0.00415859
IFITM3 interferon induced transmembrane protein 3 0.00414944
SMYD3 SET and MYND domain containing 3 0.00413795
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00412377
GLUD1 glutamate dehydrogenase 1 0.00411101
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.00411063
HEBP2 heme binding protein 2 0.00410715
ACTN1 actinin, alpha 1 0.00409112
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00408893
SVIL supervillin 0.00408609
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00407935
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.00407521
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00407461
MT1H metallothionein 1H 0.004067
PCDH9 protocadherin 9 0.00405642
MT1E metallothionein 1E 0.00404967
LAMP5 lysosomal-associated membrane protein family, member 5 0.00400803
S100A2 S100 calcium binding protein A2 0.00400272
CLIC1 chloride intracellular channel 1 0.00399714
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00398515
NXN nucleoredoxin 0.00397071
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.0039701
COBL cordon-bleu WH2 repeat protein 0.00396459
EFNB2 ephrin-B2 0.00396218
CTNND1 catenin (cadherin-associated protein), delta 1 0.00395836
GLDC glycine dehydrogenase (decarboxylating) 0.00395593
TRIP6 thyroid hormone receptor interactor 6 0.00395323
HSPA1A heat shock 70kDa protein 1A 0.00394955
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 0.00394236
CAV2 caveolin 2 0.00393856
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.00392581
GFAP glial fibrillary acidic protein 0.00392514
SLIRP SRA stem-loop interacting RNA binding protein 0.00391259
PRKCA protein kinase C, alpha 0.00390704
PLIN2 perilipin 2 0.00390541
PDZD2 PDZ domain containing 2 0.00390377
MMRN1 multimerin 1 0.00389802
AOC1 amine oxidase, copper containing 1 0.00389525
TGFB2 transforming growth factor, beta 2 0.00389461
FLNB filamin B, beta 0.00389412
ISG15 ISG15 ubiquitin-like modifier 0.00388159
MGLL monoglyceride lipase 0.00387717
AMOTL2 angiomotin like 2 0.00387466
PRKCI protein kinase C, iota 0.00386795
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00385131
ANXA11 annexin A11 0.00383248
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00383136
CXCR4 chemokine (C-X-C motif) receptor 4 0.00382253
PERP PERP, TP53 apoptosis effector 0.00381927
COL4A1 collagen, type IV, alpha 1 0.00381628
DCLK1 doublecortin-like kinase 1 0.00381239
PTPRG protein tyrosine phosphatase, receptor type, G 0.0038122
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00381218
ZNF185 zinc finger protein 185 (LIM domain) 0.00381113
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00381047
FST follistatin 0.00380903
LDLR low density lipoprotein receptor 0.00380234
NDUFA4 NDUFA4, mitochondrial complex associated 0.00380124
PLXNA1 plexin A1 0.00379832
SOD2 superoxide dismutase 2, mitochondrial 0.00379705
COG7 component of oligomeric golgi complex 7 0.00377726

decreased expression

Symbol Name Standardized Value
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.016531
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0094481
CHGB chromogranin B -0.00909648
MAP7 microtubule-associated protein 7 -0.00811326
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00800631
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00794263
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00784486
SNX11 sorting nexin 11 -0.00713181
UGDH UDP-glucose 6-dehydrogenase -0.00711555
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.0070568
CA2 carbonic anhydrase II -0.00698663
KDM5D lysine (K)-specific demethylase 5D -0.00683015
LTF lactotransferrin -0.00680117
REEP1 receptor accessory protein 1 -0.00670779
TSPAN13 tetraspanin 13 -0.00667611
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00657974
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00655758
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -0.00653232
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00649175
NIT1 nitrilase 1 -0.00648112
RHOT1 ras homolog family member T1 -0.00644163
KRT19 keratin 19, type I -0.00641266
TOB1 transducer of ERBB2, 1 -0.00624022
SEPP1 selenoprotein P, plasma, 1 -0.00617044
DCXR dicarbonyl/L-xylulose reductase -0.00612632
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00611134
RET ret proto-oncogene -0.00607221
CDC20 cell division cycle 20 -0.00596274
SLIT2 slit homolog 2 (Drosophila) -0.00596201
CANT1 calcium activated nucleotidase 1 -0.00592128
MRPL12 mitochondrial ribosomal protein L12 -0.00591181
CENPX centromere protein X -0.00591006
CBX1 chromobox homolog 1 -0.00588348
SCGB1D2 secretoglobin, family 1D, member 2 -0.00586499
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00576582
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00574167
AMZ2 archaelysin family metallopeptidase 2 -0.00565764
MED13 mediator complex subunit 13 -0.00563076
FMO5 flavin containing monooxygenase 5 -0.00559716
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00552344
CRABP2 cellular retinoic acid binding protein 2 -0.00550898
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00548866
TRIM37 tripartite motif containing 37 -0.00542343
COIL coilin -0.00541271
STK10 serine/threonine kinase 10 -0.00540203
TMEM176B transmembrane protein 176B -0.00535151
KPNB1 karyopherin (importin) beta 1 -0.00534863
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00530341
MED1 mediator complex subunit 1 -0.00529743
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00529234
PON3 paraoxonase 3 -0.00528871
RGS13 regulator of G-protein signaling 13 -0.00527602
BRCA1 breast cancer 1, early onset -0.0052494
ISL1 ISL LIM homeobox 1 -0.00521313
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00521219
MPO myeloperoxidase -0.00518615
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00518339
DUT deoxyuridine triphosphatase -0.00517929
RUFY3 RUN and FYVE domain containing 3 -0.00517317
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00515147
TUBD1 tubulin, delta 1 -0.00506578
DPT dermatopontin -0.0050591
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00504331
PIP prolactin-induced protein -0.00503623
PCTP phosphatidylcholine transfer protein -0.00497345
TK1 thymidine kinase 1, soluble -0.00495051
APMAP adipocyte plasma membrane associated protein -0.00494895
CHD9 chromodomain helicase DNA binding protein 9 -0.00493755
MYH11 myosin, heavy chain 11, smooth muscle -0.00490084
BIRC5 baculoviral IAP repeat containing 5 -0.00488622
TOM1L1 target of myb1 (chicken)-like 1 -0.00488085
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00487921
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00486041
PTHLH parathyroid hormone-like hormone -0.00485658
SNF8 SNF8, ESCRT-II complex subunit -0.00485012
GGNBP2 gametogenetin binding protein 2 -0.00484989
SLC38A10 solute carrier family 38, member 10 -0.00484021
CCL19 chemokine (C-C motif) ligand 19 -0.00482354
SCGB2A2 secretoglobin, family 2A, member 2 -0.0048206
OLFM1 olfactomedin 1 -0.00481251
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -0.00480857
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00479823
TNS1 tensin 1 -0.00478927
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00478446
GREM1 gremlin 1, DAN family BMP antagonist -0.00476769
TLK2 tousled-like kinase 2 -0.00473604
CNPY2 canopy FGF signaling regulator 2 -0.00473239
CEP350 centrosomal protein 350kDa -0.00471608
BEX1 brain expressed, X-linked 1 -0.00468141
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00464141
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00463753
FASN fatty acid synthase -0.00463583
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.004626
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.00461203
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.00459559
RBM38 RNA binding motif protein 38 -0.00458703
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00457011
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00455327
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00450739
NOL11 nucleolar protein 11 -0.00449105
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00443093
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -0.00442102
INSM1 insulinoma-associated 1 -0.00441722
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00441682
CCP110 centriolar coiled coil protein 110kDa -0.00441114
NPTN neuroplastin -0.0044067
PRTN3 proteinase 3 -0.00440417
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -0.00439821
MTF2 metal response element binding transcription factor 2 -0.00439021
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -0.00436234
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -0.00435456
TMCO6 transmembrane and coiled-coil domains 6 -0.00434898
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00434377
CADPS2 Ca++-dependent secretion activator 2 -0.00433915
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -0.0043345
ARHGAP44 Rho GTPase activating protein 44 -0.0043271
UNG uracil-DNA glycosylase -0.00431819
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00429911
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00429762
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00429089
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00428802
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00428434
MRPS7 mitochondrial ribosomal protein S7 -0.00427537
ZBTB20 zinc finger and BTB domain containing 20 -0.00425949
AKAP1 A kinase (PRKA) anchor protein 1 -0.00425418
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) -0.00425007
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00423647
C17ORF75 chromosome 17 open reading frame 75 -0.00422855
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -0.00422201
SFTPB surfactant protein B -0.00420951
MTMR4 myotubularin related protein 4 -0.00420084
TUBG1 tubulin, gamma 1 -0.00418489
TRAPPC8 trafficking protein particle complex 8 -0.00417911
AQP8 aquaporin 8 -0.00417591
MSL1 male-specific lethal 1 homolog (Drosophila) -0.00416511
TEX2 testis expressed 2 -0.00415472
UBE2Z ubiquitin-conjugating enzyme E2Z -0.00415303
MMP1 matrix metallopeptidase 1 -0.00413355
NKX2-1 NK2 homeobox 1 -0.00413116
FOXO4 forkhead box O4 -0.00412587
NFE2L1 nuclear factor, erythroid 2-like 1 -0.00411678
FERMT1 fermitin family member 1 -0.0041167
MST1 macrophage stimulating 1 -0.00411342
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00410897
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.00409323
CPA3 carboxypeptidase A3 (mast cell) -0.00407474
TP63 tumor protein p63 -0.00406229
CBR4 carbonyl reductase 4 -0.00403804
SEPTIN9 septin 9 -0.00402902
HOXA5 homeobox A5 -0.00402665
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00400127
NR1H3 nuclear receptor subfamily 1, group H, member 3 -0.00398513
ASXL2 additional sex combs like transcriptional regulator 2 -0.00398305
COA3 cytochrome c oxidase assembly factor 3 -0.00398053
GPX3 glutathione peroxidase 3 -0.00397
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00396086
L1CAM L1 cell adhesion molecule -0.0039593
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -0.00395442
LUM lumican -0.00395024
XPO7 exportin 7 -0.00394904
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00394778
SYNGR2 synaptogyrin 2 -0.00394607
GOLGA8H golgin A8 family, member H -0.00394345
PDGFRL platelet-derived growth factor receptor-like -0.00393781
NFS1 NFS1 cysteine desulfurase -0.00393632
DIXDC1 DIX domain containing 1 -0.00390356
ADAMDEC1 ADAM-like, decysin 1 -0.00387607
ADA adenosine deaminase -0.00387085
RETREG1 reticulophagy regulator 1 -0.00386599
OXLD1 oxidoreductase-like domain containing 1 -0.00385373
MYO1D myosin ID -0.00383877
DENND1B DENN/MADD domain containing 1B -0.0038328
SETD6 SET domain containing 6 -0.00382422
WIPF2 WAS/WASL interacting protein family, member 2 -0.00380717
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00380347
EIF4A3 eukaryotic translation initiation factor 4A3 -0.00379357
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00378855
ISOC1 isochorismatase domain containing 1 -0.00378623
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00378104
SCGB2A1 secretoglobin, family 2A, member 1 -0.00376745
KRT15 keratin 15, type I -0.00376658
GSTA1 glutathione S-transferase alpha 1 -0.00374964
NSF N-ethylmaleimide-sensitive factor -0.00374783
XK X-linked Kx blood group -0.00374659
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -0.00374619
RBFA ribosome binding factor A (putative) -0.00374178
FMO3 flavin containing monooxygenase 3 -0.00373985
RPIA ribose 5-phosphate isomerase A -0.00373461
GUSBP3 glucuronidase, beta pseudogene 3 -0.00373133
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00372659
TRIP13 thyroid hormone receptor interactor 13 -0.00367936
CTSZ cathepsin Z -0.0036783
NPEPPS aminopeptidase puromycin sensitive -0.00367728
MFAP4 microfibrillar-associated protein 4 -0.00367258
CLU clusterin -0.00366249
LRRC59 leucine rich repeat containing 59 -0.00364833
RGS5 regulator of G-protein signaling 5 -0.00364221
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00364187
KLHL21 kelch-like family member 21 -0.00362807
TMEM106C transmembrane protein 106C -0.00361991
SRSF1 serine/arginine-rich splicing factor 1 -0.00361659
FGL2 fibrinogen-like 2 -0.00361559
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -0.00360617
H2AX H2A.X variant histone -0.00359628
SIRT7 sirtuin 7 -0.00359546
ELANE elastase, neutrophil expressed -0.00359181
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -0.00358983
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00358858
CTSK cathepsin K -0.00358574
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -0.00358521
ROR2 receptor tyrosine kinase-like orphan receptor 2 -0.00358136
TMED2 transmembrane emp24 domain trafficking protein 2 -0.00358068
BCAP31 B-cell receptor-associated protein 31 -0.00357973
HMBS hydroxymethylbilane synthase -0.00356896
NF1 neurofibromin 1 -0.00356511
ELP1 elongator acetyltransferase complex subunit 1 -0.0035651
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -0.00356267
CLCA1 chloride channel accessory 1 -0.0035582
PGF placental growth factor -0.00353778
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.00353655
SI sucrase-isomaltase (alpha-glucosidase) -0.00353457
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00352712
PCGF2 polycomb group ring finger 2 -0.003508
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00350763
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -0.00350761
CLGN calmegin -0.00349894
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00349706
ALG6 ALG6, alpha-1,3-glucosyltransferase -0.00349593
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00349277
MALL mal, T-cell differentiation protein-like -0.00348736
CALCA calcitonin-related polypeptide alpha -0.00348157
MMP9 matrix metallopeptidase 9 -0.00347771
TEFM transcription elongation factor, mitochondrial -0.00345986
LIMA1 LIM domain and actin binding 1 -0.00345192
CPE carboxypeptidase E -0.00344918
CYB5R2 cytochrome b5 reductase 2 -0.00344382
ZNF12 zinc finger protein 12 -0.00344256
GOLPH3L golgi phosphoprotein 3-like -0.00343642
GPS1 G protein pathway suppressor 1 -0.00343319
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -0.00342953
CRLF3 cytokine receptor-like factor 3 -0.00342405
TCTN1 tectonic family member 1 -0.00341064
ZG16 zymogen granule protein 16 -0.00339861
MSX1 msh homeobox 1 -0.00338656
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00338039
EVA1B eva-1 homolog B (C. elegans) -0.00336898
OIP5 Opa interacting protein 5 -0.00336661
BPTF bromodomain PHD finger transcription factor -0.00335861
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00335206