SUZ12 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description SUZ12 polycomb repressive complex 2 subunit|This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. [provided by RefSeq, Jul 2009] (NCBI Entrez Gene Database, 23512)
External Link http://www.ncbi.nlm.nih.gov/gene/23512
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Genes

438 interacting proteins for SUZ12 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABLIM1 actin binding LIM protein 1
ACACA acetyl-CoA carboxylase alpha
ACIN1 apoptotic chromatin condensation inducer 1
ACTG1 actin gamma 1
ACTL6A actin-like 6A
ADAR adenosine deaminase, RNA-specific
ADNP activity-dependent neuroprotector homeobox
AEBP2 AE binding protein 2
AFG3L2 AFG3-like AAA ATPase 2
AHDC1 AT hook, DNA binding motif, containing 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKAP9 A kinase (PRKA) anchor protein 9
ALDOA aldolase A, fructose-bisphosphate
ALYREF Aly/REF export factor
AMOTL1 angiomotin like 1
AQR aquarius intron-binding spliceosomal factor
AR androgen receptor
ARG1 arginase 1
ASXL1 additional sex combs like transcriptional regulator 1
ATAD3A ATPase family, AAA domain containing 3A
ATF2 activating transcription factor 2
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
AURKB aurora kinase B
BCAS2 breast carcinoma amplified sequence 2
BCL7A B-cell CLL/lymphoma 7A
BCLAF1 BCL2-associated transcription factor 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF12 chromosome 10 open reading frame 12
C15ORF52 chromosome 15 open reading frame 52
C17ORF85 chromosome 17 open reading frame 85
C1QBP complement component 1, q subcomponent binding protein
CALR calreticulin
CANX calnexin
CBX1 chromobox homolog 1
CBX3 chromobox homolog 3
CBX5 chromobox homolog 5
CBX8 chromobox homolog 8
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CDC40 cell division cycle 40
CDCA8 cell division cycle associated 8
CDK19 cyclin-dependent kinase 19
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK8 cyclin-dependent kinase 8
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDYL chromodomain protein, Y-like
CEP57 centrosomal protein 57kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHD4 chromodomain helicase DNA binding protein 4
CHTOP chromatin target of PRMT1
CKMT1A creatine kinase, mitochondrial 1A
CNBP CCHC-type zinc finger, nucleic acid binding protein
COPA coatomer protein complex, subunit alpha
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CREB1 cAMP responsive element binding protein 1
CRNKL1 crooked neck pre-mRNA splicing factor 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK2B casein kinase 2, beta polypeptide
CSRP1 cysteine and glycine-rich protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CUL4B cullin 4B
DAZAP1 DAZ associated protein 1
DBN1 drebrin 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DKC1 dyskeratosis congenita 1, dyskerin
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSN1 DSN1, MIS12 kinetochore complex component
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EBNA1BP2 EBNA1 binding protein 2
EED embryonic ectoderm development
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4A3 eukaryotic translation initiation factor 4A3
ELAVL1 ELAV like RNA binding protein 1
EMD emerin
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPRS glutamyl-prolyl-tRNA synthetase
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
ERH enhancer of rudimentary homolog (Drosophila)
ERLIN1 ER lipid raft associated 1
EWSR1 EWS RNA-binding protein 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM208A family with sequence similarity 208, member A
FBL fibrillarin
FIP1L1 factor interacting with PAPOLA and CPSF1
FLNB filamin B, beta
FMR1 fragile X mental retardation 1
FUBP3 far upstream element (FUSE) binding protein 3
FUS FUS RNA binding protein
FXR1 fragile X mental retardation, autosomal homolog 1
FXR2 fragile X mental retardation, autosomal homolog 2
FYTTD1 forty-two-three domain containing 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GATA4 GATA binding protein 4
GATAD2B GATA zinc finger domain containing 2B
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GDAP1 ganglioside induced differentiation associated protein 1
GLDC glycine dehydrogenase (decarboxylating)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSDMA gasdermin A
GTF2I general transcription factor IIi
GTPBP4 GTP binding protein 4
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
H2AFB1 H2A histone family, member B1
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
H2AFY2 H2A histone family, member Y2
H2AFZ H2A histone family, member Z
H2BFS H2B histone family, member S (pseudogene)
H3F3A H3 histone, family 3A
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HEATR1 HEAT repeat containing 1
HIC1 hypermethylated in cancer 1
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BA histone cluster 1, H2ba
HIST1H2BB histone cluster 1, H2bb
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H2AB histone cluster 2, H2ab
HIST2H2AC histone cluster 2, H2ac
HIST2H2BE histone cluster 2, H2be
HIST2H3A histone cluster 2, H3a
HIST3H2BB histone cluster 3, H2bb
HIST3H3 histone cluster 3, H3
HLX H2.0-like homeobox
HOXA9 homeobox A9
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA1B heat shock 70kDa protein 1B
IGLL5 immunoglobulin lambda-like polypeptide 5
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IMMT inner membrane protein, mitochondrial
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
JARID2 jumonji, AT rich interactive domain 2
KDM5A lysine (K)-specific demethylase 5A
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KLK2 kallikrein-related peptidase 2
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LARP1 La ribonucleoprotein domain family, member 1
LDHB lactate dehydrogenase B
LGALS7B lectin, galactoside-binding, soluble, 7B
LIMA1 LIM domain and actin binding 1
LMNB2 lamin B2
LPP LIM domain containing preferred translocation partner in lipoma
LRIF1 ligand dependent nuclear receptor interacting factor 1
LUC7L LUC7-like (S. cerevisiae)
LUC7L2 LUC7-like 2 (S. cerevisiae)
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAP7D3 MAP7 domain containing 3
MAU2 MAU2 sister chromatid cohesion factor
MCM7 minichromosome maintenance complex component 7
MED17 mediator complex subunit 17
MED6 mediator complex subunit 6
MFAP1 microfibrillar-associated protein 1
MIS12 MIS12 kinetochore complex component
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MSI2 musashi RNA-binding protein 2
MTA1 metastasis associated 1
MTF2 metal response element binding transcription factor 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH14 myosin, heavy chain 14, non-muscle
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO1C myosin IC
NARF nuclear prelamin A recognition factor
NAT10 N-acetyltransferase 10 (GCN5-related)
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NDRG1 N-myc downstream regulated 1
NGDN neuroguidin, EIF4E binding protein
NHP2 NHP2 ribonucleoprotein
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NIPBL Nipped-B homolog (Drosophila)
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP2 NOP2 nucleolar protein
NOP58 NOP58 ribonucleoprotein
NSL1 NSL1, MIS12 kinetochore complex component
NUCLEOLIN nucleolin multifunctional protein
NUMA1 nuclear mitotic apparatus protein 1
NUP107 nucleoporin 107kDa
NUP88 nucleoporin 88kDa
NUP93 nucleoporin 93kDa
NXF1 nuclear RNA export factor 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PABPN1 poly(A) binding protein, nuclear 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCNT pericentrin
PDCD11 programmed cell death 11
PDIA3 protein disulfide isomerase family A, member 3
PDLIM5 PDZ and LIM domain 5
PGAM5 phosphoglycerate mutase family member 5
PHB prohibitin
PHB2 prohibitin 2
PHF1 PHD finger protein 1
PHF19 PHD finger protein 19
PHF5A PHD finger protein 5A
PHGDH phosphoglycerate dehydrogenase
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKM pyruvate kinase, muscle
PKP1 plakophilin 1
PLEC plectin
PLG plasminogen
PLRG1 pleiotropic regulator 1
PMF1 polyamine-modulated factor 1
PML promyelocytic leukemia
POGZ pogo transposable element with ZNF domain
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRDX1 peroxiredoxin 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT1 protein arginine methyltransferase 1
PRPF19 pre-mRNA processing factor 19
PRPF8 pre-mRNA processing factor 8
PRR14 proline rich 14
PTBP1 polypyrimidine tract binding protein 1
PTCD3 pentatricopeptide repeat domain 3
PYCR1 pyrroline-5-carboxylate reductase 1
RALY RALY heterogeneous nuclear ribonucleoprotein
RAN RAN, member RAS oncogene family
RANBP2 RAN binding protein 2
RARA retinoic acid receptor, alpha
RARG retinoic acid receptor, gamma
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RBM14 RNA binding motif protein 14
RBM15B RNA binding motif protein 15B
RBM22 RNA binding motif protein 22
RBM34 RNA binding motif protein 34
RBM39 RNA binding motif protein 39
RBM4 RNA binding motif protein 4
RBM4B RNA binding motif protein 4B
RBM5 RNA binding motif protein 5
RBM8A RNA binding motif protein 8A
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCC1 regulator of chromosome condensation 1
RCL1 RNA terminal phosphate cyclase-like 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REPIN1 replication initiator 1
RLF rearranged L-myc fusion
RNF114 ring finger protein 114
RNF2 ring finger protein 2
RNPS1 RNA binding protein S1, serine-rich domain
RPL26 ribosomal protein L26
RPL26L1 ribosomal protein L26-like 1
RPL5 ribosomal protein L5
RSL1D1 ribosomal L1 domain containing 1
RUVBL2 RuvB-like AAA ATPase 2
SAFB2 scaffold attachment factor B2
SAMM50 SAMM50 sorting and assembly machinery component
SAP18 Sin3A-associated protein, 18kDa
SART1 squamous cell carcinoma antigen recognized by T cells
SCAI suppressor of cancer cell invasion
SDF2L1 stromal cell-derived factor 2-like 1
SENP7 SUMO1/sentrin specific peptidase 7
SETD8 SET domain containing (lysine methyltransferase) 8
SETDB1 SET domain, bifurcated 1
SF1 splicing factor 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3A3 splicing factor 3a, subunit 3, 60kDa
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SF3B4 splicing factor 3b, subunit 4, 49kDa
SFXN1 sideroflexin 1
SGOL1 shugoshin-like 1 (S. pombe)
SIRT1 sirtuin 1
SKP1 S-phase kinase-associated protein 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLTM SAFB-like, transcription modulator
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC3 structural maintenance of chromosomes 3
SNAI1 snail family zinc finger 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPN small nuclear ribonucleoprotein polypeptide N
SNW1 SNW domain containing 1
SON SON DNA binding protein
SORBS2 sorbin and SH3 domain containing 2
SPRR2G small proline-rich protein 2G
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
SRSF3 serine/arginine-rich splicing factor 3
SRSF5 serine/arginine-rich splicing factor 5
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
SRSF8 serine/arginine-rich splicing factor 8
SRSF9 serine/arginine-rich splicing factor 9
SS18 synovial sarcoma translocation, chromosome 18
SSB Sjogren syndrome antigen B (autoantigen La)
SSR4 signal sequence receptor, delta
SSX2 synovial sarcoma, X breakpoint 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOML2 stomatin (EPB72)-like 2
SUMO2 small ubiquitin-like modifier 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL1Y transducin (beta)-like 1, Y-linked
TBL2 transducin (beta)-like 2
TFAM transcription factor A, mitochondrial
THOC2 THO complex 2
THOC6 THO complex 6
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM7SF2 transmembrane 7 superfamily member 2
TPI1 triosephosphate isomerase 1
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF4 TNF receptor-associated factor 4
TRIM25 tripartite motif containing 25
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBB ubiquitin B
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
UFD1L ubiquitin fusion degradation 1 like (yeast)
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
VAV1 vav 1 guanine nucleotide exchange factor
VCP valosin containing protein
VGF VGF nerve growth factor inducible
WDR77 WD repeat domain 77
WIZ widely interspaced zinc finger motifs
WT1 Wilms tumor 1
XAB2 XPA binding protein 2
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YY1 YY1 transcription factor
ZC3H13 zinc finger CCCH-type containing 13
ZFP1 ZFP1 zinc finger protein
ZFP82 ZFP82 zinc finger protein
ZMYM3 zinc finger, MYM-type 3
ZNF195 zinc finger protein 195
ZNF227 zinc finger protein 227
ZNF264 zinc finger protein 264
ZNF274 zinc finger protein 274
ZNF280D zinc finger protein 280D
ZNF302 zinc finger protein 302
ZNF324 zinc finger protein 324
ZNF324B zinc finger protein 324B
ZNF326 zinc finger protein 326
ZNF45 zinc finger protein 45
ZNF460 zinc finger protein 460
ZNF462 zinc finger protein 462
ZNF483 zinc finger protein 483
ZNF518A zinc finger protein 518A
ZNF552 zinc finger protein 552
ZNF566 zinc finger protein 566
ZNF568 zinc finger protein 568
ZNF569 zinc finger protein 569
ZNF585A zinc finger protein 585A
ZNF585B zinc finger protein 585B
ZNF620 zinc finger protein 620
ZNF625 zinc finger protein 625
ZNF649 zinc finger protein 649
ZNF688 zinc finger protein 688
ZNF689 zinc finger protein 689
ZNF724P zinc finger protein 724, pseudogene
ZNF747 zinc finger protein 747
ZNF764 zinc finger protein 764
ZNF773 zinc finger protein 773
ZNF8 zinc finger protein 8
ZNF829 zinc finger protein 829