SW1116 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

289 genes with high or low expression in SW1116 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
ATP10B ATPase, class V, type 10B 2.5111
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 2.36295
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.27371
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 2.2289
TM4SF20 transmembrane 4 L six family member 20 2.16511
IL22RA1 interleukin 22 receptor, alpha 1 2.15261
HNF1A HNF1 homeobox A 2.14044
RNF170 ring finger protein 170 2.13947
CDX1 caudal type homeobox 1 2.13214
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 2.10763
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.10061
MYO1A myosin IA 2.09514
KNG1 kininogen 1 2.08575
EFTUD1 elongation factor Tu GTP binding domain containing 1 2.0543
KRT23 keratin 23, type I 2.04601
GPR35 G protein-coupled receptor 35 2.04147
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.0262
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 2.02155
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 2.0208
SIRAL2 SIR2 antiphage like 2 2.01446
ACSL5 acyl-CoA synthetase long-chain family member 5 1.98689
GAST gastrin 1.98396
LPIN2 lipin 2 1.97743
GUCA2A guanylate cyclase activator 2A (guanylin) 1.97204
OR11A1 olfactory receptor, family 11, subfamily A, member 1 1.96654
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.95513
TTC19 tetratricopeptide repeat domain 19 1.95154
MUC13 mucin 13, cell surface associated 1.94945
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 1.94789
GALC galactosylceramidase 1.94287
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 1.92463
MMP7 matrix metallopeptidase 7 1.92325
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.90144
HEPH hephaestin 1.89075
CDHR2 cadherin-related family member 2 1.86167
VDAC1 voltage-dependent anion channel 1 1.86157
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.83987
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 1.831
BCL2L14 BCL2-like 14 (apoptosis facilitator) 1.83071
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 1.82984
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.82363
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 1.81866
TM9SF3 transmembrane 9 superfamily member 3 1.78085
ANKMY2 ankyrin repeat and MYND domain containing 2 1.77507
POFUT1 protein O-fucosyltransferase 1 1.77124
IHH indian hedgehog 1.76895
TRIM31 tripartite motif containing 31 1.76852
PTGES2 prostaglandin E synthase 2 1.75674
PML promyelocytic leukemia 1.74796
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 1.74446
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.73842
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 1.73378
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.72479
ADAP1 ArfGAP with dual PH domains 1 1.7241
PARP4 poly (ADP-ribose) polymerase family, member 4 1.72359
ACY1 aminoacylase 1 1.71722
FBXO34 F-box protein 34 1.71483
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.71136
SI sucrase-isomaltase (alpha-glucosidase) 1.70978
SURF1 surfeit 1 1.70657
SERINC5 serine incorporator 5 1.70584
CELP carboxyl ester lipase pseudogene 1.70062
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.70044
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 1.69414
CDX2 caudal type homeobox 2 1.69231
GPX3 glutathione peroxidase 3 1.69085
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 1.68936
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.6866
ANXA13 annexin A13 1.67715
HMOX2 heme oxygenase 2 1.66131
MEP1A meprin A, alpha (PABA peptide hydrolase) 1.65554
KRT20 keratin 20, type I 1.65241
CDK7 cyclin-dependent kinase 7 1.65234
UNG uracil-DNA glycosylase 1.64618
USH1C Usher syndrome 1C (autosomal recessive, severe) 1.64522
FABP2 fatty acid binding protein 2, intestinal 1.64332
PLS1 plastin 1 1.63517
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 1.62065
BMP4 bone morphogenetic protein 4 1.61923
PDZD3 PDZ domain containing 3 1.61505
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.60563
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.60147
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.59902
CLDN3 claudin 3 1.59648
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 1.5956
CLCN2 chloride channel, voltage-sensitive 2 1.59397
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.59264
KLK6 kallikrein-related peptidase 6 1.59208
POF1B premature ovarian failure, 1B 1.59009
PEPD peptidase D 1.58775
MSLN mesothelin 1.58633
GALE UDP-galactose-4-epimerase 1.58524
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.58513
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.57813
ARHGAP26 Rho GTPase activating protein 26 1.57793
FABP1 fatty acid binding protein 1, liver 1.57585
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.57375
STK39 serine threonine kinase 39 1.57188
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 1.56582
TMC5 transmembrane channel-like 5 1.56539
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.56508
MAEA macrophage erythroblast attacher 1.56275
PROSC proline synthetase co-transcribed homolog (bacterial) 1.55305
GUCY2C guanylate cyclase 2C 1.54813
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.545
HHLA2 HERV-H LTR-associating 2 1.54431
DPEP1 dipeptidase 1 (renal) 1.54388
MUC3B mucin 3B, cell surface associated 1.54139
PTPRO protein tyrosine phosphatase, receptor type, O 1.53214
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.53195
RNF43 ring finger protein 43 1.52997
CEL carboxyl ester lipase 1.52405
NIT2 nitrilase family, member 2 1.52007
MRPS22 mitochondrial ribosomal protein S22 1.51845
CALML4 calmodulin-like 4 1.50855
CDHR5 cadherin-related family member 5 1.50573
GPA33 glycoprotein A33 (transmembrane) 1.50547
NMU neuromedin U 1.49964
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 1.49805
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.49373
ANXA4 annexin A4 1.49258
LGALS4 lectin, galactoside-binding, soluble, 4 1.49213
EPS8L3 EPS8-like 3 1.48867
RAD50 RAD50 homolog (S. cerevisiae) 1.48528
CRYL1 crystallin, lambda 1 1.48095
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 1.47967
KLK7 kallikrein-related peptidase 7 1.4739
GPX2 glutathione peroxidase 2 1.47153
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.46676
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 1.46639
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.46345
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 1.46163
EDN1 endothelin 1 1.45498
NOD1 nucleotide-binding oligomerization domain containing 1 1.44932
AKR1C4 aldo-keto reductase family 1, member C4 1.44428
TM4SF4 transmembrane 4 L six family member 4 1.44135
ARL14 ADP-ribosylation factor-like 14 1.43013
VIL1 villin 1 1.42655
WDR73 WD repeat domain 73 1.42372
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.42292
TSPAN8 tetraspanin 8 1.4177
ATP9A ATPase, class II, type 9A 1.41767

low expression

Symbol Name Standardized Value
ZNF236 zinc finger protein 236 -3.53725
ZNF669 zinc finger protein 669 -3.53725
ZNF271P zinc finger protein 271, pseudogene -3.53725
CSNK1G1 casein kinase 1, gamma 1 -3.53724
FTO fat mass and obesity associated -3.00061
LONRF1 LON peptidase N-terminal domain and ring finger 1 -2.99847
RFX7 regulatory factor X, 7 -2.92992
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.7646
BBS4 Bardet-Biedl syndrome 4 -2.56384
OAZ2 ornithine decarboxylase antizyme 2 -2.49456
BTN2A2 butyrophilin, subfamily 2, member A2 -2.43272
IPO8 importin 8 -2.43068
FAM168A family with sequence similarity 168, member A -2.39577
ZNF419 zinc finger protein 419 -2.36023
KLF9 Kruppel-like factor 9 -2.35863
TIAM1 T-cell lymphoma invasion and metastasis 1 -2.35362
WDR26 WD repeat domain 26 -2.31008
WDR7 WD repeat domain 7 -2.26637
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -2.25103
DTNA dystrobrevin, alpha -2.22433
NUCB1 nucleobindin 1 -2.22257
MARK4 MAP/microtubule affinity-regulating kinase 4 -2.22104
SIKE1 suppressor of IKBKE 1 -2.21241
WRN Werner syndrome, RecQ helicase-like -2.20612
GEMIN8 gem (nuclear organelle) associated protein 8 -2.18238
PLD3 phospholipase D family, member 3 -2.17167
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.13611
IL1B interleukin 1, beta -2.12356
WDR4 WD repeat domain 4 -2.11774
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -2.11061
SMC5 structural maintenance of chromosomes 5 -2.09567
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -2.07997
METTL16 methyltransferase like 16 -2.05612
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -2.03683
PTH1R parathyroid hormone 1 receptor -2.02524
MPDZ multiple PDZ domain protein -2.00682
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -2.00528
MAGEF1 melanoma antigen family F1 -2.00327
NBPF10 neuroblastoma breakpoint family, member 10 -2.00214
CECR7 cat eye syndrome chromosome region, candidate 7 (non-protein coding) -1.97923
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -1.96767
MYO15A myosin XVA -1.96094
ATRN attractin -1.93586
DNAH17 dynein, axonemal, heavy chain 17 -1.9135
AQP1 aquaporin 1 (Colton blood group) -1.90235
CSAD cysteine sulfinic acid decarboxylase -1.89938
GON4L gon-4-like (C. elegans) -1.89483
PTPRA protein tyrosine phosphatase, receptor type, A -1.8828
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -1.87791
PTOV1 prostate tumor overexpressed 1 -1.86865
TRAPPC8 trafficking protein particle complex 8 -1.86458
PCDHA5 protocadherin alpha 5 -1.8518
SMAD4 SMAD family member 4 -1.85112
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -1.84035
MTMR7 myotubularin related protein 7 -1.83219
PER3 period circadian clock 3 -1.81331
ZNF274 zinc finger protein 274 -1.77855
TSPAN4 tetraspanin 4 -1.77636
ADRA1A adrenoceptor alpha 1A -1.76846
PEX19 peroxisomal biogenesis factor 19 -1.76577
BBS9 Bardet-Biedl syndrome 9 -1.76565
CPA2 carboxypeptidase A2 (pancreatic) -1.76426
MTMR9 myotubularin related protein 9 -1.76126
TROVE2 TROVE domain family, member 2 -1.76042
ZNF134 zinc finger protein 134 -1.75652
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -1.74969
DTNB dystrobrevin, beta -1.74065
PRAF2 PRA1 domain family, member 2 -1.73485
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -1.73059
ZNF428 zinc finger protein 428 -1.73019
CCDC28B coiled-coil domain containing 28B -1.72931
LMTK2 lemur tyrosine kinase 2 -1.7236
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.71692
PIAS3 protein inhibitor of activated STAT, 3 -1.71255
ZNF264 zinc finger protein 264 -1.70648
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -1.69465
PRKCB protein kinase C, beta -1.69302
SARAF store-operated calcium entry-associated regulatory factor -1.66966
PHF3 PHD finger protein 3 -1.66043
SCPEP1 serine carboxypeptidase 1 -1.6531
SCG2 secretogranin II -1.64953
ATP10D ATPase, class V, type 10D -1.64945
ZNF652 zinc finger protein 652 -1.63951
CLIC2 chloride intracellular channel 2 -1.63928
IFT22 intraflagellar transport 22 -1.63099
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -1.62821
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 -1.6253
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -1.61402
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.61287
MOCS1 molybdenum cofactor synthesis 1 -1.60492
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -1.60114
APH1A APH1A gamma secretase subunit -1.59325
EMX1 empty spiracles homeobox 1 -1.593
MDFIC MyoD family inhibitor domain containing -1.5882
EMID1 EMI domain containing 1 -1.58578
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -1.58256
SNAI2 snail family zinc finger 2 -1.58036
GOLGA8A golgin A8 family, member A -1.57904
CD3D CD3d molecule, delta (CD3-TCR complex) -1.57601
GAMT guanidinoacetate N-methyltransferase -1.57531
CA11 carbonic anhydrase XI -1.57529
FMNL2 formin-like 2 -1.56639
SMAD2 SMAD family member 2 -1.56591
FABP3 fatty acid binding protein 3, muscle and heart -1.56277
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -1.56208
ANKRD6 ankyrin repeat domain 6 -1.56201
LTBP4 latent transforming growth factor beta binding protein 4 -1.56053
RIBC2 RIB43A domain with coiled-coils 2 -1.55731
CEP170 centrosomal protein 170kDa -1.55571
MDM1 Mdm1 nuclear protein homolog (mouse) -1.54978
MCOLN1 mucolipin 1 -1.54666
MYCNOS MYCN opposite strand -1.54076
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -1.53719
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -1.53171
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -1.52742
TCEA2 transcription elongation factor A (SII), 2 -1.52636
CP ceruloplasmin (ferroxidase) -1.52479
IFNA16 interferon, alpha 16 -1.51624
POGZ pogo transposable element with ZNF domain -1.50431
DIO2 deiodinase, iodothyronine, type II -1.50366
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -1.49133
TTBK2 tau tubulin kinase 2 -1.49057
UBOX5 U-box domain containing 5 -1.48917
ARHGAP33 Rho GTPase activating protein 33 -1.48829
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -1.48783
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.48032
CTIF CBP80/20-dependent translation initiation factor -1.47851
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -1.47758
ZNF512B zinc finger protein 512B -1.47688
NEK1 NIMA-related kinase 1 -1.47089
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.46954
RAB8B RAB8B, member RAS oncogene family -1.46124
MDM4 MDM4, p53 regulator -1.4558
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -1.45525
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -1.44945
ARHGAP25 Rho GTPase activating protein 25 -1.4441
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -1.44304
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -1.44167
ARMC9 armadillo repeat containing 9 -1.43952
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -1.43626
RIT1 Ras-like without CAAX 1 -1.43573
NEK11 NIMA-related kinase 11 -1.43047
PDE4B phosphodiesterase 4B, cAMP-specific -1.42988
ZMYM4 zinc finger, MYM-type 4 -1.42826
ZCCHC2 zinc finger, CCHC domain containing 2 -1.42417
KLF12 Kruppel-like factor 12 -1.42015
R3HCC1 R3H domain and coiled-coil containing 1 -1.41687