SW1417 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

514 gene knockdowns changing fitness of SW1417 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
MTMR1 myotubularin related protein 1 3.19303
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 3.19202
LOC652119 3.14528
CTNNBL1 catenin, beta like 1 2.5057
CCNE2 cyclin E2 2.45038
DGKA diacylglycerol kinase, alpha 80kDa 2.38219
LAMA2 laminin, alpha 2 2.35382
LENG8 leukocyte receptor cluster (LRC) member 8 2.3237
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.30637
ADAM12 ADAM metallopeptidase domain 12 2.25036
TIPE2 TNF alpha induced protein 8 like 2 2.20313
ZNF701 zinc finger protein 701 2.19932
TNIP1 TNFAIP3 interacting protein 1 2.18075
CPT1B carnitine palmitoyltransferase 1B (muscle) 2.1704
KRTAP5-2 keratin associated protein 5-2 2.14637
KRT1 keratin 1, type II 2.12415
IRF8 interferon regulatory factor 8 2.11546
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.06516
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 2.03628
PEG3 paternally expressed 3 2.00177
SYT15 synaptotagmin XV 1.99228
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.96627
CPPED1 calcineurin-like phosphoesterase domain containing 1 1.96141
PARP16 poly (ADP-ribose) polymerase family, member 16 1.95531
ZBTB3 zinc finger and BTB domain containing 3 1.89808
OR7C2 olfactory receptor, family 7, subfamily C, member 2 1.86972
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 1.866
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 1.84103
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 1.82447
SCARA3 scavenger receptor class A, member 3 1.81164
BRIP1 BRCA1 interacting protein C-terminal helicase 1 1.79532
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.79523
ZNF154 zinc finger protein 154 1.76712
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.75497
PRCP prolylcarboxypeptidase (angiotensinase C) 1.75471
UBL3 ubiquitin-like 3 1.72959
C5 complement component 5 1.72003
TSTA3 tissue specific transplantation antigen P35B 1.67761
KLHL4 kelch-like family member 4 1.67568
FOXM1 forkhead box M1 1.67371
PGRMC2 progesterone receptor membrane component 2 1.66744
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 1.66285
TRPM3 transient receptor potential cation channel, subfamily M, member 3 1.66128
APAF1 apoptotic peptidase activating factor 1 1.66083
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 1.65143
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 1.63995
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.6194
HCFC2 host cell factor C2 1.61198
PAQR8 progestin and adipoQ receptor family member VIII 1.608
MORF4L1 mortality factor 4 like 1 1.60687
RPS29 ribosomal protein S29 1.60086
LY75-CD302 LY75-CD302 readthrough 1.59292
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.58365
PCSK9 proprotein convertase subtilisin/kexin type 9 1.5835
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.57705
TRIP10 thyroid hormone receptor interactor 10 1.56796
PLXNA3 plexin A3 1.56615
PAQR3 progestin and adipoQ receptor family member III 1.56345
TREML2 triggering receptor expressed on myeloid cells-like 2 1.5605
BCL9L B-cell CLL/lymphoma 9-like 1.55563
TUBB8 tubulin, beta 8 class VIII 1.53903
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 1.53586
NME3 NME/NM23 nucleoside diphosphate kinase 3 1.53104
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.52731
KCNK10 potassium channel, two pore domain subfamily K, member 10 1.52403
OR7G2 olfactory receptor, family 7, subfamily G, member 2 1.52343
CCL14 chemokine (C-C motif) ligand 14 1.51263
JMJD1C jumonji domain containing 1C 1.50649
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.50292
KRTAP10-5 keratin associated protein 10-5 1.49297
CTSB cathepsin B 1.48325
GMIP GEM interacting protein 1.4808
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.47747
BOK BCL2-related ovarian killer 1.47502
SETBP1 SET binding protein 1 1.47009
DNAH5 dynein, axonemal, heavy chain 5 1.46879
FAM212B family with sequence similarity 212, member B 1.46491
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.45822
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.45546
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 1.45147
PTGR2 prostaglandin reductase 2 1.45099
CNOT4 CCR4-NOT transcription complex, subunit 4 1.44957
ZNF222 zinc finger protein 222 1.44827
MFN1 mitofusin 1 1.44051
MDK midkine (neurite growth-promoting factor 2) 1.43754
TMED3 transmembrane emp24 protein transport domain containing 3 1.43349
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.42564
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 1.42169
PCDH11Y protocadherin 11 Y-linked 1.42125
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 1.41851
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.41371
FOXB1 forkhead box B1 1.41285
TOM1 target of myb1 (chicken) 1.40987
AANAT aralkylamine N-acetyltransferase 1.40414
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.39438
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 1.38773
TPK1 thiamin pyrophosphokinase 1 1.38339
GPR183 G protein-coupled receptor 183 1.38338
OXCT1 3-oxoacid CoA transferase 1 1.38184
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 1.37927
PXK PX domain containing serine/threonine kinase 1.37906
ADGRG5 adhesion G protein-coupled receptor G5 1.37883
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.37765
STK17A serine/threonine kinase 17a 1.37717
ADGRL2 adhesion G protein-coupled receptor L2 1.37699
KDM5D lysine (K)-specific demethylase 5D 1.37585
OGFR opioid growth factor receptor 1.37242
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.37006
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 1.36343
ZNF721 zinc finger protein 721 1.36067
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.35803
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.35476
ZWILCH zwilch kinetochore protein 1.35403
ADPRHL1 ADP-ribosylhydrolase like 1 1.34958
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.34298
IGFBP6 insulin-like growth factor binding protein 6 1.34097
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 1.33679
AKNA AT-hook transcription factor 1.33211
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 1.33145
CDH7 cadherin 7, type 2 1.32976
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.32705
CDH3 cadherin 3, type 1, P-cadherin (placental) 1.32359
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 1.32037
APOO apolipoprotein O 1.31707
ZNF600 zinc finger protein 600 1.31456
PRICKLE4 prickle homolog 4 (Drosophila) 1.31319
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.30964
ADD1 adducin 1 (alpha) 1.30814
MMP28 matrix metallopeptidase 28 1.30757
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 1.30694
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.3058
EFHD1 EF-hand domain family, member D1 1.30083
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 1.30069
INHBA inhibin, beta A 1.29874
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 1.29063
SLITRK4 SLIT and NTRK-like family, member 4 1.28524
CTR9 CTR9, Paf1/RNA polymerase II complex component 1.28428
ZCCHC9 zinc finger, CCHC domain containing 9 1.27768
FXYD1 FXYD domain containing ion transport regulator 1 1.27568
SPATA8 spermatogenesis associated 8 1.27297
ZNF623 zinc finger protein 623 1.26935
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 1.26395
DLL3 delta-like 3 (Drosophila) 1.2575
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 1.25561
SRSF4 serine/arginine-rich splicing factor 4 1.25375
PCDHA8 protocadherin alpha 8 1.25251
EFCAB3 EF-hand calcium binding domain 3 1.23501
GTF2IRD1 GTF2I repeat domain containing 1 1.23442
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 1.23365
ZNF521 zinc finger protein 521 1.23302
DLK2 delta-like 2 homolog (Drosophila) 1.23298
ANKRD49 ankyrin repeat domain 49 1.2314
ZMYM1 zinc finger, MYM-type 1 1.22736
PHOX2A paired-like homeobox 2a 1.22044
ZNF227 zinc finger protein 227 1.21767
RECQL4 RecQ protein-like 4 1.21641
RGS18 regulator of G-protein signaling 18 1.21131
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.20767
C11ORF45 chromosome 11 open reading frame 45 1.20759
MMP13 matrix metallopeptidase 13 1.20524
FFAR3 free fatty acid receptor 3 1.2046
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.20051
EBF2 early B-cell factor 2 1.19719
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 1.19072
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.18685
CHID1 chitinase domain containing 1 1.18533
POU4F3 POU class 4 homeobox 3 1.18119
KAT2B K(lysine) acetyltransferase 2B 1.18058
DGKH diacylglycerol kinase, eta 1.17927
GPR143 G protein-coupled receptor 143 1.17558
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 1.17466
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.17433
SSH3 slingshot protein phosphatase 3 1.17338
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 1.16854
FN3K fructosamine 3 kinase 1.16715
NME1-NME2 NME1-NME2 readthrough 1.16711
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 1.16703
EIF4A1 eukaryotic translation initiation factor 4A1 1.1657
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 1.16514
TAS2R38 taste receptor, type 2, member 38 1.16116
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 1.15971
POFUT2 protein O-fucosyltransferase 2 1.15766
RPS25 ribosomal protein S25 1.15742
ATF4 activating transcription factor 4 1.15482
RLF rearranged L-myc fusion 1.15342
ILF3 interleukin enhancer binding factor 3, 90kDa 1.15329
COL8A1 collagen, type VIII, alpha 1 1.15242
ZFX zinc finger protein, X-linked 1.15015
DNASE2B deoxyribonuclease II beta 1.15005
STX19 syntaxin 19 1.14867
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.14845
MTM1 myotubularin 1 1.14729
CERS5 ceramide synthase 5 1.14534
GUCA1A guanylate cyclase activator 1A (retina) 1.14436
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.14273
DTX3L deltex 3 like, E3 ubiquitin ligase 1.13705
OCM oncomodulin 1.13411
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.13254
QDPR quinoid dihydropteridine reductase 1.12807
CDH20 cadherin 20, type 2 1.12591
EFNA2 ephrin-A2 1.12583
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.1241
TMPRSS5 transmembrane protease, serine 5 1.12381
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.12121
RPS11 ribosomal protein S11 1.11813
MAPK14 mitogen-activated protein kinase 14 1.11186
S100A7A S100 calcium binding protein A7A 1.10983
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.10654
ZNF672 zinc finger protein 672 1.10538
TAS2R10 taste receptor, type 2, member 10 1.10338
VRK3 vaccinia related kinase 3 1.09953
EIF6 eukaryotic translation initiation factor 6 1.09453
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.09236
FER fer (fps/fes related) tyrosine kinase 1.09122
DEGS2 delta(4)-desaturase, sphingolipid 2 1.09031
TMED6 transmembrane emp24 protein transport domain containing 6 1.08823
SLC30A9 solute carrier family 30 (zinc transporter), member 9 1.08582
ST7 suppression of tumorigenicity 7 1.08553
ARHGAP26 Rho GTPase activating protein 26 1.08501
DIAPH2 diaphanous-related formin 2 1.08162
ZNF433 zinc finger protein 433 1.08158
XPR1 xenotropic and polytropic retrovirus receptor 1 1.08131
ZNF611 zinc finger protein 611 1.07672
PCDHB14 protocadherin beta 14 1.07408
FCRL5 Fc receptor-like 5 1.07306
LAPTM4A lysosomal protein transmembrane 4 alpha 1.0721
PLA2G4B phospholipase A2, group IVB (cytosolic) 1.0713
PVRL4 poliovirus receptor-related 4 1.06956
GJB1 gap junction protein, beta 1, 32kDa 1.06914
GTF2A1L general transcription factor IIA, 1-like 1.06911
NKIRAS2 NFKB inhibitor interacting Ras-like 2 1.06799
MAP3K8 mitogen-activated protein kinase kinase kinase 8 1.06363
ONECUT1 one cut homeobox 1 1.05793
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 1.05667
EIF3H eukaryotic translation initiation factor 3, subunit H 1.05658
GSR glutathione reductase 1.05157
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.05002
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 1.04927
CALML4 calmodulin-like 4 1.04794
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 1.04626
GMPR guanosine monophosphate reductase 1.04387
TSLP thymic stromal lymphopoietin 1.04349
CCL19 chemokine (C-C motif) ligand 19 1.04254
KAT2A K(lysine) acetyltransferase 2A 1.04067
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 1.03243
FMNL1 formin-like 1 1.03195
PARP14 poly (ADP-ribose) polymerase family, member 14 1.0316
RHOT2 ras homolog family member T2 1.03035
PLA2G2E phospholipase A2, group IIE 1.02466
DDHD2 DDHD domain containing 2 1.02292
CETP cholesteryl ester transfer protein, plasma 1.02212
MCM6 minichromosome maintenance complex component 6 1.02193
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.02052
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 1.01898
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 1.01556
ELMO3 engulfment and cell motility 3 1.01464
SIX6 SIX homeobox 6 1.01322
SRPR signal recognition particle receptor (docking protein) 1.01197
EMD emerin 1.00476

decreased fitness

Symbol Name Standardized Value
OAT ornithine aminotransferase -3.51078
THADA thyroid adenoma associated -3.40982
CLEC4D C-type lectin domain family 4, member D -3.13689
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.74841
IGFBP5 insulin-like growth factor binding protein 5 -2.56698
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -2.55201
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -2.41882
RCOR3 REST corepressor 3 -2.40096
OR8S1 olfactory receptor, family 8, subfamily S, member 1 -2.3948
CALCR calcitonin receptor -2.34849
ZNF581 zinc finger protein 581 -2.32438
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.31111
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional) -2.19284
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 -2.17654
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 -2.17175
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2 -2.14578
NR1H2 nuclear receptor subfamily 1, group H, member 2 -2.14324
TSC22D2 TSC22 domain family, member 2 -2.13903
SERHL serine hydrolase-like (pseudogene) -2.13411
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -2.10648
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 -2.10593
MYLIP myosin regulatory light chain interacting protein -2.09885
PTDSS1 phosphatidylserine synthase 1 -2.05563
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -2.05227
CD59 CD59 molecule, complement regulatory protein -2.04466
RFC1 replication factor C (activator 1) 1, 145kDa -2.01056
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -2.00997
SP4 Sp4 transcription factor -2.00739
CHRD chordin -1.9282
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -1.911
KCTD8 potassium channel tetramerization domain containing 8 -1.8959
SOX9 SRY (sex determining region Y)-box 9 -1.89573
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase -1.89254
GNPAT glyceronephosphate O-acyltransferase -1.88957
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -1.88566
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.88532
ADIPOR1 adiponectin receptor 1 -1.86866
GUCY2C guanylate cyclase 2C -1.86159
GPR75 G protein-coupled receptor 75 -1.85469
TPTE transmembrane phosphatase with tensin homology -1.84193
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -1.82142
FAT2 FAT atypical cadherin 2 -1.80605
LYAR Ly1 antibody reactive -1.80518
M6PR mannose-6-phosphate receptor (cation dependent) -1.78954
PPT2 palmitoyl-protein thioesterase 2 -1.77262
SYNJ2 synaptojanin 2 -1.76929
APLP1 amyloid beta (A4) precursor-like protein 1 -1.76543
MAP3K11 mitogen-activated protein kinase kinase kinase 11 -1.75381
BMPR1A bone morphogenetic protein receptor, type IA -1.75203
DTNB dystrobrevin, beta -1.74857
SNW1 SNW domain containing 1 -1.74721
CABLES1 Cdk5 and Abl enzyme substrate 1 -1.74207
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -1.73893
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -1.73051
RAP1B RAP1B, member of RAS oncogene family -1.73003
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1 -1.72571
LIMS1 LIM and senescent cell antigen-like domains 1 -1.72033
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -1.70468
CKS2 CDC28 protein kinase regulatory subunit 2 -1.68902
ZNF174 zinc finger protein 174 -1.68303
CX3CR1 chemokine (C-X3-C motif) receptor 1 -1.6692
KHSRP KH-type splicing regulatory protein -1.66739
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) -1.6603
HIST1H2AB histone cluster 1, H2ab -1.65227
OR56B1 olfactory receptor, family 56, subfamily B, member 1 -1.64811
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -1.64468
DHRS4 dehydrogenase/reductase (SDR family) member 4 -1.64441
LDHA lactate dehydrogenase A -1.62221
INS-IGF2 INS-IGF2 readthrough -1.62031
ZNF322 zinc finger protein 322 -1.62028
PTBP1 polypyrimidine tract binding protein 1 -1.61885
TBX3 T-box 3 -1.59246
OTX2 orthodenticle homeobox 2 -1.58871
BRAF B-Raf proto-oncogene, serine/threonine kinase -1.57206
CTCF CCCTC-binding factor (zinc finger protein) -1.56963
ELP3 elongator acetyltransferase complex subunit 3 -1.55997
HOXB6 homeobox B6 -1.55366
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 -1.54523
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) -1.53691
PLAGL1 pleiomorphic adenoma gene-like 1 -1.53158
NR1H3 nuclear receptor subfamily 1, group H, member 3 -1.52606
PPP1R16A protein phosphatase 1, regulatory subunit 16A -1.51172
ZNF624 zinc finger protein 624 -1.49843
CABP4 calcium binding protein 4 -1.49818
HIST1H2AK histone cluster 1, H2ak -1.49365
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 -1.49148
BCL7A B-cell CLL/lymphoma 7A -1.48779
NEIL2 nei endonuclease VIII-like 2 (E. coli) -1.47737
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 -1.46894
HMMR hyaluronan-mediated motility receptor (RHAMM) -1.45796
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.43556
CLEC3B C-type lectin domain family 3, member B -1.43351
RPL5 ribosomal protein L5 -1.42605
PGK2 phosphoglycerate kinase 2 -1.42601
GPRC5C G protein-coupled receptor, class C, group 5, member C -1.42581
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -1.42453
BNC2 basonuclin 2 -1.42105
SAG S-antigen; retina and pineal gland (arrestin) -1.41902
ZNF273 zinc finger protein 273 -1.41747
ICOS inducible T-cell co-stimulator -1.41682
GJA4 gap junction protein, alpha 4, 37kDa -1.41352
CD4 CD4 molecule -1.40009
BTF3 basic transcription factor 3 -1.37614
GATAD2A GATA zinc finger domain containing 2A -1.37394
ZMAT2 zinc finger, matrin-type 2 -1.3735
ALPPL2 alkaline phosphatase, placental-like 2 -1.37206
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -1.3717
RDH10 retinol dehydrogenase 10 (all-trans) -1.36519
RBBP6 retinoblastoma binding protein 6 -1.36472
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -1.36079
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 -1.35858
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -1.35687
ABHD13 abhydrolase domain containing 13 -1.35463
LIG1 ligase I, DNA, ATP-dependent -1.35415
IL2RB interleukin 2 receptor, beta -1.3466
MDH1 malate dehydrogenase 1, NAD (soluble) -1.3457
IFNA17 interferon, alpha 17 -1.34392
COPS8 COP9 signalosome subunit 8 -1.34242
YAP1 Yes-associated protein 1 -1.34023
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -1.33387
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -1.33245
ZNF462 zinc finger protein 462 -1.33186
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.32867
ACO2 aconitase 2, mitochondrial -1.32339
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 -1.31378
ZNF239 zinc finger protein 239 -1.31284
MAPK1 mitogen-activated protein kinase 1 -1.30894
CPA1 carboxypeptidase A1 (pancreatic) -1.30868
PRKD3 protein kinase D3 -1.30328
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -1.30325
PHF3 PHD finger protein 3 -1.29069
DTX2 deltex 2, E3 ubiquitin ligase -1.29028
PDE1A phosphodiesterase 1A, calmodulin-dependent -1.28985
OR1S1 olfactory receptor, family 1, subfamily S, member 1 (gene/pseudogene) -1.28939
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -1.28804
CTRL chymotrypsin-like -1.28723
SERTAD3 SERTA domain containing 3 -1.28436
DUSP18 dual specificity phosphatase 18 -1.28213
POT1 protection of telomeres 1 -1.27799
FETUB fetuin B -1.2712
TMPRSS11D transmembrane protease, serine 11D -1.26986
DLAT dihydrolipoamide S-acetyltransferase -1.26482
IRX5 iroquois homeobox 5 -1.26373
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -1.25008
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -1.24902
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.24839
BCL2L1 BCL2-like 1 -1.24138
IGFBP4 insulin-like growth factor binding protein 4 -1.24114
IL7R interleukin 7 receptor -1.23912
ZFHX3 zinc finger homeobox 3 -1.23884
ADK adenosine kinase -1.23727
PRKCQ protein kinase C, theta -1.23533
OAZ1 ornithine decarboxylase antizyme 1 -1.23531
MNAT1 MNAT CDK-activating kinase assembly factor 1 -1.23334
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -1.23111
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -1.22904
RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) -1.22851
E2F3 E2F transcription factor 3 -1.22505
USP30 ubiquitin specific peptidase 30 -1.22501
EMX2 empty spiracles homeobox 2 -1.22423
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -1.22394
HIC1 hypermethylated in cancer 1 -1.22312
GYS2 glycogen synthase 2 (liver) -1.21836
MITF microphthalmia-associated transcription factor -1.20788
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -1.20397
P3H2 prolyl 3-hydroxylase 2 -1.20371
FKBP1A FK506 binding protein 1A, 12kDa -1.19876
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa -1.19787
PHKG1 phosphorylase kinase, gamma 1 (muscle) -1.19216
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -1.18756
RAB1B RAB1B, member RAS oncogene family -1.18414
TRAFD1 TRAF-type zinc finger domain containing 1 -1.18318
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.18024
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.18002
ZNF138 zinc finger protein 138 -1.17842
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -1.17717
GRAP GRB2-related adaptor protein -1.17573
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 -1.16956
DDR2 discoidin domain receptor tyrosine kinase 2 -1.16574
LRMP lymphoid-restricted membrane protein -1.15967
PITX3 paired-like homeodomain 3 -1.15819
CKM creatine kinase, muscle -1.15553
HMOX2 heme oxygenase 2 -1.15405
GFOD1 glucose-fructose oxidoreductase domain containing 1 -1.15388
PDE4DIP phosphodiesterase 4D interacting protein -1.15338
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -1.15291
UBE3B ubiquitin protein ligase E3B -1.15187
RPL34 ribosomal protein L34 -1.14517
PVR poliovirus receptor -1.1431
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -1.14025
PHF1 PHD finger protein 1 -1.13992
POR P450 (cytochrome) oxidoreductase -1.13805
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -1.13029
RSPO3 R-spondin 3 -1.12393
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -1.11758
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase -1.11323
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.10878
SKIL SKI-like proto-oncogene -1.10742
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -1.09733
TRPM6 transient receptor potential cation channel, subfamily M, member 6 -1.0972
EPC1 enhancer of polycomb homolog 1 (Drosophila) -1.09432
RHOG ras homolog family member G -1.09401
POU3F4 POU class 3 homeobox 4 -1.09195
HIST1H2AL histone cluster 1, H2al -1.08968
HPR haptoglobin-related protein -1.08819
ZSCAN4 zinc finger and SCAN domain containing 4 -1.08675
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -1.08289
SIRPA signal-regulatory protein alpha -1.08263
TUBD1 tubulin, delta 1 -1.07898
PKN3 protein kinase N3 -1.07495
NRL neural retina leucine zipper -1.07472
ZNF407 zinc finger protein 407 -1.07466
GPR27 G protein-coupled receptor 27 -1.07317
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -1.07288
DPP9 dipeptidyl-peptidase 9 -1.06948
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 -1.06928
KDM3B lysine (K)-specific demethylase 3B -1.06898
SAFB scaffold attachment factor B -1.0677
HOXA10 homeobox A10 -1.06601
ZIK1 zinc finger protein interacting with K protein 1 -1.064
DRD3 dopamine receptor D3 -1.06137
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -1.05884
UBAC2 UBA domain containing 2 -1.05753
SLC39A13 solute carrier family 39 (zinc transporter), member 13 -1.05403
MC5R melanocortin 5 receptor -1.05349
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough -1.05092
SSTR1 somatostatin receptor 1 -1.05058
CHRNG cholinergic receptor, nicotinic, gamma (muscle) -1.04524
NR3C2 nuclear receptor subfamily 3, group C, member 2 -1.04232
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 -1.04062
RGS17 regulator of G-protein signaling 17 -1.03997
MLH1 mutL homolog 1 -1.03695
NOS2 nitric oxide synthase 2, inducible -1.03381
MMP27 matrix metallopeptidase 27 -1.03306
BTF3L4 basic transcription factor 3-like 4 -1.0312
HIST1H2AG histone cluster 1, H2ag -1.02758
COX11 COX11 cytochrome c oxidase copper chaperone -1.02662
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -1.02356
CPM carboxypeptidase M -1.02322
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -1.0225
ZFYVE16 zinc finger, FYVE domain containing 16 -1.02201
DEFA3 defensin, alpha 3, neutrophil-specific -1.01978
CCT2 chaperonin containing TCP1, subunit 2 (beta) -1.01803
PRKY protein kinase, Y-linked, pseudogene -1.01713
SNRPG small nuclear ribonucleoprotein polypeptide G -1.01646
PMF1-BGLAP PMF1-BGLAP readthrough -1.01507
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -1.01495
NMBR neuromedin B receptor -1.01493
RNF13 ring finger protein 13 -1.01175
DMBT1 deleted in malignant brain tumors 1 -1.00933
TPMT thiopurine S-methyltransferase -1.00896
HNF1A HNF1 homeobox A -1.00885
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -1.00752
FUS FUS RNA binding protein -1.00446
NCOA3 nuclear receptor coactivator 3 -1.00271