SW1710 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma, transitional cell (Cell Line Ontology, CLO_0009213)
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Genes

344 genes with high or low expression in SW1710 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
WTAP Wilms tumor 1 associated protein 2.74637
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 2.67822
KALRN kalirin, RhoGEF kinase 2.22625
EVC Ellis van Creveld protein 2.21806
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.21271
VCAM1 vascular cell adhesion molecule 1 2.21158
STAT1 signal transducer and activator of transcription 1, 91kDa 2.1811
KL klotho 2.17861
SEPT2 septin 2 2.10104
CXCL6 chemokine (C-X-C motif) ligand 6 2.07863
CRYZ crystallin, zeta (quinone reductase) 2.04075
PBLD phenazine biosynthesis-like protein domain containing 2.02736
ITM2B integral membrane protein 2B 1.99733
BET1 Bet1 golgi vesicular membrane trafficking protein 1.9934
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 1.98171
ACSL4 acyl-CoA synthetase long-chain family member 4 1.88976
GGT1 gamma-glutamyltransferase 1 1.86931
FXYD2 FXYD domain containing ion transport regulator 2 1.8568
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 1.85528
BICC1 BicC family RNA binding protein 1 1.85257
NDFIP1 Nedd4 family interacting protein 1 1.83011
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.81935
GNG11 guanine nucleotide binding protein (G protein), gamma 11 1.8141
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 1.80595
HABP2 hyaluronan binding protein 2 1.8056
RELN reelin 1.79337
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 1.79065
HNF1B HNF1 homeobox B 1.79048
MALT1 MALT1 paracaspase 1.7518
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 1.7338
HBP1 HMG-box transcription factor 1 1.71795
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 1.68197
NPC1 Niemann-Pick disease, type C1 1.67889
ARHGAP1 Rho GTPase activating protein 1 1.67576
HAVCR1 hepatitis A virus cellular receptor 1 1.65625
AQP9 aquaporin 9 1.62793
PDZK1IP1 PDZK1 interacting protein 1 1.62652
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.61343
CTSC cathepsin C 1.61103
GLS glutaminase 1.60578
CXCL5 chemokine (C-X-C motif) ligand 5 1.60505
ITGAV integrin, alpha V 1.59999
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.59781
CRYAB crystallin, alpha B 1.59433
UBE2E3 ubiquitin-conjugating enzyme E2E 3 1.59154
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 1.58868
CLEC4E C-type lectin domain family 4, member E 1.58803
SIM1 single-minded family bHLH transcription factor 1 1.58289
FHOD3 formin homology 2 domain containing 3 1.5754
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.56992
SAA4 serum amyloid A4, constitutive 1.56114
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.55002
HSPA12A heat shock 70kDa protein 12A 1.54556
TGOLN2 trans-golgi network protein 2 1.53791
CXCL12 chemokine (C-X-C motif) ligand 12 1.53727
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 1.53139
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.53046
CPD carboxypeptidase D 1.52796
TP53BP2 tumor protein p53 binding protein 2 1.50282
NFE2L2 nuclear factor, erythroid 2-like 2 1.49642
RBPMS RNA binding protein with multiple splicing 1.49515
HOXA9 homeobox A9 1.4934
PDZK1 PDZ domain containing 1 1.47966
SLC17A2 solute carrier family 17, member 2 1.47749
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.47618
SOD2 superoxide dismutase 2, mitochondrial 1.46639
UGCG UDP-glucose ceramide glucosyltransferase 1.46551
SAA1 serum amyloid A1 1.46154
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.45323
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.44282
LRRC61 leucine rich repeat containing 61 1.43188
CDH16 cadherin 16, KSP-cadherin 1.43016
NIT2 nitrilase family, member 2 1.4264
TPK1 thiamin pyrophosphokinase 1 1.42564
CHRDL1 chordin-like 1 1.42454
VCAN versican 1.42438
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 1.42056

low expression

Symbol Name Standardized Value
THRAP3 thyroid hormone receptor associated protein 3 -3.53538
LTBP4 latent transforming growth factor beta binding protein 4 -3.32053
MYO15A myosin XVA -3.08897
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -3.07262
MTMR7 myotubularin related protein 7 -2.96762
PLAC4 placenta-specific 4 -2.79111
TTN titin -2.77685
MMRN2 multimerin 2 -2.75364
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 -2.75293
KCTD15 potassium channel tetramerization domain containing 15 -2.73226
ADD2 adducin 2 (beta) -2.71579
GPR182 G protein-coupled receptor 182 -2.64068
OGN osteoglycin -2.61487
CA1 carbonic anhydrase I -2.53282
TAOK1 TAO kinase 1 -2.5259
PAK1IP1 PAK1 interacting protein 1 -2.47979
ALPL alkaline phosphatase, liver/bone/kidney -2.47174
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.44914
PER1 period circadian clock 1 -2.37182
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 -2.36892
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -2.35667
PIPOX pipecolic acid oxidase -2.35315
EPB41 erythrocyte membrane protein band 4.1 -2.34675
HEPH hephaestin -2.33087
SGK3 serum/glucocorticoid regulated kinase family, member 3 -2.31558
PADI4 peptidyl arginine deiminase, type IV -2.30434
TM7SF2 transmembrane 7 superfamily member 2 -2.30027
LOC57399 uncharacterized gastric protein ZA52P -2.29677
PTPRB protein tyrosine phosphatase, receptor type, B -2.28163
TSSK2 testis-specific serine kinase 2 -2.27173
SYT1 synaptotagmin I -2.26606
CHD8 chromodomain helicase DNA binding protein 8 -2.26094
LINC00652 long intergenic non-protein coding RNA 652 -2.25105
EXOSC9 exosome component 9 -2.25068
ZNF749 zinc finger protein 749 -2.2422
NFRKB nuclear factor related to kappaB binding protein -2.23283
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 -2.19113
SPARCL1 SPARC-like 1 (hevin) -2.18979
CNTD2 cyclin N-terminal domain containing 2 -2.16825
DRP2 dystrophin related protein 2 -2.15572
F9 coagulation factor IX -2.15448
CALML4 calmodulin-like 4 -2.15193
INTS7 integrator complex subunit 7 -2.14516
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) -2.1431
ZNF415 zinc finger protein 415 -2.11079
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 -2.10957
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.09911
ETV7 ets variant 7 -2.09727
CCNT1 cyclin T1 -2.08355
CALML3 calmodulin-like 3 -2.08093
NOX3 NADPH oxidase 3 -2.07667
CTRL chymotrypsin-like -2.07045
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -2.06909
BRCA2 breast cancer 2, early onset -2.05327
SYN3 synapsin III -2.04029
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -2.03573
SEPP1 selenoprotein P, plasma, 1 -2.03493
TTLL5 tubulin tyrosine ligase-like family member 5 -2.03238
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) -2.03158
LEFTY1 left-right determination factor 1 -2.02659
OPRM1 opioid receptor, mu 1 -2.00694
CD247 CD247 molecule -2.00658
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 -1.99966
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -1.99503
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -1.9878
SIX3 SIX homeobox 3 -1.98021
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.97878
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -1.97873
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 -1.97297
FYB FYN binding protein -1.95866
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -1.94975
AKAP8L A kinase (PRKA) anchor protein 8-like -1.93583
FRMPD1 FERM and PDZ domain containing 1 -1.92905
ELSPBP1 epididymal sperm binding protein 1 -1.92758
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -1.92712
CRYBB2 crystallin, beta B2 -1.92648
GATA2 GATA binding protein 2 -1.92144
KCTD20 potassium channel tetramerization domain containing 20 -1.91005
ANKRD11 ankyrin repeat domain 11 -1.9044
CD207 CD207 molecule, langerin -1.90343
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -1.90186
CLIC2 chloride intracellular channel 2 -1.90008
SPRR1A small proline-rich protein 1A -1.89948
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -1.89545
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -1.89451
ELF5 E74-like factor 5 (ets domain transcription factor) -1.89226
GJB3 gap junction protein, beta 3, 31kDa -1.88708
MMP25 matrix metallopeptidase 25 -1.88285
SRP54 signal recognition particle 54kDa -1.88259
SNW1 SNW domain containing 1 -1.87783
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -1.87536
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.8713
MED6 mediator complex subunit 6 -1.86844
CIDEB cell death-inducing DFFA-like effector b -1.86668
LAMA4 laminin, alpha 4 -1.85954
PMP2 peripheral myelin protein 2 -1.85122
FGF21 fibroblast growth factor 21 -1.85028
HIST1H4C histone cluster 1, H4c -1.8486
SPON1 spondin 1, extracellular matrix protein -1.84375
STXBP6 syntaxin binding protein 6 (amisyn) -1.83935
ABT1 activator of basal transcription 1 -1.83446
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -1.83423
ACSBG1 acyl-CoA synthetase bubblegum family member 1 -1.83217
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -1.82782
PARP2 poly (ADP-ribose) polymerase 2 -1.82545
VGF VGF nerve growth factor inducible -1.81936
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -1.80811
NXPH4 neurexophilin 4 -1.80545
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -1.79974
PRSS1 protease, serine, 1 (trypsin 1) -1.79631
NXPE4 neurexophilin and PC-esterase domain family, member 4 -1.79495
FSHR follicle stimulating hormone receptor -1.78791
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.78076
ASPN asporin -1.77243
ZNF550 zinc finger protein 550 -1.77005
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -1.76916
PDIA2 protein disulfide isomerase family A, member 2 -1.76619
KLHL1 kelch-like family member 1 -1.76549
MSX2 msh homeobox 2 -1.76165
IRF4 interferon regulatory factor 4 -1.75337
NR5A2 nuclear receptor subfamily 5, group A, member 2 -1.74815
CCL23 chemokine (C-C motif) ligand 23 -1.74589
ASCC2 activating signal cointegrator 1 complex subunit 2 -1.73329
CDKN2A cyclin-dependent kinase inhibitor 2A -1.72989
DHODH dihydroorotate dehydrogenase (quinone) -1.72451
DENND2A DENN/MADD domain containing 2A -1.72329
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -1.70794
CELF2 CUGBP, Elav-like family member 2 -1.70618
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) -1.70545
HPX hemopexin -1.70537
CDHR2 cadherin-related family member 2 -1.70324
DHPS deoxyhypusine synthase -1.70238
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -1.69378
LGALS14 lectin, galactoside-binding, soluble, 14 -1.69374
TMEM35 transmembrane protein 35 -1.69142
AFM afamin -1.69124
RBMS3 RNA binding motif, single stranded interacting protein 3 -1.68651
FHL5 four and a half LIM domains 5 -1.68378
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -1.67754
CAMK2D calcium/calmodulin-dependent protein kinase II delta -1.67741
DNAI2 dynein, axonemal, intermediate chain 2 -1.67258
MARK3 MAP/microtubule affinity-regulating kinase 3 -1.66938
TJP3 tight junction protein 3 -1.66833
MARS methionyl-tRNA synthetase -1.66698
OR7A5 olfactory receptor, family 7, subfamily A, member 5 -1.6659
PRSS21 protease, serine, 21 (testisin) -1.66492
CPN2 carboxypeptidase N, polypeptide 2 -1.66443
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 -1.6633
ZMYM5 zinc finger, MYM-type 5 -1.66204
MYBBP1A MYB binding protein (P160) 1a -1.6611
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -1.65746
APOB apolipoprotein B -1.65229
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 -1.65221
KRT31 keratin 31, type I -1.65089
FRZB frizzled-related protein -1.64737
ARCN1 archain 1 -1.64622
CEP85 centrosomal protein 85kDa -1.63836
DAZL deleted in azoospermia-like -1.63194
CCDC59 coiled-coil domain containing 59 -1.63168
SHANK1 SH3 and multiple ankyrin repeat domains 1 -1.62584
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -1.62522
TLR6 toll-like receptor 6 -1.62142
NOTCH4 notch 4 -1.62119
BHLHB9 basic helix-loop-helix domain containing, class B, 9 -1.61822
SMCP sperm mitochondria-associated cysteine-rich protein -1.61701
HIST1H2BI histone cluster 1, H2bi -1.61453
ATP10B ATPase, class V, type 10B -1.61315
PTPRJ protein tyrosine phosphatase, receptor type, J -1.61243
SIRAL2 SIR2 antiphage like 2 -1.61031
ACR acrosin -1.60907
CD8A CD8a molecule -1.60703
SRSF5 serine/arginine-rich splicing factor 5 -1.60424
FCHO1 FCH domain only 1 -1.59768
EXOSC8 exosome component 8 -1.59508
BARX2 BARX homeobox 2 -1.59124
EBF2 early B-cell factor 2 -1.59081
EDNRB endothelin receptor type B -1.58887
TBCA tubulin folding cofactor A -1.58542
IMPG2 interphotoreceptor matrix proteoglycan 2 -1.58282
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene -1.58033
MLX MLX, MAX dimerization protein -1.5758
MAST4 microtubule associated serine/threonine kinase family member 4 -1.5748
ARID3B AT rich interactive domain 3B (BRIGHT-like) -1.57129
RFPL2 ret finger protein-like 2 -1.57081
ATXN2 ataxin 2 -1.56994
CST8 cystatin 8 (cystatin-related epididymal specific) -1.56679
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -1.55722
CIDEA cell death-inducing DFFA-like effector a -1.55547
IQGAP2 IQ motif containing GTPase activating protein 2 -1.55158
MTMR12 myotubularin related protein 12 -1.55114
ATXN8OS ATXN8 opposite strand (non-protein coding) -1.54806
NUPL1 nucleoporin like 1 -1.54569
LHX6 LIM homeobox 6 -1.54506
KRT75 keratin 75, type II -1.54426
GAL3ST4 galactose-3-O-sulfotransferase 4 -1.54319
COL11A1 collagen, type XI, alpha 1 -1.5416
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -1.53607
USP12 ubiquitin specific peptidase 12 -1.53488
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 -1.52736
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -1.52682
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -1.52485
MASP2 mannan-binding lectin serine peptidase 2 -1.52351
GRM1 glutamate receptor, metabotropic 1 -1.52069
CLGN calmegin -1.52015
TG thyroglobulin -1.51852
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit -1.5166
PRDM16 PR domain containing 16 -1.5114
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -1.51123
TNIP3 TNFAIP3 interacting protein 3 -1.51068
MRPL46 mitochondrial ribosomal protein L46 -1.50772
STATH statherin -1.50733
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -1.50557
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -1.50398
NAV1 neuron navigator 1 -1.50316
HIST1H2AI histone cluster 1, H2ai -1.49831
DEC1 deleted in esophageal cancer 1 -1.49657
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -1.49626
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -1.49527
SYN1 synapsin I -1.49494
HIST1H3H histone cluster 1, H3h -1.49421
TSHB thyroid stimulating hormone, beta -1.49397
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 -1.49313
HIST2H2AA3 histone cluster 2, H2aa3 -1.49248
LRMP lymphoid-restricted membrane protein -1.49192
RORB RAR-related orphan receptor B -1.48644
ARMCX5 armadillo repeat containing, X-linked 5 -1.48331
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -1.47991
RIN3 Ras and Rab interactor 3 -1.47954
CPB2 carboxypeptidase B2 (plasma) -1.47884
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) -1.47832
WASF3 WAS protein family, member 3 -1.47804
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.47671
NPDC1 neural proliferation, differentiation and control, 1 -1.47541
KIF21B kinesin family member 21B -1.47095
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -1.47058
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -1.4702
F2 coagulation factor II (thrombin) -1.46986
RPL36AL ribosomal protein L36a-like -1.4687
MUSK muscle, skeletal, receptor tyrosine kinase -1.46493
TBX3 T-box 3 -1.4627
POU6F2 POU class 6 homeobox 2 -1.46041
MYB v-myb avian myeloblastosis viral oncogene homolog -1.4592
DOCK5 dedicator of cytokinesis 5 -1.45833
KIAA1654 KIAA1654 protein -1.45609
AIM1L absent in melanoma 1-like -1.45415
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 -1.4521
CDO1 cysteine dioxygenase type 1 -1.44933
LRRC2 leucine rich repeat containing 2 -1.44832
GPR27 G protein-coupled receptor 27 -1.44345
MLNR motilin receptor -1.44105
TXNRD2 thioredoxin reductase 2 -1.43989
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -1.43782
GPRC5D G protein-coupled receptor, class C, group 5, member D -1.4376
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -1.43687
MCAM melanoma cell adhesion molecule -1.43663
ADAM8 ADAM metallopeptidase domain 8 -1.43583
SH2D3C SH2 domain containing 3C -1.43578
IMMT inner membrane protein, mitochondrial -1.43181
DEFA5 defensin, alpha 5, Paneth cell-specific -1.43069
ALOX5AP arachidonate 5-lipoxygenase-activating protein -1.42815
DGKB diacylglycerol kinase, beta 90kDa -1.42774
DCAF13 DDB1 and CUL4 associated factor 13 -1.42529
ZNF208 zinc finger protein 208 -1.42296
CETN1 centrin, EF-hand protein, 1 -1.4222
MYBPC3 myosin binding protein C, cardiac -1.42096
SAP30BP SAP30 binding protein -1.41886
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 -1.4182