SW1783 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: astrocytoma (Cell Line Ontology, CLO_0009191)
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Genes

301 genes with high or low expression in SW1783 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CLOCK clock circadian regulator 3.60177
EXOC1 exocyst complex component 1 3.60177
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 3.59989
SRP72 signal recognition particle 72kDa 3.58802
CEP135 centrosomal protein 135kDa 3.53028
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 3.5172
TMEM165 transmembrane protein 165 3.08444
NAGLU N-acetylglucosaminidase, alpha 2.6337
CHIC2 cysteine-rich hydrophobic domain 2 2.54411
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 2.51366
BMP1 bone morphogenetic protein 1 2.45528
FICD FIC domain containing 2.31624
MAN1B1 mannosidase, alpha, class 1B, member 1 2.28099
LHX5 LIM homeobox 5 2.10779
HEXB hexosaminidase B (beta polypeptide) 2.0721
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 2.02045
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 2.00991
ZNF174 zinc finger protein 174 2.00756
NDP Norrie disease (pseudoglioma) 2.00447
PPAT phosphoribosyl pyrophosphate amidotransferase 1.9768
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.95596
PLXDC1 plexin domain containing 1 1.95013
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.94903
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.94167
TPP1 tripeptidyl peptidase I 1.92783
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 1.87505
BDKRB1 bradykinin receptor B1 1.87332
SLC10A3 solute carrier family 10, member 3 1.87267
FLOT1 flotillin 1 1.86861
G6PC3 glucose 6 phosphatase, catalytic, 3 1.86699
EPHB2 EPH receptor B2 1.86684
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 1.85941
VEGFC vascular endothelial growth factor C 1.84644
CHPF2 chondroitin polymerizing factor 2 1.83916
AP2M1 adaptor-related protein complex 2, mu 1 subunit 1.82791
PAMR1 peptidase domain containing associated with muscle regeneration 1 1.81972
TIMP4 TIMP metallopeptidase inhibitor 4 1.81907
TMEM110 transmembrane protein 110 1.81214
KRT84 keratin 84, type II 1.81044
NRBP1 nuclear receptor binding protein 1 1.80544
PDLIM4 PDZ and LIM domain 4 1.80394
TMEM104 transmembrane protein 104 1.79519
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.7827
IRAK1 interleukin-1 receptor-associated kinase 1 1.77357
SPHK1 sphingosine kinase 1 1.77295
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 1.75257
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.75034
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.7438
AMDHD2 amidohydrolase domain containing 2 1.73526
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.73166
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 1.7315
SIL1 SIL1 nucleotide exchange factor 1.72667
IGFBP7 insulin-like growth factor binding protein 7 1.72351
LIMK1 LIM domain kinase 1 1.72121
S1PR2 sphingosine-1-phosphate receptor 2 1.70611
CLPTM1 cleft lip and palate associated transmembrane protein 1 1.70103
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.7002
CYB561D2 cytochrome b561 family, member D2 1.69948
LAMP1 lysosomal-associated membrane protein 1 1.69905
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 1.6855
UBTD1 ubiquitin domain containing 1 1.68487
POMP proteasome maturation protein 1.6755
POFUT2 protein O-fucosyltransferase 2 1.67199
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.66446
TMEM115 transmembrane protein 115 1.66354
SQSTM1 sequestosome 1 1.65398
P3H1 prolyl 3-hydroxylase 1 1.65094
TM9SF1 transmembrane 9 superfamily member 1 1.64408
PCYT1B phosphate cytidylyltransferase 1, choline, beta 1.64219
MOSPD1 motile sperm domain containing 1 1.64163
GRN granulin 1.64029
CTSA cathepsin A 1.63851
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.63372
B3GAT3 beta-1,3-glucuronyltransferase 3 1.62656
SDF4 stromal cell derived factor 4 1.62636
CELA3B chymotrypsin-like elastase family, member 3B 1.62568
RAMP3 receptor (G protein-coupled) activity modifying protein 3 1.62235
SCAMP4 secretory carrier membrane protein 4 1.62022
GNPDA1 glucosamine-6-phosphate deaminase 1 1.61975
MCOLN1 mucolipin 1 1.61551
LMF2 lipase maturation factor 2 1.61363
RHOC ras homolog family member C 1.61142
ITGA7 integrin, alpha 7 1.60403
TGFB1 transforming growth factor, beta 1 1.6024
CD63 CD63 molecule 1.59734
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.59104
CLCN7 chloride channel, voltage-sensitive 7 1.59076
ELK1 ELK1, member of ETS oncogene family 1.59072
RGS3 regulator of G-protein signaling 3 1.58875
TEX264 testis expressed 264 1.58039
RBBP8 retinoblastoma binding protein 8 1.5701
CENPB centromere protein B, 80kDa 1.5638
ANXA10 annexin A10 1.56326
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.56161
GLB1 galactosidase, beta 1 1.55761
POMT1 protein-O-mannosyltransferase 1 1.55168
NID2 nidogen 2 (osteonidogen) 1.54529
MICA MHC class I polypeptide-related sequence A 1.54367
TCTA T-cell leukemia translocation altered 1.54352
GALNS galactosamine (N-acetyl)-6-sulfatase 1.54327
HCG9 HLA complex group 9 (non-protein coding) 1.53965
NOMO2 NODAL modulator 2 1.53772
CLN5 ceroid-lipofuscinosis, neuronal 5 1.5373
VAC14 Vac14 homolog (S. cerevisiae) 1.52747
STC1 stanniocalcin 1 1.52655
CNTNAP1 contactin associated protein 1 1.51772
FAM50A family with sequence similarity 50, member A 1.51731
CUTA cutA divalent cation tolerance homolog (E. coli) 1.51081
CREB3 cAMP responsive element binding protein 3 1.50665
KRT75 keratin 75, type II 1.50644
CRYBB1 crystallin, beta B1 1.50614
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.4994
CORO2B coronin, actin binding protein, 2B 1.49612
SRD5A3 steroid 5 alpha-reductase 3 1.49348
GFPT2 glutamine-fructose-6-phosphate transaminase 2 1.49339
DFNB31 deafness, autosomal recessive 31 1.4871
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.48071
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.47998
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.47554
HS1BP3 HCLS1 binding protein 3 1.4746
LRRC17 leucine rich repeat containing 17 1.46904
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 1.46604
GMPPB GDP-mannose pyrophosphorylase B 1.46135
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 1.46065
TSSC4 tumor suppressing subtransferable candidate 4 1.45893
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.45707
TSC22D4 TSC22 domain family, member 4 1.45622
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 1.45519
COL4A6 collagen, type IV, alpha 6 1.45502
PKLR pyruvate kinase, liver and RBC 1.45462
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.45455
NCDN neurochondrin 1.45283
TMEM53 transmembrane protein 53 1.44991
FAM3A family with sequence similarity 3, member A 1.44791
MMP3 matrix metallopeptidase 3 1.44772
WBSCR22 Williams Beuren syndrome chromosome region 22 1.44307
CLIP2 CAP-GLY domain containing linker protein 2 1.4422
LAMP2 lysosomal-associated membrane protein 2 1.44208
PRAF2 PRA1 domain family, member 2 1.44191
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 1.44027
TRIP6 thyroid hormone receptor interactor 6 1.43934
POSTN periostin, osteoblast specific factor 1.43855
CAMTA2 calmodulin binding transcription activator 2 1.43487
NEU1 sialidase 1 (lysosomal sialidase) 1.4332
IQSEC2 IQ motif and Sec7 domain 2 1.43085
MOXD1 monooxygenase, DBH-like 1 1.42812
ABHD4 abhydrolase domain containing 4 1.4274
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.42269
MOCS2 molybdenum cofactor synthesis 2 1.41806

low expression

Symbol Name Standardized Value
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -3.53702
REV1 REV1, polymerase (DNA directed) -3.47189
ARMC8 armadillo repeat containing 8 -2.96143
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -2.90703
RFPL3 ret finger protein-like 3 -2.88452
CSDE1 cold shock domain containing E1, RNA-binding -2.86725
SRSF7 serine/arginine-rich splicing factor 7 -2.80098
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -2.76146
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -2.75653
DLD dihydrolipoamide dehydrogenase -2.71482
MOB4 MOB family member 4, phocein -2.5812
CCNT2 cyclin T2 -2.48694
USP10 ubiquitin specific peptidase 10 -2.46097
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.43335
NOS1 nitric oxide synthase 1 (neuronal) -2.41414
ZBTB11 zinc finger and BTB domain containing 11 -2.40175
DBP D site of albumin promoter (albumin D-box) binding protein -2.36413
RPL24 ribosomal protein L24 -2.33604
EGR2 early growth response 2 -2.31213
FAM60A family with sequence similarity 60, member A -2.30469
INTS6 integrator complex subunit 6 -2.30265
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -2.22706
SF3B1 splicing factor 3b, subunit 1, 155kDa -2.19514
RFX7 regulatory factor X, 7 -2.14379
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.13378
ORC4 origin recognition complex, subunit 4 -2.09683
SSB Sjogren syndrome antigen B (autoantigen La) -2.09663
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -2.09471
ZNF195 zinc finger protein 195 -2.06701
TMPO thymopoietin -2.05556
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -2.05313
CREB1 cAMP responsive element binding protein 1 -2.02728
ZC3H15 zinc finger CCCH-type containing 15 -2.01039
GLUD2 glutamate dehydrogenase 2 -1.99312
SEC24B SEC24 family member B -1.98003
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -1.94369
PPIG peptidylprolyl isomerase G (cyclophilin G) -1.93346
RSRC1 arginine/serine-rich coiled-coil 1 -1.92954
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -1.92257
SUMO1 small ubiquitin-like modifier 1 -1.91976
PCNP PEST proteolytic signal containing nuclear protein -1.91569
SRSF9 serine/arginine-rich splicing factor 9 -1.91509
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -1.9106
SIAH2 siah E3 ubiquitin protein ligase 2 -1.90795
RNF13 ring finger protein 13 -1.87772
PCDH7 protocadherin 7 -1.86609
RAD21 RAD21 homolog (S. pombe) -1.86556
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -1.84442
EXOC4 exocyst complex component 4 -1.83631
SBNO1 strawberry notch homolog 1 (Drosophila) -1.83225
CNBP CCHC-type zinc finger, nucleic acid binding protein -1.82421
SART3 squamous cell carcinoma antigen recognized by T cells 3 -1.82255
FNTB farnesyltransferase, CAAX box, beta -1.81728
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -1.81269
MSL2 male-specific lethal 2 homolog (Drosophila) -1.81122
MTF2 metal response element binding transcription factor 2 -1.80538
NR2C1 nuclear receptor subfamily 2, group C, member 1 -1.79987
YIPF4 Yip1 domain family, member 4 -1.78513
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -1.78167
ATR ATR serine/threonine kinase -1.77914
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.77557
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -1.76524
SCAF8 SR-related CTD-associated factor 8 -1.7594
TOPBP1 topoisomerase (DNA) II binding protein 1 -1.75232
CEP97 centrosomal protein 97kDa -1.75014
PIAS1 protein inhibitor of activated STAT, 1 -1.74405
RANBP2 RAN binding protein 2 -1.74277
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -1.74159
RNF10 ring finger protein 10 -1.73331
MTX2 metaxin 2 -1.73204
KALRN kalirin, RhoGEF kinase -1.7222
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -1.71927
HCLS1 hematopoietic cell-specific Lyn substrate 1 -1.70244
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -1.70151
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -1.7001
ADNP activity-dependent neuroprotector homeobox -1.69332
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -1.69068
ZNF552 zinc finger protein 552 -1.68904
ENOSF1 enolase superfamily member 1 -1.68592
PNN pinin, desmosome associated protein -1.68162
CENPQ centromere protein Q -1.68
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -1.67597
WDR45B WD repeat domain 45B -1.67538
CUZD1 CUB and zona pellucida-like domains 1 -1.67417
TPD52 tumor protein D52 -1.66614
MRPL48 mitochondrial ribosomal protein L48 -1.65617
PMEL premelanosome protein -1.64993
RNF44 ring finger protein 44 -1.64603
GPN3 GPN-loop GTPase 3 -1.64271
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -1.64194
GPR75 G protein-coupled receptor 75 -1.64161
KHK ketohexokinase (fructokinase) -1.64111
CLDN8 claudin 8 -1.62949
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -1.62656
IVNS1ABP influenza virus NS1A binding protein -1.62318
PIKFYVE phosphoinositide kinase, FYVE finger containing -1.61584
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.60732
PGGT1B protein geranylgeranyltransferase type I, beta subunit -1.59637
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -1.59575
BTG2 BTG family, member 2 -1.59333
ARL5A ADP-ribosylation factor-like 5A -1.59293
SCAF11 SR-related CTD-associated factor 11 -1.59278
U2SURP U2 snRNP-associated SURP domain containing -1.59197
SOX2 SRY (sex determining region Y)-box 2 -1.58768
PKP4 plakophilin 4 -1.58666
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -1.58419
UBA6 ubiquitin-like modifier activating enzyme 6 -1.5799
FASTKD1 FAST kinase domains 1 -1.57601
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -1.57477
ARID4A AT rich interactive domain 4A (RBP1-like) -1.5731
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit -1.57105
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -1.56762
CCNL1 cyclin L1 -1.56598
METAP2 methionyl aminopeptidase 2 -1.56517
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -1.5556
ZC3H11A zinc finger CCCH-type containing 11A -1.55338
RGS13 regulator of G-protein signaling 13 -1.55149
LIMS2 LIM and senescent cell antigen-like domains 2 -1.55143
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -1.54907
SNX4 sorting nexin 4 -1.5287
ANAPC1 anaphase promoting complex subunit 1 -1.52497
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -1.52062
DEC1 deleted in esophageal cancer 1 -1.51985
INADL InaD-like (Drosophila) -1.51198
WDR61 WD repeat domain 61 -1.51066
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -1.5066
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -1.50342
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.50173
ARID3B AT rich interactive domain 3B (BRIGHT-like) -1.49654
ZC3H7A zinc finger CCCH-type containing 7A -1.49135
LAX1 lymphocyte transmembrane adaptor 1 -1.48634
MRPS22 mitochondrial ribosomal protein S22 -1.47474
KPNA4 karyopherin alpha 4 (importin alpha 3) -1.4739
VRK2 vaccinia related kinase 2 -1.4738
ZNF148 zinc finger protein 148 -1.46101
CEP63 centrosomal protein 63kDa -1.45897
RBM8A RNA binding motif protein 8A -1.45393
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -1.45346
ORC1 origin recognition complex, subunit 1 -1.45168
ARID4B AT rich interactive domain 4B (RBP1-like) -1.44977
HIST1H4A histone cluster 1, H4a -1.43896
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -1.43065
CEP68 centrosomal protein 68kDa -1.4286
PTMA prothymosin, alpha -1.42473
ANAPC10 anaphase promoting complex subunit 10 -1.42412
NCOA2 nuclear receptor coactivator 2 -1.4215
METTL5 methyltransferase like 5 -1.42109
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -1.42094
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing -1.41975
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -1.41963
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -1.41854
GMCL1 germ cell-less, spermatogenesis associated 1 -1.4165