SW48 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

249 genes with high or low expression in SW48 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
GNAT3 guanine nucleotide binding protein, alpha transducing 3 3.60177
CPOX coproporphyrinogen oxidase 3.01802
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 3.00958
KLK7 kallikrein-related peptidase 7 3.00752
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 2.85565
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 2.83438
CD36 CD36 molecule (thrombospondin receptor) 2.78741
OXR1 oxidation resistance 1 2.72194
TMEM106B transmembrane protein 106B 2.7015
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.61447
BMP4 bone morphogenetic protein 4 2.58688
S100A5 S100 calcium binding protein A5 2.57851
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2.53071
YLPM1 YLP motif containing 1 2.50627
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 2.36487
BAMBI BMP and activin membrane-bound inhibitor 2.29111
L2HGDH L-2-hydroxyglutarate dehydrogenase 2.2817
NTSR1 neurotensin receptor 1 (high affinity) 2.27103
TDO2 tryptophan 2,3-dioxygenase 2.2402
MTPAP mitochondrial poly(A) polymerase 2.23518
PDE4B phosphodiesterase 4B, cAMP-specific 2.22482
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 2.21971
MIPEP mitochondrial intermediate peptidase 2.1541
PTPRO protein tyrosine phosphatase, receptor type, O 2.12416
MYO19 myosin XIX 2.08461
SDAD1 SDA1 domain containing 1 2.05159
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 2.0471
ADCK2 aarF domain containing kinase 2 2.03257
TULP2 tubby like protein 2 2.02719
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 2.02086
REST RE1-silencing transcription factor 2.01555
EPHA1 EPH receptor A1 1.98039
IL36R interleukin 36 receptor 1.96497
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.96304
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.92467
INHA inhibin, alpha 1.90987
SMAD7 SMAD family member 7 1.90304
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.9018
SMC5 structural maintenance of chromosomes 5 1.89626
CHPF chondroitin polymerizing factor 1.88399
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.87762
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.87372
POM121 POM121 transmembrane nucleoporin 1.87253
TMEM115 transmembrane protein 115 1.86081
PRR7 proline rich 7 (synaptic) 1.83047
UNG uracil-DNA glycosylase 1.82879
ZMYND11 zinc finger, MYND-type containing 11 1.82262
HSPA8 heat shock 70kDa protein 8 1.81889
QARS glutaminyl-tRNA synthetase 1.81061
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 1.80707
CDCA4 cell division cycle associated 4 1.80106
FAM120A family with sequence similarity 120A 1.79123
IER3 immediate early response 3 1.78901
VSNL1 visinin-like 1 1.76376
RBM28 RNA binding motif protein 28 1.75719
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.75475
XKR8 XK, Kell blood group complex subunit-related family, member 8 1.74699
EEF1G eukaryotic translation elongation factor 1 gamma 1.74067
CEP152 centrosomal protein 152kDa 1.73564
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 1.73168
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.73135
OTUD4 OTU deubiquitinase 4 1.73012
EGR1 early growth response 1 1.72521
GPR15 G protein-coupled receptor 15 1.72242
ADCY3 adenylate cyclase 3 1.72133
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 1.71168
EDAR ectodysplasin A receptor 1.70547
EIF3A eukaryotic translation initiation factor 3, subunit A 1.70375
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.69963
IL5 interleukin 5 1.69757
DPF2 D4, zinc and double PHD fingers family 2 1.69287
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.69112
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 1.68801
NAT10 N-acetyltransferase 10 (GCN5-related) 1.68056
BRD7 bromodomain containing 7 1.67925
HOXB9 homeobox B9 1.67281
NEMF nuclear export mediator factor 1.66609
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.66411
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.66251
PAPOLB poly(A) polymerase beta (testis specific) 1.65868
MST1 macrophage stimulating 1 1.65426
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 1.64554
CDC25A cell division cycle 25A 1.64444
ZNF74 zinc finger protein 74 1.6424
EFCC1 EF-hand and coiled-coil domain containing 1 1.63331
TTC22 tetratricopeptide repeat domain 22 1.63168
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 1.62687
RPL7A ribosomal protein L7a 1.62382
NXPE4 neurexophilin and PC-esterase domain family, member 4 1.61991
F12 coagulation factor XII (Hageman factor) 1.61686
RNF43 ring finger protein 43 1.6131
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2 1.61239
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.61192
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 1.61139
BHMT betaine--homocysteine S-methyltransferase 1.60967
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 1.60947
ZNF174 zinc finger protein 174 1.60852
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.60808
PPBPP2 pro-platelet basic protein pseudogene 2 1.60429
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.59698
MSX2 msh homeobox 2 1.59072
RPS24 ribosomal protein S24 1.57374
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding) 1.56525
MLXIPL MLX interacting protein-like 1.56383
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 1.56041
CDK12 cyclin-dependent kinase 12 1.55298
ACTG1 actin gamma 1 1.54973
MACROD1 MACRO domain containing 1 1.54958
SETD4 SET domain containing 4 1.54861
ANGEL1 angel homolog 1 (Drosophila) 1.53625
ACBD4 acyl-CoA binding domain containing 4 1.53546
GAN gigaxonin 1.51982
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 1.51801
LGALS8 lectin, galactoside-binding, soluble, 8 1.51255
GLS2 glutaminase 2 (liver, mitochondrial) 1.51028
EZR ezrin 1.50952
ETV7 ets variant 7 1.50924
NPM3 nucleophosmin/nucleoplasmin 3 1.50832
TFR2 transferrin receptor 2 1.50659
ZDHHC18 zinc finger, DHHC-type containing 18 1.50195
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.50027
UBXN4 UBX domain protein 4 1.49297
ARL4A ADP-ribosylation factor-like 4A 1.48398
CIRBP cold inducible RNA binding protein 1.48352
GPER1 G protein-coupled estrogen receptor 1 1.47831
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 1.47745
RPL17 ribosomal protein L17 1.47461
DOCK5 dedicator of cytokinesis 5 1.47246
PITX3 paired-like homeodomain 3 1.46953
IFT54 intraflagellar transport 54 1.45413
HPSE heparanase 1.45412
RPL29 ribosomal protein L29 1.44588
MTA1 metastasis associated 1 1.44508
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.4442
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.43107
TNK1 tyrosine kinase, non-receptor, 1 1.42972
AKAP3 A kinase (PRKA) anchor protein 3 1.41847
CELA2A chymotrypsin-like elastase family, member 2A 1.41655

low expression

Symbol Name Standardized Value
FBXL12 F-box and leucine-rich repeat protein 12 -3.49856
LRP12 low density lipoprotein receptor-related protein 12 -3.15578
AGK acylglycerol kinase -3.14701
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.90305
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.66652
TXNDC9 thioredoxin domain containing 9 -2.61613
EID1 EP300 interacting inhibitor of differentiation 1 -2.60124
HLTF helicase-like transcription factor -2.60116
FAM214B family with sequence similarity 214, member B -2.59918
LCMT2 leucine carboxyl methyltransferase 2 -2.58323
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -2.53521
ZNF264 zinc finger protein 264 -2.50741
BTD biotinidase -2.43884
ASB8 ankyrin repeat and SOCS box containing 8 -2.42845
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -2.40626
UST uronyl-2-sulfotransferase -2.39444
KRBOX4 KRAB box domain containing 4 -2.33591
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -2.31984
RWDD2A RWD domain containing 2A -2.26336
PLIN2 perilipin 2 -2.16184
ATRN attractin -2.15109
NIT1 nitrilase 1 -2.12689
ZNF331 zinc finger protein 331 -2.11082
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -2.09147
MPV17 MpV17 mitochondrial inner membrane protein -2.07755
SRD5A3 steroid 5 alpha-reductase 3 -2.07494
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -2.0507
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -2.03277
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -2.02347
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.01802
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.01398
ST7L suppression of tumorigenicity 7 like -1.99144
QKI QKI, KH domain containing, RNA binding -1.9847
HRK harakiri, BCL2 interacting protein -1.96607
DGUOK deoxyguanosine kinase -1.96005
DES desmin -1.95005
TMEM53 transmembrane protein 53 -1.9492
ZFAND6 zinc finger, AN1-type domain 6 -1.92891
ING4 inhibitor of growth family, member 4 -1.92309
EMC3 ER membrane protein complex subunit 3 -1.91681
SEC63 SEC63 homolog (S. cerevisiae) -1.91049
GLRB glycine receptor, beta -1.90111
KRT10 keratin 10, type I -1.90038
C5AR1 complement component 5a receptor 1 -1.89893
ASIC3 acid sensing (proton gated) ion channel 3 -1.89425
GAMT guanidinoacetate N-methyltransferase -1.88087
ZNF415 zinc finger protein 415 -1.86412
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -1.85001
PSG6 pregnancy specific beta-1-glycoprotein 6 -1.83472
TMCO1 transmembrane and coiled-coil domains 1 -1.83132
DOHH deoxyhypusine hydroxylase/monooxygenase -1.82192
ZNF468 zinc finger protein 468 -1.80581
MLH1 mutL homolog 1 -1.78549
EXOC6B exocyst complex component 6B -1.77508
CCDC90B coiled-coil domain containing 90B -1.75188
PCDHGC3 protocadherin gamma subfamily C, 3 -1.74784
PDGFD platelet derived growth factor D -1.73853
MTERF1 mitochondrial transcription termination factor 1 -1.72758
ZNF22 zinc finger protein 22 -1.72401
SMAP1 small ArfGAP 1 -1.71611
ANKRD7 ankyrin repeat domain 7 -1.71108
ELOVL5 ELOVL fatty acid elongase 5 -1.66585
SIRT5 sirtuin 5 -1.66349
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -1.65545
MOCS3 molybdenum cofactor synthesis 3 -1.65427
MLF1 myeloid leukemia factor 1 -1.65231
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) -1.64426
TOX3 TOX high mobility group box family member 3 -1.64359
IL36G interleukin 36, gamma -1.63699
SPATA2 spermatogenesis associated 2 -1.63349
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.63107
PRKACB protein kinase, cAMP-dependent, catalytic, beta -1.62919
TBC1D19 TBC1 domain family, member 19 -1.62826
DAD1 defender against cell death 1 -1.62812
RAP2A RAP2A, member of RAS oncogene family -1.62667
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 -1.62279
LMO1 LIM domain only 1 (rhombotin 1) -1.62131
FAM63A family with sequence similarity 63, member A -1.61951
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -1.61698
UBL5 ubiquitin-like 5 -1.61664
CSF1R colony stimulating factor 1 receptor -1.61593
SOAT1 sterol O-acyltransferase 1 -1.60455
OGFRL1 opioid growth factor receptor-like 1 -1.6006
WDR45B WD repeat domain 45B -1.58077
IFNA10 interferon, alpha 10 -1.57885
PANX1 pannexin 1 -1.57807
PYHIN1 pyrin and HIN domain family, member 1 -1.57506
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -1.57312
MYNN myoneurin -1.57237
BCL2L13 BCL2-like 13 (apoptosis facilitator) -1.56198
ZNF14 zinc finger protein 14 -1.55415
ULK1 unc-51 like autophagy activating kinase 1 -1.54564
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 -1.52568
CTSL cathepsin L -1.51705
MAPK10 mitogen-activated protein kinase 10 -1.50746
MYH10 myosin, heavy chain 10, non-muscle -1.50173
TNP2 transition protein 2 (during histone to protamine replacement) -1.49963
WDR5B WD repeat domain 5B -1.4993
C1D C1D nuclear receptor corepressor -1.49153
SERINC3 serine incorporator 3 -1.4906
ZNF551 zinc finger protein 551 -1.48991
WDR78 WD repeat domain 78 -1.47889
DYNLRB1 dynein, light chain, roadblock-type 1 -1.45751
MCTS1 malignant T cell amplified sequence 1 -1.45535
YPEL5 yippee-like 5 (Drosophila) -1.45391
CCDC53 coiled-coil domain containing 53 -1.44773
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -1.44743
CIAO1 cytosolic iron-sulfur assembly component 1 -1.445
PCSK2 proprotein convertase subtilisin/kexin type 2 -1.43881
MN1 meningioma (disrupted in balanced translocation) 1 -1.43809
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -1.42052