SW480 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

425 gene knockdowns changing fitness of SW480 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
THRA thyroid hormone receptor, alpha 3.07801
CD1C CD1c molecule 2.61024
GMPR guanosine monophosphate reductase 2.56836
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 2.50376
SARDH sarcosine dehydrogenase 2.40052
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 2.37586
HIATL1 hippocampus abundant transcript-like 1 2.37337
ZC3HC1 zinc finger, C3HC-type containing 1 2.3432
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 2.23865
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 2.20992
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.19715
FAM35A family with sequence similarity 35, member A 2.19059
KRT23 keratin 23, type I 2.18097
RPS3 ribosomal protein S3 2.14851
MYNN myoneurin 2.12512
MRC2 mannose receptor, C type 2 2.11698
ODC1 ornithine decarboxylase 1 2.11203
RFC4 replication factor C (activator 1) 4, 37kDa 2.1078
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 2.07381
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 2.06187
UBTF upstream binding transcription factor, RNA polymerase I 2.03899
PRKY protein kinase, Y-linked, pseudogene 2.03019
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 1.96809
HRAS Harvey rat sarcoma viral oncogene homolog 1.9622
STRN4 striatin, calmodulin binding protein 4 1.95081
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.92398
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 1.90773
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.89141
RAD17 RAD17 homolog (S. pombe) 1.8812
USP21 ubiquitin specific peptidase 21 1.87109
NIT1 nitrilase 1 1.81331
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.78398
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.76401
TRIM23 tripartite motif containing 23 1.7302
MAPK9 mitogen-activated protein kinase 9 1.72404
VCP valosin containing protein 1.68243
SOD1 superoxide dismutase 1, soluble 1.6648
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 1.6571
FDX1 ferredoxin 1 1.65689
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 1.6435
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.58855
FRMPD2 FERM and PDZ domain containing 2 1.58645
AURKB aurora kinase B 1.58482
OIP5 Opa interacting protein 5 1.58379
MATR3 matrin 3 1.57817
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 1.57773
NUP214 nucleoporin 214kDa 1.56754
KRT3 keratin 3, type II 1.5533
RGS4 regulator of G-protein signaling 4 1.552
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.54942
AADAT aminoadipate aminotransferase 1.53781
POU2F3 POU class 2 homeobox 3 1.53261
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.52875
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.52289
RARS arginyl-tRNA synthetase 1.51589
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 1.51521
TXNRD1 thioredoxin reductase 1 1.51406
ZNF124 zinc finger protein 124 1.50724
SRRM1 serine/arginine repetitive matrix 1 1.50684
UBA3 ubiquitin-like modifier activating enzyme 3 1.49652
GADD45G growth arrest and DNA-damage-inducible, gamma 1.49381
NRL neural retina leucine zipper 1.48512
CSF1 colony stimulating factor 1 (macrophage) 1.48076
MAST2 microtubule associated serine/threonine kinase 2 1.47942
NRF1 nuclear respiratory factor 1 1.47174
BARHL1 BarH-like homeobox 1 1.46419
NAMPT nicotinamide phosphoribosyltransferase 1.45989
ZNF423 zinc finger protein 423 1.4586
AHCY adenosylhomocysteinase 1.45063
SEC13 SEC13 homolog (S. cerevisiae) 1.44671
MAPKBP1 mitogen-activated protein kinase binding protein 1 1.44524
AANAT aralkylamine N-acetyltransferase 1.43749
ZNF462 zinc finger protein 462 1.43581
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 1.43063
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 1.42926
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 1.41676
DHFR dihydrofolate reductase 1.41566
STAT5B signal transducer and activator of transcription 5B 1.41544
NES nestin 1.40153
ISCU iron-sulfur cluster assembly enzyme 1.39759
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.39657
MUC7 mucin 7, secreted 1.3804
ST7 suppression of tumorigenicity 7 1.37397
GTF2I general transcription factor IIi 1.36696
MYL12B myosin, light chain 12B, regulatory 1.36297
MTL5 metallothionein-like 5, testis-specific (tesmin) 1.35255
LPAR4 lysophosphatidic acid receptor 4 1.35172
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.34562
SMC2 structural maintenance of chromosomes 2 1.34477
EFNA2 ephrin-A2 1.34279
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 1.34176
MRPS16 mitochondrial ribosomal protein S16 1.33586
KRT17 keratin 17, type I 1.32624
PPIH peptidylprolyl isomerase H (cyclophilin H) 1.32535
PNP purine nucleoside phosphorylase 1.31104
ACBD3 acyl-CoA binding domain containing 3 1.30837
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.30576
HK3 hexokinase 3 (white cell) 1.30003
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.29736
BMP15 bone morphogenetic protein 15 1.29422
ZNF721 zinc finger protein 721 1.29322
TRIM50 tripartite motif containing 50 1.29298
LOC652119 1.29283
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.29246
INSR insulin receptor 1.29168
GSC goosecoid homeobox 1.29069
ARCN1 archain 1 1.29063
TGFB2 transforming growth factor, beta 2 1.29046
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.27928
RAB3A RAB3A, member RAS oncogene family 1.27007
ZNF35 zinc finger protein 35 1.26944
FAM3C family with sequence similarity 3, member C 1.26861
RHEB Ras homolog enriched in brain 1.26721
TARBP1 TAR (HIV-1) RNA binding protein 1 1.26214
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.26134
SEC62 SEC62 homolog (S. cerevisiae) 1.25714
GJA3 gap junction protein, alpha 3, 46kDa 1.25531
ECD ecdysoneless homolog (Drosophila) 1.25221
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 1.24913
RHOT1 ras homolog family member T1 1.24632
RPTOR regulatory associated protein of MTOR, complex 1 1.24362
BPGM 2,3-bisphosphoglycerate mutase 1.23991
INA internexin neuronal intermediate filament protein, alpha 1.23251
IGLL1 immunoglobulin lambda-like polypeptide 1 1.23177
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.23123
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.23077
TPST2 tyrosylprotein sulfotransferase 2 1.22815
ZMYM1 zinc finger, MYM-type 1 1.22796
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.22751
ADCK1 aarF domain containing kinase 1 1.22209
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 1.22125
PRDM10 PR domain containing 10 1.2204
DLG2 discs, large homolog 2 (Drosophila) 1.21872
OLFML2B olfactomedin-like 2B 1.21642
LOC100506859 1.21396
ANKRD17 ankyrin repeat domain 17 1.2129
RAB7A RAB7A, member RAS oncogene family 1.21259
ZNF860 zinc finger protein 860 1.20877
HIST1H2BM histone cluster 1, H2bm 1.20246
ZNF845 zinc finger protein 845 1.20118
SYT10 synaptotagmin X 1.19748
ZNF497 zinc finger protein 497 1.19176
GJB1 gap junction protein, beta 1, 32kDa 1.19128
H2AFX H2A histone family, member X 1.18548
RBM25 RNA binding motif protein 25 1.18224
EIF3F eukaryotic translation initiation factor 3, subunit F 1.17972
PRDM1 PR domain containing 1, with ZNF domain 1.17877
PTGR2 prostaglandin reductase 2 1.1763
HK2 hexokinase 2 1.17615
MICA MHC class I polypeptide-related sequence A 1.17064
NT5M 5',3'-nucleotidase, mitochondrial 1.16887
KRT18 keratin 18, type I 1.16636
TPM2 tropomyosin 2 (beta) 1.16622
ZNF525 zinc finger protein 525 1.16432
UGDH UDP-glucose 6-dehydrogenase 1.1616
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.16035
IKZF2 IKAROS family zinc finger 2 (Helios) 1.15818
CRNN cornulin 1.15817
ZNF273 zinc finger protein 273 1.15064
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.15026
SLC6A16 solute carrier family 6, member 16 1.1494
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.14759
RNF183 ring finger protein 183 1.14605
AXL AXL receptor tyrosine kinase 1.14561
RRM1 ribonucleotide reductase M1 1.13537
CIAO1 cytosolic iron-sulfur assembly component 1 1.12292
OR8A1 olfactory receptor, family 8, subfamily A, member 1 1.12029
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.11401
TP53BP1 tumor protein p53 binding protein 1 1.11359
MAP3K2 mitogen-activated protein kinase kinase kinase 2 1.11262
PPP1R10 protein phosphatase 1, regulatory subunit 10 1.11118
FCGBP Fc fragment of IgG binding protein 1.11037
TOPBP1 topoisomerase (DNA) II binding protein 1 1.10851
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 1.10561
URM1 ubiquitin related modifier 1 1.1049
TTC23 tetratricopeptide repeat domain 23 1.10405
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 1.10028
DSTYK dual serine/threonine and tyrosine protein kinase 1.09978
CDK2 cyclin-dependent kinase 2 1.09808
RASL10B RAS-like, family 10, member B 1.09493
ZNF611 zinc finger protein 611 1.09479
ERBB2 erb-b2 receptor tyrosine kinase 2 1.09246
AP3M2 adaptor-related protein complex 3, mu 2 subunit 1.09232
STYX serine/threonine/tyrosine interacting protein 1.08754
TRIM60 tripartite motif containing 60 1.08748
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.08582
CADM3 cell adhesion molecule 3 1.08216
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 1.07845
VRK3 vaccinia related kinase 3 1.07578
BRD4 bromodomain containing 4 1.07359
LOC100653162 1.07337
TAS1R1 taste receptor, type 1, member 1 1.07198
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.06868
ELP4 elongator acetyltransferase complex subunit 4 1.06796
F2 coagulation factor II (thrombin) 1.06585
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 1.06461
ZCCHC9 zinc finger, CCHC domain containing 9 1.06331
PARP8 poly (ADP-ribose) polymerase family, member 8 1.06317
YBX1 Y box binding protein 1 1.0623
IKZF5 IKAROS family zinc finger 5 (Pegasus) 1.05927
GEN1 GEN1 Holliday junction 5' flap endonuclease 1.0557
TRIM58 tripartite motif containing 58 1.05288
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.05254
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.0515
DLX6 distal-less homeobox 6 1.05016
ACSL6 acyl-CoA synthetase long-chain family member 6 1.04984
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.04883
RHOQ ras homolog family member Q 1.04865
BRCA1 breast cancer 1, early onset 1.04815
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 1.04546
MAN2B1 mannosidase, alpha, class 2B, member 1 1.04159
ZNF281 zinc finger protein 281 1.04071
KRT7 keratin 7, type II 1.03844
LPCAT2 lysophosphatidylcholine acyltransferase 2 1.03843
EPRS glutamyl-prolyl-tRNA synthetase 1.03299
PQBP1 polyglutamine binding protein 1 1.03217
WFDC5 WAP four-disulfide core domain 5 1.03189
NEK11 NIMA-related kinase 11 1.02688
HOXC5 homeobox C5 1.02568
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 1.02244
BPTF bromodomain PHD finger transcription factor 1.02136
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.02106
U2AF1 U2 small nuclear RNA auxiliary factor 1 1.02038
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 1.01946
CDK19 cyclin-dependent kinase 19 1.01757
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 1.01739
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.01696
ZNF566 zinc finger protein 566 1.01625
STX5 syntaxin 5 1.01614
EYS eyes shut homolog (Drosophila) 1.01504
IL13 interleukin 13 1.01481
C11ORF45 chromosome 11 open reading frame 45 1.01332
PDS5B PDS5 cohesin associated factor B 1.0131
DIDO1 death inducer-obliterator 1 1.01219
IL2RB interleukin 2 receptor, beta 1.00879
CECR1 cat eye syndrome chromosome region, candidate 1 1.00586
DDHD2 DDHD domain containing 2 1.00553
TCEA3 transcription elongation factor A (SII), 3 1.0048
ACOT12 acyl-CoA thioesterase 12 1.00151

decreased fitness

Symbol Name Standardized Value
IL1RAP interleukin 1 receptor accessory protein -3.04202
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -2.82218
RAB11A RAB11A, member RAS oncogene family -2.57763
HNMT histamine N-methyltransferase -2.51271
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -2.45817
LPP LIM domain containing preferred translocation partner in lipoma -2.43586
MMP23A matrix metallopeptidase 23A (pseudogene) -2.23077
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 -2.15114
SLC45A2 solute carrier family 45, member 2 -2.08564
IFI16 interferon, gamma-inducible protein 16 -2.0652
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma -1.94477
POLL polymerase (DNA directed), lambda -1.92805
PTBP3 polypyrimidine tract binding protein 3 -1.8961
IL12A interleukin 12A -1.87788
OGG1 8-oxoguanine DNA glycosylase -1.86395
GPX3 glutathione peroxidase 3 -1.84931
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 -1.81995
PPT1 palmitoyl-protein thioesterase 1 -1.81992
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -1.78554
TMED6 transmembrane emp24 protein transport domain containing 6 -1.77001
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 -1.76927
DERA deoxyribose-phosphate aldolase (putative) -1.74256
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -1.73398
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -1.70701
FZD3 frizzled class receptor 3 -1.69505
ZNF16 zinc finger protein 16 -1.67933
PDE1A phosphodiesterase 1A, calmodulin-dependent -1.67611
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -1.64156
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -1.6284
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 -1.61836
ASRGL1 asparaginase like 1 -1.60822
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -1.60676
CPQ carboxypeptidase Q -1.60275
R3HDM2 R3H domain containing 2 -1.59809
GAL3ST4 galactose-3-O-sulfotransferase 4 -1.56472
RARS2 arginyl-tRNA synthetase 2, mitochondrial -1.55698
IL26 interleukin 26 -1.55456
TEX30 testis expressed 30 -1.53369
SLC16A12 solute carrier family 16, member 12 -1.52412
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) -1.52004
PLXNA4 plexin A4 -1.50592
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -1.49931
OR2T5 olfactory receptor, family 2, subfamily T, member 5 -1.49053
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.48568
NCS1 neuronal calcium sensor 1 -1.47313
PRKCSH protein kinase C substrate 80K-H -1.47217
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -1.46876
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.46875
MATN3 matrilin 3 -1.46592
SLC35A4 solute carrier family 35, member A4 -1.46297
ZNF100 zinc finger protein 100 -1.46152
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.46147
IL17RC interleukin 17 receptor C -1.46089
NGF nerve growth factor (beta polypeptide) -1.45724
CUTC cutC copper transporter -1.45694
PZP pregnancy-zone protein -1.45077
ADGRE3 adhesion G protein-coupled receptor E3 -1.43595
C1QA complement component 1, q subcomponent, A chain -1.41689
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -1.40953
OR4D11 olfactory receptor, family 4, subfamily D, member 11 -1.4005
ZNF585A zinc finger protein 585A -1.39288
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -1.38923
RGS9 regulator of G-protein signaling 9 -1.38726
ABHD14A abhydrolase domain containing 14A -1.37621
PON2 paraoxonase 2 -1.37368
DCHS2 dachsous cadherin-related 2 -1.35833
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -1.35773
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -1.35645
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.35621
MBD6 methyl-CpG binding domain protein 6 -1.35585
ZNF22 zinc finger protein 22 -1.35456
MECP2 methyl CpG binding protein 2 -1.33736
FETUB fetuin B -1.32608
ARL13B ADP-ribosylation factor-like 13B -1.32462
ASPH aspartate beta-hydroxylase -1.3104
IFNA16 interferon, alpha 16 -1.3069
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase -1.30252
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -1.30137
DEC1 deleted in esophageal cancer 1 -1.29724
CELF2 CUGBP, Elav-like family member 2 -1.29335
AIF1L allograft inflammatory factor 1-like -1.28778
GZMM granzyme M (lymphocyte met-ase 1) -1.28728
ARID4A AT rich interactive domain 4A (RBP1-like) -1.28651
KIF1B kinesin family member 1B -1.28217
GBA2 glucosidase, beta (bile acid) 2 -1.27095
OAT ornithine aminotransferase -1.27083
TMX3 thioredoxin-related transmembrane protein 3 -1.26887
MED30 mediator complex subunit 30 -1.26366
DCTN4 dynactin 4 (p62) -1.26331
PEG3 paternally expressed 3 -1.26118
L3MBTL4 l(3)mbt-like 4 (Drosophila) -1.25693
KRT19 keratin 19, type I -1.25005
RHPN2 rhophilin, Rho GTPase binding protein 2 -1.24964
BGLAP bone gamma-carboxyglutamate (gla) protein -1.24549
MAP2K3 mitogen-activated protein kinase kinase 3 -1.24502
FGF21 fibroblast growth factor 21 -1.23927
PRKACG protein kinase, cAMP-dependent, catalytic, gamma -1.2379
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -1.23468
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -1.23102
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -1.22851
BMP6 bone morphogenetic protein 6 -1.22727
ETNK1 ethanolamine kinase 1 -1.22724
FOXE3 forkhead box E3 -1.22435
ADGRF5 adhesion G protein-coupled receptor F5 -1.21279
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) -1.2114
GJA4 gap junction protein, alpha 4, 37kDa -1.20945
AKNA AT-hook transcription factor -1.19493
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -1.19078
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -1.18156
HAL histidine ammonia-lyase -1.17468
XRN2 5'-3' exoribonuclease 2 -1.1712
RAX2 retina and anterior neural fold homeobox 2 -1.16833
ZFP64 ZFP64 zinc finger protein -1.16404
FBXO21 F-box protein 21 -1.16089
HELLS helicase, lymphoid-specific -1.15733
PAQR4 progestin and adipoQ receptor family member IV -1.15589
BRSK1 BR serine/threonine kinase 1 -1.15228
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -1.1383
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -1.13584
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.13409
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -1.13264
MCTS1 malignant T cell amplified sequence 1 -1.1299
BCL7A B-cell CLL/lymphoma 7A -1.12906
PTPRU protein tyrosine phosphatase, receptor type, U -1.12732
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -1.12438
ZNF146 zinc finger protein 146 -1.12203
NPTN neuroplastin -1.11774
HOXA9 homeobox A9 -1.11455
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -1.11323
LPPR1 lipid phosphate phosphatase-related protein type 1 -1.10876
ITPKA inositol-trisphosphate 3-kinase A -1.10791
CASP8AP2 caspase 8 associated protein 2 -1.10481
STRN3 striatin, calmodulin binding protein 3 -1.10066
MID1 midline 1 -1.10043
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 -1.09964
CLDN14 claudin 14 -1.09847
PCCA propionyl CoA carboxylase, alpha polypeptide -1.09831
KRAS Kirsten rat sarcoma viral oncogene homolog -1.09794
SYT7 synaptotagmin VII -1.09692
ICMT isoprenylcysteine carboxyl methyltransferase -1.09492
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -1.09145
KCNIP4 Kv channel interacting protein 4 -1.09045
UBE2H ubiquitin-conjugating enzyme E2H -1.08989
SLC26A9 solute carrier family 26 (anion exchanger), member 9 -1.08464
UBQLNL ubiquilin-like -1.08153
SLA2 Src-like-adaptor 2 -1.08101
LOC729739 peptidylprolyl isomerase A (cyclophilin A) pseudogene -1.07923
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 -1.07735
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -1.07486
COPS8 COP9 signalosome subunit 8 -1.07348
PFN4 profilin family, member 4 -1.06961
RARA retinoic acid receptor, alpha -1.06791
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -1.0674
CXCR2 chemokine (C-X-C motif) receptor 2 -1.06476
NKX2-5 NK2 homeobox 5 -1.06473
ELL elongation factor RNA polymerase II -1.06388
TLR5 toll-like receptor 5 -1.06268
ANOS1 anosmin 1 -1.06234
IFNGR1 interferon gamma receptor 1 -1.0567
ALG1L ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like -1.05333
ABHD10 abhydrolase domain containing 10 -1.05111
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -1.04922
DUSP18 dual specificity phosphatase 18 -1.04042
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -1.04029
RNASE4 ribonuclease, RNase A family, 4 -1.03998
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -1.0397
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -1.03615
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -1.03561
BMP7 bone morphogenetic protein 7 -1.03504
RERG RAS-like, estrogen-regulated, growth inhibitor -1.03474
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -1.02835
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 -1.02717
SQRDL sulfide quinone reductase-like (yeast) -1.02627
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -1.02408
PREPL prolyl endopeptidase-like -1.02378
OR2T1 olfactory receptor, family 2, subfamily T, member 1 -1.02058
PPP1R9A protein phosphatase 1, regulatory subunit 9A -1.02032
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.01178
COG2 component of oligomeric golgi complex 2 -1.01148
THPO thrombopoietin -1.00999
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -1.00738
PGM1 phosphoglucomutase 1 -1.00673
ACO2 aconitase 2, mitochondrial -1.00593
HMSD histocompatibility (minor) serpin domain containing -1.0028
RAB22A RAB22A, member RAS oncogene family -1.00266
CCDC12 coiled-coil domain containing 12 -1.00133