SW626 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human, ovary, adenocarcinoma cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001881)
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Genes

235 genes with high or low expression in SW626 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
FASLG Fas ligand (TNF superfamily, member 6) 3.5338
SCN5A sodium channel, voltage gated, type V alpha subunit 3.14429
RTEL1 regulator of telomere elongation helicase 1 3.13273
BTG4 B-cell translocation gene 4 2.91369
WNT6 wingless-type MMTV integration site family, member 6 2.65456
MALT1 MALT1 paracaspase 2.64882
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.61282
KRT20 keratin 20, type I 2.58643
NRG1 neuregulin 1 2.5572
LHX6 LIM homeobox 6 2.5145
CST5 cystatin D 2.44088
NPC2 Niemann-Pick disease, type C2 2.44063
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.43636
INSIG2 insulin induced gene 2 2.29316
MMP19 matrix metallopeptidase 19 2.26305
PRCP prolylcarboxypeptidase (angiotensinase C) 2.23797
IL23A interleukin 23, alpha subunit p19 2.22635
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.19909
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.19515
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 2.19342
MRPS22 mitochondrial ribosomal protein S22 2.16513
EXPH5 exophilin 5 2.16503
TPX2 TPX2, microtubule-associated 2.13738
SIK2 salt-inducible kinase 2 2.10377
BCL2L1 BCL2-like 1 2.08777
ZBED2 zinc finger, BED-type containing 2 2.04631
RHEB Ras homolog enriched in brain 2.02579
DEFA5 defensin, alpha 5, Paneth cell-specific 1.98791
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 1.96993
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 1.9591
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.9559
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 1.94543
KRT83 keratin 83, type II 1.93999
UBE2C ubiquitin-conjugating enzyme E2C 1.93149
CST1 cystatin SN 1.9252
CKS2 CDC28 protein kinase regulatory subunit 2 1.92189
PDGFB platelet-derived growth factor beta polypeptide 1.91669
BMP4 bone morphogenetic protein 4 1.90757
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 1.9043
ANXA2P3 annexin A2 pseudogene 3 1.88375
VSNL1 visinin-like 1 1.88242
RAB3B RAB3B, member RAS oncogene family 1.8766
CTSV cathepsin V 1.87167
PAM peptidylglycine alpha-amidating monooxygenase 1.87167
SLCO1B3 solute carrier organic anion transporter family, member 1B3 1.85259
GBX2 gastrulation brain homeobox 2 1.83475
MSX1 msh homeobox 1 1.8331
CDCA3 cell division cycle associated 3 1.80833
LRRC42 leucine rich repeat containing 42 1.79241
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 1.78668
LY6G6C lymphocyte antigen 6 complex, locus G6C 1.77178
ARHGAP12 Rho GTPase activating protein 12 1.76084
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 1.73823
RAB30 RAB30, member RAS oncogene family 1.71738
AGTPBP1 ATP/GTP binding protein 1 1.71653
KLK10 kallikrein-related peptidase 10 1.7067
CST7 cystatin F (leukocystatin) 1.70474
TUBB4B tubulin, beta 4B class IVb 1.70354
PAH phenylalanine hydroxylase 1.70185
HYAL2 hyaluronoglucosaminidase 2 1.69898
SORBS1 sorbin and SH3 domain containing 1 1.69549
RAD23B RAD23 homolog B (S. cerevisiae) 1.68489
DEFB126 defensin, beta 126 1.67213
DYNLRB1 dynein, light chain, roadblock-type 1 1.66824
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.66014
SFRP5 secreted frizzled-related protein 5 1.65978
KLHL3 kelch-like family member 3 1.65632
PCSK5 proprotein convertase subtilisin/kexin type 5 1.6557
RBP1 retinol binding protein 1, cellular 1.65048
NGFR nerve growth factor receptor 1.64872
KISS1 KiSS-1 metastasis-suppressor 1.64308
INHBB inhibin, beta B 1.63203
CST3 cystatin C 1.63111
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 1.62363
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.6161
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 1.61255
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.60913
GRM8 glutamate receptor, metabotropic 8 1.58889
TRERF1 transcriptional regulating factor 1 1.58483
NEBL nebulette 1.56468
CST2 cystatin SA 1.56017
GPSM2 G-protein signaling modulator 2 1.5593
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 1.55411
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.5538
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 1.55302
TH tyrosine hydroxylase 1.55096
ANXA1 annexin A1 1.54588
HSPB3 heat shock 27kDa protein 3 1.54279
STK39 serine threonine kinase 39 1.53132
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 1.53057
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 1.52958
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 1.52927
RLBP1 retinaldehyde binding protein 1 1.52664
TUB tubby bipartite transcription factor 1.52508
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.51411
RGS9 regulator of G-protein signaling 9 1.5122
ZNF510 zinc finger protein 510 1.5113
AVP arginine vasopressin 1.50532
NELL2 NEL-like 2 (chicken) 1.5006
MOSPD1 motile sperm domain containing 1 1.49524
ZIC4 Zic family member 4 1.49251
CCNB1 cyclin B1 1.4896
CST4 cystatin S 1.48496
BAMBI BMP and activin membrane-bound inhibitor 1.48316
TSC22D1 TSC22 domain family, member 1 1.48197
CD9 CD9 molecule 1.47857
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.47699
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.46547
DCLK1 doublecortin-like kinase 1 1.46399
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 1.45963
AHCY adenosylhomocysteinase 1.45054
CDKN3 cyclin-dependent kinase inhibitor 3 1.45023
PRAMEF5 PRAME family member 5 1.44751
BIK BCL2-interacting killer (apoptosis-inducing) 1.44565
TREML2 triggering receptor expressed on myeloid cells-like 2 1.44263
JPH2 junctophilin 2 1.43793
UGP2 UDP-glucose pyrophosphorylase 2 1.43403
EMC6 ER membrane protein complex subunit 6 1.42978
CALB1 calbindin 1, 28kDa 1.42741
PKP2 plakophilin 2 1.42703
NCAPG2 non-SMC condensin II complex, subunit G2 1.42102
OXSM 3-oxoacyl-ACP synthase, mitochondrial 1.42076
NDP Norrie disease (pseudoglioma) 1.41643

low expression

Symbol Name Standardized Value
PKD1 polycystic kidney disease 1 (autosomal dominant) -3.53698
KIAA0430 KIAA0430 -3.09143
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) -2.50092
BMP15 bone morphogenetic protein 15 -2.46427
DDIT4 DNA-damage-inducible transcript 4 -2.38478
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.36817
SYNGR1 synaptogyrin 1 -2.34789
MORF4L1 mortality factor 4 like 1 -2.34026
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) -2.3271
MUTYH mutY homolog -2.28385
ATF6B activating transcription factor 6 beta -2.23191
CHD9 chromodomain helicase DNA binding protein 9 -2.20741
EPN2 epsin 2 -2.18351
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -2.18152
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 -2.13597
ZNF304 zinc finger protein 304 -2.0849
SGSH N-sulfoglucosamine sulfohydrolase -2.07112
GOSR1 golgi SNAP receptor complex member 1 -2.06891
MON2 MON2 homolog (S. cerevisiae) -2.05031
ELF2 E74-like factor 2 (ets domain transcription factor) -2.0313
PCDHGB5 protocadherin gamma subfamily B, 5 -2.00684
RIT1 Ras-like without CAAX 1 -2.00397
VPS13B vacuolar protein sorting 13 homolog B (yeast) -1.99543
TRIB2 tribbles pseudokinase 2 -1.9854
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -1.97678
RLF rearranged L-myc fusion -1.96459
CEP350 centrosomal protein 350kDa -1.95457
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -1.92416
EVL Enah/Vasp-like -1.90018
KIAA0195 KIAA0195 -1.87677
FLCN folliculin -1.85519
NFE2L1 nuclear factor, erythroid 2-like 1 -1.84975
PLA2G15 phospholipase A2, group XV -1.84957
ETFDH electron-transferring-flavoprotein dehydrogenase -1.84027
CHD3 chromodomain helicase DNA binding protein 3 -1.83793
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -1.83722
MAPK3 mitogen-activated protein kinase 3 -1.83688
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -1.83217
ZNF276 zinc finger protein 276 -1.8239
FBN1 fibrillin 1 -1.81739
FAM3A family with sequence similarity 3, member A -1.80315
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.79525
AVPR1A arginine vasopressin receptor 1A -1.7708
PTX3 pentraxin 3, long -1.7654
WSB1 WD repeat and SOCS box containing 1 -1.75979
TPK1 thiamin pyrophosphokinase 1 -1.731
CPEB3 cytoplasmic polyadenylation element binding protein 3 -1.70605
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa -1.70463
NOTCH4 notch 4 -1.69382
SCUBE2 signal peptide, CUB domain, EGF-like 2 -1.68588
TP53I11 tumor protein p53 inducible protein 11 -1.67988
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -1.67857
ADAR adenosine deaminase, RNA-specific -1.67856
PHF21A PHD finger protein 21A -1.66881
AAK1 AP2 associated kinase 1 -1.6678
MDFIC MyoD family inhibitor domain containing -1.66631
GYG2 glycogenin 2 -1.66256
ZFHX4 zinc finger homeobox 4 -1.65771
RCOR3 REST corepressor 3 -1.6559
RFPL3S RFPL3 antisense -1.65292
BTN3A1 butyrophilin, subfamily 3, member A1 -1.64461
MTX1 metaxin 1 -1.6417
COL5A2 collagen, type V, alpha 2 -1.63466
USP27X ubiquitin specific peptidase 27, X-linked -1.62313
USP32 ubiquitin specific peptidase 32 -1.60784
FAM135A family with sequence similarity 135, member A -1.60426
FHOD1 formin homology 2 domain containing 1 -1.60217
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) -1.59724
DEDD death effector domain containing -1.59478
SEC24D SEC24 family member D -1.59282
ZBTB48 zinc finger and BTB domain containing 48 -1.59228
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -1.59079
SEC31A SEC31 homolog A (S. cerevisiae) -1.5701
CRY2 cryptochrome circadian clock 2 -1.56132
APOA1 apolipoprotein A-I -1.55945
COL9A2 collagen, type IX, alpha 2 -1.55912
GRIP2 glutamate receptor interacting protein 2 -1.54936
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -1.53563
RAD51B RAD51 paralog B -1.52902
FOXP1 forkhead box P1 -1.52869
KLF7 Kruppel-like factor 7 (ubiquitous) -1.52685
ARNT aryl hydrocarbon receptor nuclear translocator -1.5219
MTMR3 myotubularin related protein 3 -1.5187
GTF2A1 general transcription factor IIA, 1, 19/37kDa -1.5083
SULF1 sulfatase 1 -1.50827
FUZ fuzzy planar cell polarity protein -1.50208
TFEB transcription factor EB -1.50149
SCPEP1 serine carboxypeptidase 1 -1.50098
TNXB tenascin XB -1.49841
FRMD4B FERM domain containing 4B -1.49833
HDLBP high density lipoprotein binding protein -1.49348
EXOC7 exocyst complex component 7 -1.48407
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -1.47417
JAM2 junctional adhesion molecule 2 -1.47245
ANKRD46 ankyrin repeat domain 46 -1.46356
CDK10 cyclin-dependent kinase 10 -1.46049
STK16 serine/threonine kinase 16 -1.45552
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene -1.45194
SPATA6 spermatogenesis associated 6 -1.44826
TRAFD1 TRAF-type zinc finger domain containing 1 -1.44447
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -1.43831
ADAM17 ADAM metallopeptidase domain 17 -1.4382
ASIC3 acid sensing (proton gated) ion channel 3 -1.43786
CTBS chitobiase, di-N-acetyl- -1.4354
CLK2 CDC-like kinase 2 -1.43452
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -1.43286
N4BP1 NEDD4 binding protein 1 -1.43236
WDR7 WD repeat domain 7 -1.42646
TTC31 tetratricopeptide repeat domain 31 -1.42583
CHIC2 cysteine-rich hydrophobic domain 2 -1.42534
CD226 CD226 molecule -1.42525
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -1.41743