SW684 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: fibrosarcoma (Cell Line Ontology, CLO_0009198)
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Genes

359 genes with high or low expression in SW684 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SMTN smoothelin 3.15947
AKAP3 A kinase (PRKA) anchor protein 3 2.96508
TRIOBP TRIO and F-actin binding protein 2.54913
PEF1 penta-EF-hand domain containing 1 2.46463
STEAP3 STEAP family member 3, metalloreductase 2.41646
GLB1L galactosidase, beta 1-like 2.36845
VAC14 Vac14 homolog (S. cerevisiae) 2.30186
CTSK cathepsin K 2.27167
FKBP1A FK506 binding protein 1A, 12kDa 2.21717
GTF2H5 general transcription factor IIH, polypeptide 5 2.15692
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.15237
TUBGCP2 tubulin, gamma complex associated protein 2 2.13811
SFXN3 sideroflexin 3 2.10346
ILK integrin-linked kinase 2.01766
PNPLA3 patatin-like phospholipase domain containing 3 2.01365
MYH9 myosin, heavy chain 9, non-muscle 1.98141
ARHGAP22 Rho GTPase activating protein 22 1.96614
MAP7D1 MAP7 domain containing 1 1.96302
FLNA filamin A, alpha 1.94279
TMEM109 transmembrane protein 109 1.88462
LRRC15 leucine rich repeat containing 15 1.84721
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 1.83264
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 1.82773
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 1.82765
TLN1 talin 1 1.79213
HPCAL1 hippocalcin-like 1 1.78472
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.77821
SPHK1 sphingosine kinase 1 1.77554
ANGPTL4 angiopoietin-like 4 1.7726
PKM pyruvate kinase, muscle 1.77204
PEA15 phosphoprotein enriched in astrocytes 15 1.73731
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.73717
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 1.72642
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 1.71862
CAPNS1 calpain, small subunit 1 1.71295
FAM86C1 family with sequence similarity 86, member C1 1.71226
BMP1 bone morphogenetic protein 1 1.68497
STAG1 stromal antigen 1 1.68178
AOX1 aldehyde oxidase 1 1.68029
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 1.65954
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.65468
KIAA1644 KIAA1644 1.6465
TFE3 transcription factor binding to IGHM enhancer 3 1.62363
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.61457
TRPC4 transient receptor potential cation channel, subfamily C, member 4 1.61425
NOTCH2NL notch 2 N-terminal like 1.60067
MPV17 MpV17 mitochondrial inner membrane protein 1.59469
CD4 CD4 molecule 1.57505
RIN1 Ras and Rab interactor 1 1.57403
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.56548
NEFL neurofilament, light polypeptide 1.55657
TMEM158 transmembrane protein 158 (gene/pseudogene) 1.55465
KRBOX4 KRAB box domain containing 4 1.54972
METRN meteorin, glial cell differentiation regulator 1.54047
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1.53492
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.53213
SYNC syncoilin, intermediate filament protein 1.53079
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 1.53047
COL6A2 collagen, type VI, alpha 2 1.52598
PLK3 polo-like kinase 3 1.51589
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 1.50297
HSPG2 heparan sulfate proteoglycan 2 1.50247
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.49832
NPC2 Niemann-Pick disease, type C2 1.49757
RNH1 ribonuclease/angiogenin inhibitor 1 1.48979
TRIM8 tripartite motif containing 8 1.48857
TMEM14B transmembrane protein 14B 1.48459
NAV3 neuron navigator 3 1.48397
MVP major vault protein 1.48146
GBP1 guanylate binding protein 1, interferon-inducible 1.4796
TSPAN5 tetraspanin 5 1.47246
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.47014
LAMP2 lysosomal-associated membrane protein 2 1.46714
JUN jun proto-oncogene 1.46421
HLA-G major histocompatibility complex, class I, G 1.45401
PER3 period circadian clock 3 1.44991
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 1.44697
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.44595
QSOX1 quiescin Q6 sulfhydryl oxidase 1 1.44198
HOMER3 homer scaffolding protein 3 1.44185
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 1.44177
ACO1 aconitase 1, soluble 1.44056
PSG2 pregnancy specific beta-1-glycoprotein 2 1.43314
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.43141
TAGLN2 transgelin 2 1.4278
ACTN1 actinin, alpha 1 1.42633
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.42356

low expression

Symbol Name Standardized Value
SPAG16 sperm associated antigen 16 -3.51878
BCAS4 breast carcinoma amplified sequence 4 -3.35581
STK38L serine/threonine kinase 38 like -3.28249
ADAM7 ADAM metallopeptidase domain 7 -3.26819
MVB12B multivesicular body subunit 12B -3.21383
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -3.14069
SCCPDH saccharopine dehydrogenase (putative) -3.04365
PRO2964 uncharacterized protein PRO2964 -2.94269
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 -2.84238
PLA2R1 phospholipase A2 receptor 1, 180kDa -2.76216
CNR2 cannabinoid receptor 2 (macrophage) -2.70156
ASS1 argininosuccinate synthase 1 -2.66243
GCH1 GTP cyclohydrolase 1 -2.63762
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -2.61161
TMEM147 transmembrane protein 147 -2.60159
ESD esterase D -2.60116
SLC25A38 solute carrier family 25, member 38 -2.57034
GCLC glutamate-cysteine ligase, catalytic subunit -2.54458
MDFI MyoD family inhibitor -2.50482
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.49299
PDGFRL platelet-derived growth factor receptor-like -2.45544
CCR6 chemokine (C-C motif) receptor 6 -2.41043
LHX5 LIM homeobox 5 -2.39335
MANBA mannosidase, beta A, lysosomal -2.36604
MYH14 myosin, heavy chain 14, non-muscle -2.36339
KLHL3 kelch-like family member 3 -2.29549
OCLM oculomedin -2.28024
ICOSLG inducible T-cell co-stimulator ligand -2.25562
DSC3 desmocollin 3 -2.22626
DHCR7 7-dehydrocholesterol reductase -2.21027
CEL carboxyl ester lipase -2.20379
DHCR24 24-dehydrocholesterol reductase -2.19951
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -2.19743
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -2.18298
DCP2 decapping mRNA 2 -2.17354
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -2.16941
LUZP4 leucine zipper protein 4 -2.16444
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 -2.15806
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -2.15567
DPP4 dipeptidyl-peptidase 4 -2.15535
RGS16 regulator of G-protein signaling 16 -2.13261
SNAP25 synaptosomal-associated protein, 25kDa -2.12971
SCRN1 secernin 1 -2.09376
SYT17 synaptotagmin XVII -2.09332
FBXO41 F-box protein 41 -2.08407
GOLPH3L golgi phosphoprotein 3-like -2.08222
PGGT1B protein geranylgeranyltransferase type I, beta subunit -2.08208
SACK1E scaffolding CK1 anchoring protein E -2.08062
PDE3A phosphodiesterase 3A, cGMP-inhibited -2.07482
LDLR low density lipoprotein receptor -2.06297
EHD3 EH-domain containing 3 -2.04112
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -2.03707
RIMS3 regulating synaptic membrane exocytosis 3 -2.03114
NYNRIN NYN domain and retroviral integrase containing -2.02585
RSF1 remodeling and spacing factor 1 -2.02495
CTSC cathepsin C -2.02028
LOC647070 uncharacterized LOC647070 -2.00617
HHEX hematopoietically expressed homeobox -1.99001
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -1.98726
AQP3 aquaporin 3 (Gill blood group) -1.98545
TGIF2 TGFB-induced factor homeobox 2 -1.98177
SCIN scinderin -1.97566
OPLAH 5-oxoprolinase (ATP-hydrolysing) -1.96707
ERMP1 endoplasmic reticulum metallopeptidase 1 -1.96591
PAH phenylalanine hydroxylase -1.96075
RAB31 RAB31, member RAS oncogene family -1.95674
BID BH3 interacting domain death agonist -1.94769
TBC1D22B TBC1 domain family, member 22B -1.94523
FGFR4 fibroblast growth factor receptor 4 -1.94255
CNR1 cannabinoid receptor 1 (brain) -1.93732
FZD3 frizzled class receptor 3 -1.93105
PTCH2 patched 2 -1.9184
PTPRG protein tyrosine phosphatase, receptor type, G -1.91208
SARS2 seryl-tRNA synthetase 2, mitochondrial -1.90241
L3MBTL1 l(3)mbt-like 1 (Drosophila) -1.89954
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 -1.8995
KLHL23 kelch-like family member 23 -1.89807
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -1.88479
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated -1.88476
REN renin -1.88474
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -1.88243
KERA keratocan -1.8819
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -1.88058
MAP3K9 mitogen-activated protein kinase kinase kinase 9 -1.87857
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -1.87341
TREML2 triggering receptor expressed on myeloid cells-like 2 -1.86524
VLDLR very low density lipoprotein receptor -1.8597
GGT5 gamma-glutamyltransferase 5 -1.85161
SCN9A sodium channel, voltage gated, type IX alpha subunit -1.84802
GLRB glycine receptor, beta -1.84712
LOC390998 ribosomal protein L10 pseudogene -1.84388
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 -1.84033
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -1.8279
CADM3 cell adhesion molecule 3 -1.82545
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.82159
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 -1.8134
CPLX3 complexin 3 -1.80628
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -1.80584
IFNW1 interferon, omega 1 -1.80317
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -1.80305
LMO1 LIM domain only 1 (rhombotin 1) -1.80238
PCCB propionyl CoA carboxylase, beta polypeptide -1.79324
PARD6A par-6 family cell polarity regulator alpha -1.79299
LY75 lymphocyte antigen 75 -1.78893
ALLC allantoicase -1.78889
MARCKSL1 MARCKS-like 1 -1.7873
ASNS asparagine synthetase (glutamine-hydrolyzing) -1.78682
LHCGR luteinizing hormone/choriogonadotropin receptor -1.78602
DDIT4 DNA-damage-inducible transcript 4 -1.77854
CCR10 chemokine (C-C motif) receptor 10 -1.77178
TMEM121 transmembrane protein 121 -1.76547
EFNA1 ephrin-A1 -1.76378
NT5M 5',3'-nucleotidase, mitochondrial -1.75507
MMP13 matrix metallopeptidase 13 -1.75007
BAIAP2L2 BAI1-associated protein 2-like 2 -1.74953
TLX3 T-cell leukemia homeobox 3 -1.73574
HOXB7 homeobox B7 -1.73524
RAP1GAP RAP1 GTPase activating protein -1.72863
GAP43 growth associated protein 43 -1.72861
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -1.72803
MOBP myelin-associated oligodendrocyte basic protein -1.72755
MED26 mediator complex subunit 26 -1.71937
JAG2 jagged 2 -1.71925
SDC3 syndecan 3 -1.71641
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -1.71524
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -1.71381
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -1.71019
CD302 CD302 molecule -1.70936
LGALS8 lectin, galactoside-binding, soluble, 8 -1.70902
BNC1 basonuclin 1 -1.70872
ZNF80 zinc finger protein 80 -1.70714
TONSL tonsoku-like, DNA repair protein -1.7013
LINC00652 long intergenic non-protein coding RNA 652 -1.69968
STEAP4 STEAP family member 4 -1.69765
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -1.6961
INTS1 integrator complex subunit 1 -1.68937
SH2D1A SH2 domain containing 1A -1.68898
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -1.68872
ZBTB3 zinc finger and BTB domain containing 3 -1.68859
EGLN3 egl-9 family hypoxia-inducible factor 3 -1.68533
PRR5 proline rich 5 (renal) -1.68484
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 -1.67894
SEC14L3 SEC14-like 3 (S. cerevisiae) -1.67883
HEYL hes-related family bHLH transcription factor with YRPW motif-like -1.67411
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 -1.6731
HMHA1 histocompatibility (minor) HA-1 -1.66767
CCAR2 cell cycle and apoptosis regulator 2 -1.66568
RPS3 ribosomal protein S3 -1.66287
FCHO1 FCH domain only 1 -1.66279
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit -1.66268
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase -1.66154
OLFM1 olfactomedin 1 -1.65824
MSMB microseminoprotein, beta- -1.65815
HSF1 heat shock transcription factor 1 -1.65714
GYG2 glycogenin 2 -1.65678
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -1.65676
NKAIN1 Na+/K+ transporting ATPase interacting 1 -1.65578
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 -1.64768
PRSS1 protease, serine, 1 (trypsin 1) -1.64454
SHMT1 serine hydroxymethyltransferase 1 (soluble) -1.6426
PDE2A phosphodiesterase 2A, cGMP-stimulated -1.63931
IL17A interleukin 17A -1.63888
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa -1.6378
SCN2B sodium channel, voltage gated, type II beta subunit -1.6377
SCYL3 SCY1-like 3 (S. cerevisiae) -1.62747
OPRK1 opioid receptor, kappa 1 -1.62644
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -1.62591
IQSEC1 IQ motif and Sec7 domain 1 -1.61671
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 -1.61267
CA4 carbonic anhydrase IV -1.60833
CCNK cyclin K -1.60534
GLYAT glycine-N-acyltransferase -1.60419
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) -1.60375
CCDC88C coiled-coil domain containing 88C -1.60335
SCN1B sodium channel, voltage gated, type I beta subunit -1.60051
CD24 CD24 molecule -1.59846
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -1.5969
BANK1 B-cell scaffold protein with ankyrin repeats 1 -1.59572
RGS13 regulator of G-protein signaling 13 -1.582
LEFTY2 left-right determination factor 2 -1.58197
SAMHD1 SAM domain and HD domain 1 -1.58007
ZNF202 zinc finger protein 202 -1.57997
HIST1H2BL histone cluster 1, H2bl -1.57964
WNT2B wingless-type MMTV integration site family, member 2B -1.57634
EDA2R ectodysplasin A2 receptor -1.57492
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -1.57368
NRXN1 neurexin 1 -1.57287
EFNA2 ephrin-A2 -1.57137
TNMD tenomodulin -1.56709
PODXL2 podocalyxin-like 2 -1.56542
CNTRL centriolin -1.56492
RFPL2 ret finger protein-like 2 -1.56491
SCARA3 scavenger receptor class A, member 3 -1.55884
EMILIN2 elastin microfibril interfacer 2 -1.55648
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 -1.55379
CST6 cystatin E/M -1.5525
SDK2 sidekick cell adhesion molecule 2 -1.55129
HIST1H2BJ histone cluster 1, H2bj -1.54944
CLDN1 claudin 1 -1.54819
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -1.54815
MAPK11 mitogen-activated protein kinase 11 -1.5443
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -1.54128
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -1.54097
PLXNA3 plexin A3 -1.53839
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -1.53443
TP53 tumor protein p53 -1.53384
SLC38A1 solute carrier family 38, member 1 -1.53213
RAB4A RAB4A, member RAS oncogene family -1.52941
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -1.52078
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -1.5197
GPR50 G protein-coupled receptor 50 -1.51856
BAG2 BCL2-associated athanogene 2 -1.51563
MRPL48 mitochondrial ribosomal protein L48 -1.51341
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 -1.51314
GRIK3 glutamate receptor, ionotropic, kainate 3 -1.50839
ABLIM1 actin binding LIM protein 1 -1.50747
CD38 CD38 molecule -1.50691
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) -1.50663
SELL selectin L -1.50495
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator -1.50314
FXN frataxin -1.50192
AP3B2 adaptor-related protein complex 3, beta 2 subunit -1.50074
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -1.49647
SRY sex determining region Y -1.49526
USP3 ubiquitin specific peptidase 3 -1.49345
KRT20 keratin 20, type I -1.49278
CCDC81 coiled-coil domain containing 81 -1.48999
SPTBN2 spectrin, beta, non-erythrocytic 2 -1.48956
RASL12 RAS-like, family 12 -1.48718
XKR8 XK, Kell blood group complex subunit-related family, member 8 -1.48696
NIT2 nitrilase family, member 2 -1.48323
ETNK2 ethanolamine kinase 2 -1.48226
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 -1.47957
SYT5 synaptotagmin V -1.479
SFXN1 sideroflexin 1 -1.47781
AGRP agouti related neuropeptide -1.47712
CROCC ciliary rootlet coiled-coil, rootletin -1.47626
VCP valosin containing protein -1.47033
RGS11 regulator of G-protein signaling 11 -1.46643
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -1.46594
GJA1 gap junction protein, alpha 1, 43kDa -1.46179
TMED1 transmembrane emp24 protein transport domain containing 1 -1.46075
PHGDH phosphoglycerate dehydrogenase -1.45992
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -1.45541
OCA2 oculocutaneous albinism II -1.45298
CCNE1 cyclin E1 -1.44934
DOT1L DOT1-like histone H3K79 methyltransferase -1.4492
MYH4 myosin, heavy chain 4, skeletal muscle -1.44835
LAMC3 laminin, gamma 3 -1.44649
ZNF695 zinc finger protein 695 -1.44204
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -1.44096
BATF3 basic leucine zipper transcription factor, ATF-like 3 -1.43978
PRSS21 protease, serine, 21 (testisin) -1.43646
NXPE4 neurexophilin and PC-esterase domain family, member 4 -1.43597
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -1.43524
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -1.43438
DEF6 differentially expressed in FDCP 6 homolog (mouse) -1.4312
CP ceruloplasmin (ferroxidase) -1.42997
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -1.42881
TSPAN15 tetraspanin 15 -1.42857
SPHAR S-phase response (cyclin related) -1.42497
GIMAP4 GTPase, IMAP family member 4 -1.42443
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -1.42199
HCG9 HLA complex group 9 (non-protein coding) -1.42102
TBX21 T-box 21 -1.41967
PLA2G2F phospholipase A2, group IIF -1.41837
ADGRG6 adhesion G protein-coupled receptor G6 -1.41811
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -1.41725
MYO1D myosin ID -1.41715
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -1.41686
RAB3B RAB3B, member RAS oncogene family -1.41662
TEX13B testis expressed 13B -1.41613