SW780 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: transitional cell carcinoma (Cell Line Ontology, CLO_0009199)
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Genes

282 genes with high or low expression in SW780 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 3.60177
UPK1A uroplakin 1A 3.60177
REN renin 3.60177
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 3.59209
THADA thyroid adenoma associated 3.4762
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.28834
TRAK1 trafficking protein, kinesin binding 1 2.95375
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.73634
SEPT8 septin 8 2.65024
SASH1 SAM and SH3 domain containing 1 2.58758
UPK2 uroplakin 2 2.57108
FER1L4 fer-1-like family member 4, pseudogene (functional) 2.55324
DTX4 deltex 4, E3 ubiquitin ligase 2.50531
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 2.48075
BLCAP bladder cancer associated protein 2.45715
UPK3B uroplakin 3B 2.32643
CPNE1 copine I 2.21621
ETV7 ets variant 7 2.21567
CROT carnitine O-octanoyltransferase 2.20853
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.19419
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.1684
CNGA1 cyclic nucleotide gated channel alpha 1 2.15967
BCAS1 breast carcinoma amplified sequence 1 2.15875
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.12119
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase 2.11957
PKN2 protein kinase N2 2.09093
GNPDA1 glucosamine-6-phosphate deaminase 1 2.05972
SRPX2 sushi-repeat containing protein, X-linked 2 2.05952
EML2 echinoderm microtubule associated protein like 2 2.05512
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 2.04797
VRK3 vaccinia related kinase 3 2.0349
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.0312
ZNF446 zinc finger protein 446 2.01648
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 2.01469
GSTM1 glutathione S-transferase mu 1 1.97795
PADI3 peptidyl arginine deiminase, type III 1.95389
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.95222
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.92193
LIPE lipase, hormone-sensitive 1.91742
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 1.91255
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 1.8966
CNOT3 CCR4-NOT transcription complex, subunit 3 1.89499
ZNF224 zinc finger protein 224 1.89072
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.8883
TRIM31 tripartite motif containing 31 1.85464
BCAP31 B-cell receptor-associated protein 31 1.85009
FBLN1 fibulin 1 1.84331
AGO4 argonaute RISC catalytic component 4 1.83995
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.83719
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.83293
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.82868
RHBG Rh family, B glycoprotein (gene/pseudogene) 1.81637
PRKD2 protein kinase D2 1.81547
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.81402
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 1.80971
CEL carboxyl ester lipase 1.80614
SCNN1B sodium channel, non voltage gated 1 beta subunit 1.7937
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 1.79354
SSH3 slingshot protein phosphatase 3 1.78645
ZNF219 zinc finger protein 219 1.78235
JPH2 junctophilin 2 1.77467
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.76746
IRF3 interferon regulatory factor 3 1.76615
ANXA9 annexin A9 1.75931
MAST4 microtubule associated serine/threonine kinase family member 4 1.75394
BPGM 2,3-bisphosphoglycerate mutase 1.75191
SNCG synuclein, gamma (breast cancer-specific protein 1) 1.74119
FABP4 fatty acid binding protein 4, adipocyte 1.73899
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 1.73693
MYH14 myosin, heavy chain 14, non-muscle 1.73526
SH2D4A SH2 domain containing 4A 1.73403
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.73254
GSTM2 glutathione S-transferase mu 2 (muscle) 1.72865
TMPRSS4 transmembrane protease, serine 4 1.72647
NFRKB nuclear factor related to kappaB binding protein 1.7262
PCDH1 protocadherin 1 1.72248
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.70623
CTSH cathepsin H 1.69884
NLRP2 NLR family, pyrin domain containing 2 1.69687
PSCA prostate stem cell antigen 1.69347
CAPN1 calpain 1, (mu/I) large subunit 1.69315
VGLL1 vestigial-like family member 1 1.6815
LPCAT4 lysophosphatidylcholine acyltransferase 4 1.6751
GLTSCR1 glioma tumor suppressor candidate region gene 1 1.67489
SPHK2 sphingosine kinase 2 1.67351
EVPL envoplakin 1.65627
ERGIC3 ERGIC and golgi 3 1.65239
AADAC arylacetamide deacetylase 1.64803
VIPR1 vasoactive intestinal peptide receptor 1 1.64508
CHKA choline kinase alpha 1.64396
PLXNA1 plexin A1 1.64156
SCCPDH saccharopine dehydrogenase (putative) 1.62196
CSNK1D casein kinase 1, delta 1.61254
RABGAP1L RAB GTPase activating protein 1-like 1.60883
TEAD3 TEA domain family member 3 1.6086
SH3TC2 SH3 domain and tetratricopeptide repeats 2 1.60777
OPRL1 opiate receptor-like 1 1.60739
ARHGAP35 Rho GTPase activating protein 35 1.6062
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 1.60261
PPL periplakin 1.59851
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.59744
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.5966
IRF1 interferon regulatory factor 1 1.59238
RHOBTB2 Rho-related BTB domain containing 2 1.59047
GP9 glycoprotein IX (platelet) 1.58877
LMBR1L limb development membrane protein 1-like 1.58822
ANGEL1 angel homolog 1 (Drosophila) 1.57819
GORASP1 golgi reassembly stacking protein 1, 65kDa 1.57309
TLR3 toll-like receptor 3 1.56898
ITPKC inositol-trisphosphate 3-kinase C 1.56795
BAIAP2 BAI1-associated protein 2 1.56732
ACOX3 acyl-CoA oxidase 3, pristanoyl 1.56295
ALOX5 arachidonate 5-lipoxygenase 1.56295
REEP4 receptor accessory protein 4 1.55856
TMEM51 transmembrane protein 51 1.55316
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1.55105
ZFP36L2 ZFP36 ring finger protein-like 2 1.55026
HOXA1 homeobox A1 1.54543
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 1.53856
LY6D lymphocyte antigen 6 complex, locus D 1.53799
TRAFD1 TRAF-type zinc finger domain containing 1 1.5342
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 1.53244
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.52612
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 1.52364
NDEL1 nudE neurodevelopment protein 1-like 1 1.52164
RGS12 regulator of G-protein signaling 12 1.51499
ACAA1 acetyl-CoA acyltransferase 1 1.51454
LAMA5 laminin, alpha 5 1.51367
NDRG2 NDRG family member 2 1.50547
TMEM40 transmembrane protein 40 1.50338
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.49918
SOX13 SRY (sex determining region Y)-box 13 1.49367
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.49197
PLXNB2 plexin B2 1.49028
NOSIP nitric oxide synthase interacting protein 1.48958
STRN4 striatin, calmodulin binding protein 4 1.4871
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.48464
KEL Kell blood group, metallo-endopeptidase 1.48178
ZNF587 zinc finger protein 587 1.47865
PURA purine-rich element binding protein A 1.46565
LYPD3 LY6/PLAUR domain containing 3 1.46025
KIF3B kinesin family member 3B 1.4599
MMRN2 multimerin 2 1.45618
ZNF331 zinc finger protein 331 1.45245
BHLHE41 basic helix-loop-helix family, member e41 1.44952
RECQL5 RecQ protein-like 5 1.44855
BAX BCL2-associated X protein 1.44803
AAK1 AP2 associated kinase 1 1.44798
PEPD peptidase D 1.44552
KRT7 keratin 7, type II 1.44176
CLPTM1 cleft lip and palate associated transmembrane protein 1 1.44009
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 1.43943
CLDN4 claudin 4 1.43767
CELP carboxyl ester lipase pseudogene 1.43679
ADGRF1 adhesion G protein-coupled receptor F1 1.43346
TEX11 testis expressed 11 1.43181
FAM106A family with sequence similarity 106, member A 1.43058
DEFA4 defensin, alpha 4, corticostatin 1.43056
IDUA iduronidase, alpha-L- 1.42858
STK24 serine/threonine kinase 24 1.42783
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 1.42431
BAZ2A bromodomain adjacent to zinc finger domain, 2A 1.42277
DUSP9 dual specificity phosphatase 9 1.42071
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.4193
MPZL2 myelin protein zero-like 2 1.41905

low expression

Symbol Name Standardized Value
DSTN destrin (actin depolymerizing factor) -3.53725
RBM5 RNA binding motif protein 5 -3.53725
IFRD2 interferon-related developmental regulator 2 -3.53725
RBM6 RNA binding motif protein 6 -3.53725
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -3.53725
TUSC2 tumor suppressor candidate 2 -3.53725
TMEM115 transmembrane protein 115 -3.53725
HYAL2 hyaluronoglucosaminidase 2 -3.53723
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -3.53699
CYB561D2 cytochrome b561 family, member D2 -3.50682
RABGAP1 RAB GTPase activating protein 1 -3.17091
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -3.13471
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -3.00208
IFT38 intraflagellar transport 38 -2.89288
FER fer (fps/fes related) tyrosine kinase -2.74589
RRBP1 ribosome binding protein 1 -2.63363
DOCK4 dedicator of cytokinesis 4 -2.62201
HEMK1 HemK methyltransferase family member 1 -2.60275
WFDC2 WAP four-disulfide core domain 2 -2.55433
HYI hydroxypyruvate isomerase (putative) -2.52214
KLHL9 kelch-like family member 9 -2.39604
SETD8 SET domain containing (lysine methyltransferase) 8 -2.36046
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -2.31808
CARD8 caspase recruitment domain family, member 8 -2.29621
HIST1H2AM histone cluster 1, H2am -2.29148
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.23396
ARFRP1 ADP-ribosylation factor related protein 1 -2.23101
KIAA0922 KIAA0922 -2.1909
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.16047
CBX5 chromobox homolog 5 -2.15786
WAPAL wings apart-like homolog (Drosophila) -2.14317
LDHA lactate dehydrogenase A -2.13421
COL18A1 collagen, type XVIII, alpha 1 -2.12881
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -2.11129
GSTA4 glutathione S-transferase alpha 4 -2.10151
DNA2 DNA replication helicase/nuclease 2 -2.06543
HPS5 Hermansky-Pudlak syndrome 5 -2.00207
FMOD fibromodulin -1.9622
SLC26A4 solute carrier family 26 (anion exchanger), member 4 -1.94916
SMNDC1 survival motor neuron domain containing 1 -1.9203
CORO1C coronin, actin binding protein, 1C -1.90972
PDHB pyruvate dehydrogenase (lipoamide) beta -1.90784
FOXF1 forkhead box F1 -1.90682
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -1.90066
FASTKD3 FAST kinase domains 3 -1.8834
CDH19 cadherin 19, type 2 -1.87646
PAX8 paired box 8 -1.83914
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -1.83539
ADAM5 ADAM metallopeptidase domain 5 (pseudogene) -1.80511
KLF13 Kruppel-like factor 13 -1.8025
TRIM10 tripartite motif containing 10 -1.80012
NTS neurotensin -1.78218
FHIT fragile histidine triad -1.76107
IGF1 insulin-like growth factor 1 (somatomedin C) -1.76062
CD3D CD3d molecule, delta (CD3-TCR complex) -1.75711
LOX lysyl oxidase -1.75513
BNC2 basonuclin 2 -1.73926
PIAS2 protein inhibitor of activated STAT, 2 -1.72849
ABHD14A abhydrolase domain containing 14A -1.72584
MMP3 matrix metallopeptidase 3 -1.72352
G0S2 G0/G1 switch 2 -1.71297
RAD54B RAD54 homolog B (S. cerevisiae) -1.70634
EDNRA endothelin receptor type A -1.70514
GPATCH4 G patch domain containing 4 -1.69136
SIRT1 sirtuin 1 -1.69131
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -1.69099
CARF calcium responsive transcription factor -1.6786
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.67503
SULF1 sulfatase 1 -1.6745
WDR12 WD repeat domain 12 -1.67189
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -1.66081
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 -1.64575
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -1.64363
PARP6 poly (ADP-ribose) polymerase family, member 6 -1.64334
ITGA7 integrin, alpha 7 -1.63422
COPS4 COP9 signalosome subunit 4 -1.63322
HPN hepsin -1.63034
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -1.62203
ASTN1 astrotactin 1 -1.62029
AHSG alpha-2-HS-glycoprotein -1.60662
BMP8B bone morphogenetic protein 8b -1.59419
OSTF1 osteoclast stimulating factor 1 -1.59176
TLN2 talin 2 -1.57973
RAB28 RAB28, member RAS oncogene family -1.57903
CERK ceramide kinase -1.57303
DCN decorin -1.5677
YEATS2 YEATS domain containing 2 -1.56522
CNTNAP3B contactin associated protein-like 3B -1.55528
ALB albumin -1.55339
LY96 lymphocyte antigen 96 -1.55167
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -1.54155
SMC3 structural maintenance of chromosomes 3 -1.54074
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -1.53888
SDC2 syndecan 2 -1.5378
ADGRE1 adhesion G protein-coupled receptor E1 -1.52994
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -1.52833
ZNF214 zinc finger protein 214 -1.52815
MALT1 MALT1 paracaspase -1.52607
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.52238
NR2C2 nuclear receptor subfamily 2, group C, member 2 -1.51791
KLF1 Kruppel-like factor 1 (erythroid) -1.51375
CAPRIN1 cell cycle associated protein 1 -1.50788
NOL10 nucleolar protein 10 -1.49432
EXOSC9 exosome component 9 -1.49286
SIX2 SIX homeobox 2 -1.48692
MYO7A myosin VIIA -1.48528
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -1.48013
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -1.47776
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -1.46625
AMD1 adenosylmethionine decarboxylase 1 -1.4565
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -1.4513
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -1.44625
NPY4R neuropeptide Y receptor Y4 -1.43542
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -1.43012
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 -1.42902
PDCD11 programmed cell death 11 -1.41985
DUSP12 dual specificity phosphatase 12 -1.41922