SW837 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

260 genes with high or low expression in SW837 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 3.60177
HAUS7 HAUS augmin-like complex, subunit 7 3.54307
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 3.4969
F8A1 coagulation factor VIII-associated 1 3.32986
SMAD6 SMAD family member 6 3.195
BCAP31 B-cell receptor-associated protein 31 3.13169
MECP2 methyl CpG binding protein 2 3.1078
PLXNA3 plexin A3 3.09356
SLC10A3 solute carrier family 10, member 3 3.07714
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.0246
TAZ tafazzin 2.94013
DNASE1L1 deoxyribonuclease I-like 1 2.89351
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 2.87681
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 2.8651
IRAK1 interleukin-1 receptor-associated kinase 1 2.76724
ABLIM1 actin binding LIM protein 1 2.75304
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.72113
FAM50A family with sequence similarity 50, member A 2.70516
EMD emerin 2.66967
FAM3A family with sequence similarity 3, member A 2.66569
CETN2 centrin, EF-hand protein, 2 2.58415
BAIAP3 BAI1-associated protein 3 2.58401
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 2.58302
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.58176
UBL4A ubiquitin-like 4A 2.57009
SBSPON somatomedin B and thrombospondin, type 1 domain containing 2.38694
F8 coagulation factor VIII, procoagulant component 2.35736
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.28202
DKC1 dyskeratosis congenita 1, dyskerin 2.27942
VBP1 von Hippel-Lindau binding protein 1 2.27353
HMGB3 high mobility group box 3 2.26333
SGPL1 sphingosine-1-phosphate lyase 1 2.26161
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.20552
TREH trehalase (brush-border membrane glycoprotein) 2.19174
KLK10 kallikrein-related peptidase 10 2.17769
RHOBTB3 Rho-related BTB domain containing 3 2.17321
FAF2 Fas associated factor family member 2 2.15916
TMCO6 transmembrane and coiled-coil domains 6 2.14524
PHLDB1 pleckstrin homology-like domain, family B, member 1 2.14499
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.12378
GDI1 GDP dissociation inhibitor 1 2.11749
ALPPL2 alkaline phosphatase, placental-like 2 2.1022
IDS iduronate 2-sulfatase 2.08408
TTC12 tetratricopeptide repeat domain 12 2.03457
CLDN9 claudin 9 2.01736
DDHD2 DDHD domain containing 2 1.96531
OGFR opioid growth factor receptor 1.96261
TNS4 tensin 4 1.95057
GALE UDP-galactose-4-epimerase 1.9505
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 1.91906
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 1.87836
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.87735
SPINK5 serine peptidase inhibitor, Kazal type 5 1.85058
DLG5 discs, large homolog 5 (Drosophila) 1.84385
PARP12 poly (ADP-ribose) polymerase family, member 12 1.84154
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 1.82619
JRKL JRK-like 1.81823
TUG1 taurine up-regulated 1 (non-protein coding) 1.81037
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.79803
ZNF185 zinc finger protein 185 (LIM domain) 1.77852
HIRA histone cell cycle regulator 1.76536
MMP7 matrix metallopeptidase 7 1.76281
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.75773
HOXB5 homeobox B5 1.74488
PHACTR2 phosphatase and actin regulator 2 1.73394
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 1.71671
IL22RA1 interleukin 22 receptor, alpha 1 1.70921
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.70901
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 1.70835
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.70692
FLNA filamin A, alpha 1.69714
SMPX small muscle protein, X-linked 1.6822
PWWP2A PWWP domain containing 2A 1.67735
HMBS hydroxymethylbilane synthase 1.66608
IRS1 insulin receptor substrate 1 1.66276
WNT11 wingless-type MMTV integration site family, member 11 1.65932
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.65655
SAP30L SAP30-like 1.65652
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 1.65527
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 1.647
IFI35 interferon-induced protein 35 1.64478
EFNA2 ephrin-A2 1.63305
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1.62213
APOL5 apolipoprotein L, 5 1.61859
COL9A3 collagen, type IX, alpha 3 1.61856
FURIN furin (paired basic amino acid cleaving enzyme) 1.61399
SSR4 signal sequence receptor, delta 1.61228
LZTR1 leucine-zipper-like transcription regulator 1 1.60704
PACS2 phosphofurin acidic cluster sorting protein 2 1.60437
ERO1L ERO1-like (S. cerevisiae) 1.60115
TRIM14 tripartite motif containing 14 1.59603
PLA2G16 phospholipase A2, group XVI 1.59431
LOC390998 ribosomal protein L10 pseudogene 1.58428
SAV1 salvador family WW domain containing protein 1 1.58315
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.57731
UPK2 uroplakin 2 1.57669
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 1.5737
EDAR ectodysplasin A receptor 1.57112
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.56878
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.56824
STX3 syntaxin 3 1.56759
ACAD10 acyl-CoA dehydrogenase family, member 10 1.56298
PNKP polynucleotide kinase 3'-phosphatase 1.55473
LSM1 LSM1, U6 small nuclear RNA associated 1.55154
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase 1.5455
MUC8 mucin 8 1.53874
KIF20B kinesin family member 20B 1.53813
ALS2CL ALS2 C-terminal like 1.53802
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 1.53449
MMD monocyte to macrophage differentiation-associated 1.52935
MX1 MX dynamin-like GTPase 1 1.52858
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 1.52774
GSDMB gasdermin B 1.52635
KLK11 kallikrein-related peptidase 11 1.52025
SACK1E scaffolding CK1 anchoring protein E 1.51568
HDAC3 histone deacetylase 3 1.51056
CALML4 calmodulin-like 4 1.5102
HIST1H2AE histone cluster 1, H2ae 1.50921
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 1.50913
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.50696
GNB5 guanine nucleotide binding protein (G protein), beta 5 1.50126
POU2F3 POU class 2 homeobox 3 1.49662
HAP1 huntingtin-associated protein 1 1.49025
ATP10B ATPase, class V, type 10B 1.4879
HMMR hyaluronan-mediated motility receptor (RHAMM) 1.48262
MGLL monoglyceride lipase 1.48162
PKP4 plakophilin 4 1.48143
ENDOD1 endonuclease domain containing 1 1.47079
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.46659
KLK6 kallikrein-related peptidase 6 1.45996
TRIM21 tripartite motif containing 21 1.45754
RNF186 ring finger protein 186 1.45566
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.45366
FUCA1 fucosidase, alpha-L- 1, tissue 1.45321
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.45225
TMPRSS5 transmembrane protease, serine 5 1.44999
LMO4 LIM domain only 4 1.44671
KRT23 keratin 23, type I 1.44408
MX2 MX dynamin-like GTPase 2 1.44306
MUC13 mucin 13, cell surface associated 1.44109
CDC23 cell division cycle 23 1.43774
SERINC5 serine incorporator 5 1.43579
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.43532
SECTM1 secreted and transmembrane 1 1.43506
TEP1 telomerase-associated protein 1 1.43355
MUC3B mucin 3B, cell surface associated 1.42193
DCPS decapping enzyme, scavenger 1.42173

low expression

Symbol Name Standardized Value
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -3.53725
VAMP7 vesicle-associated membrane protein 7 -3.52863
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) -3.04972
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.70017
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) -2.614
RIC8A RIC8 guanine nucleotide exchange factor A -2.60116
GTF3A general transcription factor IIIA -2.59314
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -2.41081
SARS seryl-tRNA synthetase -2.32876
ZNF264 zinc finger protein 264 -2.32221
LRRN2 leucine rich repeat neuronal 2 -2.29316
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -2.2837
CDH19 cadherin 19, type 2 -2.25627
OSTM1 osteopetrosis associated transmembrane protein 1 -2.20999
PLEK pleckstrin -2.16297
GCAT glycine C-acetyltransferase -2.13578
RPS28 ribosomal protein S28 -2.11265
MRPL34 mitochondrial ribosomal protein L34 -2.09258
NR0B1 nuclear receptor subfamily 0, group B, member 1 -2.04569
ELOVL5 ELOVL fatty acid elongase 5 -2.03311
AZI2 5-azacytidine induced 2 -2.0074
PLCL2 phospholipase C-like 2 -2.00291
ATG4A autophagy related 4A, cysteine peptidase -1.99446
ZNF331 zinc finger protein 331 -1.99249
GLO1 glyoxalase I -1.98799
ZC3H13 zinc finger CCCH-type containing 13 -1.96582
DOPEY1 dopey family member 1 -1.95345
CLEC4E C-type lectin domain family 4, member E -1.92511
OPHN1 oligophrenin 1 -1.9209
FRMD1 FERM domain containing 1 -1.89898
CALML3 calmodulin-like 3 -1.89799
RABGGTB Rab geranylgeranyltransferase, beta subunit -1.89172
ATF4 activating transcription factor 4 -1.88349
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.8828
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -1.86195
TSC1 tuberous sclerosis 1 -1.8614
OGFRL1 opioid growth factor receptor-like 1 -1.84329
COL8A2 collagen, type VIII, alpha 2 -1.82152
EXOC6B exocyst complex component 6B -1.82
ZNF551 zinc finger protein 551 -1.81543
PRKACB protein kinase, cAMP-dependent, catalytic, beta -1.81303
SH3GL3 SH3-domain GRB2-like 3 -1.80836
PHOX2A paired-like homeobox 2a -1.79226
USP24 ubiquitin specific peptidase 24 -1.78966
IL11 interleukin 11 -1.78536
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.7717
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -1.76355
MAGEH1 melanoma antigen family H1 -1.74893
GPSM3 G-protein signaling modulator 3 -1.74332
RPH3A rabphilin 3A -1.73686
RNMT RNA (guanine-7-) methyltransferase -1.73125
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -1.68691
BICD1 bicaudal D homolog 1 (Drosophila) -1.68494
MPDZ multiple PDZ domain protein -1.6779
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) -1.67025
NUP210 nucleoporin 210kDa -1.66967
VLDLR very low density lipoprotein receptor -1.65933
EPS15 epidermal growth factor receptor pathway substrate 15 -1.65442
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.64643
GARS glycyl-tRNA synthetase -1.63446
SNX3 sorting nexin 3 -1.61323
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -1.61176
RGS19 regulator of G-protein signaling 19 -1.60305
GLMN glomulin, FKBP associated protein -1.59814
WDR46 WD repeat domain 46 -1.59618
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -1.59519
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -1.58848
OXSR1 oxidative stress responsive 1 -1.5805
DCP1A decapping mRNA 1A -1.57664
ZNF507 zinc finger protein 507 -1.57322
MDFIC MyoD family inhibitor domain containing -1.5608
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -1.55932
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.55713
ZNF24 zinc finger protein 24 -1.54915
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -1.54607
LPPR2 lipid phosphate phosphatase-related protein type 2 -1.5391
MRPS18C mitochondrial ribosomal protein S18C -1.53724
BICC1 BicC family RNA binding protein 1 -1.53665
FCAR Fc fragment of IgA receptor -1.53562
SETMAR SET domain and mariner transposase fusion gene -1.52928
ASF1A anti-silencing function 1A histone chaperone -1.52593
RTCA RNA 3'-terminal phosphate cyclase -1.52342
STK19 serine/threonine kinase 19 -1.51291
FHIT fragile histidine triad -1.50945
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.50669
CPN2 carboxypeptidase N, polypeptide 2 -1.50227
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -1.49907
MOS v-mos Moloney murine sarcoma viral oncogene homolog -1.49843
CISH cytokine inducible SH2-containing protein -1.4978
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -1.48418
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -1.48219
C3AR1 complement component 3a receptor 1 -1.47866
THOC5 THO complex 5 -1.47661
DDIT3 DNA-damage-inducible transcript 3 -1.46537
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -1.46185
CD34 CD34 molecule -1.45943
ATG10 autophagy related 10 -1.45589
EDNRA endothelin receptor type A -1.45483
FOXE1 forkhead box E1 -1.45239
BCL2 B-cell CLL/lymphoma 2 -1.4515
MKKS McKusick-Kaufman syndrome -1.44962
ZNF304 zinc finger protein 304 -1.4446
INHBE inhibin, beta E -1.44454
CEP63 centrosomal protein 63kDa -1.44327
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 -1.44293
MIS12 MIS12 kinetochore complex component -1.44071
OLFML3 olfactomedin-like 3 -1.43536
RNGTT RNA guanylyltransferase and 5'-phosphatase -1.43424
TRIB3 tribbles pseudokinase 3 -1.43386
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -1.43328
RECK reversion-inducing-cysteine-rich protein with kazal motifs -1.42533
DRG2 developmentally regulated GTP binding protein 2 -1.42172
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -1.41796