SW900 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

216 genes with high or low expression in SW900 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
RASL10A RAS-like, family 10, member A 3.59291
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.89209
UBE2K ubiquitin-conjugating enzyme E2K 2.74323
TMEM156 transmembrane protein 156 2.61345
OASL 2'-5'-oligoadenylate synthetase-like 2.57982
CHMP6 charged multivesicular body protein 6 2.567
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.45276
HIGD2A HIG1 hypoxia inducible domain family, member 2A 2.43724
WDR1 WD repeat domain 1 2.39117
ZC3HAV1 zinc finger CCCH-type, antiviral 1 2.29777
GPRC5C G protein-coupled receptor, class C, group 5, member C 2.13495
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 2.12708
FOSL2 FOS-like antigen 2 2.11701
ABR active BCR-related 2.11459
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.07568
WFS1 Wolfram syndrome 1 (wolframin) 2.06509
COPS8 COP9 signalosome subunit 8 2.05695
NHP2 NHP2 ribonucleoprotein 2.03813
ACADVL acyl-CoA dehydrogenase, very long chain 2.01686
RUFY1 RUN and FYVE domain containing 1 1.96042
RPH3AL rabphilin 3A-like (without C2 domains) 1.9328
KRT75 keratin 75, type II 1.92689
IDS iduronate 2-sulfatase 1.91284
PLEKHA5 pleckstrin homology domain containing, family A member 5 1.90118
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.87644
GABARAP GABA(A) receptor-associated protein 1.86107
MYO1C myosin IC 1.83382
ADGRF5 adhesion G protein-coupled receptor F5 1.82692
ADAR adenosine deaminase, RNA-specific 1.82436
PRPF8 pre-mRNA processing factor 8 1.81175
LMAN2 lectin, mannose-binding 2 1.80431
CCDC92 coiled-coil domain containing 92 1.80032
FAF2 Fas associated factor family member 2 1.7972
TBC1D22A TBC1 domain family, member 22A 1.79661
SQSTM1 sequestosome 1 1.77543
LSP1 lymphocyte-specific protein 1 1.75958
SCARF1 scavenger receptor class F, member 1 1.75794
SGSM2 small G protein signaling modulator 2 1.74913
GEMIN7 gem (nuclear organelle) associated protein 7 1.74813
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.73122
BRD1 bromodomain containing 1 1.72748
ETNK1 ethanolamine kinase 1 1.70519
SPDL1 spindle apparatus coiled-coil protein 1 1.69894
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.69173
GAS2L1 growth arrest-specific 2 like 1 1.69091
ACTN4 actinin, alpha 4 1.66247
CANX calnexin 1.65522
KLRC3 killer cell lectin-like receptor subfamily C, member 3 1.65041
TRAPPC12 trafficking protein particle complex 12 1.64669
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.64467
FAM89B family with sequence similarity 89, member B 1.644
ARHGAP35 Rho GTPase activating protein 35 1.64177
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.64124
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.6359
CLASP1 cytoplasmic linker associated protein 1 1.61005
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 1.60372
F13A1 coagulation factor XIII, A1 polypeptide 1.60156
TCN2 transcobalamin II 1.59621
TMEM11 transmembrane protein 11 1.5937
TMEM109 transmembrane protein 109 1.59074
AKAP10 A kinase (PRKA) anchor protein 10 1.57715
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.57512
DVL2 dishevelled segment polarity protein 2 1.56706
ETV1 ets variant 1 1.56699
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.5567
TOR1AIP2 torsin A interacting protein 2 1.5558
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.55276
SLC4A2 solute carrier family 4 (anion exchanger), member 2 1.54524
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 1.54467
SAP130 Sin3A-associated protein, 130kDa 1.54295
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.53753
PSAP prosaposin 1.53474
CLDN10 claudin 10 1.52819
PNKP polynucleotide kinase 3'-phosphatase 1.51955
NF2 neurofibromin 2 (merlin) 1.51067
FOXM1 forkhead box M1 1.51043
GUK1 guanylate kinase 1 1.50873
ASPH aspartate beta-hydroxylase 1.50624
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 1.49397
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 1.49214
BAG3 BCL2-associated athanogene 3 1.49138
TRIO trio Rho guanine nucleotide exchange factor 1.47856
USP22 ubiquitin specific peptidase 22 1.4731
PCDH7 protocadherin 7 1.46954
SCN1B sodium channel, voltage gated, type I beta subunit 1.46679
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 1.46205
GTSE1 G-2 and S-phase expressed 1 1.45912
TMED9 transmembrane emp24 protein transport domain containing 9 1.45626
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 1.45445
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 1.45429
CIT citron rho-interacting serine/threonine kinase 1.4516
FSTL4 follistatin-like 4 1.45059
RPA1 replication protein A1, 70kDa 1.44425
COMMD4 COMM domain containing 4 1.44256
RANBP17 RAN binding protein 17 1.44244
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.44002
CAPN2 calpain 2, (m/II) large subunit 1.43823
AHR aryl hydrocarbon receptor 1.43641
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.4364
PF4 platelet factor 4 1.43366
WBP11 WW domain binding protein 11 1.43324
TMEM127 transmembrane protein 127 1.42553
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 1.42418
CLTB clathrin, light chain B 1.41879

low expression

Symbol Name Standardized Value
MOSPD2 motile sperm domain containing 2 -3.53723
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -2.88797
ZNF24 zinc finger protein 24 -2.77732
ZBTB6 zinc finger and BTB domain containing 6 -2.71215
NF1 neurofibromin 1 -2.63111
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.55021
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -2.45901
ELP4 elongator acetyltransferase complex subunit 4 -2.45106
NBR2 neighbor of BRCA1 gene 2 (non-protein coding) -2.40612
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.34494
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -2.34033
MFN1 mitofusin 1 -2.29558
RNF13 ring finger protein 13 -2.27121
NUP160 nucleoporin 160kDa -2.24773
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.24456
HDAC3 histone deacetylase 3 -2.24015
CLDN15 claudin 15 -2.17396
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.15459
GLUD1 glutamate dehydrogenase 1 -2.07803
FBXO3 F-box protein 3 -2.01742
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -2.00278
GIPC2 GIPC PDZ domain containing family, member 2 -1.99773
ATG13 autophagy related 13 -1.99518
DPH2 DPH2 homolog (S. cerevisiae) -1.97929
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -1.97499
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -1.97213
PEX12 peroxisomal biogenesis factor 12 -1.9603
SORD sorbitol dehydrogenase -1.95299
EIF3M eukaryotic translation initiation factor 3, subunit M -1.92119
PTDSS2 phosphatidylserine synthase 2 -1.91979
CAPRIN1 cell cycle associated protein 1 -1.91271
NUP98 nucleoporin 98kDa -1.8908
IFNA16 interferon, alpha 16 -1.88668
APIP APAF1 interacting protein -1.86467
SIAH2 siah E3 ubiquitin protein ligase 2 -1.84119
CRELD1 cysteine-rich with EGF-like domains 1 -1.83959
WAPAL wings apart-like homolog (Drosophila) -1.83704
SNIP1 Smad nuclear interacting protein 1 -1.81675
RAB9A RAB9A, member RAS oncogene family -1.80368
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 -1.79904
AVIL advillin -1.79695
ZCCHC10 zinc finger, CCHC domain containing 10 -1.78894
MTAP methylthioadenosine phosphorylase -1.78176
TSEN2 TSEN2 tRNA splicing endonuclease subunit -1.77564
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -1.77494
FAN1 FANCD2/FANCI-associated nuclease 1 -1.77157
AR androgen receptor -1.7703
LIG4 ligase IV, DNA, ATP-dependent -1.74174
PRMT3 protein arginine methyltransferase 3 -1.7391
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.72732
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -1.70336
IKZF5 IKAROS family zinc finger 5 (Pegasus) -1.7008
MGC12488 -1.69897
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -1.69762
IPO7 importin 7 -1.68969
HIST1H2AG histone cluster 1, H2ag -1.66824
API5 apoptosis inhibitor 5 -1.66296
DLG1 discs, large homolog 1 (Drosophila) -1.66186
CLCA1 chloride channel accessory 1 -1.65964
RAD23B RAD23 homolog B (S. cerevisiae) -1.65714
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 -1.65253
TSG101 tumor susceptibility 101 -1.64265
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -1.64183
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 -1.63663
RLBP1 retinaldehyde binding protein 1 -1.62829
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene -1.61321
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -1.61048
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -1.60351
NCBP2 nuclear cap binding protein subunit 2, 20kDa -1.59648
IQCK IQ motif containing K -1.58894
EIF3F eukaryotic translation initiation factor 3, subunit F -1.58748
EXT2 exostosin glycosyltransferase 2 -1.58591
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -1.58265
SMAD2 SMAD family member 2 -1.57027
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -1.5682
NMD3 NMD3 ribosome export adaptor -1.5665
IRF8 interferon regulatory factor 8 -1.56243
RPL17 ribosomal protein L17 -1.55684
GOLGA8B golgin A8 family, member B -1.5542
TJP3 tight junction protein 3 -1.55305
BRD7 bromodomain containing 7 -1.548
FXYD3 FXYD domain containing ion transport regulator 3 -1.54704
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -1.54366
MRPS15 mitochondrial ribosomal protein S15 -1.54254
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -1.5386
GLRA3 glycine receptor, alpha 3 -1.53452
MTCH2 mitochondrial carrier 2 -1.53298
TNNI3 troponin I type 3 (cardiac) -1.53109
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -1.52124
KCTD20 potassium channel tetramerization domain containing 20 -1.52085
KAT8 K(lysine) acetyltransferase 8 -1.51113
MED7 mediator complex subunit 7 -1.49803
RRAGB Ras-related GTP binding B -1.49795
CD3E CD3e molecule, epsilon (CD3-TCR complex) -1.49272
NAT10 N-acetyltransferase 10 (GCN5-related) -1.48899
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -1.48626
YAF2 YY1 associated factor 2 -1.47794
PLAC1 placenta-specific 1 -1.47704
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -1.46966
TMEM41B transmembrane protein 41B -1.46108
EIF4A2 eukaryotic translation initiation factor 4A2 -1.46026
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) -1.45034
MEX3C mex-3 RNA binding family member C -1.44706
SENP6 SUMO1/sentrin specific peptidase 6 -1.44328
PCSK6 proprotein convertase subtilisin/kexin type 6 -1.44082
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -1.43864
ADRBK1 adrenergic, beta, receptor kinase 1 -1.43344
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -1.43239
DDO D-aspartate oxidase -1.43132
ZBTB11 zinc finger and BTB domain containing 11 -1.42909
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -1.41966
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -1.41591