SW954 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: squamous cell carcinoma (Cell Line Ontology, CLO_0009204)
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Genes

305 genes with high or low expression in SW954 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
FMO4 flavin containing monooxygenase 4 3.56073
WISP3 WNT1 inducible signaling pathway protein 3 3.0597
CLCA4 chloride channel accessory 4 2.85445
SCPEP1 serine carboxypeptidase 1 2.78379
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.70114
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.56445
METAP1 methionyl aminopeptidase 1 2.52062
MSMB microseminoprotein, beta- 2.47991
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.41883
CLCA2 chloride channel accessory 2 2.39144
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 2.37791
GSTP1 glutathione S-transferase pi 1 2.3131
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.29401
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.22713
TMEM134 transmembrane protein 134 2.2084
NCK1 NCK adaptor protein 1 2.19466
INPP1 inositol polyphosphate-1-phosphatase 2.13384
IDO1 indoleamine 2,3-dioxygenase 1 2.12498
KDM2A lysine (K)-specific demethylase 2A 2.10125
TLR3 toll-like receptor 3 2.07742
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 2.03344
MPPED2 metallophosphoesterase domain containing 2 1.99521
ERAP1 endoplasmic reticulum aminopeptidase 1 1.99335
DUOX2 dual oxidase 2 1.98847
FGF1 fibroblast growth factor 1 (acidic) 1.93313
BTN3A3 butyrophilin, subfamily 3, member A3 1.90823
KLK13 kallikrein-related peptidase 13 1.89767
ARSF arylsulfatase F 1.88855
LGALS7 lectin, galactoside-binding, soluble, 7 1.88851
GPR87 G protein-coupled receptor 87 1.87269
CROT carnitine O-octanoyltransferase 1.83822
PRKCI protein kinase C, iota 1.83201
AIP aryl hydrocarbon receptor interacting protein 1.8259
FAM69A family with sequence similarity 69, member A 1.81968
FZD10 frizzled class receptor 10 1.81834
IQCK IQ motif containing K 1.81593
CNGA1 cyclic nucleotide gated channel alpha 1 1.80484
IL33R interleukin 33 receptor 1.8033
KRT15 keratin 15, type I 1.76317
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.75387
MMP12 matrix metallopeptidase 12 1.74204
ASCC3 activating signal cointegrator 1 complex subunit 3 1.74131
LY6D lymphocyte antigen 6 complex, locus D 1.73073
MMP13 matrix metallopeptidase 13 1.72055
EGFL6 EGF-like-domain, multiple 6 1.71886
OLFM4 olfactomedin 4 1.71809
MORC3 MORC family CW-type zinc finger 3 1.71795
CLDN1 claudin 1 1.71263
RHCG Rh family, C glycoprotein 1.71053
KRT4 keratin 4, type II 1.70539
PTAFR platelet-activating factor receptor 1.69591
RTP4 receptor (chemosensory) transporter protein 4 1.69443
MR1 major histocompatibility complex, class I-related 1.67869
SRD5A3 steroid 5 alpha-reductase 3 1.67614
PADI3 peptidyl arginine deiminase, type III 1.67543
CXCL6 chemokine (C-X-C motif) ligand 6 1.67537
ACE2 angiotensin I converting enzyme 2 1.67216
SLC39A2 solute carrier family 39 (zinc transporter), member 2 1.66719
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.66136
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 1.66067
MYO1B myosin IB 1.64607
LGALS8 lectin, galactoside-binding, soluble, 8 1.64523
TLR5 toll-like receptor 5 1.6402
KIAA0513 KIAA0513 1.63073
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.62452
DLK2 delta-like 2 homolog (Drosophila) 1.62383
STARD5 StAR-related lipid transfer (START) domain containing 5 1.62246
DDB2 damage-specific DNA binding protein 2, 48kDa 1.6133
DAAM1 dishevelled associated activator of morphogenesis 1 1.6125
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 1.61153
UBA6 ubiquitin-like modifier activating enzyme 6 1.60843
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 1.60398
UBE2D1 ubiquitin-conjugating enzyme E2D 1 1.59569
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.59207
DEFB1 defensin, beta 1 1.59198
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 1.59122
SAMD9 sterile alpha motif domain containing 9 1.58666
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.58344
MARK2 MAP/microtubule affinity-regulating kinase 2 1.5833
RAD9A RAD9 homolog A (S. pombe) 1.57108
DST dystonin 1.57095
SSH3 slingshot protein phosphatase 3 1.56406
OAT ornithine aminotransferase 1.55495
MMP10 matrix metallopeptidase 10 1.53708
TRAFD1 TRAF-type zinc finger domain containing 1 1.53433
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 1.52954
ZC3H12A zinc finger CCCH-type containing 12A 1.52341
DUOX1 dual oxidase 1 1.52261
CREB1 cAMP responsive element binding protein 1 1.51326
FAT2 FAT atypical cadherin 2 1.50902
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 1.50721
ANXA2P3 annexin A2 pseudogene 3 1.50689
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.50662
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.50434
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.50096
TREH trehalase (brush-border membrane glycoprotein) 1.49881
CLDN8 claudin 8 1.49542
DHRS9 dehydrogenase/reductase (SDR family) member 9 1.48026
KRT13 keratin 13, type I 1.46297
TNNI2 troponin I type 2 (skeletal, fast) 1.45919
RNF141 ring finger protein 141 1.45535
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 1.45465
HCAR3 hydroxycarboxylic acid receptor 3 1.45456
IVL involucrin 1.44911
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.44623
FADD Fas (TNFRSF6)-associated via death domain 1.44351
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.44242
TLR1 toll-like receptor 1 1.44125
TMPRSS11D transmembrane protease, serine 11D 1.43785
FAIM Fas apoptotic inhibitory molecule 1.43599
CP ceruloplasmin (ferroxidase) 1.42974

low expression

Symbol Name Standardized Value
PTDSS2 phosphatidylserine synthase 2 -3.1387
TM7SF2 transmembrane 7 superfamily member 2 -3.10901
SHPK sedoheptulokinase -2.94998
CDH22 cadherin 22, type 2 -2.9239
INPPL1 inositol polyphosphate phosphatase-like 1 -2.68098
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) -2.63387
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 -2.6198
HYOU1 hypoxia up-regulated 1 -2.59777
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -2.58405
RNMT RNA (guanine-7-) methyltransferase -2.52288
ZPR1 ZPR1 zinc finger -2.50957
FKBP2 FK506 binding protein 2, 13kDa -2.49706
DGKD diacylglycerol kinase, delta 130kDa -2.48754
CHKA choline kinase alpha -2.46766
DENND4B DENN/MADD domain containing 4B -2.45826
IRF2BP1 interferon regulatory factor 2 binding protein 1 -2.45019
PCSK7 proprotein convertase subtilisin/kexin type 7 -2.39818
MRAS muscle RAS oncogene homolog -2.35668
EPN1 epsin 1 -2.34569
TSPYL2 TSPY-like 2 -2.32161
RUNDC3A RUN domain containing 3A -2.28303
TAZ tafazzin -2.27249
HMBS hydroxymethylbilane synthase -2.24929
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain -2.24889
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.23612
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -2.23459
TUSC2 tumor suppressor candidate 2 -2.22545
NXF1 nuclear RNA export factor 1 -2.20135
FICD FIC domain containing -2.19307
LEFTY2 left-right determination factor 2 -2.18275
TWF2 twinfilin actin binding protein 2 -2.10825
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.10596
MAST2 microtubule associated serine/threonine kinase 2 -2.1001
LPIN2 lipin 2 -2.08435
TESK1 testis-specific kinase 1 -2.08322
B3GAT3 beta-1,3-glucuronyltransferase 3 -2.07217
KIAA1654 KIAA1654 protein -2.0612
CD96 CD96 molecule -2.06086
ARL2 ADP-ribosylation factor-like 2 -2.05527
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.05325
MRPL2 mitochondrial ribosomal protein L2 -2.02667
GAB2 GRB2-associated binding protein 2 -2.02524
RBM6 RNA binding motif protein 6 -2.01657
ACAA2 acetyl-CoA acyltransferase 2 -2.01019
VASH2 vasohibin 2 -1.99648
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -1.99454
GANAB glucosidase, alpha; neutral AB -1.98914
LOC157562 uncharacterized LOC157562 -1.98205
RSAD1 radical S-adenosyl methionine domain containing 1 -1.98133
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 -1.97982
USP19 ubiquitin specific peptidase 19 -1.96655
IP6K1 inositol hexakisphosphate kinase 1 -1.96312
ASIP agouti signaling protein -1.96098
UBE2O ubiquitin-conjugating enzyme E2O -1.94631
AAAS achalasia, adrenocortical insufficiency, alacrimia -1.94526
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 -1.94277
AXIN1 axin 1 -1.94
SMAD4 SMAD family member 4 -1.92717
RAG1 recombination activating gene 1 -1.92458
RBM15B RNA binding motif protein 15B -1.91823
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -1.90565
CPLX2 complexin 2 -1.88797
MTMR8 myotubularin related protein 8 -1.88503
RAD54L2 RAD54-like 2 (S. cerevisiae) -1.88344
COL11A2 collagen, type XI, alpha 2 -1.88025
DPF2 D4, zinc and double PHD fingers family 2 -1.88005
RARA retinoic acid receptor, alpha -1.8796
SERGEF secretion regulating guanine nucleotide exchange factor -1.87485
NPY5R neuropeptide Y receptor Y5 -1.8713
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -1.86483
MEN1 multiple endocrine neoplasia I -1.86344
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.85772
PTGDR2 prostaglandin D2 receptor 2 -1.85104
SEH1L SEH1-like (S. cerevisiae) -1.83813
MBD1 methyl-CpG binding domain protein 1 -1.82668
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 -1.81964
GJC2 gap junction protein, gamma 2, 47kDa -1.81179
MEX3C mex-3 RNA binding family member C -1.81085
SLA Src-like-adaptor -1.80811
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -1.80313
MEF2D myocyte enhancer factor 2D -1.79937
SOX12 SRY (sex determining region Y)-box 12 -1.79834
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -1.79613
MKRN2 makorin ring finger protein 2 -1.79561
EFNA3 ephrin-A3 -1.79561
MBD2 methyl-CpG binding domain protein 2 -1.79561
SF1 splicing factor 1 -1.78958
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 -1.7885
MRPL49 mitochondrial ribosomal protein L49 -1.78726
KMT2D lysine (K)-specific methyltransferase 2D -1.78418
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -1.76958
DHODH dihydroorotate dehydrogenase (quinone) -1.76865
SRPR signal recognition particle receptor (docking protein) -1.76306
NCKIPSD NCK interacting protein with SH3 domain -1.75678
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -1.75481
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.75279
HNF4A hepatocyte nuclear factor 4, alpha -1.75113
USP36 ubiquitin specific peptidase 36 -1.7505
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -1.74796
DXO decapping exoribonuclease -1.74523
C2CD2L C2CD2-like -1.74122
DPYSL2 dihydropyrimidinase-like 2 -1.7269
E2F4 E2F transcription factor 4, p107/p130-binding -1.72447
AMPH amphiphysin -1.71824
GYPC glycophorin C (Gerbich blood group) -1.71581
INTS5 integrator complex subunit 5 -1.71441
CSH2 chorionic somatomammotropin hormone 2 -1.71333
NECAB3 N-terminal EF-hand calcium binding protein 3 -1.71085
TEX11 testis expressed 11 -1.706
ADAM3A ADAM metallopeptidase domain 3A (pseudogene) -1.69551
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin -1.67398
HDC histidine decarboxylase -1.667
MAN1C1 mannosidase, alpha, class 1C, member 1 -1.66629
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -1.66287
IQCC IQ motif containing C -1.65654
ZBTB5 zinc finger and BTB domain containing 5 -1.65641
OPRL1 opiate receptor-like 1 -1.65452
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -1.64604
OXSR1 oxidative stress responsive 1 -1.64452
NLK nemo-like kinase -1.62972
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 -1.62666
SGCE sarcoglycan, epsilon -1.625
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -1.62403
NGLY1 N-glycanase 1 -1.62252
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -1.61447
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -1.60248
ZNF287 zinc finger protein 287 -1.59824
TBC1D5 TBC1 domain family, member 5 -1.5968
NBEA neurobeachin -1.59662
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G -1.58723
ACLY ATP citrate lyase -1.58678
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -1.58447
L3MBTL1 l(3)mbt-like 1 (Drosophila) -1.58345
ZNF749 zinc finger protein 749 -1.58184
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -1.58139
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -1.57825
DSPP dentin sialophosphoprotein -1.57805
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -1.57447
OSBP oxysterol binding protein -1.56426
TMX2 thioredoxin-related transmembrane protein 2 -1.55839
PADI4 peptidyl arginine deiminase, type IV -1.55634
EPHB1 EPH receptor B1 -1.55229
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -1.55191
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -1.5509
ADRA2C adrenoceptor alpha 2C -1.54803
PDE12 phosphodiesterase 12 -1.54761
EMD emerin -1.54616
PPME1 protein phosphatase methylesterase 1 -1.5457
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -1.54492
GMEB2 glucocorticoid modulatory element binding protein 2 -1.54492
ZNF14 zinc finger protein 14 -1.54274
SLC17A4 solute carrier family 17, member 4 -1.53036
UNC119 unc-119 homolog (C. elegans) -1.52907
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -1.52906
SAC3D1 SAC3 domain containing 1 -1.52765
F7 coagulation factor VII (serum prothrombin conversion accelerator) -1.52649
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -1.52556
DCP1A decapping mRNA 1A -1.5111
GOLGA8A golgin A8 family, member A -1.50861
GARS glycyl-tRNA synthetase -1.50501
RNF123 ring finger protein 123 -1.50296
KMT2A lysine (K)-specific methyltransferase 2A -1.50145
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -1.49737
RNFT2 ring finger protein, transmembrane 2 -1.49177
POLI polymerase (DNA directed) iota -1.49175
RAB6A RAB6A, member RAS oncogene family -1.48376
STX11 syntaxin 11 -1.47956
WDR74 WD repeat domain 74 -1.4781
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -1.47784
YARS tyrosyl-tRNA synthetase -1.47396
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.4687
MRPL20 mitochondrial ribosomal protein L20 -1.46572
RGS5 regulator of G-protein signaling 5 -1.46538
PPP2R5B protein phosphatase 2, regulatory subunit B', beta -1.45908
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -1.45438
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -1.45238
FCAR Fc fragment of IgA receptor -1.44985
ING1 inhibitor of growth family, member 1 -1.44224
NXPH4 neurexophilin 4 -1.43603
SSRP1 structure specific recognition protein 1 -1.43519
ATXN2L ataxin 2-like -1.43506
DDR2 discoidin domain receptor tyrosine kinase 2 -1.43301
HIST1H1D histone cluster 1, H1d -1.42874
ORAI2 ORAI calcium release-activated calcium modulator 2 -1.42854
USF2 upstream transcription factor 2, c-fos interacting -1.42829
PARK2 parkin RBR E3 ubiquitin protein ligase -1.42808
CELA3A chymotrypsin-like elastase family, member 3A -1.42358
DCAF4 DDB1 and CUL4 associated factor 4 -1.42322
ZNF767P zinc finger family member 767, pseudogene -1.42232
SYNGR4 synaptogyrin 4 -1.4213
SNX15 sorting nexin 15 -1.42033
RBM10 RNA binding motif protein 10 -1.4176
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) -1.41711
SLC25A38 solute carrier family 25, member 38 -1.41643