SYT4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description synaptotagmin IV| (NCBI Entrez Gene Database, 6860)
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Genes

330 genes differentially expressed following the SYT4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 3.63184
SMC1B structural maintenance of chromosomes 1B 3.63184
PRAM1 PML-RARA regulated adaptor molecule 1 3.63184
MORN5 MORN repeat containing 5 3.63184
COL20A1 collagen, type XX, alpha 1 3.63184
TMIGD2 transmembrane and immunoglobulin domain containing 2 3.63184
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.63184
LEKR1 leucine, glutamate and lysine rich 1 3.63184
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 3.63184
C19ORF38 chromosome 19 open reading frame 38 3.63184
CORO6 coronin 6 3.63184
ABHD15 abhydrolase domain containing 15 3.63184
SHISA3 shisa family member 3 3.63184
FGF20 fibroblast growth factor 20 3.63184
DHRS9 dehydrogenase/reductase (SDR family) member 9 3.63184
SPAAR small regulatory polypeptide of amino acid response 3.63184
GREP1 glycine rich extracellular protein 1 3.63184
TMEM132E transmembrane protein 132E 3.63184
MARCHF10 membrane associated ring-CH-type finger 10 3.63184
HJV hemojuvelin BMP co-receptor 3.63184
S100A14 S100 calcium binding protein A14 3.63184
CATSPER4 cation channel, sperm associated 4 3.63184
OTX1 orthodenticle homeobox 1 3.63184
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 3.60114
SP7 Sp7 transcription factor 3.60114
ARSF arylsulfatase F 3.60114
CRYL1 crystallin, lambda 1 3.60114
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.60114
ZNF662 zinc finger protein 662 3.60114
MYBPC1 myosin binding protein C, slow type 3.60114
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.60114
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.60114
TMEM191B transmembrane protein 191B 3.60114
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.60114
PDE7B phosphodiesterase 7B 3.60114
DRP2 dystrophin related protein 2 3.60114
C1ORF146 chromosome 1 open reading frame 146 3.60114
MYO1A myosin IA 3.60114
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 3.60114
GYS2 glycogen synthase 2 (liver) 3.60114
VSIG2 V-set and immunoglobulin domain containing 2 3.60114
MYL7 myosin, light chain 7, regulatory 3.60114
TPPP tubulin polymerization promoting protein 3.60114
THEMIS thymocyte selection associated 3.60114
LHX1 LIM homeobox 1 3.60114
CYSRT1 cysteine-rich tail protein 1 3.60114
RLN1 relaxin 1 3.60114
SPHK1 sphingosine kinase 1 3.60114
OR1L8 olfactory receptor, family 1, subfamily L, member 8 3.60114
MROH2B maestro heat-like repeat family member 2B 3.60114
ATP8B4 ATPase, class I, type 8B, member 4 3.60114
C8ORF74 chromosome 8 open reading frame 74 3.60114
OXT oxytocin/neurophysin I prepropeptide 3.60114
TAS2R19 taste receptor, type 2, member 19 3.60114
MYO16 myosin XVI 3.60114
GALR2 galanin receptor 2 3.60114
FXYD2 FXYD domain containing ion transport regulator 2 3.60114
DRC5 dynein regulatory complex subunit 5 3.60114
OR51M1 olfactory receptor, family 51, subfamily M, member 1 3.60114
REP15 RAB15 effector protein 3.60114
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 3.60114
CLEC6A C-type lectin domain family 6, member A 3.60114
PRDM6 PR domain containing 6 3.60114
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.60114
ASIC3 acid sensing (proton gated) ion channel 3 3.60114
IL7R interleukin 7 receptor 3.60114
TSPAN8 tetraspanin 8 3.60114
WNT16 wingless-type MMTV integration site family, member 16 3.60114
BDKRB1 bradykinin receptor B1 3.60114
NPIPA6 nuclear pore complex interacting protein family, member A6 3.60114
CATSPERZ catsper channel auxiliary subunit zeta 3.60114
CBLIF cobalamin binding intrinsic factor 3.60114
TBXT T-box transcription factor T 3.60114
TMOD1 tropomodulin 1 3.60114
SAPCD1 suppressor APC domain containing 1 3.60114
LTB4R2 leukotriene B4 receptor 2 3.60114
SPEM1 spermatid maturation 1 3.60114
BLNK B-cell linker 3.60114
C6ORF118 chromosome 6 open reading frame 118 3.60114
C1QL2 complement component 1, q subcomponent-like 2 3.60114
GPR6 G protein-coupled receptor 6 3.60114
TMPRSS11F transmembrane protease, serine 11F 3.60114
TMPRSS11A transmembrane protease, serine 11A 3.60114
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 3.60114
SOX1 SRY (sex determining region Y)-box 1 3.60114
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.60114
FAM167B family with sequence similarity 167, member B 3.60114
SCN2B sodium channel, voltage gated, type II beta subunit 3.60114
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 3.60114
TAS2R3 taste receptor, type 2, member 3 3.60114
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.60114
CFAP45 cilia and flagella associated protein 45 3.60114
TLR3 toll-like receptor 3 3.60114
SIM2 single-minded family bHLH transcription factor 2 3.60114
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.60114
NKX2-6 NK2 homeobox 6 3.60114
PCDHA3 protocadherin alpha 3 3.60114
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 3.60114
PVRIG poliovirus receptor related immunoglobulin domain containing 3.60114
LRRTM1 leucine rich repeat transmembrane neuronal 1 3.60114
DRD2 dopamine receptor D2 3.60114
PCP2 Purkinje cell protein 2 3.60114
LRRIQ3 leucine-rich repeats and IQ motif containing 3 3.60114
WFDC9 WAP four-disulfide core domain 9 3.60114
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 3.60114
CPA3 carboxypeptidase A3 (mast cell) 3.60114
IL36R interleukin 36 receptor 3.60114
PCDHGA7 protocadherin gamma subfamily A, 7 3.60114
ISL2 ISL LIM homeobox 2 3.60114
NOX1 NADPH oxidase 1 3.60114
HSPA1L heat shock 70kDa protein 1-like 3.60114
IL17REL interleukin 17 receptor E-like 3.60114
CCL25 chemokine (C-C motif) ligand 25 3.60114
NLRC3 NLR family, CARD domain containing 3 3.60114
LCT lactase 3.60114
EFCAB9 EF-hand calcium binding domain 9 3.60114
DPRX divergent-paired related homeobox 3.60114
CXCR6 chemokine (C-X-C motif) receptor 6 3.60114
CTAGE9 CTAGE family, member 9 3.60114
IL19 interleukin 19 3.60114
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 3.60114
CT55 cancer/testis antigen 55 3.60114
SLC38A8 solute carrier family 38, member 8 3.60114
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.60114
IGIP IgA-inducing protein 3.60114
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 3.60114
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.60114
HPGDS hematopoietic prostaglandin D synthase 3.60114
OPALIN oligodendrocytic myelin paranodal and inner loop protein 3.60114
GOLGA8R golgin A8 family, member R 3.60114
CISH cytokine inducible SH2-containing protein 3.60114
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 3.60114
SIAH3 siah E3 ubiquitin protein ligase family member 3 3.60114
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 3.60114
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.60114
OCM oncomodulin 3.60114
PLCL1 phospholipase C-like 1 3.60114
ZGLP1 zinc finger, GATA-like protein 1 3.60114
EPHA5 EPH receptor A5 3.60114
PDCD1LG2 programmed cell death 1 ligand 2 3.60114
ART1 ADP-ribosyltransferase 1 3.60114
POU3F2 POU class 3 homeobox 2 3.60114
ALOX15B arachidonate 15-lipoxygenase, type B 3.60114
SUN3 Sad1 and UNC84 domain containing 3 3.60114
R3HDML R3H domain containing-like 3.60114
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 3.60114
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.60114
TMEM86A transmembrane protein 86A 3.60114
PTCRA pre T-cell antigen receptor alpha 3.60114
CHRDL2 chordin-like 2 3.60114
MMP12 matrix metallopeptidase 12 3.60114
ANGPTL6 angiopoietin-like 6 3.60114
A1CF APOBEC1 complementation factor 3.60114
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 3.60114
ANXA1 annexin A1 3.60114
IRX5 iroquois homeobox 5 3.60114
ECM1 extracellular matrix protein 1 3.60114
WFDC13 WAP four-disulfide core domain 13 3.60114
GALP galanin-like peptide 3.60114
AGR2 anterior gradient 2 3.60114
PADI3 peptidyl arginine deiminase, type III 3.60114
NFE2 nuclear factor, erythroid 2 3.60114
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 3.60114
PADI4 peptidyl arginine deiminase, type IV 3.60114
PCDH20 protocadherin 20 3.52667
NLRP1 NLR family, pyrin domain containing 1 3.52667
TRPM6 transient receptor potential cation channel, subfamily M, member 6 3.52667
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 3.36677
MIA2 melanoma inhibitory activity 2 3.25547
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 3.11693
PDZD4 PDZ domain containing 4 3.10901
EFR3A EFR3 homolog A (S. cerevisiae) 2.99923
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.82329
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 2.8125
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.79313
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.7077
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 2.68238
CEP112 centrosomal protein 112kDa 2.68238
MCM10 minichromosome maintenance complex component 10 2.60466
SCLY selenocysteine lyase 2.53377
GLYATL2 glycine-N-acyltransferase-like 2 2.52177
UBTF upstream binding transcription factor, RNA polymerase I 2.50873
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.48502
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 2.48472
DRC10 dynein regulatory complex subunit 10 2.48472
DUSP13B dual specificity phosphatase 13B 2.48472
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.48471
ZNF600 zinc finger protein 600 2.46154
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.43661
ZBTB40 zinc finger and BTB domain containing 40 2.38044
TTC7A tetratricopeptide repeat domain 7A 2.34988
AGGF1 angiogenic factor with G patch and FHA domains 1 2.34264
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.33527
SUMF1 sulfatase modifying factor 1 2.28874
LACTB lactamase, beta 2.28549
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.28549
PNPLA3 patatin-like phospholipase domain containing 3 2.2824
CYTH3 cytohesin 3 2.2577
WDR20 WD repeat domain 20 2.25561
ABHD8 abhydrolase domain containing 8 2.24633
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.22887
SYT6 synaptotagmin VI 2.21594
NREP neuronal regeneration related protein 2.21594
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.21544
MIB1 mindbomb E3 ubiquitin protein ligase 1 2.20949
UNC79 unc-79 homolog (C. elegans) 2.19567
COL16A1 collagen, type XVI, alpha 1 2.18506
GPX8 glutathione peroxidase 8 (putative) 2.17905
SLC39A10 solute carrier family 39 (zinc transporter), member 10 2.17856
RNF13 ring finger protein 13 2.16999
NALF2 NALCN channel auxiliary factor 2 2.12012
LIPE lipase, hormone-sensitive 2.11977
SSH3 slingshot protein phosphatase 3 2.08708
UBOX5 U-box domain containing 5 2.06295
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 2.05767
LURAP1 leucine rich adaptor protein 1 2.04841
DKKL1 dickkopf-like 1 2.00942
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2.00845
H2BC17 H2B clustered histone 17 2.00603
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 2.00047
FDXACB1 ferredoxin-fold anticodon binding domain containing 1 2.00047
STMN2 stathmin 2 2.00047

decreased expression

Symbol Name Standardized Value
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) -3.63184
ZNF862 zinc finger protein 862 -3.63184
CCDC159 coiled-coil domain containing 159 -3.62113
PADI2 peptidyl arginine deiminase, type II -3.62113
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -3.62113
ANKRD61 ankyrin repeat domain 61 -3.60114
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -3.60114
PP2D1 protein phosphatase 2C-like domain containing 1 -3.60114
LYG2 lysozyme G-like 2 -3.60114
LBHD1 LBH domain containing 1 -3.60114
TLR5 toll-like receptor 5 -3.60114
TMEM121 transmembrane protein 121 -3.60114
EBF3 early B-cell factor 3 -3.60114
TEX101 testis expressed 101 -3.60114
ZMYND12 zinc finger, MYND-type containing 12 -3.60114
SFN stratifin -3.60114
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 -3.60114
GSTM3 glutathione S-transferase mu 3 (brain) -3.60114
BMP8A bone morphogenetic protein 8a -3.60114
TEKT3 tektin 3 -3.60114
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -3.60114
ARC activity-regulated cytoskeleton-associated protein -3.60114
ACP3 acid phosphatase 3 -3.60114
ADAP1 ArfGAP with dual PH domains 1 -3.60114
PRR22 proline rich 22 -3.60114
PIERCE2 piercer of microtubule wall 2 -3.60114
PLA2G2C phospholipase A2, group IIC -3.60114
CRACDL CRACD like -3.60114
NPM2 nucleophosmin/nucleoplasmin 2 -3.60114
PCDHGA9 protocadherin gamma subfamily A, 9 -3.60114
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 -3.60114
ITGA11 integrin, alpha 11 -3.60114
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -3.5673
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -3.46448
KLB klotho beta -3.45185
ZNF516 zinc finger protein 516 -3.44372
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -3.35288
DMXL2 Dmx-like 2 -3.17565
KDM3B lysine (K)-specific demethylase 3B -3.07316
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -2.94994
ZNF33B zinc finger protein 33B -2.92971
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -2.89108
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.84933
SLC25A43 solute carrier family 25, member 43 -2.84043
REEP6 receptor accessory protein 6 -2.8123
IKBIP IKBKB interacting protein -2.77228
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -2.75069
ZUP1 zinc finger containing ubiquitin peptidase 1 -2.64745
PANK1 pantothenate kinase 1 -2.64745
NRCAM neuronal cell adhesion molecule -2.53668
RNF32 ring finger protein 32 -2.52177
WNT5B wingless-type MMTV integration site family, member 5B -2.50232
MXRA8 matrix-remodelling associated 8 -2.50232
NME8 NME/NM23 family member 8 -2.42055
HRH3 histamine receptor H3 -2.42055
ZNF225 zinc finger protein 225 -2.42055
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 -2.42055
ZNF346 zinc finger protein 346 -2.42055
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like -2.42055
MPZ myelin protein zero -2.42055
GLRB glycine receptor, beta -2.42055
MMP26 matrix metallopeptidase 26 -2.42055
RPL7 ribosomal protein L7 -2.41507
CASKIN2 CASK interacting protein 2 -2.41408
RPS15 ribosomal protein S15 -2.40955
EIF3I eukaryotic translation initiation factor 3, subunit I -2.40492
LRRC42 leucine rich repeat containing 42 -2.36412
HSPA4 heat shock 70kDa protein 4 -2.35237
RGS6 regulator of G-protein signaling 6 -2.34945
MAPK12 mitogen-activated protein kinase 12 -2.31846
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.30576
WDR86 WD repeat domain 86 -2.29655
FBXO43 F-box protein 43 -2.28874
NECAB3 N-terminal EF-hand calcium binding protein 3 -2.28874
ERMP1 endoplasmic reticulum metallopeptidase 1 -2.28832
ENO1 enolase 1, (alpha) -2.28549
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -2.25228
CALCOCO1 calcium binding and coiled-coil domain 1 -2.24532
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -2.23777
ADPRHL1 ADP-ribosylhydrolase like 1 -2.23777
FNBP4 formin binding protein 4 -2.23777
HAP1 huntingtin-associated protein 1 -2.23777
SH3BP5L SH3-binding domain protein 5-like -2.23426
SNRPF small nuclear ribonucleoprotein polypeptide F -2.23426
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.23269
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 -2.22952
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.21544
ADGRG5 adhesion G protein-coupled receptor G5 -2.21237
ATG3 autophagy related 3 -2.20949
IGSF1 immunoglobulin superfamily, member 1 -2.19129
KIF6 kinesin family member 6 -2.18983
ELP5 elongator acetyltransferase complex subunit 5 -2.18613
RPL35A ribosomal protein L35a -2.17511
TMED1 transmembrane emp24 protein transport domain containing 1 -2.16707
MAP7D2 MAP7 domain containing 2 -2.14295
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.12012
ZFP82 ZFP82 zinc finger protein -2.11977
PAN3 PAN3 poly(A) specific ribonuclease subunit -2.10262
PRRC2C proline-rich coiled-coil 2C -2.08836
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -2.0873
SRPRB signal recognition particle receptor, B subunit -2.08708
TENT5B terminal nucleotidyltransferase 5B -2.08271
ITSN1 intersectin 1 (SH3 domain protein) -2.08241
C14ORF93 chromosome 14 open reading frame 93 -2.08117
PLSCR3 phospholipid scramblase 3 -2.05869
GEMIN7 gem (nuclear organelle) associated protein 7 -2.05767
CCDC149 coiled-coil domain containing 149 -2.05767
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B -2.04653