SYT4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description synaptotagmin IV| (NCBI Entrez Gene Database, 6860)
External Link https://ncbi.nlm.nih.gov/gene/6860
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Genes

500 genes differentially expressed following the SYT4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0187844
PLAAT3 phospholipase A and acyltransferase 3 0.0152088
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0134416
PERP PERP, TP53 apoptosis effector 0.0130301
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0118259
ISG15 ISG15 ubiquitin-like modifier 0.0113939
CCNG2 cyclin G2 0.0113624
AMDHD2 amidohydrolase domain containing 2 0.0113596
IFI6 interferon, alpha-inducible protein 6 0.0113301
MGLL monoglyceride lipase 0.011209
MTCL1 microtubule crosslinking factor 1 0.0110899
APOD apolipoprotein D 0.0109296
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.0103825
KRT7 keratin 7, type II 0.0102511
COL15A1 collagen, type XV, alpha 1 0.010088
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.0100531
SCGB1D2 secretoglobin, family 1D, member 2 0.0100108
AMIGO2 adhesion molecule with Ig-like domain 2 0.00993448
PMP22 peripheral myelin protein 22 0.00990026
IPO13 importin 13 0.00989092
ACTN4 actinin, alpha 4 0.00970444
STK39 serine threonine kinase 39 0.00960421
HSPA1A heat shock 70kDa protein 1A 0.00956913
MVP major vault protein 0.00948348
MX1 MX dynamin-like GTPase 1 0.00930205
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00918216
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00917025
FNDC3B fibronectin type III domain containing 3B 0.00914738
FBLN2 fibulin 2 0.00913709
PLAU plasminogen activator, urokinase 0.00907601
SPON2 spondin 2, extracellular matrix protein 0.00893051
TGFA transforming growth factor, alpha 0.00890761
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.0087899
CLTB clathrin, light chain B 0.00876933
PILRB paired immunoglobin-like type 2 receptor beta 0.00874928
LY6E lymphocyte antigen 6 complex, locus E 0.00865121
BIK BCL2-interacting killer (apoptosis-inducing) 0.00863491
KRT19 keratin 19, type I 0.00861793
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00860542
MTUS1 microtubule associated tumor suppressor 1 0.00860293
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00857075
DAPK1 death-associated protein kinase 1 0.00856363
SDC4 syndecan 4 0.00854344
PPL periplakin 0.00853685
CTSA cathepsin A 0.0085317
DPP4 dipeptidyl-peptidase 4 0.00852281
CDC34 cell division cycle 34 0.00850774
AKR1C3 aldo-keto reductase family 1, member C3 0.00848913
KLK5 kallikrein-related peptidase 5 0.008469
CLEC3B C-type lectin domain family 3, member B 0.00834787
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00834316
RBM47 RNA binding motif protein 47 0.00831564
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.0083001
COL6A2 collagen, type VI, alpha 2 0.00826005
KRT17 keratin 17, type I 0.00822994
CCN3 cellular communication network factor 3 0.00821958
ANPEP alanyl (membrane) aminopeptidase 0.00819573
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00817594
MX2 MX dynamin-like GTPase 2 0.0081535
AKR1C1 aldo-keto reductase family 1, member C1 0.00808661
TUBB2A tubulin, beta 2A class IIa 0.00808294
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00797923
BSG basigin (Ok blood group) 0.00787582
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00780628
FST follistatin 0.00780544
GPI glucose-6-phosphate isomerase 0.00779295
MXRA7 matrix-remodelling associated 7 0.00779226
RBPMS RNA binding protein with multiple splicing 0.00771058
HIP1R huntingtin interacting protein 1 related 0.00768687
HSPB1 heat shock 27kDa protein 1 0.00766571
NT5E 5'-nucleotidase, ecto (CD73) 0.00765463
IRF7 interferon regulatory factor 7 0.00764442
PLXNB2 plexin B2 0.00760607
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00758105
TACSTD2 tumor-associated calcium signal transducer 2 0.00757187
AMOTL2 angiomotin like 2 0.00754184
ENAH enabled homolog (Drosophila) 0.0075406
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00752115
IFI27 interferon, alpha-inducible protein 27 0.00752084
PLXND1 plexin D1 0.00751188
LPIN1 lipin 1 0.00748315
HMOX1 heme oxygenase 1 0.00746693
GSTP1 glutathione S-transferase pi 1 0.00745104
ACADVL acyl-CoA dehydrogenase, very long chain 0.00742783
BASP1 brain abundant, membrane attached signal protein 1 0.00741559
DSP desmoplakin 0.00736586
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00731233
PEG10 paternally expressed 10 0.00731103
ADM adrenomedullin 0.00730379
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.00728362
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00727089
RND3 Rho family GTPase 3 0.0072705
ANGPTL4 angiopoietin-like 4 0.00726323
ZDHHC11 zinc finger, DHHC-type containing 11 0.00725242
AKR1C2 aldo-keto reductase family 1, member C2 0.00722506
STIP1 stress-induced phosphoprotein 1 0.00719547
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00717039
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 0.00713106
TXN thioredoxin 0.00712786
SH3BP4 SH3-domain binding protein 4 0.00712575
PRSS3 protease, serine, 3 0.00711335
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00707004
FBLN1 fibulin 1 0.00705447
KRT18 keratin 18, type I 0.00700526
BRD4 bromodomain containing 4 0.00700128
PLXNA1 plexin A1 0.0069921
KIAA0930 KIAA0930 0.00698331
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00695204
RHOD ras homolog family member D 0.00694895
PLPP2 phospholipid phosphatase 2 0.00694745
BAD BCL2-associated agonist of cell death 0.00693619
FADS3 fatty acid desaturase 3 0.0069132
HOMER3 homer scaffolding protein 3 0.00690772
BIN1 bridging integrator 1 0.00689675
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00685456
RRAGC Ras-related GTP binding C 0.00685448
PDLIM2 PDZ and LIM domain 2 (mystique) 0.0068544
C21ORF91 chromosome 21 open reading frame 91 0.0068435
KLK11 kallikrein-related peptidase 11 0.00680131
KRT8 keratin 8, type II 0.00678894
LAMB1 laminin, beta 1 0.00677819
EZR ezrin 0.00675873
HSPB8 heat shock 22kDa protein 8 0.00675757
TIMP1 TIMP metallopeptidase inhibitor 1 0.0067321
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.00672246
IL6R interleukin 6 receptor 0.00671156
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0067012
TGFBR3 transforming growth factor, beta receptor III 0.00669452
MMP2 matrix metallopeptidase 2 0.0066877
F13A1 coagulation factor XIII, A1 polypeptide 0.0066559
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.0066401
GJA1 gap junction protein, alpha 1, 43kDa 0.00662122
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.00660983
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00660943
S100A11 S100 calcium binding protein A11 0.0066051
UBA1 ubiquitin-like modifier activating enzyme 1 0.00652689
RTN2 reticulon 2 0.00649712
SQSTM1 sequestosome 1 0.00647514
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.00644687
HLA-B major histocompatibility complex, class I, B 0.00643936
KRT23 keratin 23, type I 0.00643671
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.0064347
RGS16 regulator of G-protein signaling 16 0.00641728
KIF13B kinesin family member 13B 0.00640812
TNS3 tensin 3 0.0064022
SPATA20 spermatogenesis associated 20 0.00639329
DYNLL1 dynein, light chain, LC8-type 1 0.00636652
PKM pyruvate kinase, muscle 0.00634191
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.00633435
IGF2R insulin-like growth factor 2 receptor 0.00632228
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00631896
PLK2 polo-like kinase 2 0.00630079
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00629422
FHL2 four and a half LIM domains 2 0.0062718
HIST1H2BK histone cluster 1, H2bk 0.00625111
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 0.00624324
TRIM28 tripartite motif containing 28 0.00623156
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00622512
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00621011
FSTL1 follistatin-like 1 0.00620333
CST6 cystatin E/M 0.00620311
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.00618882
CRCT1 cysteine-rich C-terminal 1 0.00618714
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00618294
GRAMD4 GRAM domain containing 4 0.00617857
ADCY9 adenylate cyclase 9 0.00616711
ACTB actin, beta 0.00616582
EPS8 epidermal growth factor receptor pathway substrate 8 0.00615289
DBN1 drebrin 1 0.00613396
NXN nucleoredoxin 0.00611566
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00611501
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00610158
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00610005
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00609604
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00607528
CCNL2 cyclin L2 0.00607507
MIR22HG MIR22 host gene 0.00606998
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.00606631
OSR2 odd-skipped related transciption factor 2 0.0060572
DST dystonin 0.00603143
MAP2K2 mitogen-activated protein kinase kinase 2 0.00602699
ABHD17A abhydrolase domain containing 17A 0.00602558
COL4A2 collagen, type IV, alpha 2 0.00602133
TFPI2 tissue factor pathway inhibitor 2 0.00602101
CEL carboxyl ester lipase 0.00600717
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00599474
MARK2 MAP/microtubule affinity-regulating kinase 2 0.00598279
KLK10 kallikrein-related peptidase 10 0.0059753
STX3 syntaxin 3 0.0059727
INHBB inhibin, beta B 0.0059701
TM4SF4 transmembrane 4 L six family member 4 0.00594113
FAM50A family with sequence similarity 50, member A 0.00593495
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.0059341
CADM1 cell adhesion molecule 1 0.0059316
BCL3 B-cell CLL/lymphoma 3 0.0059313
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00592698
SAMD9 sterile alpha motif domain containing 9 0.00592167
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0059204
ZNF395 zinc finger protein 395 0.00591846
MXD4 MAX dimerization protein 4 0.00589477
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00587853
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.00587744
MITF microphthalmia-associated transcription factor 0.00586366
PLIN2 perilipin 2 0.00585608
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00584975
KLF13 Kruppel-like factor 13 0.00584199
SYNGR3 synaptogyrin 3 0.00581959
COMP cartilage oligomeric matrix protein 0.005817
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00581184
MAP7D1 MAP7 domain containing 1 0.00581054
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00580978
ANKRD11 ankyrin repeat domain 11 0.00580857
SCARB1 scavenger receptor class B, member 1 0.00580257
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00579507
MBNL2 muscleblind-like splicing regulator 2 0.0057913
RTL8C retrotransposon Gag like 8C 0.005776
MALL mal, T-cell differentiation protein-like 0.00577174
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00576275
VCL vinculin 0.00575799
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.005754
IL1RN interleukin 1 receptor antagonist 0.00574887
WASF1 WAS protein family, member 1 0.0057392
SETD5 SET domain containing 5 0.00573688
SBF1 SET binding factor 1 0.0057293
JUP junction plakoglobin 0.00571859
COL3A1 collagen, type III, alpha 1 0.0057101
EIF5B eukaryotic translation initiation factor 5B 0.00571
PRSS23 protease, serine, 23 0.00569639
ZNF281 zinc finger protein 281 0.00569343
RAP1GAP2 RAP1 GTPase activating protein 2 0.00568643
ECM1 extracellular matrix protein 1 0.00568624
SLC38A2 solute carrier family 38, member 2 0.00568113
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.00568007
MET MET proto-oncogene, receptor tyrosine kinase 0.00567947
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.00567085
JPT1 Jupiter microtubule associated homolog 1 0.00566603
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00566314
CLUH clustered mitochondria (cluA/CLU1) homolog 0.00565535
SEPP1 selenoprotein P, plasma, 1 0.00564406
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.00563003
SLC12A9 solute carrier family 12, member 9 0.00561673
PRKCZ protein kinase C, zeta 0.0056107
ADRM1 adhesion regulating molecule 1 0.00560724
CTSV cathepsin V 0.00560697
BST2 bone marrow stromal cell antigen 2 0.0055969
NBPF10 neuroblastoma breakpoint family, member 10 0.00559505
TUFT1 tuftelin 1 0.00558755
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00557652
PRSS8 protease, serine, 8 0.00557538
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00557461

decreased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0245216
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0134848
NELL2 NEL-like 2 (chicken) -0.0125165
CD52 CD52 molecule -0.01143
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0108162
RGS1 regulator of G-protein signaling 1 -0.0102389
ESR1 estrogen receptor 1 -0.0102077
RBM34 RNA binding motif protein 34 -0.010114
ANOS1 anosmin 1 -0.0099241
C7 complement component 7 -0.00987699
GPM6B glycoprotein M6B -0.00985848
ARMCX2 armadillo repeat containing, X-linked 2 -0.00946351
DPYD dihydropyrimidine dehydrogenase -0.00934542
TAL1 T-cell acute lymphocytic leukemia 1 -0.00927899
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00923381
PCP4 Purkinje cell protein 4 -0.00911291
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00899629
LAPTM5 lysosomal protein transmembrane 5 -0.00898446
SRGN serglycin -0.00886122
CCNA2 cyclin A2 -0.00881551
OLFM1 olfactomedin 1 -0.00877319
LXN latexin -0.00871485
GMFG glia maturation factor, gamma -0.0087085
CETN2 centrin, EF-hand protein, 2 -0.0085933
GPM6A glycoprotein M6A -0.00857371
CD9 CD9 molecule -0.00852089
ENO2 enolase 2 (gamma, neuronal) -0.00850545
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00843327
COG7 component of oligomeric golgi complex 7 -0.00838814
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00838742
TMEM255A transmembrane protein 255A -0.00833395
ITM2A integral membrane protein 2A -0.00825041
RPA3 replication protein A3, 14kDa -0.00821584
TMEM100 transmembrane protein 100 -0.0080852
PRKCA protein kinase C, alpha -0.00802352
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00801138
NEBL nebulette -0.00797501
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0079432
KIF5C kinesin family member 5C -0.00790848
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00787735
ZBED8 zinc finger, BED-type containing 8 -0.00781209
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00779563
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00779275
KIF15 kinesin family member 15 -0.0077482
SELL selectin L -0.00773527
GSAP gamma-secretase activating protein -0.00767614
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00764059
IL2RG interleukin 2 receptor, gamma -0.00761527
CD69 CD69 molecule -0.00760345
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00757108
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00756465
GAP43 growth associated protein 43 -0.0075365
KIF20A kinesin family member 20A -0.00751955
OIP5 Opa interacting protein 5 -0.00751091
CHI3L2 chitinase 3-like 2 -0.00745583
PBX1 pre-B-cell leukemia homeobox 1 -0.00744504
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00744265
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00744209
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.00742935
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00737876
NSL1 NSL1, MIS12 kinetochore complex component -0.00736173
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00731137
GIMAP6 GTPase, IMAP family member 6 -0.00730345
FAM107A family with sequence similarity 107, member A -0.00724606
ICAM2 intercellular adhesion molecule 2 -0.00724442
NEK2 NIMA-related kinase 2 -0.0072159
HMGB2 high mobility group box 2 -0.00717134
EMP2 epithelial membrane protein 2 -0.00715689
PRUNE2 prune homolog 2 (Drosophila) -0.00715493
FAR2 fatty acyl CoA reductase 2 -0.00706719
VRK1 vaccinia related kinase 1 -0.0070486
MRTFB myocardin related transcription factor B -0.00703763
PLP1 proteolipid protein 1 -0.00701074
DET1 de-etiolated homolog 1 (Arabidopsis) -0.00698466
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00698247
FAM171A1 family with sequence similarity 171, member A1 -0.00696134
CCDC47 coiled-coil domain containing 47 -0.00692143
FAM46C family with sequence similarity 46, member C -0.00690281
LTA4H leukotriene A4 hydrolase -0.00689888
FXYD6 FXYD domain containing ion transport regulator 6 -0.00689403
RGS4 regulator of G-protein signaling 4 -0.00687617
TRMT5 tRNA methyltransferase 5 -0.00685431
PRKCB protein kinase C, beta -0.00681758
TEK TEK tyrosine kinase, endothelial -0.00681035
LIPT1 lipoyltransferase 1 -0.0068046
PRKCQ protein kinase C, theta -0.00679991
OCRL oculocerebrorenal syndrome of Lowe -0.00678788
GSTO1 glutathione S-transferase omega 1 -0.00676735
THBD thrombomodulin -0.00668622
NTS neurotensin -0.00665174
SERINC5 serine incorporator 5 -0.00663888
NAP1L2 nucleosome assembly protein 1-like 2 -0.00663163
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00661282
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.00659518
MLH1 mutL homolog 1 -0.00658843
CHEK2 checkpoint kinase 2 -0.00658604
CHIT1 chitinase 1 (chitotriosidase) -0.00658258
DHFR dihydrofolate reductase -0.00658165
GIMAP4 GTPase, IMAP family member 4 -0.00657391
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00656781
DCXR dicarbonyl/L-xylulose reductase -0.00656619
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -0.00656521
PDE4B phosphodiesterase 4B, cAMP-specific -0.00656484
GLOD4 glyoxalase domain containing 4 -0.00655768
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00651173
MAP2K5 mitogen-activated protein kinase kinase 5 -0.00649089
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00649046
BIRC5 baculoviral IAP repeat containing 5 -0.00648575
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00648335
EAPP E2F-associated phosphoprotein -0.00646298
THYN1 thymocyte nuclear protein 1 -0.00646005
PIR pirin (iron-binding nuclear protein) -0.00644742
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00644218
PID1 phosphotyrosine interaction domain containing 1 -0.00642942
NAE1 NEDD8 activating enzyme E1 subunit 1 -0.00641428
CCNE2 cyclin E2 -0.00640285
AQP4 aquaporin 4 -0.00638132
MSLN mesothelin -0.00637515
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00637116
MATN2 matrilin 2 -0.00635679
F8 coagulation factor VIII, procoagulant component -0.00635643
COPS4 COP9 signalosome subunit 4 -0.00633711
NAP1L3 nucleosome assembly protein 1-like 3 -0.00633601
YEATS4 YEATS domain containing 4 -0.00632148
MIS18A MIS18 kinetochore protein A -0.00631114
PSRC1 proline/serine-rich coiled-coil 1 -0.00629496
LZTFL1 leucine zipper transcription factor-like 1 -0.00629373
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.00627765
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.00627618
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.00625948
NUP107 nucleoporin 107kDa -0.00625876
METTL18 methyltransferase like 18 -0.00625201
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.0062485
IL33 interleukin 33 -0.00624546
RTN1 reticulon 1 -0.00623978
HAUS4 HAUS augmin-like complex, subunit 4 -0.00623377
CD83 CD83 molecule -0.00623231
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00619645
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00617968
SCG5 secretogranin V -0.00617525
EPHB2 EPH receptor B2 -0.00616945
GCA grancalcin, EF-hand calcium binding protein -0.00616388
RRM1 ribonucleotide reductase M1 -0.00615648
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 -0.0061377
FANCI Fanconi anemia, complementation group I -0.0061376
CETN3 centrin, EF-hand protein, 3 -0.00613258
CCNF cyclin F -0.00613051
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00612788
SMAD2 SMAD family member 2 -0.00611965
NES nestin -0.00611607
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.00611173
PLN phospholamban -0.00609027
FAM172A family with sequence similarity 172, member A -0.00608885
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.00608782
PMP2 peripheral myelin protein 2 -0.00608691
ALCAM activated leukocyte cell adhesion molecule -0.00606448
DSCC1 DNA replication and sister chromatid cohesion 1 -0.00605223
GLIPR1 GLI pathogenesis-related 1 -0.00604312
C3ORF14 chromosome 3 open reading frame 14 -0.00603732
GOLPH3L golgi phosphoprotein 3-like -0.00603383
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.00600769
RAD51 RAD51 recombinase -0.00600285
SUB1 SUB1 homolog (S. cerevisiae) -0.00600239
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0060007
CES1 carboxylesterase 1 -0.00599747
PCGF2 polycomb group ring finger 2 -0.00598884
FABP7 fatty acid binding protein 7, brain -0.0059836
C12ORF29 chromosome 12 open reading frame 29 -0.00598096
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00596761
DDHD2 DDHD domain containing 2 -0.00596563
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00596026
NPTX2 neuronal pentraxin II -0.00595767
FABP1 fatty acid binding protein 1, liver -0.00595595
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00595369
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -0.0059517
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00594764
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) -0.00593897
ERI2 ERI1 exoribonuclease family member 2 -0.00591317
BCHE butyrylcholinesterase -0.00591038
RPA2 replication protein A2, 32kDa -0.00587896
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00587803
HMGN5 high mobility group nucleosome binding domain 5 -0.00587181
ARL4A ADP-ribosylation factor-like 4A -0.00586184
RHOT1 ras homolog family member T1 -0.00585217
FBP1 fructose-1,6-bisphosphatase 1 -0.00585198
DUOX2 dual oxidase 2 -0.00585162
C1ORF54 chromosome 1 open reading frame 54 -0.00584657
LYZ lysozyme -0.00583567
TSPYL5 TSPY-like 5 -0.00583051
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.00582864
TMEM38B transmembrane protein 38B -0.00582825
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00582762
SATB2 SATB homeobox 2 -0.00582617
ELOVL6 ELOVL fatty acid elongase 6 -0.00582436
EPAS1 endothelial PAS domain protein 1 -0.00581495
TMX1 thioredoxin-related transmembrane protein 1 -0.00580604
KRCC1 lysine-rich coiled-coil 1 -0.00580411
MREG melanoregulin -0.00580175
ATRAID all-trans retinoic acid-induced differentiation factor -0.00579812
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00578857
AGA aspartylglucosaminidase -0.0057828
ARHGAP6 Rho GTPase activating protein 6 -0.00577701
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.00577663
CTSS cathepsin S -0.00577335
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00577129
BCLAF1 BCL2-associated transcription factor 1 -0.00577061
PRIM1 primase, DNA, polypeptide 1 (49kDa) -0.00576604
DBF4 DBF4 zinc finger -0.00575953
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -0.00575874
RNASEH2A ribonuclease H2, subunit A -0.00575477
DOK5 docking protein 5 -0.00574639
APOC2 apolipoprotein C-II -0.00574614
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing -0.00573263
TUBD1 tubulin, delta 1 -0.0057078
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00570361
CDCA4 cell division cycle associated 4 -0.00570277
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -0.00568533
ACAT2 acetyl-CoA acetyltransferase 2 -0.00568242
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00568101
IFT46 intraflagellar transport 46 -0.00568083
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00567825
MYH10 myosin, heavy chain 10, non-muscle -0.00567121
FBXO11 F-box protein 11 -0.00565142
HMGN2 high mobility group nucleosomal binding domain 2 -0.00564527
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.00563214
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00562684
MMP12 matrix metallopeptidase 12 -0.00562425
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.00562114
EXOSC9 exosome component 9 -0.00562044
CRIPT cysteine-rich PDZ-binding protein -0.00560921
TTC19 tetratricopeptide repeat domain 19 -0.00560724
CPE carboxypeptidase E -0.00558108
SPC25 SPC25, NDC80 kinetochore complex component -0.0055797
PLAT plasminogen activator, tissue -0.00557493
BCL2A1 BCL2-related protein A1 -0.00557183
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00557012
TMSB15A thymosin beta 15a -0.00554915
CENPN centromere protein N -0.00554722
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00554464
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00553813
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -0.00551835
ZNF274 zinc finger protein 274 -0.00550601
RNASE6 ribonuclease, RNase A family, k6 -0.00549509
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.00549419
CD27 CD27 molecule -0.00549162
TRIP13 thyroid hormone receptor interactor 13 -0.00548834
IFT52 intraflagellar transport 52 -0.00548781
GEMIN2 gem (nuclear organelle) associated protein 2 -0.00548158
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.005442
IMPACT impact RWD domain protein -0.005435