| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | seizure threshold 2 homolog (mouse)|The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011] (NCBI Entrez Gene Database, 23334) |
| External Link | https://ncbi.nlm.nih.gov/gene/23334 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the SZT2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0162276 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.0150177 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.013556 |
| SIK1 | salt-inducible kinase 1 | 0.0133162 |
| SRGN | serglycin | 0.0129825 |
| LTF | lactotransferrin | 0.0121746 |
| AHSP | alpha hemoglobin stabilizing protein | 0.0117893 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.0117764 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.0117335 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0116659 |
| RNF167 | ring finger protein 167 | 0.0113372 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.011262 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0109576 |
| HBD | hemoglobin, delta | 0.0108879 |
| CST7 | cystatin F (leukocystatin) | 0.0108139 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.010597 |
| IL32 | interleukin 32 | 0.0103468 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0100317 |
| SELENBP1 | selenium binding protein 1 | 0.00997156 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00951562 |
| MMP9 | matrix metallopeptidase 9 | 0.00950699 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00949104 |
| DUSP2 | dual specificity phosphatase 2 | 0.00943135 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00931989 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00930252 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0092989 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00926357 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00923316 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0092072 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00920469 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00916286 |
| IL2RG | interleukin 2 receptor, gamma | 0.00912507 |
| PTK2 | protein tyrosine kinase 2 | 0.00909853 |
| CLC | Charcot-Leyden crystal galectin | 0.00909607 |
| ITK | IL2-inducible T-cell kinase | 0.00906265 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00891006 |
| S100A12 | S100 calcium binding protein A12 | 0.00884089 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00878661 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00875449 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00868885 |
| WT1 | Wilms tumor 1 | 0.00867304 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00865794 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00860904 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00859367 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00858822 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00849468 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00838768 |
| NEBL | nebulette | 0.00835077 |
| RUNX3 | runt-related transcription factor 3 | 0.00832162 |
| ARG1 | arginase 1 | 0.00827676 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00826503 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00819132 |
| VEGFA | vascular endothelial growth factor A | 0.00815558 |
| LY75 | lymphocyte antigen 75 | 0.00812029 |
| BCL2A1 | BCL2-related protein A1 | 0.00811629 |
| EGR3 | early growth response 3 | 0.00806099 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00805506 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00802232 |
| CD8A | CD8a molecule | 0.00791935 |
| MAGEA3 | melanoma antigen family A3 | 0.0078685 |
| TARP | TCR gamma alternate reading frame protein | 0.00783835 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00782083 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00781169 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00780459 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00779062 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00777175 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0077585 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.00774905 |
| EPB42 | erythrocyte membrane protein band 4.2 | 0.00773683 |
| PLAT | plasminogen activator, tissue | 0.00771962 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00771458 |
| IRF8 | interferon regulatory factor 8 | 0.00770484 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00764301 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00762779 |
| LXN | latexin | 0.00760455 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00760275 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.00757585 |
| RGS1 | regulator of G-protein signaling 1 | 0.00754575 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00753289 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00749307 |
| S100A9 | S100 calcium binding protein A9 | 0.00745981 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00742469 |
| TLE4 | transducin-like enhancer of split 4 | 0.00739487 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00735641 |
| IL2RB | interleukin 2 receptor, beta | 0.00735349 |
| WWC3 | WWC family member 3 | 0.00732707 |
| PER1 | period circadian clock 1 | 0.00728446 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00727615 |
| PMEL | premelanosome protein | 0.00726547 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00721921 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00719873 |
| CD247 | CD247 molecule | 0.00719497 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.0071267 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00712506 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.0071233 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.00708817 |
| RBM38 | RNA binding motif protein 38 | 0.00704333 |
| MAP7 | microtubule-associated protein 7 | 0.00703869 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00702628 |
| KRT1 | keratin 1, type II | 0.00701343 |
| CAPN3 | calpain 3, (p94) | 0.00694575 |
| EPHB2 | EPH receptor B2 | 0.00692866 |
| TNC | tenascin C | 0.00692587 |
| LBH | limb bud and heart development | 0.006916 |
| BPI | bactericidal/permeability-increasing protein | 0.00686981 |
| MLPH | melanophilin | 0.00685955 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00683586 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00683166 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00669009 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00668109 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00667268 |
| FLNA | filamin A, alpha | 0.00666853 |
| FOSL2 | FOS-like antigen 2 | 0.00664999 |
| CHKB | choline kinase beta | 0.00662551 |
| ENO3 | enolase 3 (beta, muscle) | 0.00662214 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00662115 |
| TGM2 | transglutaminase 2 | 0.006605 |
| ANXA3 | annexin A3 | 0.00659987 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.0065956 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00659233 |
| ANO10 | anoctamin 10 | 0.0065394 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00653666 |
| TFF1 | trefoil factor 1 | 0.00652812 |
| CCNB2 | cyclin B2 | 0.00652516 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00651767 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.00649991 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0064729 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00642704 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00641754 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.0064163 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00640291 |
| TYRP1 | tyrosinase-related protein 1 | 0.00640162 |
| LCN2 | lipocalin 2 | 0.00638809 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00635548 |
| MPO | myeloperoxidase | 0.00631002 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00629921 |
| IRS2 | insulin receptor substrate 2 | 0.00629627 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.0062952 |
| PRKCA | protein kinase C, alpha | 0.00629152 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00629054 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00628108 |
| CD69 | CD69 molecule | 0.00625835 |
| MMP8 | matrix metallopeptidase 8 | 0.00625301 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00625264 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00623485 |
| EGR2 | early growth response 2 | 0.00622731 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00620883 |
| PKM | pyruvate kinase, muscle | 0.00619633 |
| PAX5 | paired box 5 | 0.00617038 |
| ACP3 | acid phosphatase 3 | 0.00616979 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.00616261 |
| H1-0 | H1.0 linker histone | 0.0061609 |
| ACTN1 | actinin, alpha 1 | 0.00615901 |
| NPR3 | natriuretic peptide receptor 3 | 0.00615767 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00614681 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00614399 |
| RNF144A | ring finger protein 144A | 0.00613122 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00612914 |
| NES | nestin | 0.00610971 |
| SVIL | supervillin | 0.00610211 |
| PLEK | pleckstrin | 0.00608499 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.00607757 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00606347 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00605028 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00604536 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00602449 |
| XPO7 | exportin 7 | 0.00600932 |
| KLF11 | Kruppel-like factor 11 | 0.0060067 |
| COG7 | component of oligomeric golgi complex 7 | 0.00600637 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00600496 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00594807 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00593384 |
| ELANE | elastase, neutrophil expressed | 0.00590414 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.00588709 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.00587112 |
| TATDN2 | TatD DNase domain containing 2 | 0.00586635 |
| BMP2K | BMP2 inducible kinase | 0.00586242 |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) | 0.005838 |
| IL21R | interleukin 21 receptor | 0.00583187 |
| CDHR1 | cadherin-related family member 1 | 0.00582041 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00580279 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00578132 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00576553 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00575799 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00574194 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00573538 |
| HCP5 | HLA complex P5 (non-protein coding) | 0.00572206 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00572118 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00570945 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | 0.00570705 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00570404 |
| SPAG1 | sperm associated antigen 1 | 0.00567329 |
| DENND2B | DENN domain containing 2B | 0.00566467 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 0.00565668 |
| EREG | epiregulin | 0.00564889 |
| NKG7 | natural killer cell granule protein 7 | 0.00564172 |
| XK | X-linked Kx blood group | 0.00561414 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00561076 |
| GOLM1 | golgi membrane protein 1 | 0.00560703 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0056053 |
| CD19 | CD19 molecule | 0.00560028 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0055875 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00557373 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | 0.00556424 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.00554954 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00552819 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00552119 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00551273 |
| PRTN3 | proteinase 3 | 0.00550416 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00549689 |
| JMJD6 | jumonji domain containing 6 | 0.00549399 |
| HMBS | hydroxymethylbilane synthase | 0.00549299 |
| GPM6B | glycoprotein M6B | 0.00548933 |
| XIC | X chromosome inactivation center | 0.00548421 |
| COCH | cochlin | 0.00547473 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00545438 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00544574 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00543527 |
| CAMP | cathelicidin antimicrobial peptide | 0.00542015 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00541797 |
| TNS1 | tensin 1 | 0.00540782 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00539256 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00536974 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00536756 |
| CTSW | cathepsin W | 0.00536695 |
| ATP10D | ATPase, class V, type 10D | 0.0053614 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00535434 |
| THBD | thrombomodulin | 0.00535262 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00534749 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00534118 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00532441 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00532238 |
| RAB38 | RAB38, member RAS oncogene family | 0.00532046 |
| CD83 | CD83 molecule | 0.00530678 |
| PRR15L | proline rich 15-like | 0.0053048 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00529453 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00528747 |
| ORC1 | origin recognition complex, subunit 1 | 0.00526209 |
| TTN | titin | 0.00525836 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.00521193 |
| TYR | tyrosinase | 0.00518997 |
| SDCBP | syndecan binding protein (syntenin) | 0.00517675 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00517654 |
| CAPN6 | calpain 6 | 0.00517391 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00516337 |
| KLF1 | Kruppel-like factor 1 (erythroid) | 0.0051515 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00513517 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00512809 |
| TRAF1 | TNF receptor-associated factor 1 | 0.00512383 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0272356 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0172463 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.0172111 |
| BEX1 | brain expressed, X-linked 1 | -0.0168497 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0136625 |
| MGP | matrix Gla protein | -0.0129737 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0128744 |
| KRT19 | keratin 19, type I | -0.0126722 |
| OPHN1 | oligophrenin 1 | -0.0125851 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.0121573 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0120265 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.0119196 |
| PERP | PERP, TP53 apoptosis effector | -0.0117258 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0110859 |
| CTSZ | cathepsin Z | -0.0107694 |
| EMP1 | epithelial membrane protein 1 | -0.0106797 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0106574 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0106192 |
| APOD | apolipoprotein D | -0.0103374 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0102049 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0100528 |
| ASRGL1 | asparaginase like 1 | -0.0097903 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00954346 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00946383 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00914517 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00909957 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00900674 |
| HEBP2 | heme binding protein 2 | -0.00888378 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00879669 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.0087954 |
| CFH | complement factor H | -0.00863776 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00861335 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00854948 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00850154 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00838261 |
| DSP | desmoplakin | -0.00831851 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00830964 |
| TCTN2 | tectonic family member 2 | -0.00826946 |
| METTL7A | methyltransferase like 7A | -0.00825293 |
| CFI | complement factor I | -0.00824649 |
| KRT18 | keratin 18, type I | -0.00822043 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00821229 |
| GPX4 | glutathione peroxidase 4 | -0.00818938 |
| THBS2 | thrombospondin 2 | -0.00811505 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00803084 |
| REEP1 | receptor accessory protein 1 | -0.00795788 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0079396 |
| GLUL | glutamate-ammonia ligase | -0.00789151 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00779793 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00775519 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00775482 |
| ASPN | asporin | -0.0077244 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00765945 |
| PEG3 | paternally expressed 3 | -0.00765383 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00764823 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0076075 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00760192 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00756618 |
| AHNAK | AHNAK nucleoprotein | -0.00756326 |
| COLEC12 | collectin sub-family member 12 | -0.0074703 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00738491 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0073725 |
| ABHD3 | abhydrolase domain containing 3 | -0.00732883 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00728393 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00727471 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0072501 |
| NPTX2 | neuronal pentraxin II | -0.00722076 |
| ANXA1 | annexin A1 | -0.00720348 |
| EPCAM | epithelial cell adhesion molecule | -0.00719734 |
| OSTF1 | osteoclast stimulating factor 1 | -0.00718885 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00716047 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00713508 |
| BRD2 | bromodomain containing 2 | -0.0071173 |
| CD99 | CD99 molecule | -0.00711492 |
| NUTF2 | nuclear transport factor 2 | -0.00707726 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00706935 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00703242 |
| CFD | complement factor D (adipsin) | -0.00693176 |
| RBBP4 | retinoblastoma binding protein 4 | -0.00691593 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.00689889 |
| NRN1 | neuritin 1 | -0.00686302 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00684818 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00680033 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00675175 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00667917 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00667483 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00660918 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00658761 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00658631 |
| GSN | gelsolin | -0.00656295 |
| CES1 | carboxylesterase 1 | -0.00656281 |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | -0.00649368 |
| IPO13 | importin 13 | -0.00648815 |
| EFNA1 | ephrin-A1 | -0.00648395 |
| CP | ceruloplasmin (ferroxidase) | -0.00647338 |
| ELOVL2 | ELOVL fatty acid elongase 2 | -0.00640729 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00640246 |
| A2M | alpha-2-macroglobulin | -0.00639824 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -0.00639349 |
| TXNIP | thioredoxin interacting protein | -0.00639262 |
| SYT1 | synaptotagmin I | -0.00636143 |
| HOXC6 | homeobox C6 | -0.00636062 |
| TXN | thioredoxin | -0.00634024 |
| RPL14 | ribosomal protein L14 | -0.00630646 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00628776 |
| RNASET2 | ribonuclease T2 | -0.00628512 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00626475 |
| RGS10 | regulator of G-protein signaling 10 | -0.00623946 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00622997 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00622249 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00622186 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00621923 |
| DSTN | destrin (actin depolymerizing factor) | -0.0061964 |
| SHTN1 | shootin 1 | -0.00614394 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -0.00614171 |
| EIF6 | eukaryotic translation initiation factor 6 | -0.00607442 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00604416 |
| MYOF | myoferlin | -0.0060182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00599785 |
| TBCA | tubulin folding cofactor A | -0.00593408 |
| FKBP5 | FK506 binding protein 5 | -0.00593347 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00592261 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00585774 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00581705 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0057992 |
| MAPT | microtubule-associated protein tau | -0.00579812 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00579675 |
| S100A10 | S100 calcium binding protein A10 | -0.00579183 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00579004 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.0057806 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00577971 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | -0.00577776 |
| KRT8 | keratin 8, type II | -0.00577262 |
| MT1M | metallothionein 1M | -0.0057672 |
| AEBP1 | AE binding protein 1 | -0.00576129 |
| TSPO | translocator protein (18kDa) | -0.00575332 |
| PFDN5 | prefoldin subunit 5 | -0.005753 |
| MEN1 | multiple endocrine neoplasia I | -0.00575132 |
| SDC2 | syndecan 2 | -0.00574697 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00573185 |
| CCN2 | cellular communication network factor 2 | -0.00571611 |
| SPP1 | secreted phosphoprotein 1 | -0.00571273 |
| COMP | cartilage oligomeric matrix protein | -0.00569282 |
| INSR | insulin receptor | -0.00567444 |
| ADI1 | acireductone dioxygenase 1 | -0.00566666 |
| ATP5MG | ATP synthase membrane subunit g | -0.00565255 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00565076 |
| MAOA | monoamine oxidase A | -0.00564905 |
| THBS4 | thrombospondin 4 | -0.00564197 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.00563898 |
| YIPF5 | Yip1 domain family, member 5 | -0.00563676 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00560596 |
| MFAP5 | microfibrillar associated protein 5 | -0.00560436 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00560205 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.00559516 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.00558467 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00557947 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00557513 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.00557493 |
| AGPS | alkylglycerone phosphate synthase | -0.00556594 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00556444 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00556078 |
| FADS3 | fatty acid desaturase 3 | -0.00555043 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00553981 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00553806 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00551636 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | -0.0055115 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.00548153 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.00547789 |
| CERT1 | ceramide transporter 1 | -0.00546493 |
| PRNP | prion protein | -0.00545941 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0054465 |
| GNAS | GNAS complex locus | -0.00542772 |
| TANK | TRAF family member-associated NFKB activator | -0.00541233 |
| ALB | albumin | -0.00541215 |
| CLIC1 | chloride intracellular channel 1 | -0.00540356 |
| GPX3 | glutathione peroxidase 3 | -0.00538259 |
| DCN | decorin | -0.00535069 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | -0.0053436 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00533638 |
| ACYP2 | acylphosphatase 2, muscle type | -0.00533068 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00531301 |
| MXRA5 | matrix-remodelling associated 5 | -0.00530376 |
| IL1R1 | interleukin 1 receptor, type I | -0.00529849 |
| TPD52 | tumor protein D52 | -0.00528745 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00527452 |
| RGS5 | regulator of G-protein signaling 5 | -0.00527117 |
| NLGN4X | neuroligin 4, X-linked | -0.00526619 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00524652 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.00523943 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00522712 |
| MYO6 | myosin VI | -0.00522591 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00522459 |
| CCNG2 | cyclin G2 | -0.00519819 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00519355 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00519095 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00518746 |
| PRDX3 | peroxiredoxin 3 | -0.00518692 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.00518244 |
| MSX1 | msh homeobox 1 | -0.00515587 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.00515482 |
| WASHC3 | WASH complex subunit 3 | -0.00514244 |
| SEPTIN11 | septin 11 | -0.00513852 |
| ADIRF | adipogenesis regulatory factor | -0.00511908 |
| FDX1 | ferredoxin 1 | -0.0051162 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00511075 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.00510504 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00509452 |
| ZNF165 | zinc finger protein 165 | -0.00508501 |
| RPS8 | ribosomal protein S8 | -0.00508247 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00507666 |
| RNF14 | ring finger protein 14 | -0.00506334 |
| PLIN1 | perilipin 1 | -0.00505784 |
| TMEM259 | transmembrane protein 259 | -0.0050427 |
| GRK2 | G protein-coupled receptor kinase 2 | -0.00503011 |
| C21ORF91 | chromosome 21 open reading frame 91 | -0.00502012 |
| MYCBP | MYC binding protein | -0.00500546 |
| GLOD4 | glyoxalase domain containing 4 | -0.00500119 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.0049833 |
| SELENOF | selenoprotein F | -0.00498313 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00497806 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.0049779 |
| STMN2 | stathmin 2 | -0.0049761 |
| SFPQ | splicing factor proline/glutamine-rich | -0.00496535 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00496182 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.0049614 |
| APOC2 | apolipoprotein C-II | -0.0049601 |
| MT1E | metallothionein 1E | -0.00495094 |
| SLC35E3 | solute carrier family 35, member E3 | -0.00494564 |
| HSBP1 | heat shock factor binding protein 1 | -0.00494525 |
| S100B | S100 calcium binding protein B | -0.00494475 |
| RNF141 | ring finger protein 141 | -0.00493722 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | -0.00493672 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00492772 |
| MPHOSPH6 | M-phase phosphoprotein 6 | -0.00492483 |
| HK2 | hexokinase 2 | -0.00491559 |
| RPS25 | ribosomal protein S25 | -0.00490856 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00490555 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | -0.00489089 |
| CEL | carboxyl ester lipase | -0.0048892 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00488738 |
| MECOM | MDS1 and EVI1 complex locus | -0.00488513 |
| RWDD1 | RWD domain containing 1 | -0.0048813 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00487151 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.00486892 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | -0.00486589 |
| CALHM2 | calcium homeostasis modulator 2 | -0.00486185 |
| METTL5 | methyltransferase like 5 | -0.00485189 |
| MOB4 | MOB family member 4, phocein | -0.00483638 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00483468 |
