| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.197837 |
| YAP1 | Yes-associated protein 1 | 0.11479 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.103387 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0979198 |
| HMGA2 | high mobility group AT-hook 2 | 0.0829025 |
| RRM2 | ribonucleotide reductase M2 | 0.080581 |
| INTS6 | integrator complex subunit 6 | 0.0713614 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0711016 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0703046 |
| ANXA1 | annexin A1 | 0.0696296 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0691329 |
| NHSL1 | NHS-like 1 | 0.0599105 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0590679 |
| ZNF638 | zinc finger protein 638 | 0.0580604 |
| ADIPOR2 | adiponectin receptor 2 | 0.0571554 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.056329 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0557517 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0557179 |
| DST | dystonin | 0.0543371 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0541568 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0534359 |
| PCBP2 | poly(rC) binding protein 2 | 0.0529551 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0527187 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0521373 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0517931 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0505186 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0503373 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0498715 |
| WWOX | WW domain containing oxidoreductase | 0.0482838 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0474421 |
| TPI1 | triosephosphate isomerase 1 | 0.0454579 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0450872 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0446477 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0443196 |
| RBM39 | RNA binding motif protein 39 | 0.0438317 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0433019 |
| PRELID2 | PRELI domain containing 2 | 0.0432312 |
| PRKCE | protein kinase C, epsilon | 0.0430519 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0425676 |
| RNF213 | ring finger protein 213 | 0.0425154 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0418521 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0417858 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0414125 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0413012 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0401039 |
| BRD2 | bromodomain containing 2 | 0.0399831 |
| PEG10 | paternally expressed 10 | 0.039747 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0391505 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0388561 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.038661 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0383621 |
| PCDH9 | protocadherin 9 | 0.03811 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0381018 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0380139 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0373411 |
| LDHA | lactate dehydrogenase A | 0.0373023 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0370709 |
| POTEF | POTE ankyrin domain family, member F | 0.0368303 |
| ASPH | aspartate beta-hydroxylase | 0.0368297 |
| DENND5A | DENN/MADD domain containing 5A | 0.0366153 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0363517 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0363061 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0358206 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.035784 |
| SETD5 | SET domain containing 5 | 0.0355113 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0355037 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0350638 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0348682 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0344642 |
| SSH2 | slingshot protein phosphatase 2 | 0.0338609 |
| AFF4 | AF4/FMR2 family, member 4 | 0.033383 |
| XPO1 | exportin 1 | 0.0332187 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | 0.0328008 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0327817 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0326697 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0322159 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.031824 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0317618 |
| INTS4 | integrator complex subunit 4 | 0.0312983 |
| CTBP2 | C-terminal binding protein 2 | 0.0312578 |
| MED13L | mediator complex subunit 13-like | 0.03112 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0307313 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0307198 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0307117 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0306633 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0305311 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0300392 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0295758 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0293119 |
| PTK2 | protein tyrosine kinase 2 | 0.0292269 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0291988 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0289732 |
| STAG2 | stromal antigen 2 | 0.0288543 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0287583 |
| HELZ | helicase with zinc finger | 0.0286956 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0284983 |
| DIAPH3 | diaphanous-related formin 3 | 0.0284942 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0283989 |
| PAPOLA | poly(A) polymerase alpha | 0.0283432 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0282995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.155331 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.150264 |
| SLC38A2 | solute carrier family 38, member 2 | -0.088082 |
| AREG | amphiregulin | -0.0826319 |
| TMSB10 | thymosin beta 10 | -0.073086 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0668797 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0665745 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0659816 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0608262 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0486736 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0463407 |
| PCDH7 | protocadherin 7 | -0.0458672 |
| TMEM41B | transmembrane protein 41B | -0.0458636 |
| RPL11 | ribosomal protein L11 | -0.0438996 |
| CLDN1 | claudin 1 | -0.0427094 |
| RPL26 | ribosomal protein L26 | -0.0421642 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0415463 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0394343 |
| RPL37 | ribosomal protein L37 | -0.0376373 |
| BCHE | butyrylcholinesterase | -0.0368886 |
| RPS6 | ribosomal protein S6 | -0.0368551 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0368532 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.036255 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0358693 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0338123 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0334832 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.031584 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0313656 |
| RPS24 | ribosomal protein S24 | -0.0312713 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0307416 |
| KLF6 | Kruppel-like factor 6 | -0.0295096 |
| TXNRD1 | thioredoxin reductase 1 | -0.0293163 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.028292 |
| RPS27A | ribosomal protein S27a | -0.0282442 |
| NLN | neurolysin (metallopeptidase M3 family) | -0.027406 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0270114 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267641 |
| RPS13 | ribosomal protein S13 | -0.0267254 |
| RPL34 | ribosomal protein L34 | -0.0264376 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0263563 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0255394 |
| RASA2 | RAS p21 protein activator 2 | -0.0250354 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.024547 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0244198 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0241596 |
| SBF2 | SET binding factor 2 | -0.0240401 |
| MATR3 | matrin 3 | -0.0240296 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0234578 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.0232268 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0232053 |
| ZNF804A | zinc finger protein 804A | -0.0229996 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0229059 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0226859 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0226275 |
| PHF14 | PHD finger protein 14 | -0.0225968 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0225524 |
| RPLP0 | ribosomal protein, large, P0 | -0.0224667 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0223075 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0223062 |
| RASAL2 | RAS protein activator like 2 | -0.0217736 |
| RPLP2 | ribosomal protein, large, P2 | -0.0217494 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0211609 |
| RTN4 | reticulon 4 | -0.0211077 |
| ZFR | zinc finger RNA binding protein | -0.0209659 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0206327 |
| TUBB6 | tubulin, beta 6 class V | -0.0205526 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0203012 |
| RPL5 | ribosomal protein L5 | -0.0201001 |
| RPS5 | ribosomal protein S5 | -0.02007 |
| RPL12 | ribosomal protein L12 | -0.0200037 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0199004 |
| RPL9 | ribosomal protein L9 | -0.0198191 |
| RPL7A | ribosomal protein L7a | -0.0193191 |
| RAI14 | retinoic acid induced 14 | -0.0190118 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | -0.0189439 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0188606 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0187243 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0186033 |
| FOXK2 | forkhead box K2 | -0.0185711 |
| TSPAN5 | tetraspanin 5 | -0.0185495 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0184114 |
| CCN2 | cellular communication network factor 2 | -0.0183881 |
| RPS16 | ribosomal protein S16 | -0.0183026 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0182171 |
| RPS21 | ribosomal protein S21 | -0.0182061 |
| TCERG1 | transcription elongation regulator 1 | -0.0180956 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.018003 |
| RPL35A | ribosomal protein L35a | -0.0180028 |
| RPS2 | ribosomal protein S2 | -0.018001 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0179143 |
| RPS27 | ribosomal protein S27 | -0.0179045 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0178943 |
| EGR1 | early growth response 1 | -0.017556 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0174174 |
| ZDHHC2 | zinc finger, DHHC-type containing 2 | -0.017382 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0172062 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0170968 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0170602 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0170452 |
| NKTR | natural killer cell triggering receptor | -0.0169804 |
