| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.183956 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.115556 |
| SMAD3 | SMAD family member 3 | 0.102204 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.101473 |
| FNDC3B | fibronectin type III domain containing 3B | 0.101228 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.101138 |
| NAV2 | neuron navigator 2 | 0.0949721 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0838199 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0816535 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0782458 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0736342 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0716601 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0685184 |
| INTS6 | integrator complex subunit 6 | 0.0683816 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0676698 |
| JAK1 | Janus kinase 1 | 0.0644371 |
| NRP2 | neuropilin 2 | 0.0619625 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0613278 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0611307 |
| VCL | vinculin | 0.0560598 |
| KYNU | kynureninase | 0.0551122 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0518252 |
| TLE4 | transducin-like enhancer of split 4 | 0.0512109 |
| CTBP2 | C-terminal binding protein 2 | 0.0510315 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0509012 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0506837 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0492055 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0481036 |
| PAX8 | paired box 8 | 0.0468634 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0465004 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0460568 |
| MSN | moesin | 0.0434501 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0428399 |
| SPAG9 | sperm associated antigen 9 | 0.042759 |
| FMNL2 | formin-like 2 | 0.0408648 |
| SEPTIN9 | septin 9 | 0.0408417 |
| SUCO | SUN domain containing ossification factor | 0.0404638 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0403092 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0386469 |
| TUFT1 | tuftelin 1 | 0.038085 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0378222 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0374855 |
| PLEC | plectin | 0.037465 |
| CRY1 | cryptochrome circadian clock 1 | 0.0371406 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0370486 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0367582 |
| HDAC9 | histone deacetylase 9 | 0.0365322 |
| COPA | coatomer protein complex, subunit alpha | 0.0364723 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0360891 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0349951 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.034412 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0343846 |
| NUP98 | nucleoporin 98kDa | 0.0341504 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0340072 |
| UBAP2 | ubiquitin associated protein 2 | 0.0324988 |
| POTEF | POTE ankyrin domain family, member F | 0.0323291 |
| TGM2 | transglutaminase 2 | 0.0323159 |
| CD44 | CD44 molecule (Indian blood group) | 0.0320432 |
| MB21D2 | Mab-21 domain containing 2 | 0.0317422 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0313457 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0312873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0312526 |
| ACTN4 | actinin, alpha 4 | 0.0305745 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0298421 |
| RBM39 | RNA binding motif protein 39 | 0.0295627 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0293529 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.028961 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0288436 |
| MRTFA | myocardin related transcription factor A | 0.0287963 |
| MYOF | myoferlin | 0.0287475 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0286345 |
| TUT7 | terminal uridylyl transferase 7 | 0.0285812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.028532 |
| IFI44L | interferon-induced protein 44-like | 0.0281967 |
| CADM1 | cell adhesion molecule 1 | 0.028183 |
| ANXA5 | annexin A5 | 0.0281738 |
| DENND4A | DENN/MADD domain containing 4A | 0.0278917 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.027049 |
| MCL1 | myeloid cell leukemia 1 | 0.0266524 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0264721 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0259917 |
| SQSTM1 | sequestosome 1 | 0.0256343 |
| MSR1 | macrophage scavenger receptor 1 | 0.0255111 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.025204 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0251571 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.024843 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0247579 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0247066 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0244976 |
| NOCT | nocturnin | 0.0244174 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0243948 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0241359 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0241097 |
| CCNL1 | cyclin L1 | 0.0238597 |
| GPR176 | G protein-coupled receptor 176 | 0.0234855 |
| PGM3 | phosphoglucomutase 3 | 0.0234116 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0233803 |
| TJP1 | tight junction protein 1 | 0.0233077 |
| ZNF644 | zinc finger protein 644 | 0.0232514 |
| TFG | TRK-fused gene | 0.0232165 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.160651 |
| VIM | vimentin | -0.10944 |
| CP | ceruloplasmin (ferroxidase) | -0.102661 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101168 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0758405 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0671848 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0645665 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0632772 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0627504 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.060314 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0513989 |
| EHBP1 | EH domain binding protein 1 | -0.0481255 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0475461 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0469404 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0459412 |
| OXR1 | oxidation resistance 1 | -0.0443144 |
| PLIN2 | perilipin 2 | -0.0418829 |
| ANXA4 | annexin A4 | -0.0416668 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0409678 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0402243 |
| PTGR1 | prostaglandin reductase 1 | -0.0389675 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0389458 |
| CAVIN1 | caveolae associated protein 1 | -0.0388459 |
| PTMA | prothymosin, alpha | -0.0386457 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0384786 |
| MTDH | metadherin | -0.0384752 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0373675 |
| RAI14 | retinoic acid induced 14 | -0.0366505 |
| TPM4 | tropomyosin 4 | -0.0362899 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0359552 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0357471 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0343207 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0339923 |
| TPM1 | tropomyosin 1 (alpha) | -0.0331313 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0329025 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0327991 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.032361 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0322701 |
| S100A6 | S100 calcium binding protein A6 | -0.0314243 |
| CA12 | carbonic anhydrase XII | -0.0310596 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0309933 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0306486 |
| SP3 | Sp3 transcription factor | -0.0305418 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0303337 |
| PLK2 | polo-like kinase 2 | -0.029406 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0293995 |
| CALD1 | caldesmon 1 | -0.0293875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0291627 |
| HLA-B | major histocompatibility complex, class I, B | -0.0283235 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0282117 |
| FN1 | fibronectin 1 | -0.0278781 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0278764 |
| GLIS3 | GLIS family zinc finger 3 | -0.0275645 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0275569 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0275294 |
| STK17A | serine/threonine kinase 17a | -0.0275291 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0275019 |
| CALU | calumenin | -0.0274302 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0272329 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0271707 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0270486 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0270102 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0270068 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.026826 |
| B2M | beta-2-microglobulin | -0.0267951 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0267043 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0266232 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.026579 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0262952 |
| CDCP1 | CUB domain containing protein 1 | -0.0258784 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0257248 |
| THOC2 | THO complex 2 | -0.0256068 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0255974 |
| APOL1 | apolipoprotein L, 1 | -0.0254447 |
| TCF12 | transcription factor 12 | -0.0250159 |
| GPC6 | glypican 6 | -0.0250135 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0249127 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0247559 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0245375 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0244992 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0239922 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0238789 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0238385 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0237997 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0237193 |
| LAMB3 | laminin, beta 3 | -0.0237067 |
| CALR | calreticulin | -0.0236838 |
| UBXN4 | UBX domain protein 4 | -0.023435 |
| ACTG1 | actin gamma 1 | -0.0232506 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0230207 |
| SRP72 | signal recognition particle 72kDa | -0.0229265 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0228597 |
| MT2A | metallothionein 2A | -0.0225635 |
| SCFD2 | sec1 family domain containing 2 | -0.0224625 |
| PTH2R | parathyroid hormone 2 receptor | -0.0222335 |
| CDK13 | cyclin-dependent kinase 13 | -0.0221123 |
| SMYD3 | SET and MYND domain containing 3 | -0.022095 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0220195 |
| HLA-E | major histocompatibility complex, class I, E | -0.0219788 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0218908 |
