| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.109525 |
| MCL1 | myeloid cell leukemia 1 | 0.107117 |
| SMAD3 | SMAD family member 3 | 0.100139 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0986802 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0947487 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0870727 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.084938 |
| SPAG9 | sperm associated antigen 9 | 0.0798099 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0756912 |
| MSN | moesin | 0.0670936 |
| USP3 | ubiquitin specific peptidase 3 | 0.064515 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0640883 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0627949 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0624303 |
| FMNL2 | formin-like 2 | 0.062268 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0621622 |
| GRB10 | growth factor receptor-bound protein 10 | 0.060919 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0573664 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0569817 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0558295 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0551197 |
| CCNL1 | cyclin L1 | 0.0549787 |
| TNS1 | tensin 1 | 0.054874 |
| ASPH | aspartate beta-hydroxylase | 0.0536674 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0528024 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0520359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0520203 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0518895 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0516078 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0502353 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0489246 |
| HELZ | helicase with zinc finger | 0.047822 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0477845 |
| PCBP2 | poly(rC) binding protein 2 | 0.0472597 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0465446 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0461054 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0458621 |
| POTEF | POTE ankyrin domain family, member F | 0.0450006 |
| ECT2 | epithelial cell transforming 2 | 0.0447971 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0443985 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0437682 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0432273 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0430226 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0415121 |
| NUP58 | nucleoporin 58 | 0.0399336 |
| LMO7 | LIM domain 7 | 0.0393266 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.038823 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0386419 |
| FTL | ferritin, light polypeptide | 0.0385162 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0380977 |
| VCL | vinculin | 0.0369542 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0366321 |
| LDHA | lactate dehydrogenase A | 0.0354095 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.034986 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0349096 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0347147 |
| VMP1 | vacuole membrane protein 1 | 0.0344081 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0341783 |
| WAC | WW domain containing adaptor with coiled-coil | 0.034007 |
| BMP6 | bone morphogenetic protein 6 | 0.0339396 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0334796 |
| INTS6 | integrator complex subunit 6 | 0.0334619 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0333243 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0333019 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0332966 |
| CAPRIN2 | caprin family member 2 | 0.0330697 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0330205 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0322831 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0322227 |
| CTBP2 | C-terminal binding protein 2 | 0.0320044 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.031747 |
| AUTS2 | autism susceptibility candidate 2 | 0.0314326 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0312005 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0309915 |
| RNF145 | ring finger protein 145 | 0.0308683 |
| DSPP | dentin sialophosphoprotein | 0.0303356 |
| OGA | O-GlcNAcase | 0.0301722 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0300516 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0299675 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0299142 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298232 |
| FAT1 | FAT atypical cadherin 1 | 0.0294607 |
| AXL | AXL receptor tyrosine kinase | 0.0290169 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.028993 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0285272 |
| FLNB | filamin B, beta | 0.0285078 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0284227 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0278982 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0278074 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0277014 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0276391 |
| CORO1C | coronin, actin binding protein, 1C | 0.0275404 |
| ATXN1 | ataxin 1 | 0.0273493 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0271954 |
| VEGFA | vascular endothelial growth factor A | 0.0271643 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0270629 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0270393 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0269752 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0261279 |
| PLEC | plectin | 0.0259708 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.114352 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.1043 |
| OSMR | oncostatin M receptor | -0.0949598 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0924682 |
| ACTG1 | actin gamma 1 | -0.09177 |
| VIM | vimentin | -0.0905467 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0901487 |
| TMSB10 | thymosin beta 10 | -0.0868484 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0809742 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0757173 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0739993 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0736892 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0722006 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0719789 |
| KRT81 | keratin 81, type II | -0.0622424 |
| CA12 | carbonic anhydrase XII | -0.0595315 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0592723 |
| EHBP1 | EH domain binding protein 1 | -0.0578558 |
| RAI14 | retinoic acid induced 14 | -0.0544861 |
| RPS16 | ribosomal protein S16 | -0.0535342 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.053045 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0523449 |
| RRBP1 | ribosome binding protein 1 | -0.0522498 |
| S100A6 | S100 calcium binding protein A6 | -0.0514889 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0502915 |
| TXNRD1 | thioredoxin reductase 1 | -0.0502511 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0495177 |
| RIN2 | Ras and Rab interactor 2 | -0.0485515 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0484586 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0465214 |
| RPS24 | ribosomal protein S24 | -0.0453763 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.044231 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0424734 |
| SBF2 | SET binding factor 2 | -0.0415468 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0402884 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0382013 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0370096 |
| ATG7 | autophagy related 7 | -0.036729 |
| ANXA4 | annexin A4 | -0.0362626 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0352717 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0349579 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0345361 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0344167 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0342829 |
| NF1 | neurofibromin 1 | -0.0340435 |
| RPLP1 | ribosomal protein, large, P1 | -0.0338612 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0333617 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0329868 |
| BMERB1 | bMERB domain containing 1 | -0.0324085 |
| NRP1 | neuropilin 1 | -0.0323583 |
| GPRIN3 | GPRIN family member 3 | -0.032349 |
| TNS3 | tensin 3 | -0.03206 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.031906 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0316116 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0315172 |
| TCF12 | transcription factor 12 | -0.0314556 |
| GOLGB1 | golgin B1 | -0.0312656 |
| RIGI | RNA sensor RIG-I | -0.0311795 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0311628 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.031124 |
| CUX1 | cut-like homeobox 1 | -0.031116 |
| RPL26 | ribosomal protein L26 | -0.0308703 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0307042 |
| GLIS3 | GLIS family zinc finger 3 | -0.0306458 |
| PCED1B | PC-esterase domain containing 1B | -0.030408 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.029915 |
| KIAA1217 | KIAA1217 | -0.0298265 |
| GPATCH8 | G patch domain containing 8 | -0.0297854 |
| RPL12 | ribosomal protein L12 | -0.0296359 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.029528 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0290903 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0290241 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0282525 |
| MYO9A | myosin IXA | -0.0279873 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0276837 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0272158 |
| HLA-B | major histocompatibility complex, class I, B | -0.0267855 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0266809 |
| CP | ceruloplasmin (ferroxidase) | -0.0265834 |
| RNF213 | ring finger protein 213 | -0.0264526 |
| KIFC3 | kinesin family member C3 | -0.0257347 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0255391 |
| AOPEP | aminopeptidase O (putative) | -0.0252272 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0252197 |
| S100A10 | S100 calcium binding protein A10 | -0.0250384 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0248891 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0248253 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.024498 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0244601 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0242908 |
| MAP1B | microtubule-associated protein 1B | -0.0242401 |
| SP100 | SP100 nuclear antigen | -0.024166 |
| PDE10A | phosphodiesterase 10A | -0.024158 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0240164 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0238709 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0238469 |
| ZNF609 | zinc finger protein 609 | -0.0237759 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0236277 |
| HM13 | histocompatibility (minor) 13 | -0.0236106 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0235548 |
