| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEP250 | centrosomal protein 250kDa | 0.0871719 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0760501 |
| INTS6 | integrator complex subunit 6 | 0.0602299 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0601501 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0570938 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0547145 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0506704 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0503326 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0488433 |
| DTNA | dystrobrevin, alpha | 0.0475129 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.042783 |
| CLTC | clathrin, heavy chain (Hc) | 0.0412017 |
| VEGFA | vascular endothelial growth factor A | 0.0406851 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0402819 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0398166 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.038164 |
| CCNY | cyclin Y | 0.0373904 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0365436 |
| CDK12 | cyclin-dependent kinase 12 | 0.0360259 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0359242 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0353543 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0350207 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0332353 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.033213 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0326571 |
| FAM168A | family with sequence similarity 168, member A | 0.0325414 |
| VCP | valosin containing protein | 0.0320672 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0319762 |
| FAM219A | family with sequence similarity 219, member A | 0.031539 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0314453 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0310013 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0309387 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0306527 |
| NDRG1 | N-myc downstream regulated 1 | 0.0304867 |
| SMYD3 | SET and MYND domain containing 3 | 0.0302232 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0301275 |
| MSI2 | musashi RNA-binding protein 2 | 0.0296886 |
| LASP1 | LIM and SH3 protein 1 | 0.0294878 |
| PTK2 | protein tyrosine kinase 2 | 0.0294298 |
| YAP1 | Yes-associated protein 1 | 0.0291553 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0288351 |
| SBF2 | SET binding factor 2 | 0.0282828 |
| VMP1 | vacuole membrane protein 1 | 0.0282427 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0279066 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0273908 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0273717 |
| TPD52 | tumor protein D52 | 0.0272408 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0269243 |
| SP100 | SP100 nuclear antigen | 0.0263183 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0262394 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0261289 |
| RCOR1 | REST corepressor 1 | 0.0256717 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0256051 |
| KRT86 | keratin 86, type II | 0.0253594 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0251821 |
| PRELID2 | PRELI domain containing 2 | 0.0247865 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0247788 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0242722 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.0239534 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0239063 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0237326 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0236018 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.0234016 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0233826 |
| HELZ | helicase with zinc finger | 0.0233618 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0230662 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.022873 |
| MCL1 | myeloid cell leukemia 1 | 0.0224037 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223761 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0221616 |
| USO1 | USO1 vesicle transport factor | 0.0219949 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0219271 |
| NEBL | nebulette | 0.0218228 |
| DENND1A | DENN/MADD domain containing 1A | 0.021606 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0215261 |
| BBX | bobby sox homolog (Drosophila) | 0.0212808 |
| PLEC | plectin | 0.0210195 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0209065 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0208746 |
| MED13 | mediator complex subunit 13 | 0.0208559 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0208362 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.020688 |
| CDK13 | cyclin-dependent kinase 13 | 0.0206515 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0205711 |
| RAD51B | RAD51 paralog B | 0.0204384 |
| YEATS2 | YEATS domain containing 2 | 0.0204219 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0203388 |
| USP32 | ubiquitin specific peptidase 32 | 0.0200277 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0199249 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.019865 |
| RTN3 | reticulon 3 | 0.0198415 |
| TUFT1 | tuftelin 1 | 0.0197873 |
| PLSCR2 | phospholipid scramblase 2 | 0.0197827 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0196022 |
| DENND5A | DENN/MADD domain containing 5A | 0.0194401 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0193705 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0185218 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0184781 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0184271 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0183599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.251211 |
| RPL19 | ribosomal protein L19 | -0.205897 |
| PTMA | prothymosin, alpha | -0.0810881 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.073135 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0727278 |
| TMSB10 | thymosin beta 10 | -0.0718271 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0715218 |
| ASPH | aspartate beta-hydroxylase | -0.0618991 |
| MT2A | metallothionein 2A | -0.0601444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0556598 |
| RPL35A | ribosomal protein L35a | -0.053773 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0503445 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0495305 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0478711 |
| RPL12 | ribosomal protein L12 | -0.0470756 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0435289 |
| S100A9 | S100 calcium binding protein A9 | -0.0404405 |
| S100A8 | S100 calcium binding protein A8 | -0.0400568 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0398974 |
| RPS3 | ribosomal protein S3 | -0.0388832 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0387637 |
| RPS19 | ribosomal protein S19 | -0.038069 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0376406 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0371246 |
| NTN4 | netrin 4 | -0.0362346 |
| CCNI | cyclin I | -0.0359731 |
| OSMR | oncostatin M receptor | -0.0357983 |
| MYL12B | myosin, light chain 12B, regulatory | -0.035376 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0335506 |
| RPS8 | ribosomal protein S8 | -0.0333872 |
| RPS24 | ribosomal protein S24 | -0.0311513 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0311375 |
| RPS6 | ribosomal protein S6 | -0.0295358 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0292868 |
| B2M | beta-2-microglobulin | -0.0276744 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273031 |
| RPLP0 | ribosomal protein, large, P0 | -0.0271417 |
| S100A14 | S100 calcium binding protein A14 | -0.0270642 |
| RPLP1 | ribosomal protein, large, P1 | -0.0269141 |
| RPL34 | ribosomal protein L34 | -0.0268066 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0263935 |
| KLF6 | Kruppel-like factor 6 | -0.0261928 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0254867 |
| CCND1 | cyclin D1 | -0.0254254 |
| RPL8 | ribosomal protein L8 | -0.025419 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0251453 |
| FTL | ferritin, light polypeptide | -0.0250514 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0248965 |
| RPL35 | ribosomal protein L35 | -0.0248885 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0248254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0240679 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0240337 |
| RPS12 | ribosomal protein S12 | -0.023545 |
| AREG | amphiregulin | -0.0234888 |
| EGR1 | early growth response 1 | -0.0232018 |
| RPL26 | ribosomal protein L26 | -0.0231373 |
| GATA3 | GATA binding protein 3 | -0.0230689 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0229538 |
| RPS14 | ribosomal protein S14 | -0.0229177 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.022311 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0220661 |
| TMC5 | transmembrane channel-like 5 | -0.0218262 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0217877 |
| RPS27 | ribosomal protein S27 | -0.0217141 |
| S100A6 | S100 calcium binding protein A6 | -0.021659 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0216257 |
| MIEN1 | migration and invasion enhancer 1 | -0.0215391 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0214594 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0213793 |
| RPL9 | ribosomal protein L9 | -0.0212941 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0206038 |
| SMIM14 | small integral membrane protein 14 | -0.0205453 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0205265 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0204125 |
| PFDN4 | prefoldin subunit 4 | -0.0203658 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0203054 |
| RPL31 | ribosomal protein L31 | -0.0203033 |
| VIM | vimentin | -0.0202645 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0202093 |
| RPL32 | ribosomal protein L32 | -0.0199112 |
| RPL37 | ribosomal protein L37 | -0.0198767 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.019834 |
| RACK1 | receptor for activated C kinase 1 | -0.0198237 |
| RPS29 | ribosomal protein S29 | -0.0197784 |
| RPL30 | ribosomal protein L30 | -0.0196728 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0196434 |
| S100P | S100 calcium binding protein P | -0.0194909 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0194379 |
| RPL36 | ribosomal protein L36 | -0.0190534 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0189751 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0188917 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0188457 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0188244 |
| HMGB1 | high mobility group box 1 | -0.0187533 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0185957 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0185519 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0185118 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0183133 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0182705 |
| DSTN | destrin (actin depolymerizing factor) | -0.0181341 |
