| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.235566 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.107697 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0970197 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0594748 |
| DST | dystonin | 0.057278 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0549251 |
| VCL | vinculin | 0.0495861 |
| PRELID2 | PRELI domain containing 2 | 0.0491834 |
| CANX | calnexin | 0.0484993 |
| INTS6 | integrator complex subunit 6 | 0.0483927 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0479546 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0476192 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0447874 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0420579 |
| AHNAK | AHNAK nucleoprotein | 0.0417211 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0402707 |
| ATXN1 | ataxin 1 | 0.039091 |
| COL5A1 | collagen, type V, alpha 1 | 0.0378201 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0374333 |
| KYNU | kynureninase | 0.0373292 |
| RUNX1 | runt-related transcription factor 1 | 0.0368176 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0365597 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.034995 |
| SMAD3 | SMAD family member 3 | 0.0348332 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0348027 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0338543 |
| OGA | O-GlcNAcase | 0.0330961 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0322905 |
| MYOF | myoferlin | 0.0319839 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0308156 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0304649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303709 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0300775 |
| PLEC | plectin | 0.0298396 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0297132 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0295646 |
| ANO6 | anoctamin 6 | 0.0281614 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0275705 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0274619 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0267663 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.026259 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.026176 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0260806 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0259194 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0251382 |
| LOXL2 | lysyl oxidase-like 2 | 0.0247389 |
| HELZ | helicase with zinc finger | 0.0247365 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0243267 |
| EFNA5 | ephrin-A5 | 0.0241456 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0239523 |
| SMYD3 | SET and MYND domain containing 3 | 0.0237543 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0234971 |
| CADM1 | cell adhesion molecule 1 | 0.0233995 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0230951 |
| LOX | lysyl oxidase | 0.0224106 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0223989 |
| HDAC9 | histone deacetylase 9 | 0.0223723 |
| ZNF638 | zinc finger protein 638 | 0.0223099 |
| STK17A | serine/threonine kinase 17a | 0.021724 |
| FAM13A | family with sequence similarity 13, member A | 0.021558 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0215063 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0214354 |
| ACTN1 | actinin, alpha 1 | 0.0213742 |
| CLTC | clathrin, heavy chain (Hc) | 0.0212585 |
| TLN1 | talin 1 | 0.0209955 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0209476 |
| ANK2 | ankyrin 2, neuronal | 0.0209015 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0208836 |
| TLE4 | transducin-like enhancer of split 4 | 0.0208367 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0208255 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0206518 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0206143 |
| METTL15 | methyltransferase like 15 | 0.020573 |
| VEGFA | vascular endothelial growth factor A | 0.0204412 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204177 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0201984 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201941 |
| FNIP1 | folliculin interacting protein 1 | 0.0201532 |
| FTL | ferritin, light polypeptide | 0.0195846 |
| PHF21A | PHD finger protein 21A | 0.0195712 |
| EXOC6B | exocyst complex component 6B | 0.0193091 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0191564 |
| FLNB | filamin B, beta | 0.0191315 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0186319 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0185693 |
| BRD2 | bromodomain containing 2 | 0.0185441 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0184239 |
| PHF3 | PHD finger protein 3 | 0.0183937 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0183636 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0181978 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0181642 |
| HYOU1 | hypoxia up-regulated 1 | 0.0180051 |
| MSN | moesin | 0.0179041 |
| CALN1 | calneuron 1 | 0.0177379 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0176333 |
| EXOC4 | exocyst complex component 4 | 0.0173049 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0170934 |
| LDHA | lactate dehydrogenase A | 0.0169957 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0169862 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0169823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.211495 |
| TMSB10 | thymosin beta 10 | -0.177064 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.170265 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.132902 |
| MT2A | metallothionein 2A | -0.110686 |
| TPM4 | tropomyosin 4 | -0.0973984 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0939704 |
| PTMA | prothymosin, alpha | -0.0801728 |
| FN1 | fibronectin 1 | -0.0727043 |
| HLA-B | major histocompatibility complex, class I, B | -0.0720226 |
| HLA-A | major histocompatibility complex, class I, A | -0.0678249 |
| CALD1 | caldesmon 1 | -0.0652817 |
| B2M | beta-2-microglobulin | -0.0644387 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0642537 |
| NLGN1 | neuroligin 1 | -0.0618826 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0607757 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0573883 |
| IGF2 | insulin-like growth factor 2 | -0.0572903 |
| RPS6 | ribosomal protein S6 | -0.0549245 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0504448 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0492662 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0460512 |
| CLMP | CXADR-like membrane protein | -0.0457011 |
| S100A6 | S100 calcium binding protein A6 | -0.044564 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0439399 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0421031 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0420533 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.041637 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0407236 |
| POTEF | POTE ankyrin domain family, member F | -0.0386551 |
| PTK2 | protein tyrosine kinase 2 | -0.0380288 |
| RPL35A | ribosomal protein L35a | -0.0376579 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0365724 |
| ACTG1 | actin gamma 1 | -0.0352304 |
| RPS13 | ribosomal protein S13 | -0.0349643 |
| DTNA | dystrobrevin, alpha | -0.0342428 |
| GNAS | GNAS complex locus | -0.0339721 |
| ENO1 | enolase 1, (alpha) | -0.0329146 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0326414 |
| CD44 | CD44 molecule (Indian blood group) | -0.0321476 |
| CENPF | centromere protein F, 350/400kDa | -0.031543 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0309628 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0307702 |
| CD99 | CD99 molecule | -0.0300394 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0299728 |
| NAV1 | neuron navigator 1 | -0.0298958 |
| RPS8 | ribosomal protein S8 | -0.0298898 |
| CA9 | carbonic anhydrase IX | -0.0291883 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0289432 |
| STC1 | stanniocalcin 1 | -0.0287429 |
| S100A9 | S100 calcium binding protein A9 | -0.0284174 |
| TUBA1B | tubulin, alpha 1b | -0.0279331 |
| SEC61G | Sec61 gamma subunit | -0.0275442 |
| S100A10 | S100 calcium binding protein A10 | -0.0269283 |
| RPL37A | ribosomal protein L37a | -0.0264986 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0262555 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0262037 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0261574 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0261009 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0253151 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.025237 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0251059 |
| PFN1 | profilin 1 | -0.0250135 |
| PRSS23 | protease, serine, 23 | -0.0249987 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0245256 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0245188 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0243662 |
| MKI67 | marker of proliferation Ki-67 | -0.0242207 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0241765 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0240049 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0238549 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0237735 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.023548 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0233527 |
| RACK1 | receptor for activated C kinase 1 | -0.0232793 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0232106 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0232103 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0228443 |
| RPL34 | ribosomal protein L34 | -0.0228174 |
| RPL9 | ribosomal protein L9 | -0.0226305 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0220343 |
| TUBA1C | tubulin, alpha 1c | -0.0219618 |
| OXR1 | oxidation resistance 1 | -0.021775 |
| CD151 | CD151 molecule (Raph blood group) | -0.0214728 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0213234 |
| CTSD | cathepsin D | -0.021268 |
| CALU | calumenin | -0.0208906 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0207791 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.020758 |
| TPI1 | triosephosphate isomerase 1 | -0.0206344 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0205531 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0205462 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0201022 |
| HMGA1 | high mobility group AT-hook 1 | -0.0199679 |
| CCND1 | cyclin D1 | -0.0199576 |
| CBX3 | chromobox homolog 3 | -0.0199418 |
| CSTB | cystatin B (stefin B) | -0.0198876 |
| RPL7A | ribosomal protein L7a | -0.0197769 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0196857 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0196824 |
