| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0790459 |
| VEGFA | vascular endothelial growth factor A | 0.0568955 |
| LDHA | lactate dehydrogenase A | 0.0507454 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0452983 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0451034 |
| EZR | ezrin | 0.0449086 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.040286 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0402356 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0397507 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038487 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0370234 |
| TPM3 | tropomyosin 3 | 0.0368325 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.036135 |
| DSPP | dentin sialophosphoprotein | 0.0349644 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346585 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0337082 |
| SMAD3 | SMAD family member 3 | 0.0328536 |
| RPL3 | ribosomal protein L3 | 0.0314678 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0309765 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0305678 |
| BRD2 | bromodomain containing 2 | 0.0298468 |
| SDC4 | syndecan 4 | 0.0298006 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0295203 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0294064 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0294007 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0291054 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0288824 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0286344 |
| INTS6 | integrator complex subunit 6 | 0.0285744 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0283342 |
| PLEC | plectin | 0.0279296 |
| SFTPA2 | surfactant protein A2 | 0.0270508 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270004 |
| RUNX1 | runt-related transcription factor 1 | 0.0269601 |
| SETX | senataxin | 0.0269228 |
| ASPH | aspartate beta-hydroxylase | 0.0265533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0264897 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0263074 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0259908 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0259524 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0252337 |
| JUN | jun proto-oncogene | 0.0246813 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0246205 |
| HYOU1 | hypoxia up-regulated 1 | 0.0244142 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0243865 |
| RPL4 | ribosomal protein L4 | 0.0238054 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0236369 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0236326 |
| RPL21 | ribosomal protein L21 | 0.0232062 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0231915 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0230759 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0228796 |
| FN1 | fibronectin 1 | 0.0228157 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0226952 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0226736 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0216057 |
| POTEF | POTE ankyrin domain family, member F | 0.0213647 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0211365 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0206141 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0205398 |
| KAZN | kazrin, periplakin interacting protein | 0.0201719 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0201708 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0200985 |
| FAM117B | family with sequence similarity 117, member B | 0.0195765 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0194546 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.019375 |
| LMO7 | LIM domain 7 | 0.0192488 |
| NXF1 | nuclear RNA export factor 1 | 0.0191196 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0190542 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0190119 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.018984 |
| LAMC2 | laminin, gamma 2 | 0.0188844 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0188717 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0188574 |
| CCNL1 | cyclin L1 | 0.0188246 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0187619 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0187061 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0186079 |
| CCNG2 | cyclin G2 | 0.018544 |
| CLIC4 | chloride intracellular channel 4 | 0.0184457 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0181407 |
| TLN1 | talin 1 | 0.0181216 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0179939 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0178901 |
| VIM | vimentin | 0.0177875 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0177701 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0176565 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0175801 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0175628 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0175069 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0174054 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0173409 |
| COPA | coatomer protein complex, subunit alpha | 0.0172578 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.017156 |
| HOMER1 | homer scaffolding protein 1 | 0.0170525 |
| CALR | calreticulin | 0.0170093 |
| SCRN1 | secernin 1 | 0.016982 |
| CAPRIN2 | caprin family member 2 | 0.0169425 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0167933 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0167928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.185284 |
| FAT1 | FAT atypical cadherin 1 | -0.183727 |
| PTMA | prothymosin, alpha | -0.179682 |
| RAD51B | RAD51 paralog B | -0.127127 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.101332 |
| TMSB10 | thymosin beta 10 | -0.0979301 |
| FHIT | fragile histidine triad | -0.0886727 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0800803 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0796875 |
| SERINC5 | serine incorporator 5 | -0.0780654 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0780373 |
| TBC1D22A | TBC1 domain family, member 22A | -0.074912 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.074428 |
| WWOX | WW domain containing oxidoreductase | -0.0703997 |
| PARD3 | par-3 family cell polarity regulator | -0.0639842 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0627431 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0592942 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0588902 |
| NDRG1 | N-myc downstream regulated 1 | -0.0586775 |
| AHNAK | AHNAK nucleoprotein | -0.057449 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0567234 |
| SBF2 | SET binding factor 2 | -0.0563951 |
| SMYD3 | SET and MYND domain containing 3 | -0.0555466 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0538904 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0533233 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0530121 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0528694 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.051833 |
| MSI2 | musashi RNA-binding protein 2 | -0.0506002 |
| RPL35A | ribosomal protein L35a | -0.0483497 |
| ZNRF3 | zinc and ring finger 3 | -0.0481332 |
| DIAPH3 | diaphanous-related formin 3 | -0.0476906 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0465251 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0458548 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0452798 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0446122 |
| PRELID2 | PRELI domain containing 2 | -0.0438839 |
| CADPS | Ca++-dependent secretion activator | -0.0434804 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0432285 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0431954 |
| S100A10 | S100 calcium binding protein A10 | -0.0428204 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0425904 |
| DIAPH2 | diaphanous-related formin 2 | -0.0408355 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0407504 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0404506 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0400042 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0398105 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0397207 |
| ZFHX3 | zinc finger homeobox 3 | -0.0395736 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0394773 |
| RPLP0 | ribosomal protein, large, P0 | -0.0393142 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0386136 |
| RPL11 | ribosomal protein L11 | -0.0385183 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0381876 |
| DENND1A | DENN/MADD domain containing 1A | -0.0379524 |
| ACTG1 | actin gamma 1 | -0.0378823 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.037598 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0372618 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0371133 |
| RPS24 | ribosomal protein S24 | -0.0367912 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.036784 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0363711 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0353846 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0352286 |
| AK1 | adenylate kinase 1 | -0.034948 |
| RNF43 | ring finger protein 43 | -0.0348031 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0347512 |
| EPCAM | epithelial cell adhesion molecule | -0.0347074 |
| HMGB2 | high mobility group box 2 | -0.034345 |
| CLTC | clathrin, heavy chain (Hc) | -0.0342438 |
| HMGA2 | high mobility group AT-hook 2 | -0.0340702 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0336654 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0334068 |
| S100A9 | S100 calcium binding protein A9 | -0.0332298 |
| FRMD5 | FERM domain containing 5 | -0.0330437 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325622 |
| MT2A | metallothionein 2A | -0.0322587 |
| RPS27A | ribosomal protein S27a | -0.0320992 |
| EXOC4 | exocyst complex component 4 | -0.0317724 |
| TBC1D4 | TBC1 domain family, member 4 | -0.0316826 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.031556 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.0315501 |
| PHIP | pleckstrin homology domain interacting protein | -0.0314399 |
| SUMF1 | sulfatase modifying factor 1 | -0.0313872 |
| MEF2A | myocyte enhancer factor 2A | -0.030952 |
| PDE8A | phosphodiesterase 8A | -0.0301432 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300568 |
| KRT19 | keratin 19, type I | -0.0299923 |
| MED13L | mediator complex subunit 13-like | -0.0299449 |
| NOP58 | NOP58 ribonucleoprotein | -0.029831 |
| HOXB3 | homeobox B3 | -0.0297337 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.029659 |
| CEP128 | centrosomal protein 128kDa | -0.029401 |
| CUX1 | cut-like homeobox 1 | -0.0293146 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0292912 |
| TUBB | tubulin, beta class I | -0.0288405 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0287575 |
| NF1 | neurofibromin 1 | -0.0287379 |
| FDPS | farnesyl diphosphate synthase | -0.0286814 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0286068 |
