| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.13403 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.129671 |
| COL5A1 | collagen, type V, alpha 1 | 0.115387 |
| COL6A3 | collagen, type VI, alpha 3 | 0.108722 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0936585 |
| ENO1 | enolase 1, (alpha) | 0.0894989 |
| PLEC | plectin | 0.0885999 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0852356 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0811779 |
| NAV1 | neuron navigator 1 | 0.0784969 |
| RRM2 | ribonucleotide reductase M2 | 0.0730989 |
| AHNAK | AHNAK nucleoprotein | 0.0663104 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.065573 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.063058 |
| ASPH | aspartate beta-hydroxylase | 0.0585149 |
| NAV2 | neuron navigator 2 | 0.0566823 |
| LDHA | lactate dehydrogenase A | 0.0557795 |
| TNS1 | tensin 1 | 0.0553666 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0550169 |
| DTNA | dystrobrevin, alpha | 0.053848 |
| DST | dystonin | 0.0496122 |
| MYO10 | myosin X | 0.0484687 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0483242 |
| PRELID2 | PRELI domain containing 2 | 0.0482836 |
| LAMB3 | laminin, beta 3 | 0.0479974 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.047835 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.046566 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0464478 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0450278 |
| COL7A1 | collagen, type VII, alpha 1 | 0.043702 |
| RUNX1 | runt-related transcription factor 1 | 0.0435656 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0433537 |
| DIAPH2 | diaphanous-related formin 2 | 0.0423416 |
| ANXA2 | annexin A2 | 0.0421769 |
| WWOX | WW domain containing oxidoreductase | 0.0420616 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0407852 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0405683 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0401146 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0379692 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0376639 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0374456 |
| RAD51B | RAD51 paralog B | 0.0371956 |
| VEGFA | vascular endothelial growth factor A | 0.0367241 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0362024 |
| FAM13A | family with sequence similarity 13, member A | 0.0361481 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0349725 |
| MSN | moesin | 0.034309 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0330966 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0324181 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0322249 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0321648 |
| ATXN1 | ataxin 1 | 0.0317751 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0311117 |
| MAP1B | microtubule-associated protein 1B | 0.0308072 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0305952 |
| TPM3 | tropomyosin 3 | 0.0305049 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0301356 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300857 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0300475 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.029869 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0284514 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0284393 |
| RPL12 | ribosomal protein L12 | 0.0282844 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0279063 |
| AXL | AXL receptor tyrosine kinase | 0.0271986 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0271752 |
| FRMD4A | FERM domain containing 4A | 0.0270572 |
| EGFR | epidermal growth factor receptor | 0.0270522 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0265649 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0264612 |
| RPS6 | ribosomal protein S6 | 0.0263992 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0262796 |
| CFAP20DC | CFAP20 domain containing | 0.0255314 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0252321 |
| MMP12 | matrix metallopeptidase 12 | 0.0249711 |
| PTK2 | protein tyrosine kinase 2 | 0.0249139 |
| SEPTIN9 | septin 9 | 0.0247427 |
| CAPRIN2 | caprin family member 2 | 0.0247382 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0246963 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0242059 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0240368 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0239057 |
| ACTN1 | actinin, alpha 1 | 0.0233116 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0232385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230132 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0229482 |
| RPS4X | ribosomal protein S4, X-linked | 0.0227584 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0225068 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0223592 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0218063 |
| PGK1 | phosphoglycerate kinase 1 | 0.0217216 |
| EMP1 | epithelial membrane protein 1 | 0.0217029 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0215161 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0214815 |
| YBX1 | Y box binding protein 1 | 0.0212964 |
| FLNA | filamin A, alpha | 0.0212089 |
| FMNL2 | formin-like 2 | 0.0204327 |
| CEP192 | centrosomal protein 192kDa | 0.0203792 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0202082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.333577 |
| VIM | vimentin | -0.193516 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0980906 |
| IGF2 | insulin-like growth factor 2 | -0.0942435 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0805945 |
| TMSB10 | thymosin beta 10 | -0.0757672 |
| FN1 | fibronectin 1 | -0.0690821 |
| INHBA | inhibin, beta A | -0.0649867 |
| HMGA2 | high mobility group AT-hook 2 | -0.0644196 |
| EGR1 | early growth response 1 | -0.0627327 |
| PTMA | prothymosin, alpha | -0.0573302 |
| TENM2 | teneurin transmembrane protein 2 | -0.0552086 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0514147 |
| RTN4 | reticulon 4 | -0.0455495 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.040529 |
| IL1B | interleukin 1, beta | -0.0399714 |
| ACTG1 | actin gamma 1 | -0.0393244 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0374462 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0373827 |
| TXNIP | thioredoxin interacting protein | -0.0373388 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0371409 |
| COL1A1 | collagen, type I, alpha 1 | -0.0358754 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0351673 |
| OSMR | oncostatin M receptor | -0.0349391 |
| SETD5 | SET domain containing 5 | -0.0316647 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0315407 |
| CLMP | CXADR-like membrane protein | -0.0312235 |
| MT2A | metallothionein 2A | -0.0310726 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0300639 |
| SBF2 | SET binding factor 2 | -0.0297186 |
| SYAP1 | synapse associated protein 1 | -0.0295103 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0290701 |
| PDE10A | phosphodiesterase 10A | -0.0290553 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0285601 |
| STC1 | stanniocalcin 1 | -0.0283896 |
| TMEM165 | transmembrane protein 165 | -0.0279694 |
| CD44 | CD44 molecule (Indian blood group) | -0.0278042 |
| GLIS3 | GLIS family zinc finger 3 | -0.0272069 |
| LOX | lysyl oxidase | -0.0268655 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0263204 |
| CDCP1 | CUB domain containing protein 1 | -0.0262253 |
| WASF2 | WAS protein family, member 2 | -0.0254078 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0252341 |
| CCND1 | cyclin D1 | -0.0251893 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0242172 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0241645 |
| BPTF | bromodomain PHD finger transcription factor | -0.0238588 |
| NF1 | neurofibromin 1 | -0.0234992 |
| S100A6 | S100 calcium binding protein A6 | -0.0234184 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0228907 |
| S100A10 | S100 calcium binding protein A10 | -0.0228736 |
| USP34 | ubiquitin specific peptidase 34 | -0.0225284 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0222293 |
| CUX1 | cut-like homeobox 1 | -0.0221306 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0220699 |
| GLG1 | golgi glycoprotein 1 | -0.0219817 |
| MT1X | metallothionein 1X | -0.0219516 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0216165 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0213578 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0211711 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0208796 |
| HIP1 | huntingtin interacting protein 1 | -0.0208189 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0206949 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0206643 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0206523 |
| FAM193A | family with sequence similarity 193, member A | -0.0202263 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0202261 |
| TAGLN2 | transgelin 2 | -0.0201308 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0200216 |
| RNF24 | ring finger protein 24 | -0.0198581 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0197404 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0195545 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0194619 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0189317 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0188607 |
| PCNX4 | pecanex 4 | -0.0188469 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0185329 |
| RPL32 | ribosomal protein L32 | -0.0183084 |
| CD109 | CD109 molecule | -0.0180454 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.01803 |
| TUBB6 | tubulin, beta 6 class V | -0.0178977 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0178425 |
| PCNX1 | pecanex 1 | -0.0176603 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0174941 |
| TMEM263 | transmembrane protein 263 | -0.0172638 |
| RAI14 | retinoic acid induced 14 | -0.0170782 |
| SPAG9 | sperm associated antigen 9 | -0.0169794 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0167701 |
| ZNF609 | zinc finger protein 609 | -0.0167429 |
| GRAMD1B | GRAM domain containing 1B | -0.0167212 |
| TNNC1 | troponin C type 1 (slow) | -0.0167028 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0163332 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0161703 |
| MRC2 | mannose receptor, C type 2 | -0.0159928 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0158409 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0157295 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0156087 |
| WDR45B | WD repeat domain 45B | -0.015565 |
| CCNI | cyclin I | -0.015541 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0154335 |
