| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.160514 |
| FN1 | fibronectin 1 | 0.13127 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.107345 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0997761 |
| DSPP | dentin sialophosphoprotein | 0.0968495 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0916514 |
| FAM107B | family with sequence similarity 107, member B | 0.0886694 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0809826 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0787007 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0756668 |
| C3 | complement component 3 | 0.0734441 |
| TNS1 | tensin 1 | 0.0734279 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0734031 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0640092 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0633406 |
| INTS6 | integrator complex subunit 6 | 0.0628747 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0603908 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0588671 |
| TF | transferrin | 0.057811 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0549993 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.054369 |
| VEGFA | vascular endothelial growth factor A | 0.0532912 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0530209 |
| SDC4 | syndecan 4 | 0.0529971 |
| SVIL | supervillin | 0.0498952 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0444515 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0442956 |
| PEG3 | paternally expressed 3 | 0.0441031 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0423279 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0403708 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0391137 |
| MYO1E | myosin IE | 0.0388028 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0384315 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0368634 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0363742 |
| FAT1 | FAT atypical cadherin 1 | 0.036219 |
| SMAD3 | SMAD family member 3 | 0.0360894 |
| TCIM | transcriptional and immune response regulator | 0.0358151 |
| SEPTIN9 | septin 9 | 0.035274 |
| ATXN1 | ataxin 1 | 0.0351777 |
| GK | glycerol kinase | 0.0346423 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0346185 |
| TNS3 | tensin 3 | 0.0345835 |
| RAD51B | RAD51 paralog B | 0.0341962 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.033959 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0338705 |
| TMEM181 | transmembrane protein 181 | 0.0333583 |
| CCNY | cyclin Y | 0.0333168 |
| VMP1 | vacuole membrane protein 1 | 0.033066 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0330095 |
| ATF3 | activating transcription factor 3 | 0.0327914 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0327292 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0322833 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0318761 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0317932 |
| A2M | alpha-2-macroglobulin | 0.0317917 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.031102 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0309449 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0301607 |
| MCL1 | myeloid cell leukemia 1 | 0.0295345 |
| TBCK | TBC1 domain containing kinase | 0.02945 |
| PLEC | plectin | 0.0294046 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0289704 |
| ZNF638 | zinc finger protein 638 | 0.028946 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0288322 |
| SERTAD2 | SERTA domain containing 2 | 0.0287717 |
| CLIC4 | chloride intracellular channel 4 | 0.0283431 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0280924 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0279601 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0273887 |
| APOB | apolipoprotein B | 0.0271662 |
| PHF3 | PHD finger protein 3 | 0.0270605 |
| BRD4 | bromodomain containing 4 | 0.0268827 |
| FOXP1 | forkhead box P1 | 0.0268452 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0264412 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0263725 |
| CRY1 | cryptochrome circadian clock 1 | 0.0259473 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0253933 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0252715 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0252036 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0249586 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241623 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0240475 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0238496 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0238325 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0237532 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0236669 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.023641 |
| TUFT1 | tuftelin 1 | 0.0232999 |
| HDAC4 | histone deacetylase 4 | 0.0228959 |
| STK17A | serine/threonine kinase 17a | 0.0228938 |
| SDC2 | syndecan 2 | 0.0227809 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0226671 |
| CANX | calnexin | 0.022516 |
| DUSP6 | dual specificity phosphatase 6 | 0.0224432 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0223367 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0222031 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0221904 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0219116 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0217793 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.160197 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.136751 |
| IGF2 | insulin-like growth factor 2 | -0.0942188 |
| MT2A | metallothionein 2A | -0.0923146 |
| RPS6 | ribosomal protein S6 | -0.0881207 |
| FNDC3B | fibronectin type III domain containing 3B | -0.085369 |
| APOA2 | apolipoprotein A-II | -0.0805717 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0783694 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0713498 |
| TMSB10 | thymosin beta 10 | -0.0704693 |
| RPS24 | ribosomal protein S24 | -0.0604993 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0604658 |
| RPL37A | ribosomal protein L37a | -0.056517 |
| RPL35A | ribosomal protein L35a | -0.0548118 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0500812 |
| HMGA1 | high mobility group AT-hook 1 | -0.0495376 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0475811 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0473511 |
| RPLP0 | ribosomal protein, large, P0 | -0.0456942 |
| RPS8 | ribosomal protein S8 | -0.0446835 |
| RPL9 | ribosomal protein L9 | -0.0443647 |
| PLIN2 | perilipin 2 | -0.0437052 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0436918 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0435762 |
| RPLP1 | ribosomal protein, large, P1 | -0.0434346 |
| RPLP2 | ribosomal protein, large, P2 | -0.0415317 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.040346 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0396555 |
| PERP | PERP, TP53 apoptosis effector | -0.0389896 |
| OSMR | oncostatin M receptor | -0.038786 |
| FRMD5 | FERM domain containing 5 | -0.0385435 |
| ENO1 | enolase 1, (alpha) | -0.0377084 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0373801 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0373241 |
| RPL34 | ribosomal protein L34 | -0.0370811 |
| RPS12 | ribosomal protein S12 | -0.036432 |
| S100A9 | S100 calcium binding protein A9 | -0.036136 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0352747 |
| FTL | ferritin, light polypeptide | -0.0343859 |
| RPS29 | ribosomal protein S29 | -0.0338816 |
| RPS27A | ribosomal protein S27a | -0.0325799 |
| RBM25 | RNA binding motif protein 25 | -0.03245 |
| GDF15 | growth differentiation factor 15 | -0.0316523 |
| RPS21 | ribosomal protein S21 | -0.0307364 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0303407 |
| RTN4 | reticulon 4 | -0.0298119 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0297198 |
| RPL36 | ribosomal protein L36 | -0.0296405 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0288655 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.028792 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0287789 |
| RPS19 | ribosomal protein S19 | -0.0284681 |
| TPM4 | tropomyosin 4 | -0.028384 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0280968 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0277952 |
| PTMA | prothymosin, alpha | -0.0274379 |
| RPL12 | ribosomal protein L12 | -0.0272563 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0272049 |
| RPS14 | ribosomal protein S14 | -0.0264131 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0262343 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0262278 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0257089 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0252532 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0250105 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0247227 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0246943 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0245509 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0245396 |
| MRTFA | myocardin related transcription factor A | -0.0242333 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0241769 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0240644 |
| RPL31 | ribosomal protein L31 | -0.0240004 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0239245 |
| LYZ | lysozyme | -0.023872 |
| FERMT1 | fermitin family member 1 | -0.0238694 |
| RPL26 | ribosomal protein L26 | -0.0237489 |
| TCERG1 | transcription elongation regulator 1 | -0.0237249 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0236477 |
| CRLS1 | cardiolipin synthase 1 | -0.023539 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0233967 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0232568 |
| APOC1 | apolipoprotein C-I | -0.0232213 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0230757 |
| RPL36A | ribosomal protein L36a | -0.022815 |
| EGR1 | early growth response 1 | -0.022679 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0224911 |
| RPL23 | ribosomal protein L23 | -0.022412 |
| WDR45B | WD repeat domain 45B | -0.0222065 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0220557 |
| RPS10 | ribosomal protein S10 | -0.0219901 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0219525 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.021713 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0216152 |
| S100A6 | S100 calcium binding protein A6 | -0.021085 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.021052 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.0210243 |
| RPL37 | ribosomal protein L37 | -0.0209568 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0208206 |
| NUP58 | nucleoporin 58 | -0.0208128 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0208075 |
