Salicylic acid_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Salicylic acid perturbation in Hs 766T cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Salicylic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.141042
PALM2AKAP2 PALM2 and AKAP2 fusion 0.118624
MYH9 myosin, heavy chain 9, non-muscle 0.106773
PDLIM5 PDZ and LIM domain 5 0.100127
SMAD3 SMAD family member 3 0.0889131
PLEC plectin 0.0881572
TRIO trio Rho guanine nucleotide exchange factor 0.0787684
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.072832
PICALM phosphatidylinositol binding clathrin assembly protein 0.0701501
DOCK5 dedicator of cytokinesis 5 0.0680705
MBNL1 muscleblind-like splicing regulator 1 0.0680575
MSN moesin 0.0678695
AKAP13 A kinase (PRKA) anchor protein 13 0.0648582
MYOF myoferlin 0.064673
MACF1 microtubule-actin crosslinking factor 1 0.0617334
VCL vinculin 0.0606594
BCAR3 breast cancer anti-estrogen resistance 3 0.059956
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0545566
INTS6 integrator complex subunit 6 0.0530715
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.051231
RASAL2 RAS protein activator like 2 0.0495813
CAPRIN2 caprin family member 2 0.0495329
PRELID2 PRELI domain containing 2 0.0487499
DST dystonin 0.0477378
AMOTL1 angiomotin like 1 0.0474617
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0450718
ASPH aspartate beta-hydroxylase 0.0434563
FNDC3B fibronectin type III domain containing 3B 0.0416883
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0412199
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0411645
FOXO1 forkhead box O1 0.0405908
ANKRD28 ankyrin repeat domain 28 0.0401538
PLXNA2 plexin A2 0.0385754
ACTN1 actinin, alpha 1 0.0370472
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0368933
DPYD dihydropyrimidine dehydrogenase 0.0366957
LNPEP leucyl/cystinyl aminopeptidase 0.0357644
NEK7 NIMA-related kinase 7 0.0352323
ACTN4 actinin, alpha 4 0.0351705
DSCAM Down syndrome cell adhesion molecule 0.0345524
SIK3 SIK family kinase 3 0.0339011
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0332755
POTEF POTE ankyrin domain family, member F 0.0332075
PLS3 plastin 3 0.0327069
SLC35F3 solute carrier family 35, member F3 0.0319925
LAMA5 laminin, alpha 5 0.0317624
CD44 CD44 molecule (Indian blood group) 0.0317322
KIAA0040 KIAA0040 0.0315878
SLTM SAFB-like, transcription modulator 0.0302572
FLNB filamin B, beta 0.0299828
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0299296
ITGA6 integrin, alpha 6 0.0297786
ANO6 anoctamin 6 0.029778
FRMD6 FERM domain containing 6 0.0292932
BCL2L1 BCL2-like 1 0.0291822
ITPRID2 ITPR interacting domain containing 2 0.0290436
EGFR epidermal growth factor receptor 0.0281026
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0280602
GLS2 glutaminase 2 (liver, mitochondrial) 0.0278694
NCOR2 nuclear receptor corepressor 2 0.0276204
DIAPH1 diaphanous-related formin 1 0.0275241
TSC22D1 TSC22 domain family, member 1 0.0274006
ARHGAP29 Rho GTPase activating protein 29 0.0273166
AOPEP aminopeptidase O (putative) 0.0273046
HMGA2 high mobility group AT-hook 2 0.0266523
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0264581
CSMD2 CUB and Sushi multiple domains 2 0.0264399
SH3PXD2A SH3 and PX domains 2A 0.0263367
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like 0.0262587
DOCK4 dedicator of cytokinesis 4 0.0262026
ATXN1 ataxin 1 0.0261406
TJP1 tight junction protein 1 0.0260459
MCL1 myeloid cell leukemia 1 0.0260387
KIAA1671 KIAA1671 0.0260333
MBNL2 muscleblind-like splicing regulator 2 0.0259113
RCOR1 REST corepressor 1 0.0254457
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.0252254
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0250775
PTK2 protein tyrosine kinase 2 0.0247143
ZSWIM6 zinc finger, SWIM-type containing 6 0.0244469
JAG1 jagged 1 0.0241853
KLF12 Kruppel-like factor 12 0.0241599
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0233793
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0232326
CTBP2 C-terminal binding protein 2 0.0232006
MYO10 myosin X 0.023114
TBC1D5 TBC1 domain family, member 5 0.0230899
LUZP1 leucine zipper protein 1 0.0230757
SOX13 SRY (sex determining region Y)-box 13 0.0230346
RNF217 ring finger protein 217 0.0229611
SHB Src homology 2 domain containing adaptor protein B 0.0227132
VMP1 vacuole membrane protein 1 0.0226914
GPR176 G protein-coupled receptor 176 0.0224174
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0220424
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0220408
DOCK9 dedicator of cytokinesis 9 0.0219602
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 0.0218174
SAMD4A sterile alpha motif domain containing 4A 0.0217973
MPRIP myosin phosphatase Rho interacting protein 0.0217422
AFAP1L2 actin filament associated protein 1-like 2 0.0217322

decreased expression

Symbol Name Standardized Value
TIMP3 TIMP metallopeptidase inhibitor 3 -0.284144
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.148953
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.139204
TPT1 tumor protein, translationally-controlled 1 -0.133054
NDRG1 N-myc downstream regulated 1 -0.132585
STC1 stanniocalcin 1 -0.114879
B2M beta-2-microglobulin -0.107789
RPS8 ribosomal protein S8 -0.0990494
PTMA prothymosin, alpha -0.098438
MT2A metallothionein 2A -0.0929172
MTSS1 metastasis suppressor 1 -0.0831901
RPS6 ribosomal protein S6 -0.078022
RPS21 ribosomal protein S21 -0.0742818
ENO1 enolase 1, (alpha) -0.0727028
HLA-B major histocompatibility complex, class I, B -0.0710851
HLA-E major histocompatibility complex, class I, E -0.0685812
TMSB10 thymosin beta 10 -0.0665957
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0657625
RPS13 ribosomal protein S13 -0.0610169
PGK1 phosphoglycerate kinase 1 -0.0605351
S100A10 S100 calcium binding protein A10 -0.0601239
TMSB4X thymosin beta 4, X-linked -0.0599473
RPL34 ribosomal protein L34 -0.0597014
RPL37 ribosomal protein L37 -0.0594807
CLU clusterin -0.0581682
IFITM3 interferon induced transmembrane protein 3 -0.0574216
GNAS GNAS complex locus -0.0571357
ZMYND8 zinc finger, MYND-type containing 8 -0.0569027
RPLP2 ribosomal protein, large, P2 -0.0567028
RPL35A ribosomal protein L35a -0.056155
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0552357
RPS25 ribosomal protein S25 -0.0551042
ABI3BP ABI family, member 3 (NESH) binding protein -0.0540495
NAMPT nicotinamide phosphoribosyltransferase -0.0534848
RPS3 ribosomal protein S3 -0.051926
RPL11 ribosomal protein L11 -0.051353
FTL ferritin, light polypeptide -0.0512333
RPL12 ribosomal protein L12 -0.0496741
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0492977
RPLP1 ribosomal protein, large, P1 -0.0491139
EIF1 eukaryotic translation initiation factor 1 -0.0484367
IFITM1 interferon induced transmembrane protein 1 -0.0478181
RPL37A ribosomal protein L37a -0.0470021
RPS19 ribosomal protein S19 -0.0468815
RPL31 ribosomal protein L31 -0.0463944
RPS24 ribosomal protein S24 -0.0458257
RPL26 ribosomal protein L26 -0.0453981
RAI14 retinoic acid induced 14 -0.0447426
RPS12 ribosomal protein S12 -0.0438011
RPLP0 ribosomal protein, large, P0 -0.0430932
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0426801
FTH1 ferritin, heavy polypeptide 1 -0.042669
S100A6 S100 calcium binding protein A6 -0.0410652
S100A9 S100 calcium binding protein A9 -0.0395062
GOLGA4 golgin A4 -0.0376744
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0376315
MEF2A myocyte enhancer factor 2A -0.0375146
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0374081
RPL27A ribosomal protein L27a -0.0373599
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0359898
SQLE squalene epoxidase -0.0359737
RPL36 ribosomal protein L36 -0.0358863
RPL19 ribosomal protein L19 -0.0357399
PRRC2C proline-rich coiled-coil 2C -0.0357308
RPL36A ribosomal protein L36a -0.0354916
KIAA1217 KIAA1217 -0.0349712
RPL5 ribosomal protein L5 -0.034688
RPL8 ribosomal protein L8 -0.0343708
RPS27A ribosomal protein S27a -0.0341157
RPL30 ribosomal protein L30 -0.0340588
CSTB cystatin B (stefin B) -0.0338387
RACK1 receptor for activated C kinase 1 -0.0332838
LMNA lamin A/C -0.0327563
RPL23 ribosomal protein L23 -0.0326695
MT1E metallothionein 1E -0.0324329
CAVIN1 caveolae associated protein 1 -0.0320679
THBD thrombomodulin -0.032008
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0318488
IGF2 insulin-like growth factor 2 -0.0310949
RPS14 ribosomal protein S14 -0.0307741
SQSTM1 sequestosome 1 -0.0307395
RPS29 ribosomal protein S29 -0.030633
RPL7A ribosomal protein L7a -0.0305513
S100A11 S100 calcium binding protein A11 -0.0304399
HM13 histocompatibility (minor) 13 -0.0303991
H1-0 H1.0 linker histone -0.0303939
RPS23 ribosomal protein S23 -0.0301982
RPS27 ribosomal protein S27 -0.0301339
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0300373
RPS20 ribosomal protein S20 -0.0299099
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.0298503
RPL35 ribosomal protein L35 -0.0297189
HLA-A major histocompatibility complex, class I, A -0.0295475
LOC112694756 uncharaterized LOC112694756 -0.029227
MT1X metallothionein 1X -0.0291731
FSCN1 fascin actin-bundling protein 1 -0.0290379
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0289576
RPL39 ribosomal protein L39 -0.0287339
RPL7 ribosomal protein L7 -0.0287258
S100A2 S100 calcium binding protein A2 -0.0286903