| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.19927 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.106703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0882292 |
| TP63 | tumor protein p63 | 0.0872491 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0734476 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0710775 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0694334 |
| CADM2 | cell adhesion molecule 2 | 0.0682468 |
| PRELID2 | PRELI domain containing 2 | 0.0675664 |
| RNF213 | ring finger protein 213 | 0.0526423 |
| TNS3 | tensin 3 | 0.0517105 |
| FMNL2 | formin-like 2 | 0.0501221 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0495736 |
| RAD51B | RAD51 paralog B | 0.0450267 |
| HLA-B | major histocompatibility complex, class I, B | 0.0437437 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0431875 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0426836 |
| CAPRIN2 | caprin family member 2 | 0.0400079 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0399388 |
| PDE10A | phosphodiesterase 10A | 0.0389228 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0358777 |
| HDAC9 | histone deacetylase 9 | 0.0356676 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0356298 |
| EFNA5 | ephrin-A5 | 0.0351172 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0349634 |
| SMYD3 | SET and MYND domain containing 3 | 0.0347915 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0329945 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0328079 |
| SP100 | SP100 nuclear antigen | 0.0318642 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0311536 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0305771 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0305473 |
| NPAS2 | neuronal PAS domain protein 2 | 0.030001 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0299673 |
| DNER | delta/notch-like EGF repeat containing | 0.0296278 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0289267 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0275757 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0274774 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0268701 |
| EPHA4 | EPH receptor A4 | 0.026788 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0266389 |
| RUNX1 | runt-related transcription factor 1 | 0.0260404 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0259941 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0258486 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0255776 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0249861 |
| TSC22D1 | TSC22 domain family, member 1 | 0.024889 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0248331 |
| MYOF | myoferlin | 0.0242912 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0238036 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0237741 |
| TXNIP | thioredoxin interacting protein | 0.0237211 |
| SDC4 | syndecan 4 | 0.0233826 |
| EXOC4 | exocyst complex component 4 | 0.0230694 |
| TRIM56 | tripartite motif containing 56 | 0.0230256 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0223607 |
| PRKCE | protein kinase C, epsilon | 0.0222378 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0221255 |
| ZNF638 | zinc finger protein 638 | 0.0218316 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0218229 |
| CEP250 | centrosomal protein 250kDa | 0.0213993 |
| B2M | beta-2-microglobulin | 0.0211952 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0210014 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0209479 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0203083 |
| HLA-A | major histocompatibility complex, class I, A | 0.0202266 |
| MEF2A | myocyte enhancer factor 2A | 0.0198749 |
| VEGFA | vascular endothelial growth factor A | 0.0195285 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0192494 |
| PLEC | plectin | 0.0190989 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0186047 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0184965 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0183164 |
| SQSTM1 | sequestosome 1 | 0.0182721 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0182337 |
| ECE1 | endothelin converting enzyme 1 | 0.0182153 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0181696 |
| TMSB4X | thymosin beta 4, X-linked | 0.0181632 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0180877 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0180087 |
| YEATS2 | YEATS domain containing 2 | 0.0178458 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0178415 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0176989 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0176821 |
| AEBP2 | AE binding protein 2 | 0.0176726 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0175832 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0174415 |
| TGM2 | transglutaminase 2 | 0.0174239 |
| PDE8A | phosphodiesterase 8A | 0.0173496 |
| JAK1 | Janus kinase 1 | 0.0173323 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0173246 |
| SLK | STE20-like kinase | 0.0171962 |
| ATM | ATM serine/threonine kinase | 0.0170956 |
| INTS6 | integrator complex subunit 6 | 0.0170267 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0169631 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0167174 |
| PTK2 | protein tyrosine kinase 2 | 0.0165594 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0165557 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0162881 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0161655 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.375944 |
| VIM | vimentin | -0.205965 |
| TXNRD1 | thioredoxin reductase 1 | -0.118415 |
| PTMA | prothymosin, alpha | -0.0852847 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0803637 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0736345 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0709339 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0669757 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0668288 |
| ACTG1 | actin gamma 1 | -0.0656902 |
| RAI1 | retinoic acid induced 1 | -0.0618663 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0612438 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0601299 |
| CENPF | centromere protein F, 350/400kDa | -0.058997 |
| TMSB10 | thymosin beta 10 | -0.0550456 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0541308 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0507352 |
| EGR1 | early growth response 1 | -0.0497285 |
| MT2A | metallothionein 2A | -0.0455954 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0455705 |
| TMEM41B | transmembrane protein 41B | -0.0447931 |
| SRGN | serglycin | -0.0445067 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0433046 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0399318 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0388002 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0369372 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0363541 |
| RTN4 | reticulon 4 | -0.0360816 |
| POTEF | POTE ankyrin domain family, member F | -0.0356467 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0355443 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0344317 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0343637 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0339432 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.033387 |
| FBXO11 | F-box protein 11 | -0.0307965 |
| MKI67 | marker of proliferation Ki-67 | -0.0302474 |
| JMJD1C | jumonji domain containing 1C | -0.0302291 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0301565 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0296718 |
| HMGA1 | high mobility group AT-hook 1 | -0.0289503 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0286182 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0282008 |
| RPS6 | ribosomal protein S6 | -0.0280927 |
| TOP1 | topoisomerase (DNA) I | -0.0279 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0259952 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0251481 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0247535 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0242024 |
| RACK1 | receptor for activated C kinase 1 | -0.0237135 |
| RPL12 | ribosomal protein L12 | -0.0233191 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0228865 |
| RPLP0 | ribosomal protein, large, P0 | -0.022533 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.022433 |
| UPP1 | uridine phosphorylase 1 | -0.0224278 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0221718 |
| YBX1 | Y box binding protein 1 | -0.0220651 |
| RPS8 | ribosomal protein S8 | -0.0218102 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0217858 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0215009 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0214064 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.02122 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.020634 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0206319 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0205869 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0205808 |
| RBM25 | RNA binding motif protein 25 | -0.0202952 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.020281 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0199638 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.019864 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0197393 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0196865 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0196518 |
| CANX | calnexin | -0.019432 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0188646 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0185595 |
| ETNK1 | ethanolamine kinase 1 | -0.0183229 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0183059 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0182565 |
| WASF2 | WAS protein family, member 2 | -0.0181286 |
| ECT2 | epithelial cell transforming 2 | -0.0179369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0177435 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0176904 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0176735 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0176684 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0176253 |
| EREG | epiregulin | -0.0175487 |
| LDHA | lactate dehydrogenase A | -0.0175037 |
| KIF14 | kinesin family member 14 | -0.0174048 |
| RPS24 | ribosomal protein S24 | -0.0173226 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0172185 |
| SGO2 | shugoshin 2 | -0.0170529 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0169358 |
| S100A10 | S100 calcium binding protein A10 | -0.0169236 |
| BSG | basigin (Ok blood group) | -0.0169086 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0169049 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0167765 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0167217 |
| RPL8 | ribosomal protein L8 | -0.0166773 |
| CEP170 | centrosomal protein 170kDa | -0.0166342 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0165468 |
