| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.169078 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.126834 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.103392 |
| PRELID2 | PRELI domain containing 2 | 0.064463 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0643614 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0625146 |
| FN1 | fibronectin 1 | 0.0623823 |
| MYO1E | myosin IE | 0.0606307 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0567723 |
| MYOF | myoferlin | 0.053378 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0512451 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0506425 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0491045 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0490237 |
| VEGFA | vascular endothelial growth factor A | 0.048389 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0477926 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0473369 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0458613 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0457316 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.045141 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0448652 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0447999 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.044449 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0418572 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0418104 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0411041 |
| VCL | vinculin | 0.0408563 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0405207 |
| PTGES2 | prostaglandin E synthase 2 | 0.0403811 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0386604 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0386401 |
| PTK2 | protein tyrosine kinase 2 | 0.0385012 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0382505 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0381326 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0380881 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0377987 |
| FAT1 | FAT atypical cadherin 1 | 0.0376621 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0375514 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0360629 |
| COPA | coatomer protein complex, subunit alpha | 0.0360132 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0358735 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357755 |
| CDH13 | cadherin 13 | 0.0355093 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0351079 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.035058 |
| ANKRD11 | ankyrin repeat domain 11 | 0.034742 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0344334 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0340654 |
| MAP4 | microtubule-associated protein 4 | 0.0339548 |
| CUL3 | cullin 3 | 0.033877 |
| SP100 | SP100 nuclear antigen | 0.0336314 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0335201 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.033372 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.033349 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0331955 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0328898 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0322521 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0322082 |
| JAK1 | Janus kinase 1 | 0.0320485 |
| RNF24 | ring finger protein 24 | 0.0315373 |
| ACTN4 | actinin, alpha 4 | 0.0313412 |
| CEP192 | centrosomal protein 192kDa | 0.031201 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0310175 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0305598 |
| SMAD2 | SMAD family member 2 | 0.030153 |
| ATXN1 | ataxin 1 | 0.0300315 |
| LAMA4 | laminin, alpha 4 | 0.0299501 |
| HDLBP | high density lipoprotein binding protein | 0.0298761 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.029726 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0295739 |
| ACTN1 | actinin, alpha 1 | 0.0294758 |
| RAB2A | RAB2A, member RAS oncogene family | 0.029472 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0294586 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0294557 |
| UTRN | utrophin | 0.0293835 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0292095 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0287801 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0287542 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0286626 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0286166 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0284737 |
| PGK1 | phosphoglycerate kinase 1 | 0.0282651 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0281797 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.028037 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.027812 |
| NKTR | natural killer cell triggering receptor | 0.0276911 |
| FAM193A | family with sequence similarity 193, member A | 0.0275001 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0273953 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0270862 |
| PYGL | phosphorylase, glycogen, liver | 0.0269443 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0268859 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0267903 |
| NCKAP1 | NCK-associated protein 1 | 0.0266835 |
| AOPEP | aminopeptidase O (putative) | 0.0264837 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0264021 |
| HDAC4 | histone deacetylase 4 | 0.0263037 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0262722 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0262683 |
| DST | dystonin | 0.0262587 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.026044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.166614 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.131136 |
| TXNRD1 | thioredoxin reductase 1 | -0.130829 |
| ATOSA | atos homolog A | -0.110857 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0908085 |
| LAMB3 | laminin, beta 3 | -0.0769525 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0661144 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0622499 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0616443 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.06079 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0579291 |
| TXNIP | thioredoxin interacting protein | -0.0565212 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0555755 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0514263 |
| IGF2 | insulin-like growth factor 2 | -0.0513601 |
| FOXP1 | forkhead box P1 | -0.0502912 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0497217 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0496861 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0487039 |
| HMGA2 | high mobility group AT-hook 2 | -0.0486408 |
| FAM13A | family with sequence similarity 13, member A | -0.0471264 |
| TUSC3 | tumor suppressor candidate 3 | -0.0466033 |
| MUC16 | mucin 16, cell surface associated | -0.0463006 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0462261 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0461318 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0459523 |
| STC1 | stanniocalcin 1 | -0.0456838 |
| EGFR | epidermal growth factor receptor | -0.044586 |
| ABHD17C | abhydrolase domain containing 17C | -0.0443717 |
| FTL | ferritin, light polypeptide | -0.0443265 |
| TJP1 | tight junction protein 1 | -0.0437843 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0437412 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0437296 |
| ACTG1 | actin gamma 1 | -0.0430634 |
| AHNAK | AHNAK nucleoprotein | -0.0429349 |
| USP3 | ubiquitin specific peptidase 3 | -0.0425508 |
| SPAG9 | sperm associated antigen 9 | -0.0425287 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0418472 |
| RUNX1 | runt-related transcription factor 1 | -0.0412073 |
| CCNI | cyclin I | -0.0396761 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0390062 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.03899 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0382952 |
| TULP4 | tubby like protein 4 | -0.0382866 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0377421 |
| RPL31 | ribosomal protein L31 | -0.0376946 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0366327 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0360364 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.03577 |
| PARD3 | par-3 family cell polarity regulator | -0.0346416 |
| TNPO1 | transportin 1 | -0.0346401 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0343513 |
| RBM47 | RNA binding motif protein 47 | -0.0342796 |
| NF1 | neurofibromin 1 | -0.0342144 |
| ABHD3 | abhydrolase domain containing 3 | -0.0341718 |
| CUX1 | cut-like homeobox 1 | -0.0340898 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0340436 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0340145 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.033846 |
| OGA | O-GlcNAcase | -0.0336754 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0335996 |
| MYO5C | myosin VC | -0.033328 |
| NEBL | nebulette | -0.0333072 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.033251 |
| RPS6 | ribosomal protein S6 | -0.0329306 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0328695 |
| TCF12 | transcription factor 12 | -0.0325714 |
| KLF6 | Kruppel-like factor 6 | -0.0321089 |
| CLMP | CXADR-like membrane protein | -0.032084 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0318428 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0315309 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.031397 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0313941 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0313588 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0311816 |
| MED13 | mediator complex subunit 13 | -0.0310933 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0308737 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0307566 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.030497 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0304913 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0304644 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0304259 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0303911 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0303894 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0303771 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0303447 |
| ATP6V0D2 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 | -0.0299887 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0299634 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0298785 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0297543 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0297008 |
| ANXA2 | annexin A2 | -0.0296639 |
| UBAP1 | ubiquitin associated protein 1 | -0.029505 |
| SSH2 | slingshot protein phosphatase 2 | -0.0295003 |
| SQSTM1 | sequestosome 1 | -0.0293823 |
| RPL35A | ribosomal protein L35a | -0.0293385 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0290302 |
| TJP2 | tight junction protein 2 | -0.0290253 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0289775 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0289153 |
