| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.141033 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.096402 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0912976 |
| INTS6 | integrator complex subunit 6 | 0.0827756 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0765774 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.075895 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0741866 |
| GRAMD1B | GRAM domain containing 1B | 0.0725631 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0723071 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0710967 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0692849 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0689524 |
| AEBP2 | AE binding protein 2 | 0.0685606 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0679677 |
| RAD51B | RAD51 paralog B | 0.0667868 |
| PRELID2 | PRELI domain containing 2 | 0.0666142 |
| VCL | vinculin | 0.0651115 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0642717 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0637068 |
| PDLIM5 | PDZ and LIM domain 5 | 0.061738 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0603778 |
| PDE10A | phosphodiesterase 10A | 0.0588943 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0578941 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0568218 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0567074 |
| ATXN1 | ataxin 1 | 0.0564969 |
| DST | dystonin | 0.0556834 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0556112 |
| EXOC4 | exocyst complex component 4 | 0.0549307 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0547938 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0506896 |
| POTEF | POTE ankyrin domain family, member F | 0.0485444 |
| HOMER1 | homer scaffolding protein 1 | 0.0472761 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0469974 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0454882 |
| WWOX | WW domain containing oxidoreductase | 0.0454316 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0450785 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0448899 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0443524 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0443136 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0439181 |
| BRD2 | bromodomain containing 2 | 0.0438356 |
| SMYD3 | SET and MYND domain containing 3 | 0.0430169 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0419268 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0404349 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0403686 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0396133 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0392029 |
| NABP1 | nucleic acid binding protein 1 | 0.0391407 |
| TLN1 | talin 1 | 0.0390337 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0390231 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0390218 |
| HDAC4 | histone deacetylase 4 | 0.0387186 |
| SMAD3 | SMAD family member 3 | 0.0385385 |
| YAP1 | Yes-associated protein 1 | 0.0383505 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0376149 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0371436 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0367698 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.036077 |
| CPNE1 | copine I | 0.035959 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0353669 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0352836 |
| TPM3 | tropomyosin 3 | 0.034022 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.033786 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0333803 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0333084 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0333041 |
| NLGN1 | neuroligin 1 | 0.0332938 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0330344 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0317085 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0316864 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0313904 |
| NEK10 | NIMA-related kinase 10 | 0.030744 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0303142 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0300274 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.029899 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0293195 |
| SETD5 | SET domain containing 5 | 0.0292792 |
| FMNL2 | formin-like 2 | 0.0292676 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0291886 |
| RPL3 | ribosomal protein L3 | 0.029105 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.028868 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0285696 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0284044 |
| COPA | coatomer protein complex, subunit alpha | 0.0281448 |
| PYGL | phosphorylase, glycogen, liver | 0.0281391 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0279676 |
| PLEC | plectin | 0.0279494 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0278815 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0277453 |
| PRKCE | protein kinase C, epsilon | 0.0275556 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0274745 |
| GON4L | gon-4-like (C. elegans) | 0.0274267 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0273632 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0272346 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0270999 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0269279 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0269203 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0266943 |
| ANO6 | anoctamin 6 | 0.0266196 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.131866 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0921648 |
| TXNRD1 | thioredoxin reductase 1 | -0.0768221 |
| PTMA | prothymosin, alpha | -0.0707348 |
| TMSB10 | thymosin beta 10 | -0.0642653 |
| VIM | vimentin | -0.0639685 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0472167 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0466559 |
| RPL26 | ribosomal protein L26 | -0.0463107 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0449801 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0427839 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0416066 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0415589 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0414162 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0387979 |
| RPL12 | ribosomal protein L12 | -0.0385645 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0380522 |
| MT2A | metallothionein 2A | -0.0368305 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0362974 |
| SEPTIN7 | septin 7 | -0.0359204 |
| RPS24 | ribosomal protein S24 | -0.0336643 |
| CAVIN1 | caveolae associated protein 1 | -0.0334854 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0332786 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0325338 |
| GNAS | GNAS complex locus | -0.0322908 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0320294 |
| IER3 | immediate early response 3 | -0.0312313 |
| RTN4 | reticulon 4 | -0.0312073 |
| RPL37A | ribosomal protein L37a | -0.0310434 |
| RPS8 | ribosomal protein S8 | -0.0308872 |
| RPS21 | ribosomal protein S21 | -0.030825 |
| RPL34 | ribosomal protein L34 | -0.0305228 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0298583 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0297401 |
| RPS27A | ribosomal protein S27a | -0.0294473 |
| RPLP0 | ribosomal protein, large, P0 | -0.0294146 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0293017 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0291596 |
| RPL35A | ribosomal protein L35a | -0.0284236 |
| HMGA1 | high mobility group AT-hook 1 | -0.0284099 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0283964 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0282234 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280821 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0278694 |
| PHIP | pleckstrin homology domain interacting protein | -0.0272907 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0265906 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0259888 |
| RPL37 | ribosomal protein L37 | -0.0259121 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0252092 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0251482 |
| TPI1 | triosephosphate isomerase 1 | -0.0249872 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0247692 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0245901 |
| ZFR | zinc finger RNA binding protein | -0.0243582 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0243271 |
| NOP58 | NOP58 ribonucleoprotein | -0.0242294 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0241104 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0238717 |
| UBB | ubiquitin B | -0.0238502 |
| RACK1 | receptor for activated C kinase 1 | -0.0238359 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0236991 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0236349 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0230523 |
| EPN2 | epsin 2 | -0.0230428 |
| H3-3B | H3.3 histone B | -0.0230401 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0228688 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0224407 |
| RPL36A | ribosomal protein L36a | -0.0223294 |
| RPS6 | ribosomal protein S6 | -0.0222673 |
| S100A6 | S100 calcium binding protein A6 | -0.0221414 |
| SRP72 | signal recognition particle 72kDa | -0.0219283 |
| SGO2 | shugoshin 2 | -0.0217299 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0216858 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0214718 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0213779 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.021317 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0208967 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0207941 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0206943 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0205733 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0204415 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0204323 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0204207 |
| RPL11 | ribosomal protein L11 | -0.0202819 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0200614 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0197873 |
| RPLP2 | ribosomal protein, large, P2 | -0.0197724 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0196382 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0195907 |
| HLA-B | major histocompatibility complex, class I, B | -0.019587 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0193132 |
| B2M | beta-2-microglobulin | -0.0192926 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.019285 |
| KLF6 | Kruppel-like factor 6 | -0.0192826 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0192359 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0191724 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.01913 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0191224 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0190604 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0189773 |
