| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.252097 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.196497 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.145135 |
| GRB10 | growth factor receptor-bound protein 10 | 0.11854 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.108813 |
| VEGFA | vascular endothelial growth factor A | 0.106338 |
| AHNAK | AHNAK nucleoprotein | 0.0965289 |
| LAMB3 | laminin, beta 3 | 0.094694 |
| PLEC | plectin | 0.0936643 |
| TMSB4X | thymosin beta 4, X-linked | 0.0821484 |
| CANX | calnexin | 0.081977 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.077233 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0736053 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0700274 |
| DSPP | dentin sialophosphoprotein | 0.0665201 |
| ACTG1 | actin gamma 1 | 0.0609053 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0608551 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0598812 |
| LMO7 | LIM domain 7 | 0.0564882 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0542672 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.051883 |
| RPL4 | ribosomal protein L4 | 0.0514084 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0513485 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0503996 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0480755 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0468327 |
| CTBP2 | C-terminal binding protein 2 | 0.0467924 |
| TPM4 | tropomyosin 4 | 0.0466423 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0450785 |
| DUSP10 | dual specificity phosphatase 10 | 0.0446588 |
| HLA-B | major histocompatibility complex, class I, B | 0.0440871 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0437494 |
| IRF6 | interferon regulatory factor 6 | 0.0431704 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0429731 |
| CD109 | CD109 molecule | 0.0428833 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0427125 |
| COPA | coatomer protein complex, subunit alpha | 0.042642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0420468 |
| NAV2 | neuron navigator 2 | 0.0418244 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.041209 |
| HDLBP | high density lipoprotein binding protein | 0.0411526 |
| POTEF | POTE ankyrin domain family, member F | 0.0403376 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0399548 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0398687 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0397729 |
| KRT8 | keratin 8, type II | 0.0389052 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0377054 |
| SDC4 | syndecan 4 | 0.0372377 |
| PTK2 | protein tyrosine kinase 2 | 0.0368324 |
| EFNA5 | ephrin-A5 | 0.0357697 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0356113 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0353554 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0352287 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0350557 |
| MYO5B | myosin VB | 0.034974 |
| RNF213 | ring finger protein 213 | 0.0349646 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0344679 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.034264 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0339513 |
| ANXA2 | annexin A2 | 0.0338633 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0338172 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0337259 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0336074 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.033272 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0330092 |
| MSI2 | musashi RNA-binding protein 2 | 0.0327173 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0324917 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0323137 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0323086 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318314 |
| RCOR1 | REST corepressor 1 | 0.0316981 |
| AFF4 | AF4/FMR2 family, member 4 | 0.031549 |
| FNBP1L | formin binding protein 1-like | 0.0310376 |
| EZR | ezrin | 0.031037 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0306005 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0305493 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.030503 |
| YBX1 | Y box binding protein 1 | 0.0304125 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0301413 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0299994 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298449 |
| CALR | calreticulin | 0.0294925 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.02941 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0290425 |
| JUN | jun proto-oncogene | 0.0288467 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0286149 |
| NIBAN2 | niban apoptosis regulator 2 | 0.02858 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0284127 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0282124 |
| APP | amyloid beta (A4) precursor protein | 0.0281113 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.028028 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0279183 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0276677 |
| LDHA | lactate dehydrogenase A | 0.0276481 |
| MYO6 | myosin VI | 0.0273199 |
| MAP1B | microtubule-associated protein 1B | 0.0269221 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0266444 |
| TAOK1 | TAO kinase 1 | 0.0264625 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0264327 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0263831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.241277 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.112928 |
| NDRG1 | N-myc downstream regulated 1 | -0.097726 |
| S100A6 | S100 calcium binding protein A6 | -0.0895358 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0656218 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0637405 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0607464 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0606939 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0592414 |
| MT2A | metallothionein 2A | -0.0584718 |
| HMGA1 | high mobility group AT-hook 1 | -0.0562698 |
| RPS2 | ribosomal protein S2 | -0.051919 |
| RPS23 | ribosomal protein S23 | -0.0472413 |
| TMSB10 | thymosin beta 10 | -0.0467287 |
| ASPH | aspartate beta-hydroxylase | -0.0465317 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0438087 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0430599 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0429437 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0422566 |
| RPL11 | ribosomal protein L11 | -0.0412785 |
| RPL32 | ribosomal protein L32 | -0.0409749 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0404917 |
| RPL34 | ribosomal protein L34 | -0.0402232 |
| TFG | TRK-fused gene | -0.0401798 |
| RPS24 | ribosomal protein S24 | -0.039666 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0392878 |
| RPL9 | ribosomal protein L9 | -0.0380678 |
| AREG | amphiregulin | -0.0379654 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0371386 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.036528 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0361969 |
| RPL7 | ribosomal protein L7 | -0.0349958 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0341303 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0329542 |
| RPL19 | ribosomal protein L19 | -0.0326985 |
| S100A10 | S100 calcium binding protein A10 | -0.0316053 |
| UBC | ubiquitin C | -0.0312265 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0308124 |
| GOLGA4 | golgin A4 | -0.0305765 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302249 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.029643 |
| CCNI | cyclin I | -0.029597 |
| RPL15 | ribosomal protein L15 | -0.0293536 |
| TRAM1 | translocation associated membrane protein 1 | -0.0293152 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0290696 |
| RPLP2 | ribosomal protein, large, P2 | -0.0288275 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0288245 |
| TUBA1B | tubulin, alpha 1b | -0.0285305 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0284688 |
| RPS6 | ribosomal protein S6 | -0.0283235 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0282258 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0280316 |
| DSTN | destrin (actin depolymerizing factor) | -0.0267783 |
| RPS13 | ribosomal protein S13 | -0.0266424 |
| SMC4 | structural maintenance of chromosomes 4 | -0.026451 |
| RPS15 | ribosomal protein S15 | -0.0261342 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0259914 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0259095 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0258659 |
| H1-4 | H1.4 linker histone, cluster member | -0.0256436 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.02556 |
| EREG | epiregulin | -0.0254741 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0254181 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0248605 |
| RASA2 | RAS p21 protein activator 2 | -0.0247808 |
| RPS25 | ribosomal protein S25 | -0.0247477 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0240173 |
| NKTR | natural killer cell triggering receptor | -0.0239825 |
| RYBP | RING1 and YY1 binding protein | -0.0236577 |
| FAM162A | family with sequence similarity 162, member A | -0.0236068 |
| MKI67 | marker of proliferation Ki-67 | -0.0234416 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0232882 |
| RPS21 | ribosomal protein S21 | -0.0230788 |
| FHIT | fragile histidine triad | -0.0228474 |
| RPS14 | ribosomal protein S14 | -0.0228144 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0227819 |
| GOLT1B | golgi transport 1B | -0.0226552 |
| RPS19 | ribosomal protein S19 | -0.0225619 |
| CLINT1 | clathrin interactor 1 | -0.0224379 |
| RPL28 | ribosomal protein L28 | -0.0213738 |
| CDC42 | cell division cycle 42 | -0.0212575 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0212537 |
| TXNRD1 | thioredoxin reductase 1 | -0.0212537 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0209916 |
| HMGB2 | high mobility group box 2 | -0.0209628 |
| CCND1 | cyclin D1 | -0.0208955 |
| RPL36A | ribosomal protein L36a | -0.0208494 |
| RPS8 | ribosomal protein S8 | -0.0208273 |
| TMEM263 | transmembrane protein 263 | -0.0208229 |
| RPL6 | ribosomal protein L6 | -0.0206996 |
| IL6ST | interleukin 6 signal transducer | -0.0206573 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0204146 |
| RPL30 | ribosomal protein L30 | -0.0201479 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0200624 |
| SCEL | sciellin | -0.0200354 |
| RPL12 | ribosomal protein L12 | -0.0198913 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0197209 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0193908 |
| CDK17 | cyclin-dependent kinase 17 | -0.0193736 |
| CTSD | cathepsin D | -0.0192421 |
