| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Salicylic acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.190013 |
| DST | dystonin | 0.133848 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.132426 |
| KYNU | kynureninase | 0.128111 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.116773 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.105192 |
| VCL | vinculin | 0.0990273 |
| PDE10A | phosphodiesterase 10A | 0.0929718 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0927575 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0843769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0832355 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0763883 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0743346 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0741664 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0662125 |
| MYOF | myoferlin | 0.0655243 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0654912 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0612982 |
| INTS6 | integrator complex subunit 6 | 0.0603745 |
| EPHA4 | EPH receptor A4 | 0.0601808 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0600894 |
| SMAD2 | SMAD family member 2 | 0.0593343 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0583049 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0582689 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0567815 |
| MCL1 | myeloid cell leukemia 1 | 0.0545855 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0543272 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0525056 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0519729 |
| ASPH | aspartate beta-hydroxylase | 0.051657 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0514436 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0503024 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.049745 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0494703 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0489248 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0484766 |
| PRELID2 | PRELI domain containing 2 | 0.0481501 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0404187 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0393071 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0363481 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0357309 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0356018 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0351878 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0346786 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0346396 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0341333 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0339424 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0330534 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.032881 |
| DNER | delta/notch-like EGF repeat containing | 0.0326628 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0325507 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0320222 |
| FAM107B | family with sequence similarity 107, member B | 0.0319964 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0319553 |
| ANXA1 | annexin A1 | 0.031573 |
| SPAG9 | sperm associated antigen 9 | 0.0313756 |
| RBM39 | RNA binding motif protein 39 | 0.0312837 |
| BMP6 | bone morphogenetic protein 6 | 0.0308202 |
| GRAMD1B | GRAM domain containing 1B | 0.030713 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0304835 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0303284 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.030296 |
| ATXN1 | ataxin 1 | 0.0295457 |
| CTBP2 | C-terminal binding protein 2 | 0.0291195 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0289574 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0286588 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0284679 |
| HDAC4 | histone deacetylase 4 | 0.0280277 |
| YBX3 | Y box binding protein 3 | 0.0276013 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0274357 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0273911 |
| RPL4 | ribosomal protein L4 | 0.0266992 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0266876 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0266447 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0265021 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0262316 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0260985 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.02589 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0255667 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0254668 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.025162 |
| ZNF638 | zinc finger protein 638 | 0.0250038 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.0248081 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0247994 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0247423 |
| IL6 | interleukin 6 | 0.0245731 |
| RCOR1 | REST corepressor 1 | 0.0245136 |
| MORF4L2 | mortality factor 4 like 2 | 0.0240221 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0238446 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0237945 |
| RLIM | ring finger protein, LIM domain interacting | 0.0236578 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0235134 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0231253 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0230757 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0230542 |
| LAMA1 | laminin, alpha 1 | 0.0230498 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0229958 |
| ECT2 | epithelial cell transforming 2 | 0.0226758 |
| SETX | senataxin | 0.0224022 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.335136 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.141019 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.110813 |
| VIM | vimentin | -0.103723 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.102834 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.101693 |
| RPS6 | ribosomal protein S6 | -0.0842322 |
| GDA | guanine deaminase | -0.0787453 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0720547 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0670077 |
| RPL26 | ribosomal protein L26 | -0.0634943 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0611717 |
| RPS12 | ribosomal protein S12 | -0.0606578 |
| CTSL | cathepsin L | -0.0598029 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0589626 |
| SMYD3 | SET and MYND domain containing 3 | -0.0572774 |
| RPLP1 | ribosomal protein, large, P1 | -0.0543099 |
| RPS3 | ribosomal protein S3 | -0.0535824 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0534635 |
| TXNRD1 | thioredoxin reductase 1 | -0.0534165 |
| PTGR1 | prostaglandin reductase 1 | -0.0534128 |
| RPS2 | ribosomal protein S2 | -0.0515374 |
| OSMR | oncostatin M receptor | -0.0507724 |
| PCBP3 | poly(rC) binding protein 3 | -0.0493469 |
| FTL | ferritin, light polypeptide | -0.0488542 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0473473 |
| RPL31 | ribosomal protein L31 | -0.0473307 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0469541 |
| CDH13 | cadherin 13 | -0.0463552 |
| PTMA | prothymosin, alpha | -0.0447478 |
| PYGL | phosphorylase, glycogen, liver | -0.0435328 |
| RPL36A | ribosomal protein L36a | -0.0430593 |
| RPL37A | ribosomal protein L37a | -0.0425813 |
| RPL12 | ribosomal protein L12 | -0.0417353 |
| RPS8 | ribosomal protein S8 | -0.041225 |
| NCKAP5 | NCK-associated protein 5 | -0.040971 |
| RPS27 | ribosomal protein S27 | -0.0405031 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0391527 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0379078 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0375223 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0374643 |
| COL5A2 | collagen, type V, alpha 2 | -0.0367591 |
| ENO1 | enolase 1, (alpha) | -0.0362394 |
| RPL9 | ribosomal protein L9 | -0.0361545 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0360157 |
| RPL37 | ribosomal protein L37 | -0.0359413 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0358432 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0358411 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0357308 |
| NRCAM | neuronal cell adhesion molecule | -0.03573 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0354253 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0349357 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0348078 |
| RPS27A | ribosomal protein S27a | -0.034571 |
| RPS19 | ribosomal protein S19 | -0.034477 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0342482 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0342193 |
| BMERB1 | bMERB domain containing 1 | -0.0341173 |
| EFNA5 | ephrin-A5 | -0.0334782 |
| RANBP17 | RAN binding protein 17 | -0.0332103 |
| RACK1 | receptor for activated C kinase 1 | -0.0330633 |
| TENM3 | teneurin transmembrane protein 3 | -0.0328374 |
| RPS29 | ribosomal protein S29 | -0.0323247 |
| MFF | mitochondrial fission factor | -0.0320847 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0318882 |
| MAP1B | microtubule-associated protein 1B | -0.0312616 |
| S100A6 | S100 calcium binding protein A6 | -0.0307339 |
| STC1 | stanniocalcin 1 | -0.0304073 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302143 |
| RPL11 | ribosomal protein L11 | -0.0299678 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0298653 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0293323 |
| RTN4 | reticulon 4 | -0.0287257 |
| AOPEP | aminopeptidase O (putative) | -0.0285043 |
| CEP170 | centrosomal protein 170kDa | -0.0279284 |
| RPL19 | ribosomal protein L19 | -0.0271862 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0271743 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269083 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.026836 |
| SCCPDH | saccharopine dehydrogenase (putative) | -0.0268089 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0266521 |
| CRLF2 | cytokine receptor-like factor 2 | -0.0261338 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0258977 |
| RPS14 | ribosomal protein S14 | -0.0257251 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0256591 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0255292 |
| RAI1 | retinoic acid induced 1 | -0.0254314 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0253771 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0253081 |
| TBXT | T-box transcription factor T | -0.0251431 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0244726 |
| RAI14 | retinoic acid induced 14 | -0.0244594 |
| LAMB1 | laminin, beta 1 | -0.0242258 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0241187 |
| TNPO1 | transportin 1 | -0.0240011 |
| PCDH9 | protocadherin 9 | -0.0239184 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0238263 |
| KLHL5 | kelch-like family member 5 | -0.0234591 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0234202 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0229865 |
