| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.103932 |
| PHIP | pleckstrin homology domain interacting protein | 0.0828212 |
| DST | dystonin | 0.0783029 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0778974 |
| FNDC3B | fibronectin type III domain containing 3B | 0.075554 |
| ITGAV | integrin, alpha V | 0.0733851 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0637874 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0606302 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0605463 |
| COL5A2 | collagen, type V, alpha 2 | 0.0517643 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0503971 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0459626 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0454655 |
| RCOR1 | REST corepressor 1 | 0.0421959 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0410807 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0401681 |
| ATXN2 | ataxin 2 | 0.0399474 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0397652 |
| LRRC4C | leucine rich repeat containing 4C | 0.0386964 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0386089 |
| TSC22D2 | TSC22 domain family, member 2 | 0.037595 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0372657 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0372595 |
| PCDH9 | protocadherin 9 | 0.037059 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0359158 |
| NHSL1 | NHS-like 1 | 0.035801 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0354309 |
| PRELID2 | PRELI domain containing 2 | 0.0353593 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0342104 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0340126 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.033842 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0334207 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0332158 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0328324 |
| ZNF608 | zinc finger protein 608 | 0.0325808 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0325133 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0325088 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.032325 |
| PHF21A | PHD finger protein 21A | 0.0313075 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.030664 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0304247 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0298173 |
| PARD3B | par-3 family cell polarity regulator beta | 0.029668 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0296032 |
| NCOA1 | nuclear receptor coactivator 1 | 0.028728 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0285858 |
| EFNA5 | ephrin-A5 | 0.0285613 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0279524 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0277844 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0270005 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0269702 |
| MED13L | mediator complex subunit 13-like | 0.0268118 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266638 |
| NTM | neurotrimin | 0.0264821 |
| NFIA | nuclear factor I/A | 0.0260007 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0259799 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0258319 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0258062 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0257268 |
| EXOC6B | exocyst complex component 6B | 0.0256969 |
| RASAL2 | RAS protein activator like 2 | 0.0254683 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0253592 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0253209 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0249744 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.024879 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0247755 |
| ANK2 | ankyrin 2, neuronal | 0.0244485 |
| OGA | O-GlcNAcase | 0.0241419 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0240052 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0239657 |
| TENM3 | teneurin transmembrane protein 3 | 0.02394 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0238607 |
| UBE3C | ubiquitin protein ligase E3C | 0.0234389 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0234276 |
| COG5 | component of oligomeric golgi complex 5 | 0.0229505 |
| LPIN2 | lipin 2 | 0.0229401 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0228866 |
| GSE1 | Gse1 coiled-coil protein | 0.0228424 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0223597 |
| XPO1 | exportin 1 | 0.0221651 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0221246 |
| MEIS2 | Meis homeobox 2 | 0.0219498 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218968 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0217482 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0216955 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0216414 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0215261 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0213796 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.021289 |
| ZNF292 | zinc finger protein 292 | 0.0212023 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020934 |
| VEGFA | vascular endothelial growth factor A | 0.0207577 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0204529 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0204328 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0204204 |
| PCNX1 | pecanex 1 | 0.0203891 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0201163 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.020045 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0200444 |
| RANBP9 | RAN binding protein 9 | 0.0200112 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.19593 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.113381 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.09263 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0924374 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0921468 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0855746 |
| PEG10 | paternally expressed 10 | -0.0791674 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.066354 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0572155 |
| GNAS | GNAS complex locus | -0.055418 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0536313 |
| GPC3 | glypican 3 | -0.0530676 |
| CENPF | centromere protein F, 350/400kDa | -0.0505081 |
| METAP2 | methionyl aminopeptidase 2 | -0.0502203 |
| RPS8 | ribosomal protein S8 | -0.0442703 |
| RPS16 | ribosomal protein S16 | -0.0432639 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0432363 |
| RPS6 | ribosomal protein S6 | -0.0414107 |
| MKI67 | marker of proliferation Ki-67 | -0.0412339 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0408923 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0406973 |
| ACTG1 | actin gamma 1 | -0.0395239 |
| RPL11 | ribosomal protein L11 | -0.0394468 |
| NRG1 | neuregulin 1 | -0.0393765 |
| NOP58 | NOP58 ribonucleoprotein | -0.03808 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0365399 |
| PTMA | prothymosin, alpha | -0.036098 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0354098 |
| PFN1 | profilin 1 | -0.0353405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0349619 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0347611 |
| RPS24 | ribosomal protein S24 | -0.0345864 |
| KPNB1 | karyopherin (importin) beta 1 | -0.03437 |
| RPL35A | ribosomal protein L35a | -0.0331458 |
| CAVIN1 | caveolae associated protein 1 | -0.0324947 |
| RPL26 | ribosomal protein L26 | -0.0317868 |
| ZNF385D | zinc finger protein 385D | -0.030844 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.030792 |
| HMGA1 | high mobility group AT-hook 1 | -0.030024 |
| ENAH | enabled homolog (Drosophila) | -0.029909 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0298493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0296512 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0279153 |
| EMP1 | epithelial membrane protein 1 | -0.02786 |
| HMGB1 | high mobility group box 1 | -0.0272517 |
| TMSB4X | thymosin beta 4, X-linked | -0.0270201 |
| MAP4 | microtubule-associated protein 4 | -0.0268929 |
| FBL | fibrillarin | -0.0266843 |
| RPS3 | ribosomal protein S3 | -0.0266199 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0265484 |
| CENPE | centromere protein E, 312kDa | -0.0265103 |
| RPL23 | ribosomal protein L23 | -0.0263897 |
| RPL37 | ribosomal protein L37 | -0.0261819 |
| BPTF | bromodomain PHD finger transcription factor | -0.0260392 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0260357 |
| FBXO27 | F-box protein 27 | -0.0259885 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0259298 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0258434 |
| HMGB2 | high mobility group box 2 | -0.0257912 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0255518 |
| MTDH | metadherin | -0.0253316 |
| RPS12 | ribosomal protein S12 | -0.0247255 |
| COL1A2 | collagen, type I, alpha 2 | -0.0244915 |
| CPA6 | carboxypeptidase A6 | -0.0243484 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0243448 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0242769 |
| PCBP2 | poly(rC) binding protein 2 | -0.023473 |
| RPL19 | ribosomal protein L19 | -0.0234429 |
| FTL | ferritin, light polypeptide | -0.0233809 |
| ANXA2 | annexin A2 | -0.0233462 |
| RAI1 | retinoic acid induced 1 | -0.0227029 |
| RPLP0 | ribosomal protein, large, P0 | -0.0226004 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0225862 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0225182 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0224794 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0224266 |
| WDR43 | WD repeat domain 43 | -0.0220139 |
| TMSB10 | thymosin beta 10 | -0.0218409 |
| RPL37A | ribosomal protein L37a | -0.0217965 |
| USP3 | ubiquitin specific peptidase 3 | -0.0211481 |
| BSG | basigin (Ok blood group) | -0.0208817 |
| RPL12 | ribosomal protein L12 | -0.0208312 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0205755 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0204937 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0203838 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0202069 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0199907 |
| EVI5 | ecotropic viral integration site 5 | -0.0198929 |
| CLTC | clathrin, heavy chain (Hc) | -0.0197678 |
| TPX2 | TPX2, microtubule-associated | -0.0196341 |
| CERT1 | ceramide transporter 1 | -0.019566 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0195541 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.019476 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0192713 |
| RPL9 | ribosomal protein L9 | -0.0192491 |
| RPS27A | ribosomal protein S27a | -0.0190368 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0188226 |
| DSTN | destrin (actin depolymerizing factor) | -0.0187664 |
| MATR3 | matrin 3 | -0.0187023 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0186762 |
