| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.304663 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0723946 |
| MCL1 | myeloid cell leukemia 1 | 0.0711311 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0689823 |
| ASPH | aspartate beta-hydroxylase | 0.0647955 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0644792 |
| INTS6 | integrator complex subunit 6 | 0.0628863 |
| VMP1 | vacuole membrane protein 1 | 0.0622543 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0604269 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0592123 |
| ITGAV | integrin, alpha V | 0.0589811 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0583341 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0520896 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0508172 |
| ATXN1 | ataxin 1 | 0.0505258 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0494035 |
| BRD2 | bromodomain containing 2 | 0.0470961 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0451875 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0427539 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0422989 |
| NUP98 | nucleoporin 98kDa | 0.0417153 |
| ANO6 | anoctamin 6 | 0.0405621 |
| CCNL1 | cyclin L1 | 0.040217 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0401266 |
| PDLIM5 | PDZ and LIM domain 5 | 0.039942 |
| VEGFA | vascular endothelial growth factor A | 0.0391049 |
| JMJD1C | jumonji domain containing 1C | 0.0388901 |
| SEPTIN9 | septin 9 | 0.0385769 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0374926 |
| MSN | moesin | 0.0365601 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0362162 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0361518 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0339822 |
| MYO1E | myosin IE | 0.0337646 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0334346 |
| AFDN | afadin, adherens junction formation factor | 0.0325063 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320293 |
| RBM39 | RNA binding motif protein 39 | 0.0318697 |
| RRM2 | ribonucleotide reductase M2 | 0.0312927 |
| EGR1 | early growth response 1 | 0.0304196 |
| ATF6 | activating transcription factor 6 | 0.0301063 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0298298 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0297092 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0292419 |
| ZNF644 | zinc finger protein 644 | 0.0290367 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0289697 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0285843 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0285016 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0284892 |
| PRELID2 | PRELI domain containing 2 | 0.028489 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0281479 |
| HDAC9 | histone deacetylase 9 | 0.027967 |
| ZFP36 | ZFP36 ring finger protein | 0.0275382 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0273178 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0269788 |
| SMAD3 | SMAD family member 3 | 0.0264901 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0262994 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0261273 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0261134 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0258319 |
| YAP1 | Yes-associated protein 1 | 0.0257886 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0257115 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0256452 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0256058 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0252266 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0250241 |
| DENND5A | DENN/MADD domain containing 5A | 0.0247892 |
| SETD5 | SET domain containing 5 | 0.0247036 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0246337 |
| SFTPA2 | surfactant protein A2 | 0.0240744 |
| HOMER1 | homer scaffolding protein 1 | 0.0240126 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0238632 |
| OGA | O-GlcNAcase | 0.023463 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0233204 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0233096 |
| UBAP2 | ubiquitin associated protein 2 | 0.0227407 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0225344 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0225068 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0223328 |
| SMYD3 | SET and MYND domain containing 3 | 0.02231 |
| TOP1 | topoisomerase (DNA) I | 0.0221114 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0220766 |
| CUL3 | cullin 3 | 0.0218887 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0218143 |
| JUN | jun proto-oncogene | 0.0216056 |
| STC2 | stanniocalcin 2 | 0.0215674 |
| DIAPH1 | diaphanous-related formin 1 | 0.0215477 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0213885 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0213037 |
| THOC2 | THO complex 2 | 0.0212646 |
| FERMT2 | fermitin family member 2 | 0.0211759 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0209861 |
| STK40 | serine/threonine kinase 40 | 0.0209185 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0205293 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.020522 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0204224 |
| MED13L | mediator complex subunit 13-like | 0.0204184 |
| FLNB | filamin B, beta | 0.0203938 |
| CA8 | carbonic anhydrase VIII | 0.0203537 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0203465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.220398 |
| RPS16 | ribosomal protein S16 | -0.209569 |
| VIM | vimentin | -0.208544 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165198 |
| AHNAK | AHNAK nucleoprotein | -0.133661 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0979478 |
| PTMA | prothymosin, alpha | -0.0914334 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0884135 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0877068 |
| FBL | fibrillarin | -0.0763778 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0763138 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.057107 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0558783 |
| SBF2 | SET binding factor 2 | -0.0480585 |
| AFAP1 | actin filament associated protein 1 | -0.0476132 |
| ATG7 | autophagy related 7 | -0.045593 |
| RPL35A | ribosomal protein L35a | -0.0452098 |
| S100A6 | S100 calcium binding protein A6 | -0.0449316 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0447613 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0439582 |
| RPLP1 | ribosomal protein, large, P1 | -0.0438816 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0427025 |
| RNF220 | ring finger protein 220 | -0.0421309 |
| MYOF | myoferlin | -0.04171 |
| RPLP2 | ribosomal protein, large, P2 | -0.041122 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0404028 |
| TMSB10 | thymosin beta 10 | -0.0395202 |
| DIAPH2 | diaphanous-related formin 2 | -0.0392847 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0392198 |
| EGFR | epidermal growth factor receptor | -0.0390231 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0370839 |
| RPS24 | ribosomal protein S24 | -0.035788 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0345159 |
| HM13 | histocompatibility (minor) 13 | -0.0340006 |
| CANX | calnexin | -0.0337131 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0329922 |
| PKM | pyruvate kinase, muscle | -0.0324664 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0322161 |
| PGK1 | phosphoglycerate kinase 1 | -0.0317328 |
| SEPTIN7 | septin 7 | -0.0306608 |
| ENO1 | enolase 1, (alpha) | -0.0302016 |
| CTSD | cathepsin D | -0.0286362 |
| RPS5 | ribosomal protein S5 | -0.0284008 |
| MAP4 | microtubule-associated protein 4 | -0.0278914 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0272724 |
| HMGA2 | high mobility group AT-hook 2 | -0.0272584 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0267156 |
| ZNF780B | zinc finger protein 780B | -0.0263961 |
| NHSL1 | NHS-like 1 | -0.0261949 |
| RPLP0 | ribosomal protein, large, P0 | -0.0260922 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0255158 |
| RPL11 | ribosomal protein L11 | -0.0250477 |
| FMNL2 | formin-like 2 | -0.0247252 |
| CD44 | CD44 molecule (Indian blood group) | -0.0243698 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0239773 |
| EHBP1 | EH domain binding protein 1 | -0.0239326 |
| BMERB1 | bMERB domain containing 1 | -0.0237871 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0233537 |
| RPS27A | ribosomal protein S27a | -0.0233081 |
| RPL12 | ribosomal protein L12 | -0.0232633 |
| HMGB1 | high mobility group box 1 | -0.0232391 |
| ZNF546 | zinc finger protein 546 | -0.0226584 |
| PRSS23 | protease, serine, 23 | -0.0224826 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0223469 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0222395 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0221656 |
| RPS25 | ribosomal protein S25 | -0.0215626 |
| RPL26 | ribosomal protein L26 | -0.0212329 |
| FTL | ferritin, light polypeptide | -0.0211145 |
| RPL27A | ribosomal protein L27a | -0.0209696 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0208246 |
| KRT19 | keratin 19, type I | -0.0207385 |
| CDCP1 | CUB domain containing protein 1 | -0.0204678 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0203666 |
| FBXO17 | F-box protein 17 | -0.0202598 |
| RPL8 | ribosomal protein L8 | -0.0201375 |
| RACK1 | receptor for activated C kinase 1 | -0.0201365 |
| RPS8 | ribosomal protein S8 | -0.0200078 |
| RPS21 | ribosomal protein S21 | -0.0197802 |
| GNAS | GNAS complex locus | -0.019778 |
| ACTG1 | actin gamma 1 | -0.019666 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0194938 |
| CAVIN1 | caveolae associated protein 1 | -0.0193034 |
| PFN1 | profilin 1 | -0.0191961 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0189168 |
| RPL34 | ribosomal protein L34 | -0.0188798 |
| CDK6 | cyclin-dependent kinase 6 | -0.0188796 |
| TNS3 | tensin 3 | -0.0187759 |
| TMEM123 | transmembrane protein 123 | -0.0187432 |
| CCND1 | cyclin D1 | -0.0186217 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0185069 |
| GOLGA4 | golgin A4 | -0.0185058 |
| RPS14 | ribosomal protein S14 | -0.0183957 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0183616 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0181931 |
| HMGA1 | high mobility group AT-hook 1 | -0.0181884 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0180366 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0180312 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0179299 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0177223 |