| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.0956696 |
| VEGFA | vascular endothelial growth factor A | 0.0771666 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0712889 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0701299 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0663715 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0624163 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0592837 |
| MSN | moesin | 0.0584899 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0558291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0524226 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0520584 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0515388 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.048254 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0472211 |
| NAV2 | neuron navigator 2 | 0.0469992 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0465648 |
| RUNX1 | runt-related transcription factor 1 | 0.0452073 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0450037 |
| COL5A3 | collagen, type V, alpha 3 | 0.0443522 |
| CLIC4 | chloride intracellular channel 4 | 0.0441546 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.043195 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0426474 |
| HDAC9 | histone deacetylase 9 | 0.0404594 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0395457 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0391416 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0388758 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0384916 |
| FAT1 | FAT atypical cadherin 1 | 0.0379741 |
| SVIL | supervillin | 0.0375212 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374727 |
| ZNF644 | zinc finger protein 644 | 0.036853 |
| TGM2 | transglutaminase 2 | 0.0358661 |
| NPTN | neuroplastin | 0.0357275 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0353349 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0351222 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0341621 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0335966 |
| CORO1C | coronin, actin binding protein, 1C | 0.0333614 |
| AFDN | afadin, adherens junction formation factor | 0.0331367 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0326334 |
| HPCAL1 | hippocalcin-like 1 | 0.0326142 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0326096 |
| CD44 | CD44 molecule (Indian blood group) | 0.0323531 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0323349 |
| SETD5 | SET domain containing 5 | 0.0317816 |
| SMC4 | structural maintenance of chromosomes 4 | 0.03133 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0312798 |
| MKI67 | marker of proliferation Ki-67 | 0.0306726 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0306018 |
| MED13L | mediator complex subunit 13-like | 0.0305137 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0300931 |
| RLIM | ring finger protein, LIM domain interacting | 0.0300359 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0297435 |
| CCNL1 | cyclin L1 | 0.0293579 |
| VCL | vinculin | 0.0292658 |
| RBM39 | RNA binding motif protein 39 | 0.0289897 |
| ACTN1 | actinin, alpha 1 | 0.0289155 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281566 |
| XPO1 | exportin 1 | 0.0281468 |
| CENPF | centromere protein F, 350/400kDa | 0.0279854 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0279686 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0279479 |
| APP | amyloid beta (A4) precursor protein | 0.0276137 |
| ANXA2 | annexin A2 | 0.0275546 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0275083 |
| ACTN4 | actinin, alpha 4 | 0.0271355 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.027098 |
| TPX2 | TPX2, microtubule-associated | 0.026471 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0264291 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0260808 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0260489 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0256326 |
| FERMT2 | fermitin family member 2 | 0.0255648 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0255455 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0253915 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0252646 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0249189 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0248535 |
| SEPTIN9 | septin 9 | 0.0248492 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.02481 |
| BRD2 | bromodomain containing 2 | 0.0247614 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0247333 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0246255 |
| SDC4 | syndecan 4 | 0.0242542 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0239777 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0235988 |
| PLEC | plectin | 0.0235071 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.02335 |
| ITGAV | integrin, alpha V | 0.0233449 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0232873 |
| LMO7 | LIM domain 7 | 0.0232613 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0232472 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0231159 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0230973 |
| FNIP1 | folliculin interacting protein 1 | 0.0230822 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0229836 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0229595 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0228539 |
| TOP1 | topoisomerase (DNA) I | 0.0227885 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0227797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.149178 |
| VIM | vimentin | -0.146922 |
| CDH13 | cadherin 13 | -0.122446 |
| FN1 | fibronectin 1 | -0.118601 |
| NDRG1 | N-myc downstream regulated 1 | -0.115999 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.111559 |
| STC1 | stanniocalcin 1 | -0.100433 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0999272 |
| B2M | beta-2-microglobulin | -0.0949446 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0932076 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0927438 |
| COL1A2 | collagen, type I, alpha 2 | -0.089555 |
| TMSB10 | thymosin beta 10 | -0.0887866 |
| MMP12 | matrix metallopeptidase 12 | -0.0868591 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0859833 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0839405 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0806423 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0788028 |
| FTL | ferritin, light polypeptide | -0.0766537 |
| IL1B | interleukin 1, beta | -0.0757394 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0737468 |
| HLA-A | major histocompatibility complex, class I, A | -0.0665103 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0609237 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0581306 |
| INHBA | inhibin, beta A | -0.0576061 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0574732 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0552599 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.054164 |
| HLA-B | major histocompatibility complex, class I, B | -0.0539727 |
| TPM4 | tropomyosin 4 | -0.050996 |
| RAI14 | retinoic acid induced 14 | -0.0494361 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0489815 |
| GLIS3 | GLIS family zinc finger 3 | -0.0486958 |
| CA12 | carbonic anhydrase XII | -0.0454647 |
| FRMD4A | FERM domain containing 4A | -0.0454605 |
| MTSS1 | metastasis suppressor 1 | -0.0454087 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0450223 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0442788 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0438561 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0432831 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0430272 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0426013 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.041263 |
| TPM1 | tropomyosin 1 (alpha) | -0.0406144 |
| HM13 | histocompatibility (minor) 13 | -0.0405724 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0402211 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0396581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0379525 |
| OXR1 | oxidation resistance 1 | -0.0377456 |
| GNAS | GNAS complex locus | -0.0376469 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0376199 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0371832 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353627 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0346008 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0345685 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0337951 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0337078 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0337045 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0336344 |
| ACTG1 | actin gamma 1 | -0.0334496 |
| CLMP | CXADR-like membrane protein | -0.0332301 |
| FBN1 | fibrillin 1 | -0.0332194 |
| RND3 | Rho family GTPase 3 | -0.0321651 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0318886 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0316539 |
| VCAN | versican | -0.0315965 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0315476 |
| POU2F2 | POU class 2 homeobox 2 | -0.0312526 |
| HLA-E | major histocompatibility complex, class I, E | -0.0307968 |
| PTMA | prothymosin, alpha | -0.0305892 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.0300921 |
| EGFR | epidermal growth factor receptor | -0.0295598 |
| BICC1 | BicC family RNA binding protein 1 | -0.0292302 |
| IER3 | immediate early response 3 | -0.0288653 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0287953 |
| FAM107B | family with sequence similarity 107, member B | -0.0287857 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0287276 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0286125 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0284714 |
| XAF1 | XIAP associated factor 1 | -0.0282947 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0282483 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0278319 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.027816 |
| NRP1 | neuropilin 1 | -0.0277145 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0276745 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.027665 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0275336 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0274053 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0273858 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.027082 |
| TNS3 | tensin 3 | -0.0270582 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0264454 |
| NREP | neuronal regeneration related protein | -0.0263398 |
| TWIST2 | twist family bHLH transcription factor 2 | -0.0262797 |
| CADM1 | cell adhesion molecule 1 | -0.0260091 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0256728 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0256221 |
| CST3 | cystatin C | -0.0255598 |
| CAVIN1 | caveolae associated protein 1 | -0.0253515 |
| S100A10 | S100 calcium binding protein A10 | -0.0251524 |
