| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.154036 |
| MCL1 | myeloid cell leukemia 1 | 0.0792727 |
| PDE10A | phosphodiesterase 10A | 0.076369 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0655942 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0634149 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.061211 |
| CHGB | chromogranin B | 0.0594815 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0545599 |
| ASPH | aspartate beta-hydroxylase | 0.0513485 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0498632 |
| VEGFA | vascular endothelial growth factor A | 0.0397389 |
| FAT1 | FAT atypical cadherin 1 | 0.03641 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0350322 |
| CPE | carboxypeptidase E | 0.0345484 |
| NDRG1 | N-myc downstream regulated 1 | 0.0343131 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0330109 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0321059 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0289442 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0289426 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0285172 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0272502 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0268989 |
| STC1 | stanniocalcin 1 | 0.0268274 |
| NBEA | neurobeachin | 0.0266175 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0265407 |
| PCM1 | pericentriolar material 1 | 0.0263647 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.025728 |
| TPM3 | tropomyosin 3 | 0.0256249 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0248371 |
| FAM13A | family with sequence similarity 13, member A | 0.024138 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0237249 |
| HYOU1 | hypoxia up-regulated 1 | 0.0233183 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0231716 |
| POTEF | POTE ankyrin domain family, member F | 0.0227338 |
| SVIL | supervillin | 0.0225903 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0225823 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0220886 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.02203 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0218588 |
| GRAMD4 | GRAM domain containing 4 | 0.0214105 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0214039 |
| EXT1 | exostosin glycosyltransferase 1 | 0.02114 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0207602 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0206368 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.020459 |
| SCG2 | secretogranin II | 0.0202898 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0202556 |
| EFNA5 | ephrin-A5 | 0.0199434 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0198609 |
| EZR | ezrin | 0.0194969 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0193833 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0193047 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0192165 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0191655 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0190464 |
| RPL3 | ribosomal protein L3 | 0.0187757 |
| PCBP2 | poly(rC) binding protein 2 | 0.0185738 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0183826 |
| SETX | senataxin | 0.0180775 |
| TMEM255B | transmembrane protein 255B | 0.0177149 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0175642 |
| ZNF292 | zinc finger protein 292 | 0.0175296 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0175124 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0171869 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0171171 |
| ZNF638 | zinc finger protein 638 | 0.0170514 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.016894 |
| MGA | MGA, MAX dimerization protein | 0.0167792 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0166453 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0165965 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.016582 |
| RUNX1 | runt-related transcription factor 1 | 0.0165721 |
| SIK2 | salt-inducible kinase 2 | 0.0163984 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0163681 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0163065 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0161934 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0161136 |
| FLNB | filamin B, beta | 0.0161122 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0161044 |
| DST | dystonin | 0.0160726 |
| MYO1B | myosin IB | 0.0160669 |
| NAV2 | neuron navigator 2 | 0.0160479 |
| MSN | moesin | 0.0160237 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0158544 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0158223 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0156746 |
| NCKAP5 | NCK-associated protein 5 | 0.0155166 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0154691 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0154435 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0153986 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0152694 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0152023 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0151895 |
| TUSC3 | tumor suppressor candidate 3 | 0.0151556 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0150299 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0147466 |
| SUCO | SUN domain containing ossification factor | 0.0143161 |
| DIDO1 | death inducer-obliterator 1 | 0.0143064 |
| NBAS | neuroblastoma amplified sequence | 0.0142469 |
| AHR | aryl hydrocarbon receptor | 0.0141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.13727 |
| SNTG1 | syntrophin, gamma 1 | -0.0775726 |
| CALCA | calcitonin-related polypeptide alpha | -0.0740094 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0592755 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0532952 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0530704 |
| TENM1 | teneurin transmembrane protein 1 | -0.0523373 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0469224 |
| SYT1 | synaptotagmin I | -0.0468464 |
| RPL26 | ribosomal protein L26 | -0.0458348 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0432094 |
| RPS21 | ribosomal protein S21 | -0.0425295 |
| FOXC1 | forkhead box C1 | -0.0407114 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0403327 |
| NRG1 | neuregulin 1 | -0.0399981 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0397195 |
| RPL11 | ribosomal protein L11 | -0.0378371 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0351261 |
| RPL37 | ribosomal protein L37 | -0.0336902 |
| RPS8 | ribosomal protein S8 | -0.0335881 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0335407 |
| TMSB10 | thymosin beta 10 | -0.0327447 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0326448 |
| RPS3 | ribosomal protein S3 | -0.0325354 |
| GNAS | GNAS complex locus | -0.0321701 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0307666 |
| RPL31 | ribosomal protein L31 | -0.0302955 |
| MT2A | metallothionein 2A | -0.030052 |
| GPC5 | glypican 5 | -0.0297379 |
| RPL37A | ribosomal protein L37a | -0.0296389 |
| RPS6 | ribosomal protein S6 | -0.0291437 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0287944 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0287199 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0283348 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280614 |
| RPL23 | ribosomal protein L23 | -0.0277042 |
| RPS24 | ribosomal protein S24 | -0.0273473 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271344 |
| FTL | ferritin, light polypeptide | -0.0269808 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0267396 |
| RPL34 | ribosomal protein L34 | -0.0262167 |
| RPS27A | ribosomal protein S27a | -0.0258876 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0255918 |
| PTCHD4 | patched domain containing 4 | -0.0252237 |
| S100A9 | S100 calcium binding protein A9 | -0.0248581 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0247195 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0246468 |
| UBB | ubiquitin B | -0.0245661 |
| RPL19 | ribosomal protein L19 | -0.0241172 |
| RPL6 | ribosomal protein L6 | -0.0238348 |
| FGF14 | fibroblast growth factor 14 | -0.0237858 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0237481 |
| RPS25 | ribosomal protein S25 | -0.0235304 |
| RBM25 | RNA binding motif protein 25 | -0.0234086 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0228692 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0225897 |
| RPLP0 | ribosomal protein, large, P0 | -0.0223104 |
| RPL36AL | ribosomal protein L36a-like | -0.0221867 |
| RACK1 | receptor for activated C kinase 1 | -0.0221729 |
| RPL36 | ribosomal protein L36 | -0.02213 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0218798 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0217123 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -0.0215876 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0215139 |
| RPL38 | ribosomal protein L38 | -0.0213254 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0212428 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0210131 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0208101 |
| RPL30 | ribosomal protein L30 | -0.0207124 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0204959 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0202223 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0200318 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.019877 |
| RPL36A | ribosomal protein L36a | -0.0197139 |
| RPL12 | ribosomal protein L12 | -0.0196434 |
| CENPF | centromere protein F, 350/400kDa | -0.0195861 |
| RPL35 | ribosomal protein L35 | -0.0195745 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0195649 |
| RPL5 | ribosomal protein L5 | -0.0194194 |
| HMGB2 | high mobility group box 2 | -0.0191443 |
| RPL32 | ribosomal protein L32 | -0.0190195 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0189131 |
| GPC6 | glypican 6 | -0.0189054 |
| RPS12 | ribosomal protein S12 | -0.0188959 |
| RPL35A | ribosomal protein L35a | -0.0187987 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0185398 |
| TPR | translocated promoter region, nuclear basket protein | -0.0184726 |
| FUS | FUS RNA binding protein | -0.0184044 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0183132 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0181763 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0179941 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0179391 |
| CCDC88A | coiled-coil domain containing 88A | -0.0178757 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0177617 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0177543 |
| RPS19 | ribosomal protein S19 | -0.0177153 |
| RPS5 | ribosomal protein S5 | -0.0176983 |
| NFIA | nuclear factor I/A | -0.017559 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0173457 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.017329 |
