Salicylic acid_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Salicylic acid perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Salicylic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0622776
ADAM10 ADAM metallopeptidase domain 10 0.0598048
ZNF292 zinc finger protein 292 0.0562632
RBM39 RNA binding motif protein 39 0.0551506
DSCAM Down syndrome cell adhesion molecule 0.0511878
FLNB filamin B, beta 0.050086
PICALM phosphatidylinositol binding clathrin assembly protein 0.0473383
ZCCHC7 zinc finger, CCHC domain containing 7 0.0454926
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0446514
BRWD1 bromodomain and WD repeat domain containing 1 0.0407058
ECT2 epithelial cell transforming 2 0.0406028
NBAS neuroblastoma amplified sequence 0.0405232
ZFAND3 zinc finger, AN1-type domain 3 0.0398518
GOLGA4 golgin A4 0.0396682
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0393863
SOX6 SRY (sex determining region Y)-box 6 0.0391682
SSBP2 single-stranded DNA binding protein 2 0.0380916
QKI QKI, KH domain containing, RNA binding 0.0374262
KDM3A lysine (K)-specific demethylase 3A 0.0369788
ZNF608 zinc finger protein 608 0.0366768
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0359773
CCNL1 cyclin L1 0.0347837
MSI2 musashi RNA-binding protein 2 0.0344926
ELOVL5 ELOVL fatty acid elongase 5 0.034171
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0335928
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0333041
TGFBR3 transforming growth factor, beta receptor III 0.0329606
MON2 MON2 homolog (S. cerevisiae) 0.0324711
RNF145 ring finger protein 145 0.0320241
KMT2E lysine (K)-specific methyltransferase 2E 0.0317223
ADAM9 ADAM metallopeptidase domain 9 0.031444
HDAC9 histone deacetylase 9 0.0313064
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0312566
XPO1 exportin 1 0.0311023
SAMD4A sterile alpha motif domain containing 4A 0.0306083
EIF4A2 eukaryotic translation initiation factor 4A2 0.0304198
ZNF638 zinc finger protein 638 0.030405
PTBP2 polypyrimidine tract binding protein 2 0.0303725
CDC73 cell division cycle 73 0.030264
TXNRD1 thioredoxin reductase 1 0.0299864
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0292657
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0288902
ZMYM2 zinc finger, MYM-type 2 0.0287022
TFG TRK-fused gene 0.0280901
CD47 CD47 molecule 0.0280819
COG5 component of oligomeric golgi complex 5 0.0277369
ANKRD11 ankyrin repeat domain 11 0.0277279
ANK2 ankyrin 2, neuronal 0.0275978
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.027001
TMF1 TATA element modulatory factor 1 0.02696
PYGB phosphorylase, glycogen; brain 0.0269129
NFIA nuclear factor I/A 0.0266868
MBD5 methyl-CpG binding domain protein 5 0.0265413
BIRC6 baculoviral IAP repeat containing 6 0.0264378
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0264191
TBC1D5 TBC1 domain family, member 5 0.0262768
KMT2C lysine (K)-specific methyltransferase 2C 0.0262737
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0259591
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0258088
RAB6A RAB6A, member RAS oncogene family 0.0256393
TMEM65 transmembrane protein 65 0.025207
LPP LIM domain containing preferred translocation partner in lipoma 0.0251133
COPA coatomer protein complex, subunit alpha 0.0249193
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0249042
NCKAP1 NCK-associated protein 1 0.0247806
NUP58 nucleoporin 58 0.0246577
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0246466
USP3 ubiquitin specific peptidase 3 0.0246054
SEC31A SEC31 homolog A (S. cerevisiae) 0.0245687
YEATS2 YEATS domain containing 2 0.0242711
TTC3 tetratricopeptide repeat domain 3 0.0242599
ZFC3H1 zinc finger, C3H1-type containing 0.0240202
DOCK3 dedicator of cytokinesis 3 0.0239213
SBF2 SET binding factor 2 0.0239075
ANKRD17 ankyrin repeat domain 17 0.0238453
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0237746
HELZ helicase with zinc finger 0.0235164
DENND5A DENN/MADD domain containing 5A 0.023361
ZNF148 zinc finger protein 148 0.0231645
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0230157
FNDC3B fibronectin type III domain containing 3B 0.0229916
CAMTA1 calmodulin binding transcription activator 1 0.0229324
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0227733
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0227038
TNRC6A trinucleotide repeat containing 6A 0.0226087
CHD7 chromodomain helicase DNA binding protein 7 0.0225701
OGA O-GlcNAcase 0.022493
TMEM41B transmembrane protein 41B 0.0223771
GARS1 glycyl-tRNA synthetase 1 0.0223576
SMYD3 SET and MYND domain containing 3 0.0222484
TRERF1 transcriptional regulating factor 1 0.0222421
PRELID2 PRELI domain containing 2 0.0221468
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.021909
USP24 ubiquitin specific peptidase 24 0.021861
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.02175
SRP54 signal recognition particle 54kDa 0.0216965
NAMPT nicotinamide phosphoribosyltransferase 0.021696
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0215987
FXR1 fragile X mental retardation, autosomal homolog 1 0.0213106
KDM6A lysine (K)-specific demethylase 6A 0.0210146

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.35045
PTMA prothymosin, alpha -0.336107
RPS6 ribosomal protein S6 -0.140411
RPS8 ribosomal protein S8 -0.125118
TPT1 tumor protein, translationally-controlled 1 -0.122436
BMP10 bone morphogenetic protein 10 -0.1171
RPL35A ribosomal protein L35a -0.0933998
PKM pyruvate kinase, muscle -0.0879842
ACTG1 actin gamma 1 -0.0847761
RPLP1 ribosomal protein, large, P1 -0.0846681
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0809287
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0769056
RPL34 ribosomal protein L34 -0.0756709
RPL26 ribosomal protein L26 -0.0726567
CCND1 cyclin D1 -0.0717086
RPL12 ribosomal protein L12 -0.0691636
RPL37A ribosomal protein L37a -0.0670864
RPL31 ribosomal protein L31 -0.0663714
ARL4C ADP-ribosylation factor-like 4C -0.0654968
VCL vinculin -0.0631134
RPS19 ribosomal protein S19 -0.0617077
RPL19 ribosomal protein L19 -0.0616982
RPL9 ribosomal protein L9 -0.0579493
RPS23 ribosomal protein S23 -0.05695
RPS13 ribosomal protein S13 -0.0556268
PDE4B phosphodiesterase 4B, cAMP-specific -0.0548564
RPL23 ribosomal protein L23 -0.0537163
HSPB1 heat shock 27kDa protein 1 -0.0535952
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0534476
TM4SF1 transmembrane 4 L six family member 1 -0.05257
RPS3 ribosomal protein S3 -0.0514098
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0500498
RPLP2 ribosomal protein, large, P2 -0.0488906
ENO1 enolase 1, (alpha) -0.0483033
RPS25 ribosomal protein S25 -0.0469569
RPS12 ribosomal protein S12 -0.0463198
RPL11 ribosomal protein L11 -0.0458838
S100A4 S100 calcium binding protein A4 -0.0449178
RPL36 ribosomal protein L36 -0.0445929
RPS27A ribosomal protein S27a -0.0441271
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0431523
RPL7A ribosomal protein L7a -0.0430007
RPS24 ribosomal protein S24 -0.0427843
S100A9 S100 calcium binding protein A9 -0.0427152
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0421257
RACK1 receptor for activated C kinase 1 -0.040971
RPLP0 ribosomal protein, large, P0 -0.0405196
RPL32 ribosomal protein L32 -0.0403978
TMSB10 thymosin beta 10 -0.0394449
S100A10 S100 calcium binding protein A10 -0.0383133
RPS16 ribosomal protein S16 -0.0382919
EGFR epidermal growth factor receptor -0.0373575
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0360477
RPL7 ribosomal protein L7 -0.0360416
RPS21 ribosomal protein S21 -0.0357865
RPS11 ribosomal protein S11 -0.0355364
RPS14 ribosomal protein S14 -0.0350145
RPL35 ribosomal protein L35 -0.0337006
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0335331
RPL37 ribosomal protein L37 -0.0335268
RPL8 ribosomal protein L8 -0.0325612
GLI3 GLI family zinc finger 3 -0.0322711
TPI1 triosephosphate isomerase 1 -0.0322647
RPS15 ribosomal protein S15 -0.0322528
NPAS2 neuronal PAS domain protein 2 -0.0321043
S100A6 S100 calcium binding protein A6 -0.0316804
RPL36A ribosomal protein L36a -0.0315713
RPS2 ribosomal protein S2 -0.0312788
EBNA1BP2 EBNA1 binding protein 2 -0.0312769
EIF1 eukaryotic translation initiation factor 1 -0.0309946
MYL12B myosin, light chain 12B, regulatory -0.0309656
RPS17 ribosomal protein S17 -0.0309468
MKI67 marker of proliferation Ki-67 -0.0308856
LOC102724023 ES1 protein homolog, mitochondrial -0.0306944
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0306439
RPL30 ribosomal protein L30 -0.0295135
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0293481
RPS27 ribosomal protein S27 -0.028823
PFN1 profilin 1 -0.0287125
RPL13A ribosomal protein L13a -0.028568
AHNAK AHNAK nucleoprotein -0.0284561
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0284165
TPM4 tropomyosin 4 -0.0284119
RPL18 ribosomal protein L18 -0.0283867
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0277671
RPS29 ribosomal protein S29 -0.027502
RPS10 ribosomal protein S10 -0.027447
HMGB1 high mobility group box 1 -0.0268455
RPL5 ribosomal protein L5 -0.0262455
KPNB1 karyopherin (importin) beta 1 -0.0259288
FOXP1 forkhead box P1 -0.0259225
RPL10A ribosomal protein L10a -0.0257985
RPL27A ribosomal protein L27a -0.0256818
SLC38A2 solute carrier family 38, member 2 -0.0255146
TUBA1B tubulin, alpha 1b -0.0254873
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0253608
TUBB4B tubulin, beta 4B class IVb -0.0251926
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0246135
RPS5 ribosomal protein S5 -0.0245589
EMP3 epithelial membrane protein 3 -0.0243659