| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Salicylic acid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Salicylic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.186449 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.145035 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.128026 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.12066 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.120255 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0848909 |
| NAV2 | neuron navigator 2 | 0.0748732 |
| ASPH | aspartate beta-hydroxylase | 0.0742991 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0695371 |
| HDAC9 | histone deacetylase 9 | 0.0673334 |
| MSN | moesin | 0.065747 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0653299 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0646112 |
| NDRG1 | N-myc downstream regulated 1 | 0.0643539 |
| CDH13 | cadherin 13 | 0.0604162 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0597636 |
| DUSP10 | dual specificity phosphatase 10 | 0.0554429 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0553814 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0553697 |
| PRELID2 | PRELI domain containing 2 | 0.0551632 |
| FNIP1 | folliculin interacting protein 1 | 0.0521298 |
| MYOF | myoferlin | 0.0516376 |
| COL5A1 | collagen, type V, alpha 1 | 0.0487139 |
| SEPTIN9 | septin 9 | 0.0486463 |
| INTS6 | integrator complex subunit 6 | 0.0480363 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0471322 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0454256 |
| TMEM132D | transmembrane protein 132D | 0.0451665 |
| RND3 | Rho family GTPase 3 | 0.0446399 |
| CCNL1 | cyclin L1 | 0.0413047 |
| PDE10A | phosphodiesterase 10A | 0.0411036 |
| BRD2 | bromodomain containing 2 | 0.0405415 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0403021 |
| FMNL2 | formin-like 2 | 0.0398864 |
| HMGA2 | high mobility group AT-hook 2 | 0.0387487 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0384788 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0383476 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0375253 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0371645 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0365508 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0358346 |
| RAD51B | RAD51 paralog B | 0.0357669 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0344882 |
| CEP250 | centrosomal protein 250kDa | 0.0340446 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0334402 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0332101 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0330722 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0323482 |
| PCBP3 | poly(rC) binding protein 3 | 0.0323091 |
| STC2 | stanniocalcin 2 | 0.031719 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0302988 |
| TNS3 | tensin 3 | 0.0299003 |
| EFNA5 | ephrin-A5 | 0.0295752 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0292336 |
| ARFGEF3 | ARFGEF family member 3 | 0.0290254 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0289684 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0289527 |
| TPM3 | tropomyosin 3 | 0.0288993 |
| WWOX | WW domain containing oxidoreductase | 0.0287434 |
| YEATS2 | YEATS domain containing 2 | 0.0286257 |
| EGFR | epidermal growth factor receptor | 0.0277865 |
| SQSTM1 | sequestosome 1 | 0.0277493 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0273089 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0272635 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0267595 |
| MCL1 | myeloid cell leukemia 1 | 0.0262145 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0261095 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0257536 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0250664 |
| MMP12 | matrix metallopeptidase 12 | 0.0249816 |
| FAM219A | family with sequence similarity 219, member A | 0.0249299 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0246969 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0246154 |
| DTNA | dystrobrevin, alpha | 0.0245461 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0244033 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0243352 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.023748 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0237461 |
| C3 | complement component 3 | 0.0235989 |
| ATXN1 | ataxin 1 | 0.0235135 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0234896 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0234274 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0232774 |
| ANXA1 | annexin A1 | 0.0231898 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0227394 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0226622 |
| ZNF638 | zinc finger protein 638 | 0.0224633 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224468 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0222894 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0221816 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0220704 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0220638 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0220048 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0218564 |
| LDHA | lactate dehydrogenase A | 0.0217686 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0217217 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0217172 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0216629 |
| EVC | Ellis van Creveld protein | 0.021601 |
| MLPH | melanophilin | 0.0215459 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244568 |
| VIM | vimentin | -0.20783 |
| FN1 | fibronectin 1 | -0.20079 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.136472 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.112067 |
| FRMD4A | FERM domain containing 4A | -0.111471 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.106522 |
| BICC1 | BicC family RNA binding protein 1 | -0.102153 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0940871 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0925647 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0923615 |
| GLIS3 | GLIS family zinc finger 3 | -0.0711501 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0686314 |
| THBS1 | thrombospondin 1 | -0.0659991 |
| ANXA2 | annexin A2 | -0.0659417 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0618512 |
| LOC112694756 | uncharaterized LOC112694756 | -0.05949 |
| FTL | ferritin, light polypeptide | -0.0587437 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0557321 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0544627 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0537706 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0536561 |
| TUBB | tubulin, beta class I | -0.0529893 |
| PGK1 | phosphoglycerate kinase 1 | -0.0517988 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0503629 |
| TMSB10 | thymosin beta 10 | -0.049493 |
| GNAS | GNAS complex locus | -0.0479443 |
| IER3 | immediate early response 3 | -0.0457481 |
| RPS24 | ribosomal protein S24 | -0.0444063 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0441616 |
| MKI67 | marker of proliferation Ki-67 | -0.0439312 |
| RPLP1 | ribosomal protein, large, P1 | -0.043865 |
| RTN4 | reticulon 4 | -0.0435532 |
| OSMR | oncostatin M receptor | -0.0432544 |
| UBC | ubiquitin C | -0.0431787 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0430666 |
| KLF6 | Kruppel-like factor 6 | -0.0427376 |
| CDCP1 | CUB domain containing protein 1 | -0.0425158 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0404679 |
| RPS6 | ribosomal protein S6 | -0.0401224 |
| RPL12 | ribosomal protein L12 | -0.0392036 |
| TNNC1 | troponin C type 1 (slow) | -0.0390437 |
| AHNAK | AHNAK nucleoprotein | -0.0380406 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0380174 |
| TXNRD1 | thioredoxin reductase 1 | -0.037857 |
| VCL | vinculin | -0.0378023 |
| HLA-E | major histocompatibility complex, class I, E | -0.0376457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0376047 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0365638 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0364609 |
| CD44 | CD44 molecule (Indian blood group) | -0.0364264 |
| ANLN | anillin, actin binding protein | -0.0361506 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0360904 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0357812 |
| RPL32 | ribosomal protein L32 | -0.0354887 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0353158 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0351244 |
| RPLP0 | ribosomal protein, large, P0 | -0.0345759 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0345143 |
| RPL35A | ribosomal protein L35a | -0.0343826 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0343188 |
| IL6 | interleukin 6 | -0.034124 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0338933 |
| HLA-B | major histocompatibility complex, class I, B | -0.0337288 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0336873 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0335154 |
| RPL19 | ribosomal protein L19 | -0.0334629 |
| SBF2 | SET binding factor 2 | -0.0334458 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0331942 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0321108 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0319541 |
| CDK17 | cyclin-dependent kinase 17 | -0.0318789 |
| PALLD | palladin, cytoskeletal associated protein | -0.0318197 |
| RUNX2 | runt-related transcription factor 2 | -0.0317402 |
| EHBP1 | EH domain binding protein 1 | -0.0314256 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0310766 |
| MAP4 | microtubule-associated protein 4 | -0.0307201 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0305823 |
| HDAC8 | histone deacetylase 8 | -0.0304773 |
| TKT | transketolase | -0.0303095 |
| RPL26 | ribosomal protein L26 | -0.0300569 |
| RPS8 | ribosomal protein S8 | -0.0299104 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0298315 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0298225 |
| FRMD5 | FERM domain containing 5 | -0.0288567 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0287415 |
| KYNU | kynureninase | -0.0287023 |
| PTMA | prothymosin, alpha | -0.0284156 |
| QKI | QKI, KH domain containing, RNA binding | -0.0283503 |
| RACK1 | receptor for activated C kinase 1 | -0.0283426 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0283052 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0276862 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0276629 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0273055 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0272099 |
| SRGN | serglycin | -0.0268792 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0264705 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0264119 |
| COL1A2 | collagen, type I, alpha 2 | -0.0258099 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0257915 |
