Salicylic acid_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Salicylic acid perturbation in SW 1088 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Salicylic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.203185
AHNAK AHNAK nucleoprotein 0.0867185
CDH13 cadherin 13 0.0854924
NRXN3 neurexin 3 0.0799685
TRIO trio Rho guanine nucleotide exchange factor 0.0756831
IGFBP3 insulin-like growth factor binding protein 3 0.0731179
ERRFI1 ERBB receptor feedback inhibitor 1 0.0658504
EXT1 exostosin glycosyltransferase 1 0.0635782
MYH9 myosin, heavy chain 9, non-muscle 0.0587036
TIMP3 TIMP metallopeptidase inhibitor 3 0.0581733
COL5A1 collagen, type V, alpha 1 0.0555365
EGFR epidermal growth factor receptor 0.0544639
KYNU kynureninase 0.0527813
VEGFC vascular endothelial growth factor C 0.0519427
FAM13A family with sequence similarity 13, member A 0.0491777
SAMD4A sterile alpha motif domain containing 4A 0.0467266
COL7A1 collagen, type VII, alpha 1 0.0458947
FN1 fibronectin 1 0.0456191
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0456189
VEGFA vascular endothelial growth factor A 0.0447704
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0440616
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0408065
TTC3 tetratricopeptide repeat domain 3 0.0405709
ZCCHC7 zinc finger, CCHC domain containing 7 0.0397701
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0390747
ANO6 anoctamin 6 0.0390491
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.038517
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0384124
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0383474
EXOC4 exocyst complex component 4 0.0377189
PDLIM5 PDZ and LIM domain 5 0.0372301
ATXN1 ataxin 1 0.0346646
MACF1 microtubule-actin crosslinking factor 1 0.033918
RUNX1 runt-related transcription factor 1 0.033243
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0326543
GLIS3 GLIS family zinc finger 3 0.0324118
ARB2A ARB2 cotranscriptional regulator A 0.0323027
KAZN kazrin, periplakin interacting protein 0.032236
TNS3 tensin 3 0.0315724
FAM20C family with sequence similarity 20, member C 0.0314097
PSD3 pleckstrin and Sec7 domain containing 3 0.0306966
FNDC3B fibronectin type III domain containing 3B 0.0300871
CXCL8 chemokine (C-X-C motif) ligand 8 0.0292582
CANX calnexin 0.0290922
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0290758
ZNF638 zinc finger protein 638 0.0290548
BBS9 Bardet-Biedl syndrome 9 0.0287278
LOX lysyl oxidase 0.0282341
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0282142
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0278435
EFNA5 ephrin-A5 0.027231
COPA coatomer protein complex, subunit alpha 0.0269843
ZBTB20 zinc finger and BTB domain containing 20 0.0269525
ANXA5 annexin A5 0.0257919
DNAH11 dynein, axonemal, heavy chain 11 0.0257847
PLEC plectin 0.0256267
PRELID2 PRELI domain containing 2 0.0252921
PTPRM protein tyrosine phosphatase, receptor type, M 0.0251482
INTS6 integrator complex subunit 6 0.0250926
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0249648
ACTN1 actinin, alpha 1 0.0247405
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0237279
SMAD3 SMAD family member 3 0.0236343
HDAC9 histone deacetylase 9 0.0234004
FNIP1 folliculin interacting protein 1 0.0231904
SEPTIN9 septin 9 0.0231792
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0230751
MMP12 matrix metallopeptidase 12 0.0228385
STC2 stanniocalcin 2 0.0225906
ZMIZ1 zinc finger, MIZ-type containing 1 0.0225731
FAM120B family with sequence similarity 120B 0.0224447
SDC4 syndecan 4 0.0224438
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0221612
KIRREL1 kirre like nephrin family adhesion molecule 1 0.0220678
ABLIM3 actin binding LIM protein family, member 3 0.0218966
ASPH aspartate beta-hydroxylase 0.0218769
DST dystonin 0.0218288
SOX5 SRY (sex determining region Y)-box 5 0.0218001
GYS1 glycogen synthase 1 (muscle) 0.0211347
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0210912
VCL vinculin 0.0209983
EHBP1 EH domain binding protein 1 0.0207837
LIMS1 LIM and senescent cell antigen-like domains 1 0.0207821
ARHGAP24 Rho GTPase activating protein 24 0.0206504
USP9X ubiquitin specific peptidase 9, X-linked 0.0200581
SETBP1 SET binding protein 1 0.0198751
AKAP9 A kinase (PRKA) anchor protein 9 0.0198673
STK10 serine/threonine kinase 10 0.0198478
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0197393
YME1L1 YME1-like 1 ATPase 0.019721
BACE2 beta-site APP-cleaving enzyme 2 0.0197121
LHFPL2 lipoma HMGIC fusion partner-like 2 0.019695
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0196843
TSC22D2 TSC22 domain family, member 2 0.0195529
FHIT fragile histidine triad 0.0195436
KDM4C lysine (K)-specific demethylase 4C 0.0194246
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.0193721
HIP1 huntingtin interacting protein 1 0.019317
IGF2 insulin-like growth factor 2 0.0192922
IL6 interleukin 6 0.0192465

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.319225
MT2A metallothionein 2A -0.286445
B2M beta-2-microglobulin -0.160911
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.160233
TMSB10 thymosin beta 10 -0.145932
VIM vimentin -0.138578
PTMA prothymosin, alpha -0.116519
HLA-B major histocompatibility complex, class I, B -0.0924863
MT1X metallothionein 1X -0.0713366
IGFBP7 insulin-like growth factor binding protein 7 -0.0684893
FTL ferritin, light polypeptide -0.0681647
RPL11 ribosomal protein L11 -0.0643819
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0637087
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0634385
ANLN anillin, actin binding protein -0.0570197
EIF1 eukaryotic translation initiation factor 1 -0.0567269
PDIA3 protein disulfide isomerase family A, member 3 -0.0550916
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0517246
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0514532
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0511587
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0511207
H3-3B H3.3 histone B -0.0508238
COL1A2 collagen, type I, alpha 2 -0.046865
RPS8 ribosomal protein S8 -0.0459872
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0455558
PTN pleiotrophin -0.0427508
HLA-A major histocompatibility complex, class I, A -0.0421523
ELL2 elongation factor, RNA polymerase II, 2 -0.0412325
TPT1 tumor protein, translationally-controlled 1 -0.0406215
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.039393
TGFBI transforming growth factor, beta-induced, 68kDa -0.0392662
LOC112694756 uncharaterized LOC112694756 -0.0388711
S100A6 S100 calcium binding protein A6 -0.0387055
PKM pyruvate kinase, muscle -0.0380067
CD44 CD44 molecule (Indian blood group) -0.0375117
POTEF POTE ankyrin domain family, member F -0.0373755
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0370077
MKI67 marker of proliferation Ki-67 -0.0368636
RPL34 ribosomal protein L34 -0.0358225
RPL35A ribosomal protein L35a -0.034899
S100A10 S100 calcium binding protein A10 -0.0348075
RPLP1 ribosomal protein, large, P1 -0.0347414
PFN1 profilin 1 -0.0341566
MAP1B microtubule-associated protein 1B -0.0338248
GNAS GNAS complex locus -0.0336991
CXCL3 chemokine (C-X-C motif) ligand 3 -0.0336694
S100A9 S100 calcium binding protein A9 -0.0334987
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0332649
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0331935
BSG basigin (Ok blood group) -0.0324164
MTPN myotrophin -0.0323932
RTN4 reticulon 4 -0.0323191
RPS6 ribosomal protein S6 -0.0322082
RPL12 ribosomal protein L12 -0.0318604
SEPTIN7 septin 7 -0.0316712
RPS2 ribosomal protein S2 -0.0307202
KMT2E lysine (K)-specific methyltransferase 2E -0.0304583
HMGB1 high mobility group box 1 -0.030114
ZNF292 zinc finger protein 292 -0.0300921
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0297143
TFG TRK-fused gene -0.0295855
STC1 stanniocalcin 1 -0.02955
HMGB2 high mobility group box 2 -0.0293543
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.029046
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.028788
RPL19 ribosomal protein L19 -0.0286899
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0282626
MATR3 matrin 3 -0.0282419
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0279775
TUBA1B tubulin, alpha 1b -0.0277842
RPS24 ribosomal protein S24 -0.0272783
TPX2 TPX2, microtubule-associated -0.0269339
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.02658
LAMB1 laminin, beta 1 -0.0264306
RPS5 ribosomal protein S5 -0.0263728
CKAP2 cytoskeleton associated protein 2 -0.0262525
RPS23 ribosomal protein S23 -0.0259117
GOLGA4 golgin A4 -0.0258995
ACTG1 actin gamma 1 -0.0257218
RPL15 ribosomal protein L15 -0.0256716
RPLP2 ribosomal protein, large, P2 -0.0253174
CCDC88A coiled-coil domain containing 88A -0.025314
RACK1 receptor for activated C kinase 1 -0.0252277
HLA-C major histocompatibility complex, class I, C -0.0251814
SETD5 SET domain containing 5 -0.0251522
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0250152
RPL31 ribosomal protein L31 -0.0248831
PPME1 protein phosphatase methylesterase 1 -0.0247992
SRSF11 serine/arginine-rich splicing factor 11 -0.0247579
EGR1 early growth response 1 -0.0246678
SUB1 SUB1 homolog (S. cerevisiae) -0.0245916
ANKRD17 ankyrin repeat domain 17 -0.0241282
RPL26 ribosomal protein L26 -0.0241189
VEZT vezatin, adherens junctions transmembrane protein -0.0241115
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0239934
SCAF11 SR-related CTD-associated factor 11 -0.0239169
CST3 cystatin C -0.0238866
RPL7 ribosomal protein L7 -0.0238724
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.023818
ATP5F1E ATP synthase F1 subunit epsilon -0.023746