Salicylic acid_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Salicylic acid perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Salicylic acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
CAPRIN2 caprin family member 2 0.0691896
ANXA1 annexin A1 0.0673556
BIRC3 baculoviral IAP repeat containing 3 0.0636028
ANXA2 annexin A2 0.057599
FMNL2 formin-like 2 0.0517933
SMAD3 SMAD family member 3 0.050129
APLP2 amyloid beta (A4) precursor-like protein 2 0.047478
GIGYF2 GRB10 interacting GYF protein 2 0.0466242
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0448564
BRD2 bromodomain containing 2 0.0433324
CEP250 centrosomal protein 250kDa 0.0429699
MTREX Mtr4 exosome RNA helicase 0.0411324
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0399891
EEF2 eukaryotic translation elongation factor 2 0.0399569
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0381433
MYH9 myosin, heavy chain 9, non-muscle 0.037655
POTEF POTE ankyrin domain family, member F 0.0374063
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0371091
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.03673
YPEL5 yippee-like 5 (Drosophila) 0.0357787
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0354661
DGKD diacylglycerol kinase, delta 130kDa 0.034532
GLS2 glutaminase 2 (liver, mitochondrial) 0.0344986
MSN moesin 0.0343015
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0339624
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0338631
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0337583
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0336334
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0335903
KDM6A lysine (K)-specific demethylase 6A 0.0332733
MATR3 matrin 3 0.0328674
CCNL1 cyclin L1 0.0328622
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0327277
JMJD1C jumonji domain containing 1C 0.0325828
BPTF bromodomain PHD finger transcription factor 0.0312923
IFRD1 interferon-related developmental regulator 1 0.0308772
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.0305973
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0302799
DIAPH1 diaphanous-related formin 1 0.0299148
TCP1 t-complex 1 0.0289395
PTK2 protein tyrosine kinase 2 0.0285976
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0285221
KDM2A lysine (K)-specific demethylase 2A 0.0282995
SDC4 syndecan 4 0.0280324
HILPDA hypoxia inducible lipid droplet-associated 0.0280096
HELZ helicase with zinc finger 0.0279144
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0278411
OXSR1 oxidative stress responsive 1 0.0275876
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.0273606
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0273293
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0271612
TBC1D23 TBC1 domain family, member 23 0.0267888
RICTOR RPTOR independent companion of MTOR, complex 2 0.0267216
TNIP1 TNFAIP3 interacting protein 1 0.026529
RND3 Rho family GTPase 3 0.026491
JUN jun proto-oncogene 0.0260855
DSCAM Down syndrome cell adhesion molecule 0.0259248
IRAK2 interleukin-1 receptor-associated kinase 2 0.0258583
SAMD4A sterile alpha motif domain containing 4A 0.0256988
PEAK1 pseudopodium-enriched atypical kinase 1 0.0256022
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0255532
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0255495
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0250961
YTHDC1 YTH domain containing 1 0.0249988
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.0248638
GATAD2B GATA zinc finger domain containing 2B 0.0248068
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0244132
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.0243705
ZNF292 zinc finger protein 292 0.0242972
PBX3 pre-B-cell leukemia homeobox 3 0.0242776
FUBP1 far upstream element (FUSE) binding protein 1 0.0242586
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.0241937
RAD23B RAD23 homolog B (S. cerevisiae) 0.0241509
PCLO piccolo presynaptic cytomatrix protein 0.0238758
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0235863
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0235535
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.0234654
CEP295 centrosomal protein 295kDa 0.0233179
EMP1 epithelial membrane protein 1 0.0232691
CYTH1 cytohesin 1 0.0232214
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0232046
USP9X ubiquitin specific peptidase 9, X-linked 0.0231186
ATP13A3 ATPase type 13A3 0.0231107
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 0.0230149
CSPP1 centrosome and spindle pole associated protein 1 0.022948
CSNK1A1 casein kinase 1, alpha 1 0.0227389
CORO1C coronin, actin binding protein, 1C 0.0227227
MSI2 musashi RNA-binding protein 2 0.0226584
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0223084
RCOR1 REST corepressor 1 0.0222509
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0221536
HBP1 HMG-box transcription factor 1 0.022149
NIBAN2 niban apoptosis regulator 2 0.0221105
SIN3A SIN3 transcription regulator family member A 0.0220024
ARF4 ADP-ribosylation factor 4 0.0219199
NFE2L1 nuclear factor, erythroid 2-like 1 0.0218348
ZCCHC7 zinc finger, CCHC domain containing 7 0.0217822
NPTN neuroplastin 0.0217735
SETD5 SET domain containing 5 0.0217335
PER1 period circadian clock 1 0.021731

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.191558
TPT1 tumor protein, translationally-controlled 1 -0.125085
SMYD3 SET and MYND domain containing 3 -0.08876
ATM ATM serine/threonine kinase -0.0747831
GOLGA4 golgin A4 -0.0716053
HMGA2 high mobility group AT-hook 2 -0.0688574
TAS2R14 taste receptor, type 2, member 14 -0.0683455
OSMR oncostatin M receptor -0.0609533
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0606749
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0594864
PTMA prothymosin, alpha -0.05877
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0580137
SLC38A2 solute carrier family 38, member 2 -0.0561929
CENPF centromere protein F, 350/400kDa -0.0555329
IGF2 insulin-like growth factor 2 -0.0551471
DPYD dihydropyrimidine dehydrogenase -0.0550462
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0546387
IARS1 isoleucyl-tRNA synthetase 1 -0.0537254
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.052151
AEBP2 AE binding protein 2 -0.052094
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0515736
FMN1 formin 1 -0.049427
ATG7 autophagy related 7 -0.0490525
BCAS3 breast carcinoma amplified sequence 3 -0.0489798
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0486361
APOLD1 apolipoprotein L domain containing 1 -0.0484604
FBXL7 F-box and leucine-rich repeat protein 7 -0.0483524
MON2 MON2 homolog (S. cerevisiae) -0.0479614
ZBTB20 zinc finger and BTB domain containing 20 -0.04677
RDX radixin -0.0464022
TM4SF1 transmembrane 4 L six family member 1 -0.0457993
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0453901
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0453581
PHF3 PHD finger protein 3 -0.044702
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0443589
MBD5 methyl-CpG binding domain protein 5 -0.0430035
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0425496
LDHA lactate dehydrogenase A -0.0424758
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0424573
TPX2 TPX2, microtubule-associated -0.0416338
CANX calnexin -0.0412433
FBXO11 F-box protein 11 -0.0411491
ANGPTL4 angiopoietin-like 4 -0.0405459
DNAAF9 dynein axonemal assembly factor 9 -0.0400113
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0399392
ANKRD12 ankyrin repeat domain 12 -0.0395661
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0384786
TBC1D5 TBC1 domain family, member 5 -0.0384682
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0383728
AKAP9 A kinase (PRKA) anchor protein 9 -0.0383174
CD44 CD44 molecule (Indian blood group) -0.0381194
CCDC88A coiled-coil domain containing 88A -0.0372149
CKAP2 cytoskeleton associated protein 2 -0.0371403
DNER delta/notch-like EGF repeat containing -0.0371075
IGFBP3 insulin-like growth factor binding protein 3 -0.0369529
NCOR1 nuclear receptor corepressor 1 -0.0367577
CCDC138 coiled-coil domain containing 138 -0.0367092
GPATCH8 G patch domain containing 8 -0.0366467
PDCD6IP programmed cell death 6 interacting protein -0.0362823
ANLN anillin, actin binding protein -0.0362785
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0360919
NBEAL1 neurobeachin-like 1 -0.0358833
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0357417
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0354095
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0352169
EXOC4 exocyst complex component 4 -0.0349487
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0344362
BABAM2 BRISC and BRCA1 A complex member 2 -0.0340043
SMC4 structural maintenance of chromosomes 4 -0.0337046
PCED1B PC-esterase domain containing 1B -0.033694
SNX14 sorting nexin 14 -0.0334177
CCNH cyclin H -0.0332671
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0330944
ZEB1 zinc finger E-box binding homeobox 1 -0.0327019
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0325344
DEK DEK proto-oncogene -0.0324571
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0324047
UGCG UDP-glucose ceramide glucosyltransferase -0.0322589
KIAA1328 KIAA1328 -0.0320015
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0316844
IL6ST interleukin 6 signal transducer -0.0316216
ARHGAP5 Rho GTPase activating protein 5 -0.0315813
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0315375
AHNAK AHNAK nucleoprotein -0.0314649
GOLGB1 golgin B1 -0.0314304
C6ORF62 chromosome 6 open reading frame 62 -0.0313809
PCNX4 pecanex 4 -0.0312928
DENND5B DENN/MADD domain containing 5B -0.0312578
NIPBL Nipped-B homolog (Drosophila) -0.0308841
GNAS GNAS complex locus -0.0306927
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0305066
KIF4A kinesin family member 4A -0.0304319
RSF1 remodeling and spacing factor 1 -0.0303363
RPL26 ribosomal protein L26 -0.0302527
LCORL ligand dependent nuclear receptor corepressor-like -0.0302468
NT5E 5'-nucleotidase, ecto (CD73) -0.0301958
BTG1 B-cell translocation gene 1, anti-proliferative -0.0299986
CLTC clathrin, heavy chain (Hc) -0.0299405
SPDL1 spindle apparatus coiled-coil protein 1 -0.0295468
ARID1B AT rich interactive domain 1B (SWI1-like) -0.0295214