Salicylic acid_SW1417 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Salicylic acid perturbation in SW1417 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Salicylic acid_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0713189
HSPA8 heat shock 70kDa protein 8 0.0540742
PLEC plectin 0.0532008
INTS6 integrator complex subunit 6 0.0521451
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0454002
APLP2 amyloid beta (A4) precursor-like protein 2 0.0449812
EXT1 exostosin glycosyltransferase 1 0.0440896
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0437649
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0432812
FAT1 FAT atypical cadherin 1 0.0420794
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0413977
CEMIP2 cell migration inducing hyaluronidase 2 0.0410022
MYH9 myosin, heavy chain 9, non-muscle 0.040843
CTBP2 C-terminal binding protein 2 0.0394613
USP9X ubiquitin specific peptidase 9, X-linked 0.0393536
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.0393223
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0387006
FNDC3B fibronectin type III domain containing 3B 0.0381037
SND1 staphylococcal nuclease and tudor domain containing 1 0.0375117
CEMIP cell migration inducing protein, hyaluronan binding 0.0375067
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0371399
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0364536
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0363554
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0363224
EPS8 epidermal growth factor receptor pathway substrate 8 0.0362367
KMT2C lysine (K)-specific methyltransferase 2C 0.0355475
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0342151
DSPP dentin sialophosphoprotein 0.0342112
SAMD4A sterile alpha motif domain containing 4A 0.034211
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0338863
GOLGB1 golgin B1 0.0337538
HDLBP high density lipoprotein binding protein 0.0337047
SMAD3 SMAD family member 3 0.0330337
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0318637
ZSWIM6 zinc finger, SWIM-type containing 6 0.0313989
HYOU1 hypoxia up-regulated 1 0.0307556
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0304372
AKAP13 A kinase (PRKA) anchor protein 13 0.0303211
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0296159
NCOA3 nuclear receptor coactivator 3 0.0295156
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0292363
COG5 component of oligomeric golgi complex 5 0.0290019
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0287092
CUL3 cullin 3 0.0287086
BIRC6 baculoviral IAP repeat containing 6 0.0282895
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0282354
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0275666
EIF4A2 eukaryotic translation initiation factor 4A2 0.027534
YAP1 Yes-associated protein 1 0.0269013
FAM107B family with sequence similarity 107, member B 0.0261384
MED13L mediator complex subunit 13-like 0.0257243
PDLIM5 PDZ and LIM domain 5 0.0250942
AHCYL2 adenosylhomocysteinase-like 2 0.0248876
CANX calnexin 0.0244307
TUFT1 tuftelin 1 0.0238175
TMF1 TATA element modulatory factor 1 0.0237804
PDIA5 protein disulfide isomerase family A, member 5 0.0237657
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0232478
ANKRD11 ankyrin repeat domain 11 0.0231829
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0230341
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.0229222
IFRD1 interferon-related developmental regulator 1 0.0228744
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0228595
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0223472
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0223333
EEF1G eukaryotic translation elongation factor 1 gamma 0.0223104
SHB Src homology 2 domain containing adaptor protein B 0.0221054
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 0.0219914
TTC3 tetratricopeptide repeat domain 3 0.0219301
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0218836
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0214099
AFDN afadin, adherens junction formation factor 0.0214076
GIGYF2 GRB10 interacting GYF protein 2 0.0213563
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0212822
ARHGAP26 Rho GTPase activating protein 26 0.0209514
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0206937
NEBL nebulette 0.0206781
SUCO SUN domain containing ossification factor 0.0203704
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0203129
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0201262
PTK2 protein tyrosine kinase 2 0.02004
COG6 component of oligomeric golgi complex 6 0.019995
ZFAND3 zinc finger, AN1-type domain 3 0.0195591
ZNF638 zinc finger protein 638 0.0195082
KDM4C lysine (K)-specific demethylase 4C 0.0194233
TRIP12 thyroid hormone receptor interactor 12 0.0192598
PTGES2 prostaglandin E synthase 2 0.0191582
HKDC1 hexokinase domain containing 1 0.0191536
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.0191274
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0190873
USP47 ubiquitin specific peptidase 47 0.0190059
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0189834
TLN1 talin 1 0.0189383
ADAM19 ADAM metallopeptidase domain 19 0.0188532
NBAS neuroblastoma amplified sequence 0.0187476
OSBPL10 oxysterol binding protein-like 10 0.0186674
RBM39 RNA binding motif protein 39 0.0186233
FMNL2 formin-like 2 0.0185774
EGFR epidermal growth factor receptor 0.0185553
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.0185068

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.212951
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.160056
FTL ferritin, light polypeptide -0.1456
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.138977
TMSB10 thymosin beta 10 -0.1299
MACC1 metastasis associated in colon cancer 1 -0.110349
LOC102724023 ES1 protein homolog, mitochondrial -0.105167
RPS21 ribosomal protein S21 -0.0917455
TPT1 tumor protein, translationally-controlled 1 -0.0759159
RPL12 ribosomal protein L12 -0.0730079
RPL35A ribosomal protein L35a -0.0724287
KRT18 keratin 18, type I -0.0718348
B2M beta-2-microglobulin -0.0684178
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0665898
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0659563
PERP PERP, TP53 apoptosis effector -0.0614929
S100A6 S100 calcium binding protein A6 -0.0598215
RPLP1 ribosomal protein, large, P1 -0.0583804
ZMYND8 zinc finger, MYND-type containing 8 -0.0575365
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.056089
RPLP0 ribosomal protein, large, P0 -0.0560587
CBX3 chromobox homolog 3 -0.0557114
EIF1 eukaryotic translation initiation factor 1 -0.0535318
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0532663
CCND1 cyclin D1 -0.0529612
EGR1 early growth response 1 -0.0524674
RPS6 ribosomal protein S6 -0.0516812
RPL18 ribosomal protein L18 -0.051612
BCL2L1 BCL2-like 1 -0.0514226
RPS24 ribosomal protein S24 -0.0503027
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0500954
CST3 cystatin C -0.0484591
TMEM123 transmembrane protein 123 -0.0481365
EPCAM epithelial cell adhesion molecule -0.0480121
S100A10 S100 calcium binding protein A10 -0.0470883
KRT19 keratin 19, type I -0.0469871
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0460881
RPS13 ribosomal protein S13 -0.0458972
KRT8 keratin 8, type II -0.0453257
RPL32 ribosomal protein L32 -0.04529
SOX4 SRY (sex determining region Y)-box 4 -0.0452395
MYL12B myosin, light chain 12B, regulatory -0.0447242
GSTP1 glutathione S-transferase pi 1 -0.0445497
IFITM1 interferon induced transmembrane protein 1 -0.0432599
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0425615
HMGA1 high mobility group AT-hook 1 -0.0424352
RPL8 ribosomal protein L8 -0.0420806
H1-0 H1.0 linker histone -0.041502
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0410757
RPL23 ribosomal protein L23 -0.0401874
SLC38A1 solute carrier family 38, member 1 -0.0397391
RPS8 ribosomal protein S8 -0.0393466
TMSB4X thymosin beta 4, X-linked -0.0391794
MAML2 mastermind-like 2 (Drosophila) -0.0390258
SNX9 sorting nexin 9 -0.0388442
RAB7A RAB7A, member RAS oncogene family -0.0383289
DEK DEK proto-oncogene -0.0381888
RPLP2 ribosomal protein, large, P2 -0.0381549
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0379427
HLA-A major histocompatibility complex, class I, A -0.0374222
MKI67 marker of proliferation Ki-67 -0.0368454
RPL36A ribosomal protein L36a -0.0350555
SMC4 structural maintenance of chromosomes 4 -0.0349235
RPS5 ribosomal protein S5 -0.0347831
MX2 MX dynamin-like GTPase 2 -0.0345329
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0343338
RPL34 ribosomal protein L34 -0.0343249
IFIH1 interferon induced with helicase C domain 1 -0.0343128
EDN1 endothelin 1 -0.0336911
FTH1 ferritin, heavy polypeptide 1 -0.0335733
RPL28 ribosomal protein L28 -0.0329056
RPS25 ribosomal protein S25 -0.0328277
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0328245
RPS19 ribosomal protein S19 -0.032594
CLDN4 claudin 4 -0.0322164
RPL26 ribosomal protein L26 -0.0321403
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.031884
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0318603
EHBP1 EH domain binding protein 1 -0.0317574
ADNP activity-dependent neuroprotector homeobox -0.0312916
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0312678
RPL31 ribosomal protein L31 -0.0312065
FRMD5 FERM domain containing 5 -0.0312029
ATP5F1E ATP synthase F1 subunit epsilon -0.0308056
MYOF myoferlin -0.0307048
RPL15 ribosomal protein L15 -0.0304604
RPL11 ribosomal protein L11 -0.0303381
IFI6 interferon, alpha-inducible protein 6 -0.0299921
THOC2 THO complex 2 -0.0296834
IER3 immediate early response 3 -0.0289158
PLAUR plasminogen activator, urokinase receptor -0.0289042
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0288044
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -0.0287531
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0287481
PLSCR1 phospholipid scramblase 1 -0.0286911
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0286703
GNAS GNAS complex locus -0.0283813
RPS14 ribosomal protein S14 -0.0283327
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0281835
KLF6 Kruppel-like factor 6 -0.0281582