Salicylic acid_SW48 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Salicylic acid perturbation in SW48 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Salicylic acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.166416
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.114802
RCOR1 REST corepressor 1 0.0869181
FHIT fragile histidine triad 0.0773238
HILPDA hypoxia inducible lipid droplet-associated 0.0632462
HMGA2 high mobility group AT-hook 2 0.0628182
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0602289
NDRG1 N-myc downstream regulated 1 0.0580257
ACTG1 actin gamma 1 0.0570375
CCSER1 coiled-coil serine-rich protein 1 0.0541791
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0528311
SNX9 sorting nexin 9 0.0514294
HSPA8 heat shock 70kDa protein 8 0.0512154
CPOX coproporphyrinogen oxidase 0.0505789
MYO5B myosin VB 0.0483418
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0461123
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0453458
PRELID2 PRELI domain containing 2 0.0446412
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0436587
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0427284
ZSWIM6 zinc finger, SWIM-type containing 6 0.0418855
ANXA1 annexin A1 0.0414566
FRAS1 Fraser extracellular matrix complex subunit 1 0.0408998
PARD3 par-3 family cell polarity regulator 0.0406665
USP9X ubiquitin specific peptidase 9, X-linked 0.0397942
AKAP13 A kinase (PRKA) anchor protein 13 0.0385543
LDHA lactate dehydrogenase A 0.0380683
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0379093
NUP50 nucleoporin 50kDa 0.0376737
FNDC3B fibronectin type III domain containing 3B 0.0375812
AKAP12 A kinase (PRKA) anchor protein 12 0.0370369
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0363183
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0363026
ATXN1 ataxin 1 0.0361345
JARID2 jumonji, AT rich interactive domain 2 0.0360486
ITGA6 integrin, alpha 6 0.0358167
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0353236
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0345914
MACF1 microtubule-actin crosslinking factor 1 0.0341668
MYH9 myosin, heavy chain 9, non-muscle 0.0328789
EEF2 eukaryotic translation elongation factor 2 0.0324267
EFNB2 ephrin-B2 0.0323652
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0310141
IGSF9B immunoglobulin superfamily, member 9B 0.030982
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0307408
HDAC4 histone deacetylase 4 0.0307128
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0306615
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0303286
TTC3 tetratricopeptide repeat domain 3 0.0302504
CREB5 cAMP responsive element binding protein 5 0.0300362
EZR ezrin 0.0299204
RAD51B RAD51 paralog B 0.0299069
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0296728
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0290802
EXOC4 exocyst complex component 4 0.0284656
HOMER1 homer scaffolding protein 1 0.0280545
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0278936
VMP1 vacuole membrane protein 1 0.0278188
IGFBP3 insulin-like growth factor binding protein 3 0.0277886
SAMD4A sterile alpha motif domain containing 4A 0.026871
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0268495
POTEF POTE ankyrin domain family, member F 0.0263779
OSBPL10 oxysterol binding protein-like 10 0.0261775
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0259346
EXT1 exostosin glycosyltransferase 1 0.0259072
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0258989
RPL3 ribosomal protein L3 0.0258367
VEGFA vascular endothelial growth factor A 0.025799
UBAP2 ubiquitin associated protein 2 0.0251561
WWOX WW domain containing oxidoreductase 0.0250856
INTS6 integrator complex subunit 6 0.025034
APLP2 amyloid beta (A4) precursor-like protein 2 0.0244122
PTPRG protein tyrosine phosphatase, receptor type, G 0.0243824
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0242857
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0242333
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0241773
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0241105
MYO1B myosin IB 0.0241053
SPTBN1 spectrin, beta, non-erythrocytic 1 0.024092
RRM2 ribonucleotide reductase M2 0.0238806
DDIT4 DNA-damage-inducible transcript 4 0.0238455
PSAT1 phosphoserine aminotransferase 1 0.0238329
BRD2 bromodomain containing 2 0.0237988
ASPH aspartate beta-hydroxylase 0.0237464
RASAL2 RAS protein activator like 2 0.0232834
TSC22D2 TSC22 domain family, member 2 0.0229768
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0228158
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0227306
LGALS12 lectin, galactoside-binding, soluble, 12 0.0225815
ZNRF3 zinc and ring finger 3 0.0224775
FAT1 FAT atypical cadherin 1 0.0224161
NHSL1 NHS-like 1 0.022395
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0219807
SPATS2L spermatogenesis associated, serine-rich 2-like 0.021335
FAM120A family with sequence similarity 120A 0.0213264
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough 0.0211709
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0211292
NCAPG2 non-SMC condensin II complex, subunit G2 0.021117
FMNL2 formin-like 2 0.0210099
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0207278

decreased expression

Symbol Name Standardized Value
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.225038
LMO7 LIM domain 7 -0.117788
OXR1 oxidation resistance 1 -0.0798304
RPS24 ribosomal protein S24 -0.0792157
TXNRD1 thioredoxin reductase 1 -0.0695765
NCEH1 neutral cholesterol ester hydrolase 1 -0.0669808
GOLGA4 golgin A4 -0.059388
RAB10 RAB10, member RAS oncogene family -0.0567939
RPL26 ribosomal protein L26 -0.0543716
ITPKC inositol-trisphosphate 3-kinase C -0.0534415
SERINC5 serine incorporator 5 -0.0532175
RPS6 ribosomal protein S6 -0.0528559
EIF1 eukaryotic translation initiation factor 1 -0.0527111
MTAP methylthioadenosine phosphorylase -0.0520076
TMSB10 thymosin beta 10 -0.0515521
RBM25 RNA binding motif protein 25 -0.050845
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0501533
RPL11 ribosomal protein L11 -0.049164
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0491217
CD36 CD36 molecule (thrombospondin receptor) -0.0476353
EVA1C eva-1 homolog C (C. elegans) -0.0470893
TPT1 tumor protein, translationally-controlled 1 -0.0467181
RPL12 ribosomal protein L12 -0.0465604
RUNX2 runt-related transcription factor 2 -0.0456848
RPLP1 ribosomal protein, large, P1 -0.0452902
RPL35A ribosomal protein L35a -0.0446396
TOP1 topoisomerase (DNA) I -0.0436029
LOC102724023 ES1 protein homolog, mitochondrial -0.0433161
RPS8 ribosomal protein S8 -0.0433045
HDAC2 histone deacetylase 2 -0.0432501
RPLP0 ribosomal protein, large, P0 -0.042959
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0419817
PLAUR plasminogen activator, urokinase receptor -0.0417674
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0394237
RPL32 ribosomal protein L32 -0.0382727
RPL34 ribosomal protein L34 -0.038222
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0378038
NAP1L1 nucleosome assembly protein 1-like 1 -0.0369143
RSL1D1 ribosomal L1 domain containing 1 -0.0365808
NEMF nuclear export mediator factor -0.0364847
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0351471
RPS19 ribosomal protein S19 -0.0349533
ITFG1 integrin alpha FG-GAP repeat containing 1 -0.0348599
RPL36A ribosomal protein L36a -0.034413
ITPRID2 ITPR interacting domain containing 2 -0.0343816
RNF43 ring finger protein 43 -0.0322322
NCOR1 nuclear receptor corepressor 1 -0.031531
VCL vinculin -0.0311538
RPS4X ribosomal protein S4, X-linked -0.0306116
RPL31 ribosomal protein L31 -0.0299746
RPL36 ribosomal protein L36 -0.0290744
RPL19 ribosomal protein L19 -0.0289365
RPS3 ribosomal protein S3 -0.0282983
FOXO1 forkhead box O1 -0.0273948
RPL23 ribosomal protein L23 -0.0273562
LAMC2 laminin, gamma 2 -0.027277
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.0270948
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.0267294
ZMYM2 zinc finger, MYM-type 2 -0.0259785
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.0255662
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0253784
USP6NL USP6 N-terminal like -0.0252691
RPS28 ribosomal protein S28 -0.025191
RPLP2 ribosomal protein, large, P2 -0.0250619
RPS2 ribosomal protein S2 -0.0249797
RPL30 ribosomal protein L30 -0.0245782
ADGRA3 adhesion G protein-coupled receptor A3 -0.0243927
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0243016
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -0.024179
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0241366
KLF6 Kruppel-like factor 6 -0.0240093
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0232895
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0231326
KDM3A lysine (K)-specific demethylase 3A -0.0229423
CLASP2 cytoplasmic linker associated protein 2 -0.0228959
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0226849
AREG amphiregulin -0.0225878
PRRC2C proline-rich coiled-coil 2C -0.0225805
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0224392
TUT4 terminal uridylyl transferase 4 -0.0222439
PDE4B phosphodiesterase 4B, cAMP-specific -0.0220699
YBX3 Y box binding protein 3 -0.0217531
SLC38A1 solute carrier family 38, member 1 -0.021701
RPL9 ribosomal protein L9 -0.021491
TCERG1 transcription elongation regulator 1 -0.0214376
NF1 neurofibromin 1 -0.0213536
ANXA3 annexin A3 -0.0212716
RPL13A ribosomal protein L13a -0.0211405
FNDC3A fibronectin type III domain containing 3A -0.0210865
AVL9 AVL9 homolog (S. cerevisiase) -0.0210177
SGPP2 sphingosine-1-phosphate phosphatase 2 -0.0210173
MYOF myoferlin -0.0209641
OGA O-GlcNAcase -0.0208959
NFXL1 nuclear transcription factor, X-box binding-like 1 -0.0208379
ARL5B ADP-ribosylation factor-like 5B -0.0207769
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0206905
RPS15 ribosomal protein S15 -0.0205763
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0205746
STRN3 striatin, calmodulin binding protein 3 -0.0205455
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0204307