| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sapanisertib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sapanisertib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0998941 |
| RPS12 | ribosomal protein S12 | 0.0927408 |
| RPL37A | ribosomal protein L37a | 0.0810385 |
| RPS19 | ribosomal protein S19 | 0.0763654 |
| RPL35A | ribosomal protein L35a | 0.0687954 |
| RPL36 | ribosomal protein L36 | 0.0672299 |
| RPS3 | ribosomal protein S3 | 0.0669809 |
| RPS8 | ribosomal protein S8 | 0.0647564 |
| RPL26 | ribosomal protein L26 | 0.0611272 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0604101 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0597964 |
| RPL12 | ribosomal protein L12 | 0.0590925 |
| RPL31 | ribosomal protein L31 | 0.0562662 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0498431 |
| RUNX1 | runt-related transcription factor 1 | 0.049643 |
| RPLP2 | ribosomal protein, large, P2 | 0.0443272 |
| CMIP | c-Maf inducing protein | 0.0422183 |
| RPS6 | ribosomal protein S6 | 0.0412866 |
| RPS27 | ribosomal protein S27 | 0.037818 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0371519 |
| RACK1 | receptor for activated C kinase 1 | 0.0369615 |
| CADM2 | cell adhesion molecule 2 | 0.0350039 |
| RPL27 | ribosomal protein L27 | 0.0341787 |
| RPS27A | ribosomal protein S27a | 0.0332481 |
| RPL23 | ribosomal protein L23 | 0.0328724 |
| RPS17 | ribosomal protein S17 | 0.0321201 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0320372 |
| RPL18 | ribosomal protein L18 | 0.0318781 |
| RPL35 | ribosomal protein L35 | 0.0316683 |
| RPL36A | ribosomal protein L36a | 0.0315661 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0303487 |
| RPS13 | ribosomal protein S13 | 0.0293094 |
| RPLP1 | ribosomal protein, large, P1 | 0.0280376 |
| RPL38 | ribosomal protein L38 | 0.0277453 |
| RPS10 | ribosomal protein S10 | 0.0273873 |
| GPHN | gephyrin | 0.0267599 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.025747 |
| RPS4X | ribosomal protein S4, X-linked | 0.0255505 |
| RPS29 | ribosomal protein S29 | 0.0249999 |
| RPL28 | ribosomal protein L28 | 0.0244157 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0243488 |
| RPL34 | ribosomal protein L34 | 0.0242103 |
| RPL37 | ribosomal protein L37 | 0.0239338 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0237544 |
| RPL9 | ribosomal protein L9 | 0.0232319 |
| RPS25 | ribosomal protein S25 | 0.0230904 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0225269 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0224614 |
| RPS16 | ribosomal protein S16 | 0.0223902 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0222107 |
| PODXL | podocalyxin-like | 0.0219148 |
| RPL27A | ribosomal protein L27a | 0.0215152 |
| RPS14 | ribosomal protein S14 | 0.0213896 |
| ARFGEF3 | ARFGEF family member 3 | 0.0207962 |
| RPL5 | ribosomal protein L5 | 0.0203055 |
| RPL19 | ribosomal protein L19 | 0.0201281 |
| RPS2 | ribosomal protein S2 | 0.0198642 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0198408 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0195061 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0194883 |
| AREG | amphiregulin | 0.0194851 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0194552 |
| SEC24A | SEC24 family member A | 0.0193144 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0187069 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0183613 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0183394 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0183191 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0176877 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0176393 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0175923 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0175531 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0175024 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0172306 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0168149 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0167802 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0165177 |
| RPS21 | ribosomal protein S21 | 0.0161815 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0154605 |
| RPS28 | ribosomal protein S28 | 0.0152812 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0152703 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0147071 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0146646 |
| RPL10A | ribosomal protein L10a | 0.0146181 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0143752 |
| RPL13A | ribosomal protein L13a | 0.0143568 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0142133 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.014201 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0141238 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0140325 |
| PDE10A | phosphodiesterase 10A | 0.0138668 |
| ANK2 | ankyrin 2, neuronal | 0.0138622 |
| RPS20 | ribosomal protein S20 | 0.0138165 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0136767 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0136699 |
| RPL7A | ribosomal protein L7a | 0.0136032 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0135079 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0132073 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0131814 |
| RPS7 | ribosomal protein S7 | 0.0130637 |
| RPS24 | ribosomal protein S24 | 0.0128652 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295399 |
| VIM | vimentin | -0.196927 |
| PTMA | prothymosin, alpha | -0.164722 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.161635 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113227 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0851144 |
| TMSB4X | thymosin beta 4, X-linked | -0.0778715 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0734578 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0638309 |
| CENPF | centromere protein F, 350/400kDa | -0.0602034 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.059913 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0585971 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0580703 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0569655 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0566868 |
| SPAG9 | sperm associated antigen 9 | -0.0514195 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0506572 |
| EZR | ezrin | -0.0488111 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0472622 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.046424 |
| TXNIP | thioredoxin interacting protein | -0.0455389 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0442045 |
| POTEF | POTE ankyrin domain family, member F | -0.0436859 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0420451 |
| JMJD1C | jumonji domain containing 1C | -0.0415387 |
| SEPTIN7 | septin 7 | -0.0414584 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0412074 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0409339 |
| ACTG1 | actin gamma 1 | -0.0407077 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0402952 |
| XPO1 | exportin 1 | -0.0398 |
| OGA | O-GlcNAcase | -0.0395459 |
| KLF6 | Kruppel-like factor 6 | -0.0388294 |
| UBC | ubiquitin C | -0.0384668 |
| SRGN | serglycin | -0.0379708 |
| AHNAK | AHNAK nucleoprotein | -0.0371279 |
| ANXA1 | annexin A1 | -0.0363779 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0354047 |
| MKI67 | marker of proliferation Ki-67 | -0.0347828 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0346524 |
| TOP1 | topoisomerase (DNA) I | -0.0346007 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0342963 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0338333 |
| WASF2 | WAS protein family, member 2 | -0.0335397 |
| KLHL24 | kelch-like family member 24 | -0.0329905 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0322499 |
| DEK | DEK proto-oncogene | -0.0321074 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0311406 |
| ANLN | anillin, actin binding protein | -0.0307891 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0305969 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0305265 |
| S100A10 | S100 calcium binding protein A10 | -0.0304091 |
| MYOF | myoferlin | -0.0299127 |
| PHIP | pleckstrin homology domain interacting protein | -0.0298859 |
| GLG1 | golgi glycoprotein 1 | -0.0295593 |
| TMEM123 | transmembrane protein 123 | -0.0294809 |
| SBF2 | SET binding factor 2 | -0.0294339 |
| TPR | translocated promoter region, nuclear basket protein | -0.0290573 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0290332 |
| ZNF217 | zinc finger protein 217 | -0.0290018 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.028772 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0287487 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0287141 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0284487 |
| RBM39 | RNA binding motif protein 39 | -0.028422 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281626 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.028142 |
| CANX | calnexin | -0.0279887 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0279193 |
| WDR45B | WD repeat domain 45B | -0.0273444 |
| ZNF292 | zinc finger protein 292 | -0.0273029 |
| MATR3 | matrin 3 | -0.0272718 |
| H1-0 | H1.0 linker histone | -0.0272193 |
| ECT2 | epithelial cell transforming 2 | -0.0272018 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0271142 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0268259 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0267498 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0266912 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0266594 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0266322 |
| CD44 | CD44 molecule (Indian blood group) | -0.026459 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0264482 |
| ATXN2 | ataxin 2 | -0.0262473 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0259821 |
| RTN4 | reticulon 4 | -0.0258724 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0257406 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0256851 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.025621 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0256 |
| TMSB10 | thymosin beta 10 | -0.0255958 |
| ERBIN | erbb2 interacting protein | -0.025332 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0253047 |
| FMNL2 | formin-like 2 | -0.0251633 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.025055 |
| ADAR | adenosine deaminase, RNA-specific | -0.0249163 |
| RAI1 | retinoic acid induced 1 | -0.0248729 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0247507 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0243787 |
| SRPK2 | SRSF protein kinase 2 | -0.0243025 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0242528 |
