| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.15723 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0886592 |
| CD44 | CD44 molecule (Indian blood group) | 0.0879364 |
| VIM | vimentin | 0.0715205 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0671239 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.057696 |
| PRELID2 | PRELI domain containing 2 | 0.0562902 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0541413 |
| VCL | vinculin | 0.0526053 |
| LDHA | lactate dehydrogenase A | 0.0500991 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0493555 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0482107 |
| HDAC9 | histone deacetylase 9 | 0.0472682 |
| GLIS3 | GLIS family zinc finger 3 | 0.0460523 |
| ERBIN | erbb2 interacting protein | 0.0458117 |
| EFNA5 | ephrin-A5 | 0.0453902 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0450702 |
| NAV2 | neuron navigator 2 | 0.0447939 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0436841 |
| EXT1 | exostosin glycosyltransferase 1 | 0.043439 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.042784 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0426994 |
| EGFR | epidermal growth factor receptor | 0.042394 |
| DST | dystonin | 0.0419499 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0414634 |
| STC1 | stanniocalcin 1 | 0.0407588 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0406971 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0400246 |
| NEK7 | NIMA-related kinase 7 | 0.0393706 |
| SMYD3 | SET and MYND domain containing 3 | 0.0383186 |
| CALR | calreticulin | 0.0372655 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0365785 |
| ASPH | aspartate beta-hydroxylase | 0.03608 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0359338 |
| RASA2 | RAS p21 protein activator 2 | 0.0354728 |
| ATXN1 | ataxin 1 | 0.0347759 |
| PTK2 | protein tyrosine kinase 2 | 0.0346216 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0339039 |
| MB21D2 | Mab-21 domain containing 2 | 0.0335621 |
| CDH13 | cadherin 13 | 0.0335378 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.033186 |
| RPS3 | ribosomal protein S3 | 0.0329704 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.032683 |
| RASAL2 | RAS protein activator like 2 | 0.0320063 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0319005 |
| RUNX1 | runt-related transcription factor 1 | 0.0317716 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0315525 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.031355 |
| FLNB | filamin B, beta | 0.0310813 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0302764 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0296989 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0294194 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0291684 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0290112 |
| EHBP1 | EH domain binding protein 1 | 0.028753 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.028556 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0283434 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0280314 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0278695 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0278617 |
| DNMBP | dynamin binding protein | 0.0278198 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0278168 |
| SP100 | SP100 nuclear antigen | 0.0277231 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0274293 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0268899 |
| SVIL | supervillin | 0.0267454 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0265793 |
| INTS6 | integrator complex subunit 6 | 0.026519 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0264848 |
| PARD3 | par-3 family cell polarity regulator | 0.0263357 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.026123 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0258184 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0257496 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0257487 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0257248 |
| NAV1 | neuron navigator 1 | 0.0257134 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0255767 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025262 |
| KLF6 | Kruppel-like factor 6 | 0.0250704 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0242799 |
| RRM2 | ribonucleotide reductase M2 | 0.0242582 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0242566 |
| SMAD3 | SMAD family member 3 | 0.0241274 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0235732 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0235652 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0234375 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0233548 |
| MYO9A | myosin IXA | 0.0232225 |
| SBF2 | SET binding factor 2 | 0.023173 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0230869 |
| CDK13 | cyclin-dependent kinase 13 | 0.0229548 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0227498 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0226311 |
| APP | amyloid beta (A4) precursor protein | 0.0226229 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0226102 |
| MYOF | myoferlin | 0.0222734 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0219725 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0218514 |
| JMJD1C | jumonji domain containing 1C | 0.021849 |
| DUSP6 | dual specificity phosphatase 6 | 0.0218002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.313405 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.265414 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129559 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.10674 |
| FN1 | fibronectin 1 | -0.100868 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0991354 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0845102 |
| SUCNR1 | succinate receptor 1 | -0.0832344 |
| MAP1B | microtubule-associated protein 1B | -0.0701911 |
| POTEF | POTE ankyrin domain family, member F | -0.0695863 |
| TMSB10 | thymosin beta 10 | -0.0688049 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.06227 |
| S100A10 | S100 calcium binding protein A10 | -0.0600909 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0544031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0534456 |
| COL1A2 | collagen, type I, alpha 2 | -0.0533157 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0532876 |
| COL5A1 | collagen, type V, alpha 1 | -0.0528192 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.051917 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.050275 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0492768 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0489077 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0488106 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0486924 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0476897 |
| THBS2 | thrombospondin 2 | -0.04675 |
| CSTB | cystatin B (stefin B) | -0.0452942 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0424474 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0420065 |
| KRT81 | keratin 81, type II | -0.0414268 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0397412 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0396185 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0374765 |
| LRRC17 | leucine rich repeat containing 17 | -0.0374069 |
| IL7R | interleukin 7 receptor | -0.0372156 |
| LMNA | lamin A/C | -0.0371941 |
| GOLGA4 | golgin A4 | -0.0359415 |
| COL1A1 | collagen, type I, alpha 1 | -0.0351576 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0342663 |
| CD99 | CD99 molecule | -0.033796 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.033581 |
| FOSL1 | FOS-like antigen 1 | -0.0328573 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0326357 |
| CANX | calnexin | -0.0316515 |
| MEIS2 | Meis homeobox 2 | -0.031282 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0311535 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0304413 |
| LAMB1 | laminin, beta 1 | -0.0298564 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0293874 |
| MSI2 | musashi RNA-binding protein 2 | -0.0292527 |
| TPM4 | tropomyosin 4 | -0.0289731 |
| DCLK2 | doublecortin-like kinase 2 | -0.027958 |
| COL5A2 | collagen, type V, alpha 2 | -0.0278925 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0276843 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0273941 |
| COL3A1 | collagen, type III, alpha 1 | -0.0273033 |
| TAGLN2 | transgelin 2 | -0.0271827 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0269105 |
| TUBB | tubulin, beta class I | -0.026821 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0265821 |
| GOLGB1 | golgin B1 | -0.0265634 |
| CCND1 | cyclin D1 | -0.0264456 |
| RPL35A | ribosomal protein L35a | -0.0259748 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0253234 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0249126 |
| HLA-B | major histocompatibility complex, class I, B | -0.0248009 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0244361 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244102 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0242707 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0240611 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0238508 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0234739 |
| LOX | lysyl oxidase | -0.0233423 |
| RRBP1 | ribosome binding protein 1 | -0.0229043 |
| HLA-C | major histocompatibility complex, class I, C | -0.0228735 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0226031 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0225019 |
| LOXL2 | lysyl oxidase-like 2 | -0.022133 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0220894 |
| KIF5B | kinesin family member 5B | -0.0220775 |
| PTMA | prothymosin, alpha | -0.0219203 |
| PRSS23 | protease, serine, 23 | -0.0216999 |
| PLAT | plasminogen activator, tissue | -0.0213015 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0212619 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0211567 |
| MX2 | MX dynamin-like GTPase 2 | -0.0208019 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0206122 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0204089 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0200974 |
| TPM1 | tropomyosin 1 (alpha) | -0.0200493 |
| S100A9 | S100 calcium binding protein A9 | -0.0199455 |
| TGFB1 | transforming growth factor, beta 1 | -0.0197206 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0196166 |
| GLG1 | golgi glycoprotein 1 | -0.0193242 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0190037 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0190036 |
| CALU | calumenin | -0.0183611 |
| ACTG1 | actin gamma 1 | -0.0180776 |
| ADM | adrenomedullin | -0.0178187 |
| PODXL | podocalyxin-like | -0.017334 |
