| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.165315 |
| MTSS1 | metastasis suppressor 1 | 0.15038 |
| MEF2A | myocyte enhancer factor 2A | 0.134353 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.104901 |
| LMO7 | LIM domain 7 | 0.100675 |
| HLA-E | major histocompatibility complex, class I, E | 0.0974558 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0906369 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0904324 |
| MYOF | myoferlin | 0.0882428 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0861468 |
| RAI14 | retinoic acid induced 14 | 0.0844551 |
| ANXA1 | annexin A1 | 0.080881 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0778441 |
| NDRG1 | N-myc downstream regulated 1 | 0.0743755 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0710281 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0677875 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0652995 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0632775 |
| PGK1 | phosphoglycerate kinase 1 | 0.0628132 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0607701 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0562133 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0534434 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0520247 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.051957 |
| B2M | beta-2-microglobulin | 0.0508825 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0500005 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0486158 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0478707 |
| PTK2 | protein tyrosine kinase 2 | 0.0465657 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0463437 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.0449274 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0444551 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0442655 |
| EMP1 | epithelial membrane protein 1 | 0.0440839 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0430463 |
| EZR | ezrin | 0.0425002 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.041217 |
| CD44 | CD44 molecule (Indian blood group) | 0.0410629 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0410261 |
| EFNA5 | ephrin-A5 | 0.0408532 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.040263 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0393591 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0389361 |
| FAM107B | family with sequence similarity 107, member B | 0.0381009 |
| LDHA | lactate dehydrogenase A | 0.0374256 |
| UBC | ubiquitin C | 0.0370366 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0365513 |
| DOK5 | docking protein 5 | 0.035953 |
| SPAG9 | sperm associated antigen 9 | 0.0358988 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0354037 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0349997 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0349959 |
| CD9 | CD9 molecule | 0.0348758 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0347283 |
| PRRC1 | proline-rich coiled-coil 1 | 0.034329 |
| SMYD3 | SET and MYND domain containing 3 | 0.034207 |
| SBF2 | SET binding factor 2 | 0.0341585 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0338012 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0336273 |
| JMJD1C | jumonji domain containing 1C | 0.0334617 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0333604 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0333508 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0331017 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0330239 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0330029 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.032628 |
| DUSP6 | dual specificity phosphatase 6 | 0.0323196 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0322458 |
| NF1 | neurofibromin 1 | 0.0320741 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0320318 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0318527 |
| SGMS2 | sphingomyelin synthase 2 | 0.0314398 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0313358 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0312897 |
| ENO1 | enolase 1, (alpha) | 0.0310701 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0308609 |
| NEK7 | NIMA-related kinase 7 | 0.0308022 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0307225 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0306887 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0302473 |
| GOLGB1 | golgin B1 | 0.0302329 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0297892 |
| LAMC2 | laminin, gamma 2 | 0.0294753 |
| CALU | calumenin | 0.029333 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0291756 |
| TJP1 | tight junction protein 1 | 0.0290359 |
| LDAF1 | lipid droplet assembly factor 1 | 0.0290259 |
| MYADM | myeloid-associated differentiation marker | 0.0288274 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0287995 |
| ADAR | adenosine deaminase, RNA-specific | 0.0282019 |
| OXR1 | oxidation resistance 1 | 0.0281545 |
| KIAA1217 | KIAA1217 | 0.0280568 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0279137 |
| COG5 | component of oligomeric golgi complex 5 | 0.0279077 |
| TMEM245 | transmembrane protein 245 | 0.0278987 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0278023 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0274876 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0274491 |
| MT1E | metallothionein 1E | 0.0268111 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0267882 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.17346 |
| TMSB10 | thymosin beta 10 | -0.169905 |
| RPS21 | ribosomal protein S21 | -0.112855 |
| POTEF | POTE ankyrin domain family, member F | -0.0853953 |
| RPLP2 | ribosomal protein, large, P2 | -0.0814868 |
| PLAT | plasminogen activator, tissue | -0.0720724 |
| MT2A | metallothionein 2A | -0.0616678 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0579969 |
| S100A2 | S100 calcium binding protein A2 | -0.0553637 |
| RPS19 | ribosomal protein S19 | -0.054457 |
| GNAS | GNAS complex locus | -0.0540926 |
| RPL37A | ribosomal protein L37a | -0.0512026 |
| RPS23 | ribosomal protein S23 | -0.0507918 |
| PODXL | podocalyxin-like | -0.0495662 |
| PRELID2 | PRELI domain containing 2 | -0.0475356 |
| RPLP1 | ribosomal protein, large, P1 | -0.0469129 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0456898 |
| RPL36 | ribosomal protein L36 | -0.045156 |
| LAMA5 | laminin, alpha 5 | -0.0437532 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0434855 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0421145 |
| PKM | pyruvate kinase, muscle | -0.0419744 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0413638 |
| KRT17 | keratin 17, type I | -0.0407824 |
| RPL28 | ribosomal protein L28 | -0.0402721 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0399986 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0389896 |
| CLIC4 | chloride intracellular channel 4 | -0.0384991 |
| ANLN | anillin, actin binding protein | -0.0381216 |
| ADIRF | adipogenesis regulatory factor | -0.037774 |
| BCL2L1 | BCL2-like 1 | -0.0374317 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0363864 |
| IER3 | immediate early response 3 | -0.0362992 |
| RPL9 | ribosomal protein L9 | -0.0360921 |
| RPL35 | ribosomal protein L35 | -0.0359138 |
| PTMA | prothymosin, alpha | -0.0358829 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0350684 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.034836 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0343939 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.0342341 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0340271 |
| RPS6 | ribosomal protein S6 | -0.0337675 |
| RPL8 | ribosomal protein L8 | -0.0331795 |
| IGF2 | insulin-like growth factor 2 | -0.0326273 |
| JAG1 | jagged 1 | -0.0325181 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0325136 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0323679 |
| SULF2 | sulfatase 2 | -0.0319021 |
| INTS6 | integrator complex subunit 6 | -0.0317213 |
| RPL19 | ribosomal protein L19 | -0.0312494 |
| ACTN4 | actinin, alpha 4 | -0.0310054 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0305581 |
| S100A6 | S100 calcium binding protein A6 | -0.0305195 |
| VCL | vinculin | -0.0300929 |
| FOSL1 | FOS-like antigen 1 | -0.0300806 |
| RPL35A | ribosomal protein L35a | -0.0300744 |
| ASPH | aspartate beta-hydroxylase | -0.0296428 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0293282 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0292258 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0290579 |
| AHNAK | AHNAK nucleoprotein | -0.0289435 |
| EFHD2 | EF-hand domain family, member D2 | -0.0288403 |
| RPL32 | ribosomal protein L32 | -0.0287582 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0286586 |
| RPS15 | ribosomal protein S15 | -0.0283677 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0283459 |
| PLEC | plectin | -0.0283141 |
| MT1G | metallothionein 1G | -0.0279273 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0278734 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.027861 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0275095 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0273705 |
| S100A10 | S100 calcium binding protein A10 | -0.0272565 |
| EPHA2 | EPH receptor A2 | -0.0270535 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0269075 |
| SULF1 | sulfatase 1 | -0.0268138 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0267618 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0266977 |
| S100A9 | S100 calcium binding protein A9 | -0.0266222 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0265239 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0264213 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0263428 |
| RPS27 | ribosomal protein S27 | -0.0258723 |
| SEC61G | Sec61 gamma subunit | -0.0254804 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.025243 |
| CDK6 | cyclin-dependent kinase 6 | -0.0250469 |
| PRDX1 | peroxiredoxin 1 | -0.0249353 |
| RPL23 | ribosomal protein L23 | -0.0247647 |
| GUK1 | guanylate kinase 1 | -0.0247629 |
| CCDC34 | coiled-coil domain containing 34 | -0.0247254 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0247037 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0243556 |
| RSF1 | remodeling and spacing factor 1 | -0.0242587 |
| KRT8 | keratin 8, type II | -0.0241008 |
| HMGA2 | high mobility group AT-hook 2 | -0.0240557 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0239953 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0238264 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0237383 |
| TOP1 | topoisomerase (DNA) I | -0.0236425 |
| ANKRD12 | ankyrin repeat domain 12 | -0.023642 |
