| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.154292 |
| B2M | beta-2-microglobulin | 0.0859947 |
| SLTM | SAFB-like, transcription modulator | 0.0778692 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0723407 |
| KRT17 | keratin 17, type I | 0.0699256 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0691442 |
| LMO7 | LIM domain 7 | 0.0668723 |
| LAMB3 | laminin, beta 3 | 0.0665432 |
| EGFR | epidermal growth factor receptor | 0.0641945 |
| TXNRD1 | thioredoxin reductase 1 | 0.0640473 |
| LAMA4 | laminin, alpha 4 | 0.0603385 |
| OGA | O-GlcNAcase | 0.0602021 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0557752 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0556253 |
| KYNU | kynureninase | 0.054539 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0512525 |
| ASPH | aspartate beta-hydroxylase | 0.0505747 |
| EZR | ezrin | 0.0488309 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0481224 |
| TXNIP | thioredoxin interacting protein | 0.0477681 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0472828 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0439988 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0428855 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0421337 |
| HMGA2 | high mobility group AT-hook 2 | 0.0420211 |
| CLTC | clathrin, heavy chain (Hc) | 0.0418362 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0415794 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.041372 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0412557 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0408051 |
| FAM13A | family with sequence similarity 13, member A | 0.0407775 |
| NRG1 | neuregulin 1 | 0.0407377 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.040709 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0406438 |
| RAD51B | RAD51 paralog B | 0.0398558 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0397355 |
| FRMD5 | FERM domain containing 5 | 0.0394063 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0378756 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0374981 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0367481 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0367261 |
| CCNI | cyclin I | 0.0365946 |
| ENO1 | enolase 1, (alpha) | 0.0363774 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0360189 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0360077 |
| FMNL2 | formin-like 2 | 0.03569 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0352859 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0352469 |
| OSMR | oncostatin M receptor | 0.0352338 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0348293 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0344953 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0341147 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0336957 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0329549 |
| TPR | translocated promoter region, nuclear basket protein | 0.032525 |
| RUNX1 | runt-related transcription factor 1 | 0.032293 |
| PCBP2 | poly(rC) binding protein 2 | 0.0321799 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.032144 |
| FAM13B | family with sequence similarity 13, member B | 0.032039 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0319934 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317922 |
| SPAG9 | sperm associated antigen 9 | 0.0317272 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0315805 |
| MYO1E | myosin IE | 0.0314691 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0313698 |
| STK17A | serine/threonine kinase 17a | 0.0312634 |
| PARD3 | par-3 family cell polarity regulator | 0.0307934 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0303041 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0302267 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0301416 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0300931 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297196 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0295756 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0293813 |
| FBXO11 | F-box protein 11 | 0.0293784 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0292141 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0292105 |
| DTNA | dystrobrevin, alpha | 0.0289555 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0287936 |
| WDR26 | WD repeat domain 26 | 0.0281337 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0278531 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.02777 |
| MYO9A | myosin IXA | 0.02755 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0269627 |
| CEP350 | centrosomal protein 350kDa | 0.026925 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.026689 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0266871 |
| SNX9 | sorting nexin 9 | 0.0264084 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0263182 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0262191 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0255253 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0254447 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0253486 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0253369 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0252977 |
| WDR45B | WD repeat domain 45B | 0.0252154 |
| CD58 | CD58 molecule | 0.0251985 |
| RBM25 | RNA binding motif protein 25 | 0.0251835 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0247704 |
| ZNF292 | zinc finger protein 292 | 0.0246412 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC16 | mucin 16, cell surface associated | -0.100609 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.073956 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0679339 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0606714 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0518833 |
| PTMA | prothymosin, alpha | -0.0515276 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0502563 |
| RPS6 | ribosomal protein S6 | -0.0483819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0480118 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0469292 |
| ATOSA | atos homolog A | -0.0458305 |
| RPS25 | ribosomal protein S25 | -0.0449456 |
| RPLP0 | ribosomal protein, large, P0 | -0.0440758 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0436696 |
| RPS24 | ribosomal protein S24 | -0.0427615 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0426123 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0420258 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0405501 |
| S100A9 | S100 calcium binding protein A9 | -0.0394641 |
| RPS17 | ribosomal protein S17 | -0.039021 |
| ACTG1 | actin gamma 1 | -0.0379741 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0378474 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0374614 |
| RPS29 | ribosomal protein S29 | -0.0366148 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0353227 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0351542 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0345687 |
| POTEF | POTE ankyrin domain family, member F | -0.0342783 |
| RPL15 | ribosomal protein L15 | -0.0341283 |
| RPS3 | ribosomal protein S3 | -0.0341161 |
| IGF2 | insulin-like growth factor 2 | -0.0340609 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0338667 |
| RREB1 | ras responsive element binding protein 1 | -0.0333956 |
| RPL35A | ribosomal protein L35a | -0.0330375 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0326588 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0326149 |
| RPS27A | ribosomal protein S27a | -0.0325663 |
| CNKSR3 | CNKSR family member 3 | -0.0322502 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0309986 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0307551 |
| RPL37 | ribosomal protein L37 | -0.0307354 |
| VRK2 | vaccinia related kinase 2 | -0.0307077 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0306542 |
| ERBIN | erbb2 interacting protein | -0.0305468 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0303302 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0298737 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0298271 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0296259 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0295444 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0295237 |
| FTL | ferritin, light polypeptide | -0.0286581 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0285065 |
| SEC24D | SEC24 family member D | -0.0283398 |
| STEAP4 | STEAP family member 4 | -0.0282853 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0281643 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0277561 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.027593 |
| SECISBP2L | SECIS binding protein 2-like | -0.0273255 |
| GPATCH8 | G patch domain containing 8 | -0.0272994 |
| GPATCH2L | G patch domain containing 2-like | -0.0272938 |
| AHNAK | AHNAK nucleoprotein | -0.0270304 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.0267302 |
| RBM47 | RNA binding motif protein 47 | -0.0266069 |
| EGR1 | early growth response 1 | -0.0264035 |
| RPL34 | ribosomal protein L34 | -0.0263139 |
| MYOF | myoferlin | -0.0261622 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0260776 |
| RPS21 | ribosomal protein S21 | -0.02588 |
| RPS14 | ribosomal protein S14 | -0.0257382 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0251408 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0247811 |
| UBC | ubiquitin C | -0.0247796 |
| THOC2 | THO complex 2 | -0.0245186 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0244898 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0244864 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0244135 |
| TJP2 | tight junction protein 2 | -0.0243254 |
| DIAPH1 | diaphanous-related formin 1 | -0.0241888 |
| MYO9B | myosin IXB | -0.0241289 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0240643 |
| SVIL | supervillin | -0.0240139 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0240083 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0239711 |
| RPL28 | ribosomal protein L28 | -0.0237397 |
| ZNF638 | zinc finger protein 638 | -0.0237175 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0235622 |
| SEPTIN2 | septin 2 | -0.0235179 |
| TUFT1 | tuftelin 1 | -0.0234033 |
| RPS19 | ribosomal protein S19 | -0.0232198 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0229861 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0228497 |
| TPM4 | tropomyosin 4 | -0.022627 |
| JMJD1C | jumonji domain containing 1C | -0.0225366 |
| USP6NL | USP6 N-terminal like | -0.0224918 |
| RHOA | ras homolog family member A | -0.0222493 |
| KRT19 | keratin 19, type I | -0.0221214 |
| VMP1 | vacuole membrane protein 1 | -0.0219844 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0218705 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0216955 |
| RESF1 | retroelement silencing factor 1 | -0.0215375 |
