| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Saquinavir perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Saquinavir_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.147678 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0858236 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0823886 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0750394 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0723662 |
| VIM | vimentin | 0.0721585 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0678668 |
| KYNU | kynureninase | 0.0665939 |
| RPLP0 | ribosomal protein, large, P0 | 0.0649122 |
| MT2A | metallothionein 2A | 0.0616866 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0610419 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0598439 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0582654 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.058046 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0575475 |
| EFNA5 | ephrin-A5 | 0.0562515 |
| GRAMD1B | GRAM domain containing 1B | 0.0528212 |
| PDE10A | phosphodiesterase 10A | 0.0527493 |
| NEK7 | NIMA-related kinase 7 | 0.0514877 |
| RPS12 | ribosomal protein S12 | 0.0505264 |
| MCL1 | myeloid cell leukemia 1 | 0.0482869 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0477001 |
| RPS8 | ribosomal protein S8 | 0.0476536 |
| MFF | mitochondrial fission factor | 0.0447802 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0424498 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0424218 |
| PYGL | phosphorylase, glycogen, liver | 0.0419111 |
| ASPH | aspartate beta-hydroxylase | 0.0410878 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0402907 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0399765 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0391559 |
| RPS24 | ribosomal protein S24 | 0.0384596 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0383748 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0383413 |
| JMJD1C | jumonji domain containing 1C | 0.037835 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0377285 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0371897 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0371184 |
| RPS3 | ribosomal protein S3 | 0.0366777 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0351933 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0348114 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0346168 |
| CD109 | CD109 molecule | 0.0343426 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0342113 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0335818 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0335134 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.033482 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0334766 |
| LDHA | lactate dehydrogenase A | 0.0329226 |
| EXOC6B | exocyst complex component 6B | 0.0329138 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0322312 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0317384 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0316234 |
| DST | dystonin | 0.031595 |
| EXT1 | exostosin glycosyltransferase 1 | 0.031082 |
| RACK1 | receptor for activated C kinase 1 | 0.030374 |
| PLCB4 | phospholipase C, beta 4 | 0.0301777 |
| OSMR | oncostatin M receptor | 0.0297363 |
| STC1 | stanniocalcin 1 | 0.029628 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0294327 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0280043 |
| RPL39 | ribosomal protein L39 | 0.0279592 |
| ATXN1 | ataxin 1 | 0.0279225 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0277082 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0276824 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0274826 |
| S100A6 | S100 calcium binding protein A6 | 0.0271197 |
| RAD51B | RAD51 paralog B | 0.026977 |
| CCDC6 | coiled-coil domain containing 6 | 0.0266298 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0265202 |
| UBC | ubiquitin C | 0.0262839 |
| KIAA0825 | KIAA0825 | 0.0260406 |
| EXOC4 | exocyst complex component 4 | 0.0258393 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0258038 |
| SMAD2 | SMAD family member 2 | 0.0254274 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0251943 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0250756 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0246808 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0244588 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0244539 |
| ANXA1 | annexin A1 | 0.0243524 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0242983 |
| USP34 | ubiquitin specific peptidase 34 | 0.0240486 |
| HDAC4 | histone deacetylase 4 | 0.0240281 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0238804 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0238183 |
| RPS16 | ribosomal protein S16 | 0.0238094 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0237875 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0236432 |
| ENAH | enabled homolog (Drosophila) | 0.0233615 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0232633 |
| FNDC3A | fibronectin type III domain containing 3A | 0.023223 |
| PERP | PERP, TP53 apoptosis effector | 0.0231233 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0228028 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0226462 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0225797 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0225499 |
| LSAMP | limbic system-associated membrane protein | 0.0223265 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0222804 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0222731 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.349512 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.160485 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139959 |
| PTMA | prothymosin, alpha | -0.0805819 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.070201 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0700905 |
| COL5A2 | collagen, type V, alpha 2 | -0.0632617 |
| TMSB10 | thymosin beta 10 | -0.0581922 |
| RPS6 | ribosomal protein S6 | -0.0577879 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0562657 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0552716 |
| CANX | calnexin | -0.0552692 |
| MYOF | myoferlin | -0.0483799 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0424578 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0391891 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0389709 |
| GOLGA4 | golgin A4 | -0.037343 |
| MATR3 | matrin 3 | -0.0330541 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0329945 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0322271 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0311685 |
| RPL34 | ribosomal protein L34 | -0.0290539 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.028582 |
| RPL36 | ribosomal protein L36 | -0.0284851 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0283578 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0279172 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0276663 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0269017 |
| HLA-B | major histocompatibility complex, class I, B | -0.0264271 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.02617 |
| RPLP2 | ribosomal protein, large, P2 | -0.0259 |
| NBEAL1 | neurobeachin-like 1 | -0.0258243 |
| TENM3 | teneurin transmembrane protein 3 | -0.0257227 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.02511 |
| RPS19 | ribosomal protein S19 | -0.0245193 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.023866 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0236136 |
| RPL38 | ribosomal protein L38 | -0.0234328 |
| STC2 | stanniocalcin 2 | -0.0233476 |
| CTBP2 | C-terminal binding protein 2 | -0.0224369 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0222414 |
| RPL23 | ribosomal protein L23 | -0.0221561 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0219045 |
| SBF2 | SET binding factor 2 | -0.0207101 |
| RPLP1 | ribosomal protein, large, P1 | -0.0206422 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0199072 |
| RPL14 | ribosomal protein L14 | -0.0196091 |
| RPL35 | ribosomal protein L35 | -0.0195032 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | -0.0192791 |
| HYOU1 | hypoxia up-regulated 1 | -0.0192276 |
| GNAS | GNAS complex locus | -0.0188704 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0188699 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0188042 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0188003 |
| PCBP3 | poly(rC) binding protein 3 | -0.0187391 |
| NEDD1 | neural precursor cell expressed, developmentally down-regulated 1 | -0.01859 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0184541 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0184507 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0184113 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0183952 |
| LAMB1 | laminin, beta 1 | -0.0178191 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0174468 |
| SEPTIN10 | septin 10 | -0.0173881 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0173853 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0171103 |
| COPA | coatomer protein complex, subunit alpha | -0.0170697 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0170589 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0170307 |
| SMAP1 | small ArfGAP 1 | -0.0169597 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0169349 |
| TPR | translocated promoter region, nuclear basket protein | -0.0169046 |
| VEGFA | vascular endothelial growth factor A | -0.0167416 |
| LAMA5 | laminin, alpha 5 | -0.016594 |
| TBXT | T-box transcription factor T | -0.0163731 |
| NRCAM | neuronal cell adhesion molecule | -0.0162355 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0160851 |
| TKT | transketolase | -0.0160584 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0160069 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.015999 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0159916 |
| HLA-A | major histocompatibility complex, class I, A | -0.0159738 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0159301 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0158747 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0156096 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0153944 |
| CTSL | cathepsin L | -0.0153353 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0152323 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0150595 |
| OGA | O-GlcNAcase | -0.0149416 |
| YEATS2 | YEATS domain containing 2 | -0.0148178 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0146382 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0146053 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0145893 |
| USP37 | ubiquitin specific peptidase 37 | -0.0145098 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0144515 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0144347 |
| DNER | delta/notch-like EGF repeat containing | -0.0143597 |
| MPZL1 | myelin protein zero-like 1 | -0.0142354 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0141981 |
| CHD3 | chromodomain helicase DNA binding protein 3 | -0.0141838 |
